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SODIUM ISETHIONATE

CAS NUMBER: 1562-00-1

EC NUMBER: 216-343-6

MOLECULAR FORMULA: C2H5NaO4S

MOLECULAR WEIGHT: 148.12

IUPAC NAME: sodium;2-hydroxyethanesulfonate


Sodium Isethionate (also: Sodium 2-hydroxyethyl sulfonate) is the sodium salt of 2-hydroxyethane sulfonic acid (isethionic acid), it is used as a hydrophilic head group in washing-active surfactants, known as isethionates (acyloxyethanesulfonates) due to its strong polarity and resistance to multivalent ions. 
Sodium Isethionate is being studied as a high production volume chemical in the "High Production Volume (HPV) Chemical Challenge Program" of the US Environmental Protection Ministry EPA.

Properties:
Solid sodium 2-hydroxyethyl sulfonate is a colorless, free-flowing, non-hygroscopic solid, which dissolves readily in water and has good biodegradability. 
Due to the method of synthesis samples often contain traces of sodium sulfite or sodium hydrogen sulfite causing aqueous solution to possesses a mildly alkaline pH of about 10.

Uses:
The main use of sodium 2-hydroxyethyl sulfonate is the production of the isethionate class of surfactants. 
These are readily foaming and particularly mild, making them suitable for cleaning sensitive skin and are therefore mainly used in baby soaps and shampoos.
Because of its pronounced skin compatibility sodium 2-hydroxyethyl sulfonate is added to soaps and liquid skin cleansers with up to 15 parts by weight.

From sodium 2-hydroxyethyl sulfonate the so-called biological buffers such as HEPES, MES, PIPES etc. are easily accessible.
The addition of 2-hydroxyethyl sulfonate to electroplating baths allows higher current densities and lower concentrations than the much more expensive methane sulphonic acid with improved appearance.
Sodium isethionate,more commonly called Sodium Isethionate,is a sodium salt derived from coconut oil. 
Sodium Isethionate's a common ingredient that is often used as a replacement for animal-derived sodium salts

Sodium Isethionate finds its way into soaps and cleansers because it acts as a surfactant, which means that it helps to bind chemical compounds that don't typically dissolve in water. 
In the case of its use in soaps, it helps water cling to the dirt and oil on your skin, allowing them to be washed away.
Because of its mild nature, it's also often found in toothpastes and in baby soaps, too.
Sodium Isethionate is a colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid

What Is Sodium Isethionate?
Sodium isethionate is a fine white powder derived from the fatty acids in coconut oil and isethionic acid, a type of sulfonic acid.
Coconuts grow on cocos nucifera trees and are widely cultivated to produce:

-fibers
-building materials
-natural ingredients

How Is Sodium Isethionate Made?
Sodium isethionate is made by reacting sodium isethionate with the fatty acid from coconut oil or other chlorides.
Next, the mixture is heated to remove water and then distilled to remove excess fatty acids

Sodium Isethionate Uses:
Sodium isethionate is a surfactant that allows water, oil and dirt to mix, allowing things to become cleaner.
Sodium Isethionate can be found in dozens of personal care products such as shampoo

-facial cleanser
-bar soaps
-conditioners
-hair styling products

Is Sodium Isethionate Safe?
The Cosmetics Ingredient Review has deemed the ingredient safe for use in cosmetic products when formulated to be non irritating.
Whole Foods has deemed the ingredient acceptable in its body care quality standards.
Clinical research has shown that the ingredient is typically not a skin irritant or sensitizer

Sodium Isethionate works as an amphoteric detergent and can also be used as an intermediate in preparing surfactants derived from fatty acid sulfoalkyl esters (acyloxy ethane sulfonate).
Sodium Isethionate increases the formulation's stability, improves the detergency in hard water, and is smooth to the skin. 
These features are commonly used in the Home Care and I&I, and Personal Care markets in soap and shampoo formulations. 
Sodium Isethionates benefits in the final product are highly appreciated by consumers, such as abundant foam and reduced soap residue on the skin, in addition to being a major antistatic agent in shampoos. 

Commonly known as Baby Foam due to its exceptional mildness, Sodium Isethionate Raw Material is a surfactant that is comprised of a type of sulphonic acid called Isethionic Acid as well as the fatty acid- or sodium salt ester-obtained from Coconut Oil. 
Sodium Isethionate is a traditional substitute for sodium salts that are derived from animals, namely sheep and cattle.
Sodium Isethionate exhibits high foaming ability, producing a stable, rich and velvety lather that does not dehydrate the skin, making it ideal for addition to water-free products as well as skin care, hair care, and bath products. 
This high-performance surfactant, which is equally effective in both hard and soft water, is a popular choice for addition to liquid shampoos and bar shampoos, liquid soaps and bar soaps, bath butters and bath bombs, and to shower gels, to name a few foaming products

-Purity / Analysis Method: >98.0%(T)  
-Physical State (20 C): Solid
-Store Under Inert Gas: Store under inert gas
-Condition to Avoid: Hygroscopic
-Reaxys Registry Number: 3633992
-PubChem Substance ID: 87570669
-MDL Number: MFCD00007534

This lightly-scented and conditioning cleansing agent is gentle enough for use on the delicate skin of babies, making it an ideal surfactant for makeup as well as personal care products and natural toiletries. 
Sodium Isethionates emulsifying property, which allows water and oil to mix, makes it a popular ingredient in soaps and shampoos, as it encourages dirt to attach itself to them, which in turn makes it easier for it to be washed away. 
Sodium Isethionates deluxe foaming capacity and conditioning effects leave the hair and skin feeling hydrated, soft, and silky-smoothe.

To incorporate Sodium Isethionate into a formulation, it is recommended that the chips be crushed prior to melting, as this helps to increase their melting rate.
Sodium Isethionate must be heated slowly on low heat in order to allow for easy mixing with other surfactants. 
Sodium Isethionate is recommended that the surfactant phase be mixed using a high shear stick blender. 
This approach helps to prevent the excess foaming that could potentially occur if the stick blender is used to mix all ingredients together at once. 

Finally, the surfactant mixture can be added to the rest of the formulation.
Sodium Isethionate is a sodium salt ester, or a fatty acid derived from coconut oil. 
Sodium Isethionate is used in cosmetics and personal care products as a surfactant and is often seen in hair care products like shampoos because of its ability to help water to mix with oil and dirt, allowing them to be more easily rinsed away, according to CosmeticsInfo.org. 
Sodium Isethionate is also seen as an ingredient in a variety of soaps and cleansing products. 
As a surfactant, it creates a wet feeling, it solubilizes oils and reduces surface tension, and can aid in foaming as well.

SODIUM ISETHIONATE is classified as :

-Antistatic
-Cleansing
-Hair conditioning
-Skin conditioning

Sodium Isethionate is a gentle surfactant derived from coconut. 
Sodium Isethionate can be used in a variety of cosmetic recipes. 
Sodium Isethioniate acts as a foaming and cleansing ingredient. 
Sodium Isethionate leaves your skin feeling soft and silky. 
This is an ingredient used in products like soap, bath bombs, bubble bars, and shampoo.

Sodium Isethionate has been a predominant ingredient in syndet bar formulation for more than thirty years. 
Although cost effective and well recognized for good skin compatibility
Sodium Isethionate is not regularly found in liquid detergent systems due to its limited solubility in water. 
This study focuses on the understanding of enthalpy of solubilization, equilibrium of solubilization, and the structures and properties of Sodium Isethionate and various surfactants. 

The purpose of this exercise is to help the formulator to find appropriate surfactant systems to keep Sodium Isethionate in aqueous solution. 
The solubility of Sodium Isethionate in water is unfavorable in terms of enthalpy of solvation. 
When setting up equilibrium of solubilization, there are three possible phases, and three methods have been developed to prevent Sodium Isethionate from recrystallizing in aqueous solutions. 

The first focuses on tying cocoyl isethionate ions within micelles made of secondary surfactants. 
The second focuses on the exchange of sodium ions with ammonium ions (and/or triethanolammonium). 
The third centers on emulsification of Sodium Isethionate and the subsequent change of micelles into emulsified oil drops. 
A combination of two or three of these methods will enable the formulator to use Sodium Isethionate as the primary surfactant in liquid detersive system.

Sodium isethionate is a mild surfactant (cleansing agent) derived from isethionic acid and coconut fatty acids. 
In its raw state, it usually appears as white granular solids.
Sodium isethionate can be used in personal care products as a gentle surfactant, helping to mix water with oil and dirt so they can be washed away, without stripping the skin's natural barrier. 
Like many coconut-derived cleansers, it also contributes to lather, producing a luxurious creamy foam that does not dry out skin. 
Sodium Isethionates ultra-mild properties make it ideal for delicate or sensitive skin, and it is often used as a plant-based alternative to animal-derived sodium salts.

APPLICATIONS:

-antistatic        
-antistatic agent        
-cleansing        
-hair conditioning        
-Personal care products
-Industry
-Household Products
-facial cleanser
-bar soaps
-conditioners
-hair styling products
-liquid soaps
-bath butters
-bath bombs
-shower gels
-foaming products

Sodium isethionate is a cleansing ingredient used in skincare and haircare formulations. 
Sodium isethionate is derived from coconut oil. 
Sodium Isethionate is primarily used in soaps, cleansers, shampoos, and cleansing products due to its surfactant abilities. 
Surfactants help to lift oil and dirt from the skin allows it to be washed away. 
This is why sodium cocoyl isethionate can be found in products that help to cleanse the skin and hair. 

Sodium isethionate is used as a fine white powder that has a mild scent. 
Sodium Isethionate is usually used in concentrations that range between 10-25%. 
There are considered to be no issues with irritation, sensitivity, or toxicity at these concentrations. 

Sodium isethionate functions primarily as a surfactant-cleansing agent and the majority of the uses reported are in coloring and non-coloring hair products
Sodium Isethionate is a sodium salt derived from coconut oil. 
Sodium Isethionate’s a common replacement for animal-derived sodium salts like sodium tallowate, which is derived from cattle and sheep. 

Sodium isethionate acts as a surfactant in soaps and cleansers
Sodium Isethionate lowers the surface tension of water, which makes the cleanser easier to spread on your face when you wash it, and helps water and oil bond. 
Basically, sodium isethionate helps water cling to the dirt and oil on your skin, allowing it to be washed away. 
Because of sodium isethionate’s mild nature, it’s often found in toothpastes and in baby soaps.

Sodium isethionate is derived from coconut, and is a mild soap-free cleansing agent known for its ability to mitigate disruption to skin's barrier; compatible with sensitive skin
Sodium cocoyl isethionate (SCI) is a solid surfactant that makes shampoos and soaps foam and cleans.
Surfactants are organic compounds with a hydrophobic tail and a hydrophilic head.

This means they attract oil and water, helping all of the different ingredients in a formula blend together. 
Sodium Isethionate also means that they can attract sebum and dirt from the skin and hair and allow them to be washed off with water.
Derived from the fatty acids in coconut oil, SCI is known to be very gentle on the skin and scalp, which is why it is sometimes referred to as "baby foam". 
This compound is a good sulfate-free alternative for people who want to avoid commonly known surfactants such as sodium lauryl sulfate (SLS).

PHYSICAL PROPERTIES OF SODIUM ISETHIONATE:

-Molecular Weight: 148.12    

-Exact Mass: 147.98062409    

-Monoisotopic Mass: 147.98062409    

-Topological Polar Surface Area: 85.8 Ų    

-Physical Description: Liquid

-Melting point: 191 °C -194 °C 

-Form: powder or solid particle

-Fragrance: pleasant scent

-Color: white


CHEMICAL PROPERTIES OF SODIUM ISETHIONATE:

-Hydrogen Bond Donor Count: 1    

-Hydrogen Bond Acceptor Count: 4    

-Rotatable Bond Count: 2    

-Heavy Atom Count: 8    

-Formal Charge: 0    

-Complexity: 122    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 2    

-Compound Is Canonicalized: Yes

Sodium Isethionate is a mild primary surfactant with a dense, luxurious foam.
Sodium Isethionate is mild on the skin, and non-drying. 
Sodium isethionate can be combined with other surfactants to make an elegant creamy shampoo and body wash. 
Sodium Isethionate can be used as the only surfactant in a cream or solid bar cleanser. 

In both hair and skin care applications this surfactant creates an elegant feel during use and a conditined afterfeel. 
Physical Form: easy to handle white noodles. 
Sodium isethionate works equally well in soft or hard water. 
Sodium Isethionate is also an anti-static agent in shampoos.

Commonly known as Baby Foam due to its exceptional mildness, Sodium Isethionate Raw Material is a surfactant that is comprised of a type of sulphonic acid called Isethionic Acid as well as the fatty acid – or sodium salt ester – obtained from Coconut Oil. 
Sodium Isethionate is a traditional substitute for sodium salts that are derived from animals, namely sheep and cattle.
Sodium Isethionate exhibits high foaming ability, producing a stable, rich and velvety lather that does not dehydrate the skin, making it ideal for addition to water-free products as well as skin care, hair care, and bath products. This high-performance surfactant, which is equally effective in both hard and soft water, is a popular choice for addition to liquid shampoos and bar shampoos, liquid soaps and bar soaps, bath butters and bath bombs, and to shower gels, to name a few foaming products.

Sodium Isethionate functions as a:

-Cleanser
-Foaming Agent
-Emollient
-Moisturizer
-Conditioner
-Softener

It helps to:
-Lift and remove dirt
-Hydrate the hair and skin to protect against dryness
-Create rich, foaming lather
-Prevent frizz
-Increase product viscosity
-Moisturize, condition, and soften
-Reduce tangling
-Emulsify formulations and increase their viscosity, which contributes a creamier texture
-Lift and remove dirt
-Soothe skin
-Hydrate, condition, and soften the skin to reduce irritation, cracking, and peeling

This lightly-scented and conditioning cleansing agent is gentle enough for use on the delicate skin of babies, making it an ideal surfactant for makeup as well as personal care products and natural toiletries. 
Sodium Isethionates emulsifying property, which allows water and oil to mix, makes it a popular ingredient in soaps and shampoos, as it encourages dirt to attach itself to them, which in turn makes it easier for it to be washed away. 
Sodium Isethionates deluxe foaming capacity and conditioning effects leave the hair and skin feeling hydrated, soft, and silky-smoothe.

To incorporate Sodium Isethionate into a formulation, it is recommended that the chips be crushed prior to melting, as this helps to increase their melting rate. 
Sodium Isethionate must be heated slowly on low heat in order to allow for easy mixing with other surfactants. 
Sodium Isethionate is recommended that the surfactant phase be mixed using a high shear stick blender. 
This approach helps to prevent the excess foaming that could potentially occur if the stick blender is used to mix all ingredients together at once. 
the surfactant mixture can be added to the rest of the formulation.

These features are commonly used in the Home Care and I&I, and Personal Care markets in soap and shampoo formulations. 
Sodium Isethionates benefits in the final product are highly appreciated by consumers, such as abundant foam and reduced soap residue on the skin, in addition to being a major antistatic agent in shampoos. 
As with all other New Directions Aromatics products, Sodium Isethionate Raw Material is for external use only.
This product can be used as a therapeutic agent by consulting a doctor.

SYNONYMS:

Sodium 2-hydroxyethanesulfonate
Isethionic acid sodium salt
2-Hydroxyethanesulfonic acid sodium salt
Sodium hydroxyethylsulfonate
Ethanesulfonic acid, 2-hydroxy-, monosodium salt
Sodium beta-hydroxyethanesulfonate
Ethanesulfonic acid, 2-hydroxy-, sodium salt (1:1)
2-hydroxy-ethanesulfonate
Sodium 2-hydroxyethanesulphonate
Isethionic acid, sodium salt, 98%
Sodium 1-hydroxy-2-ethanesulfonate;
Sodium 2-hydroxy-1-ethanesulfonate; 
Sodium 2-hydroxyethanesulfonate
Sodium 2-hydroxyethylsulfonate
Sodium 1-hydroxy-2-ethanesulfonate
Sodium 2-hydroxy-1-ethanesulfonate
Ethanesulfonic acid, 2-hydroxy-, sodium salt
isethionic acid sodium
2-Hydroxyethanesulfonic acid, sodium salt
Isethionic acid, sodium salt
Istethionic Acid Sodium Salt
Sodium 2-Hydroxy-Ethanesulfonate
Isethionic acid sodium salt, 98%
2-hydroxyethanesulfonic acid; sodium
Tox21_200227
2-Hydroxy Ethanesulphonic Acid Sodium Salt, 
Isethionic Acid Sodium Salt, 
Ethanol Sulphonic Acid Sodium Salt

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