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SODIUM LAURYL SULFATE


Sodium lauryl sulfate powder (SLS) or sodium Laureth sulfate (SLS), sometimes written sodium laurilsulfate, is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. Sodium Lauryl Sulfate (SLS), also known as Sodium Dodecyl Sulfate, is a synthetic organic compound found in many types of personal care and cleaning products.
SLS is produced by treating lauryl alcohol with sulfur trioxide gas to form the sulfate.


CAS NO: 151-21-3
EC NUMBER: 205-788-1

IUPAC NAMES: 
Dodecyl sodium sulfate
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
Dodecyl sulfate sodium salt
dodecyl sulphate sodium salt
dodecylbenzenesulfonate sodium
Dodecylsulfate, Sodium salt
Dosium lauryl sulfate
LAURYL SULFATE, SODIUM SALT
Natriumdodecylsulfat
Natriumlaurylsulfat
Schwefelsäuredodecylester
SDS, sodium lauryl sulfate, sodium laurilsulfate
Sodium Dodecyl Sulfate
Sodium dodecyl sulfate
sodium dodecyl sulfate
sodium dodecyl sulfate
Sodium dodecyl sulfate solution
SODIUM DODECYL SULPHATE
Sodium dodecyl sulphate
sodium dodecyl sulphate
Sodium Dodecyl Sulphate
Sodium dodecyl sulphate
Sodium dodecyl sulphate 
Sodium dodecylsulphate
Sodium lauryl sulfate
Sodium lauryl sulfate
sodium lauryl sulphate
Sodium laurylsulfuricum
Sodium n-dodecyl sulfate
sodium;dodecyl sulfate
Sulfuric acid monododecyl ester sodium salt


SYNONYMS: 
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, SLS, Sodium lauryl sulfate;Sodium monododecyl sulfate, powder; Sodium lauryl sulfate; Sodium monolauryl sulfate; Sodium dodecanesulfate; Sodium coco-sulfate; dodecyl alcohol, hydrogen sulfate, sodium salt; n-dodecyl sulfate sodium; Sulfuric acid monododecyl ester sodium salt; SDS; Sodium laureth sulfate; Sodium myreth sulfate; Ammonium lauryl sulfate; Potassium lauryl sulfate; SLS; Sodyum dodesil sülfat; 151-21-3; SODIUM LAURYL SULFATE; Sodium dodecylsulfate; Sodium lauryl sulphate; Sodium dodecyl sulphate; SODIUM DODECYL SULFATE; Dodecyl sodium sulfate; SODIUM DODECYL SULPHATE; Anticerumen; Gardinol; Neutrazyme; Duponal; Irium; Stepanol methyl; Stepanol wac; Stepanol waq; Perlandrol L; Perlankrol L; Standapol wa-ac; Stepanol me dry; Dodecyl sulfate sodium salt, powder; Sintapon L; Finasol osr2; Standapol WAQ; Stepanol WA; Incronol SLS; Maprobix NEU; Duponol QC; Duponol WA dry; Melanol CL; Dupanol WAQ; Duponol WAQE; Hexamol SLS; Dodecyl sulfate, sodium salt; Natriumlaurylsulfat; Sulfuric acid monododecyl ester sodium salt; Sipex SP; Sipex UB; Sodium n-dodecyl sulfate; Sterling WAQ-CH; Stepanol WA Paste; Avirol 118 conc; Duponol; Lauyl sodium sulfate; Stepanol T 28; Dreft; Aquarex methyl; Duponol methyl; Solsol needles; Steinapol NLS 90; Duponol waqa; Empicol LX 28; Melanol CL 30; NALS; Standapol waq special; Standapol was 100; Duponol qx; Jordanol SL-300; Richonol af; Stepanol WA-100; Finasol osr(sub 2); Standapol 112 conc; Stepanol ME Dry AW; Dodecyl sulfate sodium; Perklankrol ESD 60; SLS; Sipex sb; Sipex sd; Caswell No. 779; Duponol Me; Monagen Y 100; Richonol A; Richonol C; Duponol C; Maprofix LK; Stepanol ME; Akyposal SDS; Carsonol SLS; Maprofix NEU; Maprofix WAC; Stepanol methyl dry aw; Aquarex ME; Duponol WA; Duponol WAQ; Empicol LPZ; Natrium laurylsulfuricum; Berol 452; Duponal WAQE; Duponol WAQM; Lanette Wax-S; Sterling wa paste;; Conco sulfate WA; SODIUM LAURYL SULFATE (POWDER); Conco sulfate WN; EMAL O; Nikkol SLS; Orvus WA Paste; Sipex OP; Sipon LS; Sipon PD; Sipon WD; Detergent 66; Montopol La Paste; Sipon LS 100; Sipon LSB; Maprofix WAC-LA; Sodium monolauryl sulfate; Cycloryl 21; Sodyum dodesil sülfat; Cycloryl 31; Conco Sulfate WAG; Conco Sulfate WAN; Conco Sulfate WAS; Quolac EX-UB; Monododecyl sodium sulfate; Sodyum dodesil sülfat; Odoripon Al 95; Sodium monododecyl sulfate; Sodiumlauryl ether sulfate; Cycloryl 580; Cycloryl 585N; Lauryl sulfate sodium salt; Maprofix 563; Sinnopon LS 95; Laurylsiran sodny [Czech]; Empicol LS 30; Lauryl sodium sulfate; SLS; Rewopol NLS 30; Sinnopon LS 100; Carsonol SLS Special; SODIUM DODECYL SULPHATE; Dehydag sulfate GL emulsion; Lauryl sulfate, sodium salt; Avirol 101; Dehydrag sulfate gl emulsion; Dehydag sulphate GL emulsion; Emersal 6400; Monogen Y 100; Carsonol SLS Paste B; Emal 10; n-Dodecyl sulfate sodium; Conco sulfate WA-1200; Conco sulfate WA-1245; Product no. 75; Sodium lauryl sulfate ether; Sodium lauryl sulfate 30%; Product no. 161; Emulsifier no. 104; Sodium Laurylsulfate; CCRIS 6272; UNII-368GB5141J; HSDB 1315; P and G Emulsifier 104; NCI-C50191; Sodium lauryl sulfate, dental grade; Dodecyl alcohol, hydrogen sulfate, sodium salt; EINECS 205-788-1; EPA Pesticide Chemical Code 079011; NSC 402488; Sulfuric acid monododecyl ester sodium salt (1:1); SLS; CP 75424; Texapon K 1296; AI3-00356; CHEBI:8984; Laurylsulfuric Acid Sodium Salt; Dodecylsulfuric Acid Sodium Salt; 368GB5141J; NCGC00091020-03; DSSTox_CID_6031; DSSTox_RID_77989; DSSTox_GSID_26031; Sodium monododecyl sulfate; Sodium lauryl sulfate; Sodium monolauryl sulfate;; Sodium dodecanesulfate; Sodium coco-sulfate; dodecyl alcohol, hydrogen sulfate, sodium salt; n-dodecyl sulfate sodium; Sulfuric acid monododecyl ester sodium salt; SDS; Sodium laureth sulfate; Sodium myreth sulfate; SLS; Ammonium lauryl sulfate; Potassium lauryl sulfate; Sodyum dodesil sülfat; 151-21-3; SODIUM LAURYL SULFATE; Sodium dodecylsulfate; Sodium lauryl sulphate; Sodium dodecyl sulphate; Dodecyl sodium sulfate; SODIUM LAURYL SULFATE (POWDER); Anticerumen; Gardinol; Neutrazyme dodecyl hydroxysulfonate, sodium salt; ; Laurylsiran sodny; Rhodapon UB; sodiumdodecylsulfate; CAS-151-21-3; Dodecyl sulfate, sodium salt, 85%, pure; Lauryl sulfate sodium; NSC-402488; Dodecyl sulfate, sodium salt, 99%, for biochemistry; Empicol; sodium lauryl; Sodyum dodesil sülfat; Sodium lauryl sulfate powder [JAN:NF]; Dodecyl sulfate, sodium salt, 99+%, for molecular biology, DNAse, RNAse and Protease free; Dodecyl sulfate, sodium salt, pure, granular, spec. acc. the requirements of Ph.Eur.; sodiumlauryl sulfate; Sodium laurilsulfate; Sodium Lauryl Sulfate [USAN:JAN]; sodium dodecylsulphate; odium dodecyl sulphate; Sodium dedecyl sulfate; Sodium-dodecyl-S-SDS; IPC-SDS; ACMC-1BXOT; sodium n-dodecyl sulphate; Sodium Lauryl Sulfate NF; lauryl sulphate sodium salt; EC 205-788-1; dodecyl sulphate sodium salt; SCHEMBL1102; C12H25NaO4S;  (sds); KSC174S7B; n-Dodecyl sulfate sodium salt; ARONIS27060; CHEMBL23393; , 99%; sodium dodecyl sulphate (sds); ; ; SODIUM DODECYL SULPHATE; Sodium dodecyl sulphate solution; DTXSID1026031; ; Sodyum dodesil sülfat; SLS; dodecyl sulfuric acid sodium salt; KS-00000VTL; Dodecyl sulphuric acid sodium salt; Sodyum dodesil sülfat; Sodium lauryl sulfate (JP17/NF); BCP30594; ANW-21329; LS-880; SBB060993; AKOS015897278; AKOS025147308; Tox21_111059_1; DB00815; Dodecyl sulfuric acid ester sodium salt; NE10918; KS-000048K2; Lauryl Sulfate, powder, Sodium Salt (25% Aq.); D1403; FT-0603358; FT-0700721; I0352; Peg-(1-4)lauryl ether sulfate, sodium salt; , 10% solution in water;  BIOTECH GRD 100G; Sodium dodecylsulfate;Sodium lauryl sulphate;Dodecyl sodium sulfate; Sodyum dodesil sülfat; Dodecyl sulfate, sodium salt, 98%, for biochemistry, suitable for electrophoresis; Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

PRODUCT DETAILS & INFORMATION
Sodium Lauryl Sulfate (SLS), also known as Sodium Dodecyl Sulfate, is a synthetic organic compound found in many types of personal care and cleaning products.
Sodium Lauryl Sulfate (SLS) is produced by treating lauryl alcohol with sulfur trioxide gas to form the sulfate.
Sodium Lauryl Sulfate may be used in pure form or extracted from palm kernel or coconut oil via a process known as hydrolysis, which is a chemical breakdown that occurs as the result of a reaction with water.
This is followed by hydrogenation, which is the addition of hydrogen to achieve saturation.
According to the Sodium Lauryl Sulfate MSDS (Material Safety Data Sheet), the product contains no ingredients that pose a hazard to human health or the environment.

Sodium lauryl sulfate is a widely used surfactant in cleaning, cosmetics, and personal care products for its exceptional foaming and excellent viscosity building properties.
Sodium lauryl sulfate is a highly effective anionic surfactant used to remove oily stains and residues and exhibits a lower cold temperature cloud point than typical products of this type.

Sodium lauryl sulfate (SLS) is an anionic surfactant commonly used in detergents and cleaning products.
While widely used in pesticide formulations as a surfactant and dispersant, Sodium Lauryl Sulfate (SLS), is usually an inert ingredient or used in combination with other ingredients, most of which are ineligible for use in minimum-risk pesticides.
Sodium Lauryl Sulfate (SLS) has some antimicrobial activity but is more often a synergist used with other antimicrobial active ingredients.

Sodium Lauryl Sulfate, SLS (synonymously called Sodium dodecyl sulfate, SDS) [CH3 (CH2)11 OSO3 Na] (MW 288.38) is an anionic (negatively charged) surfactant used as a cleansing agent (detergent) in cosmetics.
It is prepared by the sulphation of commercially available lauryl alcohol from coconut oil.
The molecule has a tail of 12 carbon atoms, attached to a sulfate group, giving the molecule the amphiphilic properties required of a detergent.
This foaming detergent is cheap, used in personal care products and a small amount generates a large amount of foam.
Sodium Lauryl Sulfate (SLS) is used as a detergent in most (90%) of commercial soaps and shampoos.
Additionally, it is found in a large number of personal care products including toothpaste, body wash, cleansers, facial cleansers, bath oils, salts, bubbles, liquid hand soap, baby bath wash, hair removers, fragrance, perfume, cologne, sunscreen, tanning oil, conditioners, styling products and makeup removers.

USES & APPLICATIONS
The many industrial uses of Sodium Lauryl Sulfate include:
Personal Care: Lower concentrations of lauryl sulfate are used in a wide range of personal care products such as toothpaste, oral care, mouthwash, shaving cream and bubble bath.
Rubber: In rubber manufacturing applications, Sodium Lauryl Sulfate acts as a flow agent and internal lubricant.
CASE: Sodium Lauryl Sulfate (SLS) can act as an extremely effective wetting agent due to its ability to reduce the surface tension in various liquids.
Soaps and Detergents: Sodium Lauryl Sulfate will act as a surfactant in liquid soap and detergent, and it is also an excellent additive for compact powders.
Nutraceuticals: Manufacturers of nutraceuticals use Sodium Lauryl Sulfate as an excipient (inactive ingredient) in many of their products.

Its functions (INCI)
Cleansing: Helps to keep a clean surface
Denaturant: Makes cosmetics unpleasant. Mainly added to cosmetics containing ethyl alcohol
Emulsifying: Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
Foaming: Capturing small air bubbles or other gases in a small volume of liquid by changing the surface tension of the liquid
Surfactant: Reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used

Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil.
It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.
Sodium Lauryl Sulfate (SLS) lowers the surface tension of aqueous solutions and is used as a fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpaste.
It is also used in creams and pastes to properly disperse the ingredients and as a research tool in protein biochemistry. Sodium Lauryl Sulfate (SLS) also has some microbicidal activity.


Sodium Lauryl Sulfate, also known as SLS, is a surfactant that is widely used in many different types of consumer products.
These type of surfactants are commonly known as “foaming agents” and are used in products designed to clean including personal care and home cleaning products.
They work by lowering water surface tension to effectively spread a product across the surface being cleaned, attracting dirt and grime away from the surface and down the drain.


Sodium Lauryl Sulfate (SLS) is an anionic surfactant with superior viscosity and foaming properties and high detergency. It offers an advantage over ether sulfates in its easy rinsability off the skin. The product is used in a wide range of personal care products such as shampoos, liquid soaps, hand pastes, bath products, shaving creams etc.

Outstanding foaming characteristics and detergency of Sodium Lauryl Sulfate (SLS) are being utilized in the formulation of light-duty cleaners, rug shampoos, fine fabric wash, textile scouring and many other industrial applications such as emulsion polymerization, oil field chemicals, construction etc.


Application areas
HI&I cleaning
Emulsion polymerization
Fire-fighting
Personal care
Laundry detergents
Industrial auxiliaries
Construction chemicals
Oil fields


Applications Segment:
Industrial Cleaning
Household Cleaning
Polymerization
Pharmaceuticals
Others


Types Segment:
Sodium Lauryl Sulfate (SLS) Needle
Sodium Lauryl Sulfate (SLS) Powder
Sodium Lauryl Sulfate (SLS) Liquid


Production of Sodium Lauryl Sulfate (SLS) :
Sodium Lauryl Sulfate (SLS) is prepared by the sulfation of commercially available lauryl alcohol with either sulphur trioxide or chlorosulfonic acid.
The product of this reaction is then neutralised with aqueous sodium hydroxide or sodium carbonate.
Lauryl alcohol is in turn usually derived from either coconut oil or palm kernel oil by hydrolysis, which liberates their fatty acids, followed by hydrogenation.
Due to the synthetic method, commercial samples of Sodium Lauryl Sulfate (SLS) are often a mixture with other alkyl sulfates, dodecyl sulfate as the main component.

Sodium lauryl sulfate (SLS) is a chemical compound that is commonly used in personal care and cleaning products, such as body washes, detergents, cleansers, shampoos, handwashes and toothpaste. Sodium Lauryl Sulfate (SLS) is what’s known as a surfactant—that means it reduces the surface tension between ingredients in a product. It can be made synthetically or naturally, and it’s what gives cleaning products that foamy, bubbly consistency most of us have come to expect.

Like other surfactants, Sodium Lauryl Sulfate (SLS) is amphiphilic. It thus migrates to the surface of liquids, where its alignment and aggregation with other Sodium Lauryl Sulfate (SLS) molecules lowers the surface tension.
This allows for easier spreading and mixing of the liquid. Sodium Lauryl Sulfate (SLS) has potent protein denaturing activity and inhibits the infectivity of viruses by solubilizing the viral envelope and denaturing envelope and capsid proteins.

Versatile ingredient composed of several non-volatile alcohols. Functions primarily as a surfactant, but can also be used as a skin-conditioning agent, emulsifier, and solvent.

Sodium lauryl sulfate (SLS) is one of the most sensitizing cleansing agents used in skincare products.

Sodium Lauryl Sulfate (SLS) is a widely used ionic solubilizer & and high HLB anionic emulsifier that is suitable for application in liquid dispersions, solutions, emulsions and microemulsions to formulate tablets, foams and semi-solids such as creams, lotions and gels.

Sodium Lauryl Sulfate (SLS) is manufactured by sulfation of the corresponding fatty alcohol of natural origin and subsequent neutralization with sodium hydroxide.
Sodium Lauryl Sulfate (SLS) is characterized by a very high active substance matter and very low content of inorganic salts and unsulfated fatty alcohols.

Extremely efficient excipient throughout the tableting process
Widely used ionic solubilizer and high HLB anionic emulsifier
Additionally suitable as wetting agent or lubricant
Suitable for solid, semi-solid dosage forms and foams

Solubilizer and emulsifier
Sodium Lauryl Sulfate (SLS) can be used as a solubilizer to enhance the solubility of poorly soluble APIs in both solid and liquid oral dosage forms.
Sodium Lauryl Sulfate (SLS) grades are also suitable for semi-solid dosage forms like creams, lotions and gels. Moreover, sodium lauryl sulfate is very broadly used in oral care formulations.
Sodium Lauryl Sulfate (SLS) can be used in physical mixing, melt granulation, spray drying and hot-melt extrusion processes.
Sodium Lauryl Sulfate (SLS) is extremely efficient throughout the tabletting process by assisting in drug dissolution and aiding water uptake during the disintegration of the end formulation.


The wetting agent in tabletting
Due to the improved wettability of the tablet, Sodium Lauryl Sulfate (SLS) can reduce tablet disintegration time.


Special lubricant for tablets
Sodium Lauryl Sulfate (SLS) can be used as a tablet lubricant if standard lubricants (i.e. magnesium stearate) are incompatible with the formulation.
As lubricant, the typical usage concentration of Sodium Lauryl Sulfate (SLS) is 2%.

Sodium Lauryl Sulphate is a chemical surfactant used in all sorts of cosmetics and cleaning products. It can be derived from petroleum, palm oil or coconut oil.

It works by turning liquids into a foam and you’ll usually find it in things like toothpaste, body wash, soaps and detergents. It’s also an ingredient in industrial strength cleaners, bath salts and even make-up.


Sodium Lauryl Sulfate (SLS) Chemical Properties, Uses and Production

Anionic surfactants
Sodium Lauryl Sulfate (SLS) is an anionic surfactant and is a typical representative of sulphate-based surfactant.
It is abbreviated as SDS, and also known as AS, K12, coco alcohol sulfate, sodium lauryl sulfate and foaming agent.
The commercial products are usually white to light yellow crystalline powder. It is non-toxic, slightly soluble in alcohol, insoluble in chloroform and ether, soluble in water, and has good anionic and nonionic complex compatibility. It has good emulsibility, foamability, and foaming, infiltrating, decontaminating and dispersing properties. It is abundant in foams and quickly biodegradable, and has solubility next only to fatty alcohol polyoxyethylene ether sodium sulphate (abbreviated as AES). It is not sensitive to alkali and hard water, but its stability is inferior to general sulfonate under acidic conditions and is close to AES. It is not favorable to exceed 95 °C upon long-term heating, and its irritation is at the middle level among surfactants, with an irritation index of 3.3 for a 10% solution, which is higher than AES and lower than sodium dodecylbenzene sulfonate (abbreviated as LAS).
Toxicity LD50 is 1300mg/kg. There is no evidence that this product is carcinogenic, but high doses may indeed irritate the skin.
However, in general, sanitary products, the concentration is limited when used as a forming agent, and is in line with national standards.
So there is no need to concern.
Sodium Lauryl Sulfate (SLS) is a major component of detergent.
Sodium Lauryl Sulfate (SLS) is usually used in the DNA extraction process to separate DNA after protein denaturation.
Sodium Lauryl Sulfate (SLS) is widely used as a foaming agent in toothpaste, soap, shower gel, shampoo, detergent and cosmetics.
95% of personal care products and household cleaning products contain sodium lauryl sulfate.

Sodium Lauryl Sulfate (Sodium Lauryl Sulfate (SLS)) is a common additive used in a variety of personal care products including toothpastes, shampoos and body washes, and in a variety of household products including laundry detergents, floor cleaners and engine degreasers. Sodium Lauryl Sulfate (SLS), similar to soap, is used as a surfactant, detergent and emulsifier; in short, it is an inexpensive and effective foaming agent. Because many people associate foaming with effective cleaning, Sodium Lauryl Sulfate (SLS) is frequently added to cleaning and personal care products such as toothpaste.
Sodium Lauryl Sulfate is useful in a wide variety of personal care applications in which viscosity building and foam characteristics are of importance.
Because of its low salt content, this product is particularly useful in formulations that are sensitive to high levels of sodium chloride.
It is compatible with alkanolamides and amphoterics so that maximum optimization of foam and viscosity characteristics can be reached in the finished product.
It can be incorporated into shampoos, handsoaps, bath products, shaving creams and medicated ointments.
It is especially useful for opaque, pearlescent, or cream products.

Product advantages:

excellent cleaning and cleaning properties,
very high foam-forming capacity,
a wide range of cosmetic and industrial applications,
has an effect under both alkaline and acidic pH conditions.

Chemical property
It is a white to pale yellow powder, has a slight special smell, and is easily soluble in water.

Uses
Sodium Lauryl Sulfate (SLS) has excellent detergency, emulsification and foaming power, can be used as detergents and textile auxiliaries, and is also used as an anionic surfactant, toothpaste foaming agent, mine fire extinguishing agents, foaming agents for fire extinguishers, emulsion polymerization emulsifiers, emulsifying and dispersing agents for medical use, shampoo and other cosmetic products, wool detergent, detergent for silky class fine fabrics and flotation agent for metal beneficiation.
GB 2760-96 stipulates as processing aids for food industry. Sodium Lauryl Sulfate (SLS) used as foaming agents; emulsifying agents; and anionic surfactants. It is used for cakes, drinks, proteins, fruits, fruit juice, and edible oil, and so on.
Sodium Lauryl Sulfate (SLS) is used as surfactants, detergents, foaming agents, and wetting agents, and so on.
Sodium Lauryl Sulfate (SLS) is used as relatively low-level ion-pairing reagents, and is cheaper than sodium heptanesulfonate and sodium pentanesulfonate when less demanding.
Sodium Lauryl Sulfate (SLS) is used as raw material for modifying materials.
Sodium Lauryl Sulfate (SLS) is used as additives in capillary electrophoresis analysis and is generally used as molar solution.
Sodium Lauryl Sulfate (SLS) is also used in other analysis such as flow column analysis.

Production method
Sulphur trioxide method: the reaction apparatus is a vertical reactor. At 32 °C nitrogen gas is introduced into the reactor through the gas vents at a flow rate of 85.9 L·min-1. At 82.7 kPa lauryl alcohol is introduced at a flow rate of 58 g·min-1. The liquid sulfur trioxide is fed into a flash evaporator at 124.1 kPa, the flash temperature is maintained at 100 °C, and the sulfur trioxide flow rate is controlled to be 0.907 2 kg·h-1. The sulfated product is then rapidly quenched to 50 °C, injected into the ageing device and left for 10 to 20 min, and finally injected into the neutralization kettle and neutralized with a base. The neutralizing temperature is controlled at 50 °C. The material is discharged when the pH value is adjusted to 7 to 8.5, to obtain a liquid product which is spray dried to give a solid product.
Batch method: lauryl alcohol is charged into the reaction kettle and pre-heated to 30 °C. Then chlorosulfonic acid 0.03 mol in excess than the theoretical amount is sprayed into the alcohol under high-speed agitation. The reaction temperature was controlled at 30 to 35 °C. After the sulfation reaction, it is injected into the neutralization kettle and neutralized with 30% lye to a pH value of 7 to 8.5, and finally bleached with 0.4% (weight) hydrogen peroxide. It is spray dried to give a solid. It can also be formulated into solutions according to a quality standard.
Continuous method: the reaction apparatus is the tubular reactor. Lauryl alcohol is initially saturated with hydrogen chloride. Lauryl alcohol at a flow rate of 334 g·min-1 and hydrogen chloride at a flow rate of 40.5 g·min-1 are fed into the saturation chamber through a gauge. Then the solution of lauryl alcohol with hydrogen chloride is fed into the reactor at 21.4 °C to react with chlorosulfonic acid. After the reaction is subjected to gas-liquid separation, the sulfated product flows from the bottom of the separator into a neutralization kettle. It is neutralized with 30% sodium hydroxide at 50 °C to give a liquid product, which is spray-dried to give a solid product.

Chemical Properties
White crystalline flakes

Chemical Properties
Sodium lauryl sulfate consists of white or cream to pale yellow colored crystals, flakes, or powder having a smooth feel, a soapy, bitter taste, and a faint odour of fatty substances.

Uses
Sodium Lauryl Sulfate (SLS) is an emulsifier and whipping aid that has a solubility of 1 g in 10 ml of water. It functions as an emulsifier in egg whites. It is used as a whipping aid in marshmallows and angel food cake mix. It also functions to aid in dissolving fumaric acid.
Anionic detergent
hydrophilic tablet lubricant


Wetting agent, detergent, especially in the textile industry. Electrophoretic separation of proteins and lipids. Foaming agent and detergent for cosmetics and pharmaceuticals, Wetting agent for wettable powders
Foaming agent and booster of tooth pastes and shampoos.
Emulsifier for polymerization process of synthetic rubber and synthetic resin
Shampoos and body shampoos, hard surface liquid detergents and laundry product
Can be added to formulas as is. Recommended use level 3 - 30% depending on desired foaming and cleansing effects. Can be used at higher concentrations for bubble baths. For external use only.

Benefits:
An excellent foam and viscosity enhancer
Good cleansing properties
Can be used together with other surfactants
Provides high foam, good lather, and excellent detergent properties


Applications:
Body washes, shampoos, bubble baths, cleansing lotions, various personal care cleansing products.
All-purpose cleaners
Bath oils
Detergents
Dishwash detergents
Emulsion polymerization
Exfoliant scrub
Glass cleaners
Green products
Hand soap
Rug shampoo

Raw material source: Coconut oil and chlorosulfuric acid
Manufacture: 
Sodium lauryl sulfate is produced by treating lauryl alcohol, which is derived from either coconut or other vegetable oils, with chlorosulfuric acid. The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate.

Definition
An anionic surfactant, usually a mixture of sodium alkyl sulfates that lowers surface tension of aqueous solutions.

Production Methods
Sodium lauryl sulfate is prepared by sulfation of lauryl alcohol, followed by neutralization with sodium carbonate.

General Description
White to pale yellow paste or liquid with a mild odor. Sinks and mixes with water.

Air & Water Reactions
Insoluble in water.


Incompatibilities
Sodium lauryl sulfate reacts with cationic surfactants, causing loss of activity even in concentrations too low to cause precipitation. Unlike soaps, it is compatible with dilute acids and calcium and magnesium ions.
Sodium lauryl sulfate is incompatible with salts of polyvalent metal ions, such as aluminium, lead, tin or zinc, and precipitates with potassium salts. Solutions of sodium lauryl sulfate (pH 9.5–10.0) are mildly corrosive to mild steel, copper, brass, bronze, and aluminium.

Regulatory Status
GRAS listed. Included in the FDA Inactive Ingredients Database (dental preparations; oral capsules, suspensions, and tablets; topical and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.


Raw materials
Metering vessel 1-Dodecanol Hexane Liquid sulfur trioxide Ethanol Hydrogen peroxide Sulfur trioxide Chlorosulfonic acid Hydrochloric acid DCM Sodium hydroxide SULFATE STANDARD Poly(acrylic acid)

sodium lauryl sulfate is a synthetic organic compound with the formula CH3(CH2)11SO4Na.
It is an anionic surfactant used in many cleaning and hygiene products.
This molecule is an organosulfur and a salt.
It consists of a 12-carbon tail attached to a sulfate group, that is, it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid.
Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.
Also derived as a component of mixtures produced from inexpensive coconut and palm oils, Sodium Lauryl Sulfate (SLS) is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations

TYPE OF INGREDIENT: Foaming agent.
MAIN BENEFITS: Sodium Lauryl Sulfate (SLS) creates a lather, Sodium Lauryl Sulfate (SLS) Encourages a deep clean, and Sodium Lauryl Sulfate (SLS) Emulsifies.


Sodium lauryl sulfate is frequently used as a surfactant or foaming agent. It may also serve as an emulsifier, helping oil-based and water-based ingredients to stay mixed.
In many of our toothpastes, Sodium Lauryl Sulfate (SLS) is used as a surfactant and helps to properly disperse the ingredients during brushing, and ensures easy rinsing and removal of debris

Sodium lauryl sulfate (SLS) is a surfactant that can have a variety of uses, but in cleaning products, it is often used to break water tension and attract dirt and grime away from the material it is intended to clean. We use Sodium Lauryl Sulfate (SLS) that is derived from coconut or palm kernel oil from renewable carbon plant-derived materials.


Sodium lauryl sulfate may be derived from either petroleum-based or vegetable-based sources.
The Sodium Lauryl Sulfate (SLS) is entirely derived from the vegetable sources of coconut and/or palm kernel oil.
The oils can be split into glycerin and the component fatty acids, one of which is lauric acid.
The lauric acid is isolated and then hydrogenated to form the lauryl alcohol.
Alternately, the whole oil can be esterified and then hydrogenated to form the fatty alcohols of which lauryl alcohol would be isolated by fractionation.
The lauryl alcohol is then combined with sulfur which then forms the salt, sodium lauryl sulfate.

Physicochemical properties
Bottle of 20% Sodium Lauryl Sulfate (SLS) in distilled water for use in the laboratory.
The critical micelle concentration (CMC) in pure water at 25 °C is 8.2 mM, and the aggregation number at this concentration is usually considered to be about 62.
The micelle ionization fraction (α) is around 0.3 (or 30%).

Production
Sodium lauryl sulfate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.
The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate.
Lauryl alcohol can be used in pure form or may be derived from either coconut or palm kernel oil by hydrolysis (which liberates their fatty acids), followed by hydrogenation.
When produced from these sources, commercial samples of these "Sodium lauryl sulfate" products are actually not pure Sodium Lauryl Sulfate (SLS), rather a mixture of various sodium alkyl sulfates with Sodium lauryl sulfate being the main component.
For instance, Sodium Lauryl Sulfate (SLS) is a component, along with other chain-length amphiphiles, when produced from coconut oil, and is known as sodium coco sulfate (SCS).
Sodium lauryl sulfate is available commercially in powder, pellet, and other forms (each differing in rates of dissolution), as well as in aqueous solutions of varying concentrations.


Applications:
Cleaning and hygiene
Sodium lauryl sulfate is mainly used in detergents for laundry with many cleaning applications.
It is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues.
For example, it is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car exterior cleaners.

In lower concentrations, it is found in hand soap, toothpastes, shampoos, shaving creams, and bubble bath formulations, for its ability to create a foam (lather), for its surfactant properties, and in part for its thickening effect.

Food additive

This section needs expansion with: a secondary source-derived summary of its uses in food and related products, as this is a clear more preeminent application than many of those that follow.

Sodium Lauryl Sulfate (SLS), appearing as its synonym sodium lauryl sulfate (SLS), is considered generally recognized as a safe (GRAS) ingredient for food use according to the USFDA.
It is used as an emulsifying agent and whipping aid.
Sodium Lauryl Sulfate (SLS) is reported to temporarily diminish the perception of sweetness.

Denaturation of a protein using Sodium Lauryl Sulfate (SLS)
In the case of SDS-PAGE, the compound works by disrupting non-covalent bonds in the proteins, and so denaturing them, i.e. causing the protein molecules to lose their native conformations and shapes. By binding to proteins at a ratio of one Sodium Lauryl Sulfate (SLS) molecule per 2 amino acid residues, the negatively charged detergent provides all proteins with a similar net negative charge and therefore a similar charge-to-mass ratio.
In this way, the difference in mobility of the polypeptide chains in the gel can be attributed solely to their length as opposed to both their native charge and shape.
It is possible to make separation based on the size of the polypeptide chain to simplify the analysis of protein molecules, this can be achieved by denaturing proteins with the detergent Sodium Lauryl Sulfate (SLS).
The association of Sodium Lauryl Sulfate (SLS) molecules with protein molecules imparts an associated negative charge to the molecular aggregate formed; this negative charge is significantly greater than the original charge of that protein.
The electrostatic repulsion that is created by Sodium Lauryl Sulfate (SLS) binding forces proteins into a rod-like shape, thereby eliminating differences in shape as a factor for electrophoretic separation in gels.
A dodecyl sulfate molecule has two negative charges at the pH value used for electrophoresis, this will lead the net charge of coated polypeptide chains to be much more negative than uncoated chains. The charge-to-mass ratio is essentially identical for different proteins because Sodium Lauryl Sulfate (SLS) coating dominates the charge.


Sodium lauryl sulfate is widely used in the pharmaceutical field as an ionic solubilizer and emulsifier that is suitable for applications in liquid dispersions, solutions, emulsions and microemulsions, tablets, foams and semi-solids such as creams, lotions and gels.
Additionally, Sodium Lauryl Sulfate (SLS) aids in tablet wettability, as well as lubrication during manufacturing.


Miscellaneous applications:
Sodium Lauryl Sulfate (SLS) is used in an improved technique for preparing brain tissues for study by optical microscopy. The technique, which has been branded as CLARITY, was the work of Karl Deisseroth and coworkers at Stanford University, and involves infusion of the organ with an acrylamide solution to bind the macromolecules of the organ (proteins, nucleic acids, etc.), followed by thermal polymerization to form a "brain–hydrogel" (a mesh interspersed throughout the tissue to fix the macromolecules and other structures in space), and then by lipid removal using Sodium Lauryl Sulfate (SLS) to eliminate light scattering with minimal protein loss, rendering the tissue quasi-transparent.

Along with sodium dodecylbenzene sulfonate and Triton X-100, aqueous solutions of Sodium Lauryl Sulfate (SLS) are popular for dispersing or suspending nanotubes, such as carbon nanotubes.

Liquid membranes formed from Sodium Lauryl Sulfate (SLS) in water have been demonstrated to work as unusual particle separators.
The device acts as a reverse filter, allowing large particles to pass while capturing smaller particles.

Sodium lauryl sulfate (SLS) is the sodium salt of lauryl sulfate. It typically appears as a white or cream-coloured crystal or powder. It may also be called sodium dodecyl sulfate; dodecyl sulfate, sodium salt; and sodium n-dodecyl sulfate.

It’s inexpensive and can be derived from a number of sources including petroleum, coconut oil, and even palm oil.

Sodium Lauryl Sulfate
Sodium lauryl sulfate (SLS), a cleaning agent and surfactant, is an ingredient in much personal care and cleaning products.
Sodium Lauryl Sulfate (SLS) can be derived from natural sources like coconut and palm kernel oil and can also be manufactured in a laboratory setting.

Uses & Benefits
Personal Care Products
Sodium Lauryl Sulfate (SLS) has been an ingredient in shampoos since the 1930s. It works as a surfactant, trapping oil and dirt in the hair so it can rinse away with water.
An effective foaming agent, Sodium Lauryl Sulfate (SLS) can help create a rich lather in products like body and hand wash, facial cleansers and bubble.
Likewise, Sodium Lauryl Sulfate (SLS) helps create the foaming action in toothpaste and also helps remove food particles from teeth.


Cleaning Products
Sodium Lauryl Sulfate (SLS) is an effective surfactant used in household cleaning products to help remove oily stains and residues, such as food stains in carpets.
Because of its ability to break down oil and grease, Sodium Lauryl Sulfate (SLS) also is an ingredient in many industrial cleaning products, such as engine degreasers and industrial strength detergents.

Sodium Lauryl Sulfate (SLS) is available commercially in powder and pellet forms.
The salt is a 12-carbon chain attached to a sulfate group giving the material the amphiphilic properties required of a detergent.
Sodium coco sulfate is essentially the same compound but made from less purified coconut oil.
A related surfactant, Sodium Laureth Sulfate (SLES) is more widely used as a detergent and surfactant in personal care products (soaps, shampoos, toothpaste etc.) and in some medicated shampoos.
SLES is effective over a wide pH range, both in acidic and alkaline solution and in hard water (because of the solubility of the corresponding calcium and magnesium salts i.e. no common ion effect).
It differs from Sodium Lauryl Sulfate (SLS) by virtue of the presence of ethoxyl groups [(OCH2CH2)n] in the backbone where n=3 or more, which is thought to give SLES extra foaming activity.
Triethanolamine lauryl sulphate is also occasionally used in medicated shampoos.

Use
Concentration Skin cleanser in topical applications 1% w/v
Tablet lubricant (for dispersible tablets) 0.5–2% w/w
Wetting agent in dentifrices (toothpastes) 1–2% w/w
Releasing agent in suppositories and pessaries 0.4–1% w/w
Dissolution / wetting agent in solid oral dosage forms 0.2–1.5% w/w
Foaming / lathering agent in shampoos 10–25% w/v
 

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