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SODIUM GLYCINATE


EC / List no.: 227-842-3
CAS no.: 6000-44-8
Mol. formula: C2H5NO2.Na

Sodium glycinate, a type of amino acid salt, is one of the potential solvent for carbon dioxide removal from various gas streams. 
Physicochemical properties such as density, viscosity and refractive index of aqueous sodium glycinate at low concentrations were measured from 303.15 to 333.15 K. 
Sodium glycinate was found that, the densities, viscosities and refractive indices of low concentrated sodium glycinate decrease with an increase in temperature, whereas with increasing the concentration in the solution, all three properties increase. 
The experimental data were correlated with respect to temperature and concentration by establishing the proper correlations.


Industry Uses    
Finishing agents

Intermediates


General Manufacturing Information    
Industry Processing Sectors
All other chemical product and preparation manufacturing
Textiles, apparel, and leather manufacturing


Sodium glycinate (Cly) is a natural amino acid neurotransmitter that acts as a co-agonist at Glutamate [NMDA] receptors in the brain and is an activator of Sodium glycinate receptors, GLRA1-3, GLRB. 
The abnormal Gly levels have been implicated in neuropsychiatric disorders.
Alterations in Gly levels are implicated in several diseases of the central nervous system. 
Sodium glycinate was studied in phase II of clinical trials in patients with schizophrenia. 
The results have shown that using of Sodium glycinate was associated with reduced symptoms with promising effect sizes and a possibility of improvement in cognitive function. 
Besides, Sodium glycinate was also studied in clinical trials phase II in children with cystic fibrosis. 
The clinical, spirometric and inflammatory status of subjects with cystic fibrosis improved after just 8 weeks of Sodium glycinate intake, suggesting that this amino acid might constitute a novel therapeutic tool for these patients. In addition, Gly was proposed as a biomarker for brain tumor malignancy. 
Sodium glycinate is a component of a nutrients mixture for peripheral administration to well-nourished mildly catabolic adult patients who require only short-term parenteral nutrition.

The physical solubility and diffusivity of N2O and CO2 in aqueous sodium glycinate (SG) solutions of various concentrations (1.0−3.5 kmol/m3) and temperatures (303.15−323.15 K) were reported. 
The kinetics of the reaction between CO2 and SG has been studied using absorption data measured by a wetted-wall column apparatus at various temperatures and concentrations. 
The second-order rate constant of CO2 with SG was determined to be k2(m3 kmol-1 s-1) = 1.95 × 1013 exp(−7670/T), where T is the absolute temperature (given in Kelvin). 
The activation energy for the reaction of CO2 with SG was calculated to be 63.8 kJ/mol.

The physicochemical properties of  sodium glycinate solution such as density, viscosity, surface tension, alkalinity, and pH were measured over a wide range of mass fraction (0.1 to 0.5) of sodium glycinate and at T = (303.15 to 353.15) K. 
The measured data were correlated with standard equations, and parameters were reported along with average absolute deviations.


Sodium glycinate is a Sodium salt of glycine Sodium glycinate uses and applications include: 
Flavor modifier in foods.
Suggested storage of Sodium glycinate: Store in cool, dry place 
R.T.; keep tightly closed


APPLICATIONS
Flavor enhancers and maskers, pH buffers and stabilizers, an ingredient in pharmaceutical products, food and personal care products and as a chemical intermediate used in detergent and electroplating industry.

Sodium glycinate, also known as Sodium amino-acetate.CAS no. : 6000-44-8, molecular formula: NH2CH2COONa, EINECS no. : 227-842-3.
The solid sodium glycine is a white or pale yellow crystalline powder.Hygroscopicity, soluble in water.Boiling point 240.9 ℃;Flash point: 99.5℃;Molecular weight: 97.7.
Other information
1. Storage and transportation of sodium glycine (6000-44-8) : sealed and stored in a cool, ventilated and dry place.
2. Safety instructions: avoid prolonged contact and clean thoroughly after use.


About Sodium glycinate
Helpful information
Sodium glycinate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

Sodium glycinate is used at industrial sites and in manufacturing.

Consumer Uses
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment.

Article service life
ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using Sodium glycinate. ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment.

Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment.

Uses at industrial sites
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using Sodium glycinate. ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment.

Manufacture
ECHA has no public registered data on the routes by which Sodium glycinate is most likely to be released to the environment.


IUPAC NAMES:
Glycine monosodium salt; Sodium glycinate
sodium 2-aminoacetate
sodium aminoacetate
Sodium glycinate
sodium glycinate
Sodium Glycinate
sodium;2-aminoacetate


SYNONYMS:
GLYCINE SODIUM SALT
GLYCOCOLL SODIUM SALT
AMINODIACETIC ACID SODIUM SALT
AMINOETHANOIC ACID SODIUM SALT
AMINOACETIC ACID SODIUM SALT
SODIUM AMINOACETATE
SODIUM GLYCINATE
Aminoethanoic acid Glycocoll
glycocollate
Glycine sodiu
sodiuM 2-aMinoacetate
Aminoacetic acid, Aminoethanoic acid, Glycocoll, Sodium glycinate
2-Aminoacetic acid sodium salt
Glycine, sodiuM salt (1:1)
Sodium GlyClnate
Glycine sodium salt, >=98.5%
Glycine sodium salt anhydrous
Glycine monosodium salt Sodium glycinate sodium aminoacetate sodium glycocollate Aminoacetic acid Aminoethanoic acid Glycocoll
Glycine,monosodiumsalt
sodiumglycine
sodiumglycocollate
Sodiumaminoaceticacid
Glycinate magnesium
H-Gly-ONa
Glycine sodium
Glycine sldium
SODUM GLYCINATE
Glycine Sodum
SODIUM GLYCINATE USP/EP/BP
Sodium Bisglycinate
Glycine Sodium Hydrate
Sodium glycinate
6000-44-8
sodium 2-aminoacetate
Glycine sodium sal
Glycine, monosodium salt
sodium;2-aminoacetate
GLYCINE, SODIUM SALT
Glycine, sodium salt (1:1)
Sodum glycinate
EINECS 227-842-3
UNII-F6B979BV8Z
F6B979BV8
Sodium glycine
Sodium aminoacetate
Sodium glycocollate
Glycine, sodium salt, 99%
MFCD0015068
Glycine, sodium salt solution
PubChem9921
Glycine Sodium Hydrate
H2NCH2COONa
sodium 2-azanylethanoate
C2H4NNaO2


 

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