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SODIUM LAUROYL ISETHIONATE

Sodium Lauroyl Isethionate is an ionic surfactant mainly used in laboratory research and development processes and chemical production processes.
Sodium Lauroyl Isethionate is the chemical name for the sodium salt of the methyl lauric acid ester of isethionic acid. 
Sodium Lauroyl Isethionate serves as a surfactant and cleaning agent in cosmetics and personal care items. 

CAS Number: 7381-01-3
Molecular Formula: C14H29NaO5S
Molecular Weight: 332.43
EINECS Number: 230-949-8

Synonyms:Sodium ethyl 2-sulfolaurate, Igepon A, Sodium lauroylisethionate, Sodium 2-sulfoethyl laurate, Sodium 2-sulfoethyldodecanoate, Sodium lauryl isethionate, 2-Sulfoethyl laurate sodium salt, Dodecanoic acid 2-sulfoethyl ester sodium salt, Lauroyl isethionate sodium salt, 2-Sulfoethyl dodecanoate sodium salt, Lauric acid ester with 2-hydroxyethanesulfonic acid sodium salt, Dodecanoic acid 2-sulfoethyl ester sodium salt (1:1), Sodium Lauroyl Isethionate, sodium 2-(dodecanoyloxy)ethanesulfonate, sodium 2-(dodecanoyloxy)ethane-1-sulfonate, Dodecanoic acid 2-(sodiooxysulfonyl)ethyl ester;Igepon A;Sodium 2-(dodecanoyloxy)ethanesulfonate;2-Sulfoethyl dodecanoate sodium salt;2-Sulfoethyl laurate sodium salt;Ccris 528;Dodecanoic acid, 2-sulfoethyl ester, sodium salt;Dodecanoic acid, 2-sulfoethyl ester, sodium salt (1:1)

Sodium Lauroyl Isethionate is a very gentle cleaning agent with rich, luxurious foam and a refined after-feel. 
Additionally, it is very well soluble in water, making it rinsable. 
Sodium Lauroyl Isethionate is an alternative to a more widely known surfactant, sodium cocoyl isethionate. 

As a raw material, sodium lauroyl methyl isethionate is often available as white-to-off-white flakes or chips.
Sodium Lauroyl Isethionate is a mild anionic surfactant, widely used as a cleansing and foaming agent in personal-care products such as soaps, shampoos, and body washes.
Its general chemical structure is based on a lauroyl (C12 fatty acid) group linked to isethionate and neutralized with sodium.

Sodium Lauroyl Isethionate belongs to the class of isethionate surfactants.
Sodium Lauroyl Isethionate consists of a hydrophobic lauroyl chain (derived from coconut fatty acids) and a hydrophilic isethionate sulfonate group (–SO₃⁻).
This amphiphilic structure enables interaction with both oils and water.

Sodium Lauroyl Isethionate provides effective surface activity.
Physically, sodium lauroyl isethionate appears as a white to off-white solid (flakes, granules, or powder).
Sodium Lauroyl Isethionate is dispersible in water and produces a creamy, stable foam.

Sodium Lauroyl Isethionate has a mild characteristic odor.
Sodium Lauroyl Isethionate exhibits excellent cleansing and foaming properties, producing dense, creamy lather.
It effectively removes dirt and oils.

Sodium Lauroyl Isethionate is known for its very mild skin compatibility, causing less irritation compared to sulfate-based surfactants.
It helps maintain skin moisture.
This makes it suitable for sensitive-skin formulations.

Sodium Lauroyl Isethionate shows good stability in mildly acidic to neutral pH conditions.
Sodium Lauroyl Isethionate exhibits strong interfacial activity, allowing it to effectively reduce surface tension between water and oils.
This enables efficient removal of sebum and dirt.

Sodium Lauroyl Isethionate supports gentle but effective cleansing.
The compound shows excellent compatibility with skin lipids, helping preserve the natural moisture barrier.
It does not excessively strip natural oils.

This contributes to a soft after-feel.
Sodium Lauroyl Isethionate demonstrates good performance in mildly acidic formulations, which match the natural pH of skin.
It remains stable and effective in these conditions.

Sodium Lauroyl Isethionate provides excellent rinseability, allowing products to wash off easily without residue.
This improves user experience.
Sodium Lauroyl Isethionate leaves a clean, smooth feel.

The surfactant has low eye and skin irritation potential, making it suitable for delicate applications.
Sodium Lauroyl Isethionate is commonly used in facial and baby products.
This highlights its mild nature.

Density: 1.21 [at 20℃]
vapor pressure: 0 Pa at 25℃
storage temp.: Sealed in dry, Room Temperature
pKa: 0.36 [at 20 ℃]
Water Solubility: 1.29 g/L at 20℃
Cosmetics Ingredients Functions: SURFACTANT - CLEANSING; SKIN CONDITIONING; HAIR CONDITIONING; FOAMING; CLEANSING; ANTISTATIC
InChI: InChI=1S/C14H28O5S.Na.H/c1-2-3-4-5-6-7-8-9-10-11-14(15)19-12-13-20(16,17)18;;/h2-13H2,1H3,(H,16,17,18);;
InChIKey: MPFFCOPKKKFBMI-UHFFFAOYSA-N
SMILES: C(=O)(OCCS(O)(=O)=O)CCCCCCCCCCC.[NaH]
LogP: 0.6 at 22℃

Sodium Lauroyl Isethionate belongs to the group of isethionate-based surfactants, known for combining effective cleansing with low irritation.
They are widely used as alternatives to sulfate surfactants.
This supports gentle formulations.

The molecule contains a sulfonate group (–SO₃⁻) rather than a sulfate group.
This structural feature reduces protein denaturation.
Sodium Lauroyl Isethionate contributes to improved skin mildness.

Sodium Lauroyl Isethionate produces a rich, creamy, and dense foam rather than large, airy bubbles.
The foam is stable and long-lasting.
This enhances user perception.

The surfactant shows good tolerance to hard water, maintaining performance in the presence of calcium and magnesium ions.
Sodium Lauroyl Isethionate is less affected by mineral content.
This ensures consistent cleansing.

Sodium Lauroyl Isethionate exhibits low irritation potential, even with frequent use.
It is suitable for sensitive skin and scalp.
This is important in daily-use products.

Sodium Lauroyl Isethionate is often used in synergistic blends with amphoteric or nonionic surfactants.
These combinations improve foam, viscosity, and mildness.
This enhances formulation flexibility.

Sodium Lauroyl Isethionate has good biodegradability, especially when derived from natural fatty acids.
Sodium Lauroyl Isethionate is considered environmentally favorable.
This supports sustainable product development.

Sodium Lauroyl Isethionate can influence viscosity and rheology, helping create creamy and stable textures.
It contributes to product thickness.
Sodium Lauroyl Isethionate is a high-performance, mild anionic surfactant with excellent foaming, skin compatibility, and formulation versatility, widely used in sulfate-free personal-care systems.

Sodium Lauroyl Isethionate maintains foam stability even in the presence of oils, ensuring consistent lather during use.
This is important for cleansing performance.
Sodium Lauroyl Isethionate enhances effectiveness.

Sodium Lauroyl Isethionate can help reduce the harshness of stronger surfactants when used in blends.
It acts as a mildness enhancer.
This improves overall formulation balance.

Sodium Lauroyl Isethionate contributes to smooth, creamy textures in both liquid and solid cleansers.
Sodium Lauroyl Isethionate improves product aesthetics.
Sodium Lauroyl Isethionate is a mild, efficient surfactant that balances cleansing power with skin compatibility, making it ideal for modern, sulfate-free personal-care formulations.

Uses:
Sodium Lauroyl Isethionate is widely used in shampoos and hair cleansers as a mild primary or co-surfactant.
Sodium Lauroyl Isethionate provides gentle cleansing and rich, creamy foam.
This improves hair softness and scalp comfort.

In body washes and shower gels, it functions as a cleansing and foaming agent.
Sodium Lauroyl Isethionate produces stable, dense lather.
This enhances user experience.

Sodium Lauroyl Isethionate is used in facial cleansers for gentle removal of dirt and oils.
Sodium Lauroyl Isethionate cleans without stripping natural moisture.
This makes it suitable for sensitive skin.

Sodium Lauroyl Isethionate is applied in baby-care products, such as baby shampoos and washes.
Its low irritation profile ensures gentle cleansing.
This protects delicate skin.

In syndet bars (synthetic detergent bars), it is a key surfactant component.
Sodium Lauroyl Isethionate provides structure and creamy foam.
This improves bar performance.

Sodium Lauroyl Isethionate is widely used in sulfate-free formulations as an alternative to harsher surfactants.
Sodium Lauroyl Isethionate maintains cleansing efficiency while reducing irritation.
This supports modern cosmetic trends.

In 2-in-1 shampoo and conditioning products, it contributes to both cleansing and a soft after-feel.
Sodium Lauroyl Isethionate works well with conditioning agents.
This enhances multifunctional formulations.

Sodium Lauroyl Isethionate is used in liquid hand soaps and hygiene products.
It enables effective cleaning with reduced skin irritation.
This supports frequent use.

Sodium Lauroyl Isethionate is also applied in premium and dermatological formulations where mildness is essential.
Sodium Lauroyl Isethionate helps maintain the skin barrier.
Sodium Lauroyl Isethionateis used wherever gentle cleansing, rich foam, and low irritation are required, especially in shampoos, body washes, facial cleansers, and sulfate-free personal-care products.

Sodium Lauroyl Isethionate is used in solid shampoo bars and cleansing bars as a primary surfactant.
Sodium Lauroyl Isethionate provides structure and creamy foam in water-free formats.
This supports solid cosmetic formulations.

In sensitive-skin and dermatological cleansers, it is selected for its mildness.
Sodium Lauroyl Isethionate cleans effectively without damaging the skin barrier.
This improves skin tolerance.

Sodium Lauroyl Isethionate is applied in after-sun and soothing cleansing products.
It gently removes impurities from irritated skin.
This enhances comfort and recovery.

Sodium Lauroyl Isethionate is used in men’s grooming products, such as face washes and shaving cleansers.
It improves foam quality and lubrication.
This supports smooth application.

In intimate hygiene products, it is chosen for its low irritation and compatibility with skin pH.
Sodium Lauroyl Isethionate helps maintain delicate balance.
This ensures safe cleansing.

Sodium Lauroyl Isethionate is used in luxury and premium cosmetic formulations to create rich, creamy textures.
It enhances sensory properties.
This increases product appeal.

Sodium Lauroyl Isethionate is applied in eco-friendly and biodegradable formulations as a sulfate-free surfactant.
It aligns with sustainable product trends.
This supports green chemistry.

In makeup removal and cleansing systems, it helps emulsify oils and residues.
Sodium Lauroyl Isethionate provides effective yet gentle cleansing.
This improves product performance.

Sodium Lauroyl Isethionate is also used in frequent-use hygiene products, such as daily hand washes.
It minimizes irritation from repeated use.
Sodium Lauroyl Isethionate is used wherever mild, sulfate-free cleansing with rich foam and skin compatibility is required, especially in advanced, sensitive-skin, and eco-conscious personal-care formulations.

Safety Profile:
Sodium Lauroyl Isethionate is generally considered to have low hazard potential, especially compared to harsher anionic surfactants such as sulfates.
Sodium Lauroyl Isethionate is widely used in personal-care products due to its mildness.
However, concentrated material requires standard handling precautions.

Skin contact is typically low risk, but prolonged exposure to concentrated powder or paste may cause mild irritation or dryness.
Sensitive individuals may experience slight redness.
Protective gloves are recommended in industrial handling.

Eye contact may cause mild to moderate irritation.
Symptoms can include redness, watering, and discomfort.
Eyes should be rinsed thoroughly with water if exposure occurs.

Inhalation of dust (for powdered forms) may cause respiratory irritation.
Symptoms can include coughing or throat irritation.
Adequate ventilation and dust control are important.

Ingestion is considered low toxicity, but large amounts may cause gastrointestinal discomfort.
Sodium Lauroyl Isethionate is not intended for oral consumption.
Medical advice should be sought if necessary.

Sodium Lauroyl Isethionate is not highly flammable, but like many organic solids, it can burn under high heat.
Fine particles may present a dust explosion risk in industrial environments.
Proper dust management is required.

The compound is chemically stable under normal conditions, but should be stored in a dry, sealed container to avoid moisture absorption.
Proper storage ensures product quality.
Sodium Lauroyl Isethionate should be kept away from strong oxidizing agents.

From an environmental perspective, Sodium Lauroyl Isethionate is biodegradable and relatively low in toxicity, but high concentrations may affect aquatic systems due to surfactant activity.
Spills should be controlled and disposed of properly.

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