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Sodium Isethionate is the sodium salt of 2-hydroxyethane sulfonic acid (isethionic acid), it is used as a hydrophilic head group in washing-active surfactants, known as isethionates (acyloxyethanesulfonates) due to its strong polarity and resistance to multivalent ions.
Sodium Isethionate is being studied as a high production volume chemical in the "High Production Volume (HPV) Chemical Challenge Program" of the US Environmental Protection Agency (EPA).
Sodium Isethionate is synthesized by the condensation reaction of sodium bisulfite and ethylene oxide.
CAS: 1562-00-1
MF: C2H5NaO4S
MW: 148.11
EINECS: 216-343-6
Synonyms
sodium2-hydroxyethylsulfonate;sodiumbeta-hydroxyethanesulfonate;Ethanesulfonic acid, 2-hydroxy-, sodium salt (1:1);2-HydroxyethanesuL;phonic acid;Ethanesulfonicacid,2-hydroxy-,monosodiumsalt;sodium2-hydroxy-1-ethanesulfonate;2-Hydroxyethansulfonsure, Na-Salz
Sodium Isethionate is a mild, anionic surfactant widely used in personal care and cleansing formulations.
Also known as isethionic acid sodium salt or sodium 2-hydroxyethyl sulfonate, Sodium Isethionate features excellent water solubility, high compatibility with other surfactants, and a gentle, skin-friendly profile.
Sodium Isethionate is often used as a raw material in the production of mild surfactants such as Sodium Cocoyl Isethionate (SCI), which are popular in sulfate-free shampoos, facial cleansers, and body washes.
Sodium Isethionate is a mild, surfactant derived from coconut oil and isethionic acid.
Sodium Isethionate is an anionic surfactant used in a variety of personal care products for its mild cleansing and foaming properties.
Sodium Isethionate’s ideal for sensitive and dry skin, providing a rich, creamy lather without stripping moisture from the skin.
Sodium Isethionate's versatility, mildness, and biodegradability make it a preferred choice in natural and skin-friendly cleansing formulations, especially for facial cleansers, shampoos, and syndet bars.
Sodium Isethionate is used as a surfactant or co-surfactant (for cleansing properties and lather) in products such as shampoos, shampoo bars, body washes, and hand soaps.
Sodium Isethionate's created by combining sodium isethionate with coconut oil fatty acids.
Sodium Isethionate Chemical Properties
Melting point: 191-194 °C(lit.)
density: 1762.7[at 20℃]
bulk density: 800kg/m3
storage temp.: Store below +30°C.
solubility H2O: 0.1 g/mL, clear, colorless
form: Fine Powder
color: White
PH: 7.0-11.0 (20g/l, H2O, 20℃)
Water Solubility: SOLUBLE
BRN: 3633992
Stability: Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids.
Cosmetics Ingredients Functions CLEANSING
ANTISTATIC
HAIR CONDITIONING
SKIN CONDITIONING
InChI: InChI=1S/C2H6O4S.Na/c3-1-2-7(4,5)6;/h3H,1-2H2,(H,4,5,6);/q;+1/p-1
InChIKey: LADXKQRVAFSPTR-UHFFFAOYSA-M
LogP: -4.6 at 20℃
CAS DataBase Reference: 1562-00-1(CAS DataBase Reference)
EPA Substance Registry System: Sodium Isethionate (1562-00-1)
Sodium Isethionate is a colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid.
Sodium Isethionate is an organic salt and an important intermediate for pharmaceuticals, cosmetics and daily chemicals.
Sodium Isethionate is a colorless, free-flowing, non-hygroscopic solid, which dissolves readily in water and has good biodegradability.
Due to the method of synthesis samples often contain traces of sodium sulfite or sodium hydrogen sulfite causing aqueous solution to possesses a mildly alkaline pH of about 10.
Uses
Sodium Isethionate is an amphoteric detergent used in detergent bar soaps.
Sodium Isethionate makes a dense lather in addition to the lather made by the soap.
Sodium Isethionate is mild on the skin, and non-drying.
Sodium Isethionate works equally well in soft or hard water.
Sodium Isethionate is also an anti-static agent in shampoos.
Sodium Isethionate works as an amphoteric detergent and can also be used as an intermediate in preparing surfactants derived from fatty acid sulfoalkyl esters (acyloxy ethane sulfonate).
Sodium Isethionate increases the formulation's stability, improves the detergency in hard water, and is smooth to the skin.
Sodium Isethionate is used in cleaning/washing agents, disinfectants, cosmetics, surface-active agents, shampoos, and bubble baths.
The main use of Sodium Isethionate is the production of the isethionate class of surfactants.
These are readily foaming and particularly mild, making them suitable for cleaning sensitive skin and are therefore mainly used in baby soaps and shampoos.
Because of its pronounced skin compatibility sodium 2-hydroxyethyl sulfonate is added to soaps and liquid skin cleansers with up to 15 parts by weight.
From sodium 2-hydroxyethyl sulfonate the so-called biological buffers such as HEPES, MES, PIPES etc. are easily accessible.
The addition of 2-hydroxyethyl sulfonate to electroplating baths allows higher current densities and lower concentrations than the much more expensive methane sulphonic acid with improved appearance.
Sodium isethionate is a key ingredient in syndet (synthetic detergent) bars, facial cleansers, and shampoos.
Sodium Isethionate provides mild yet effective cleansing and helps maintain skin moisture without irritation.
When reacted with fatty acids, Sodium Isethionate forms Sodium Cocoyl Isethionate (SCI) — a gentle surfactant highly favored in sulfate-free formulations.
