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In personal care and cosmetics, Sodium Linoleate is used as an emulsifier, surfactant, cleansing agent, and viscosity controller in lotions, creams, soaps, shampoos and oil-based formulations.
Sodium Linoleate helps to blend oil and water phases, stabilize emulsions, and condition the skin due to its fatty acid origin that can support moisture retention.
In industrial and laboratory contexts, sodium linoleate is used as a surfactant precursor, stabilizer and research reagent in lipid chemistry.
CAS Number: 822-17-3
EC Number: 212-491-0
MDL Number: MFCD00063202
Molecular Formula: C18H31NaO2
Molecular Weight: 302.43
SYNONYMS:
Sodium linoleate,Sodium (9Z,12Z)-octadeca-9,12-dienoate,Linoleic acid, sodium salt,PRISAVON L,872C9A1W9I,EINECS 212-491-0,9,12-Octadecadienoic acid (Z,Z)-, sodium salt,9,12-Octadecadienoic acid (9Z,12Z)-, sodium salt,DTXSID5041562,9,12-Octadecadienoic acid (9Z,12Z)-, sodium salt (1:1),9,12-OCTADECADIENOIC ACID, SODIUM SALT,RefChem:887660,SODIUM LINOLEATE [INCI],DTXCID3021562,Linoleic acid sodium salt,822-17-3,Sodium linolate,sodium,(9Z,12Z)-octadeca-9,12-dienoate,Linoleic Acid (sodium salt), MFCD00063202, C18H31NaO2, UNII-872C9A1W9I, SCHEMBL107358, CHEMBL571449, WYPBVHPKMJYUEO-NBTZWHCOSA-M, EBC-75061, CS-W012114, HY-W011398, AC-33772, FS159638, SY110510, Linoleic acid sodium salt, >=98% (GC),Sodium(9Z,12Z)-octadeca-9,12-dienoate, L0056,NS00079542, cis-9,cis-12-Octadecadienoic acid sodium salt, A916196,9,12-Octadecadienoic acid (9Z, 12Z)-, sodium salt,Q27269782,linoleic acid sodium salt,linoleic acid, sodium salt,(9Z,12Z)-9,12-octadecadienoic acid sodium salt,cis-9,cis-12-octadecadienoic acid sodium salt,9,12-octadecadienoic acid, sodium salt, (9Z,12Z)- (1:1),sodium (9Z,12Z)-9,12-octadecadienoate,sodium (9Z,12Z)-octadeca-9,12-dienoate,sodium,(9Z,12Z)-octadeca-9,12-dienoate,Linoleic acid, sodium salt, Sodium linoleate, Sodium linolate, 9,12-Octadecadienoic acid (9Z,12Z)-, sodium salt, 9,12-Octadecadienoic acid (Z,Z)-, sodium salt,Linoleic acid sodium salt, cis-9,cis-12-octadecadienoic acid sodium salt, sodium linolate, (9Z,12Z)-9,12-octadecadienoic acid sodium salt, sodium (9Z,12Z)-octadeca-9,12-dienoate, linoleic acid sodium, sodium linoleic acid,9,12-Octadecadienoic acid (9Z,12Z)-,sodium salt (1:1),Linoleic acid,sodium salt, 9,12-Octadecadienoic acid (Z,Z)-,sodium salt,9,12-Octadecadienoic acid (9Z,12Z)-,sodium salt,Sodium linoleate,Sodium linolate, SODIUM LINOLEATE, SodiumLinoleate>Linoleate (sodium ), linoleic acid sodium, LINOLEIC ACID SODIUM SALT ,sodium (9Z,12Z)-octadeca-9,12-dienoate,12-octadecadienoicacid(z,z)-sodiumsalt, SODIUM (9E,12E)-OCTADECA-9,12-DIENOATE, (Z,Z)-9,12-Octadecadienoic acid sodium salt, LINOLEIC ACID SODIUM SALT ISO 9001：2015 REACH,Sodium linolate, Sodium linoleate, cis-9,cis-12-Octadecadienoic acid sodium salt
Sodium Linoleate is a sodium salt of Linoleic Acid (q.v.).
Sodium linoleate is the sodium salt of linoleic acid, a polyunsaturated fatty acid.
Sodium Linoleate typically appears as a white to off-white powder or flakes and is soluble in water, forming a stable solution.
Sodium Linoleate is characterized by its amphiphilic nature, possessing both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, which makes it an effective surfactant and emulsifier.
Sodium linoleate is a versatile compound recognized for its significant role in various industrial and research applications.
USES and APPLICATIONS of SODIUM LINOLEATE:
Sodium Linoleate can be used for cell culture materials, fluidic device module, drug testing, and fluidic device.
Sodium linoleate serves multiple functions across industries.
In personal care and cosmetics, Sodium Linoleate is used as an emulsifier, surfactant, cleansing agent, and viscosity controller in lotions, creams, soaps, shampoos and oil-based formulations.
Sodium Linoleate helps to blend oil and water phases, stabilize emulsions, and condition the skin due to its fatty acid origin that can support moisture retention.
In industrial and laboratory contexts, sodium linoleate is used as a surfactant precursor, stabilizer and research reagent in lipid chemistry.
Its role as a model compound in fatty acid metabolism studies and in synthesis of biodegradable surfactants positions Sodium Linoleate in biochemical and biotechnological research.
Additionally, Sodium Linoleate may be used in animal nutrition and feed formulations to modify lipid profiles in livestock diets.
Because sodium linoleate is fundamentally a salt of an essential fatty acid (linoleic acid), it benefits from the physiological relevance of linoleic acid, which is a key omega-6 fatty acid precursor in mammalian metabolism and contributes to cell membrane structure and signaling pathways.
Cosmetic Uses of Sodium Linoleate: cleansing agents, surfactants,
surfactant - emulsifying, viscosity-controlling agents.
Sodium linoleate is commonly used in various applications, including cosmetics, food products, and pharmaceuticals, due to its ability to stabilize emulsions and enhance texture.
Additionally, Sodium Linoleate has potential health benefits, as linoleic acid is an essential fatty acid that plays a crucial role in human nutrition.
Sodium Linoleate is also known for its antioxidant properties, which can help protect cells from oxidative stress.
However, like many substances, Sodium Linoleate should be handled with care, as it may cause irritation in some individuals.
Overall, sodium linoleate is valued for its functional properties in both industrial and health-related applications.
This sodium salt of linoleic acid, Sodium Linoleate, is commonly utilized in the formulation of emulsifiers, surfactants, and stabilizers, making it invaluable in the food, cosmetic, and pharmaceutical industries.
Its unique properties allow Sodium Linoleate to enhance the texture and stability of products, providing a smooth and consistent feel in creams and lotions.
Additionally, sodium linoleate is known for its skin-conditioning benefits, making it a popular ingredient in personal care formulations aimed at moisturizing and nourishing the skin.
In research settings, sodium linoleate serves as a model compound for studying fatty acid metabolism and its effects on cell signaling pathways.
Sodium Linoleate's application extends to the production of biodegradable surfactants, aligning with the growing demand for sustainable and eco-friendly alternatives in various sectors.
With its multifunctional properties and broad applicability, sodium linoleate stands out as a key ingredient for professionals seeking effective solutions in formulation and research.
Sodium Linoleate is a precursor to arachidonic acid and other prostaglandins
Sodium Linoleate is a compound used in various research disciplines, including nutrition science, biochemistry, and cell biology.
In nutrition research, Sodium Linoleate serves as a model to study the role of fatty acids in the human diet, particularly as linoleic acid is an essential omega-6 fatty acid.
Biochemists investigate the incorporation of Sodium Linoleate into cell membranes and its effect on membrane fluidity and function.
Moreover, Sodium Linoleate is instrumental in examining the enzymatic pathways of lipid metabolism, as well as the production of eicosanoids, which are signaling molecules that play a key role in inflammation and immunity.
In cell culture studies, Sodium Linoleate is added to media to assess its influence on cell growth and differentiation.
Additionally, Sodium Linoleate is used in the development of lipid-based chemical delivery systems, where the salt form enhances the solubility of lipophilic compounds.
BENEFITS IN FORMULATIONS of SODIUM LINOLEATE:
Sodium linoleate’s benefits in product formulation include moisturizing and skin-conditioning properties due to its fatty acid backbone, along with functional performance as a surfactant, emulsifier and viscosity agent.
In personal care products, Sodium Linoleate can improve texture, help maintain skin hydration and contribute to stable oil-in-water systems.
Sodium Linoleate's biodegradable nature and derivation from natural fatty acids align with trends toward sustainability and mildness in consumer and industrial products.
FUNCTIONS of SODIUM LINOLEATE:
*Cleansing Agent,
*Emulsifier,
*Viscosity Controlling
FUNCTIONAL CHARACTERISTICS of SODIUM LINOLEATE:
As a sodium salt of an unsaturated fatty acid, sodium linoleate lowers surface tension at interfaces, enabling emulsification and detergency in aqueous media.
Sodium Linoleate can help disperse oils in water, stabilize fine mixtures of immiscible phases, and contribute to foaming and wetting behavior in formulations.
In aqueous solutions, Sodium Linoleate's anionic carboxylate head provides electrostatic repulsion that enhances dispersion and colloidal stability.
Additionally, sodium linoleate’s polyunsaturated hydrocarbon chain provides a biodegradable character in environmental contexts compared with many synthetic surfactants, although its oxidation susceptibility should be considered in storage and use.
FUNCTIONS (INCI) of SODIUM LINOLEATE:
*Cleansing :
Sodium Linoleate helps to keep a clean surface
*Emulsifying :
Sodium Linoleate promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
*Surfactant :
Sodium Linoleate reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used
*Viscosity controlling :
Sodium Linoleate increases or decreases the viscosity of cosmetics
SODIUM LINOLEATE IS PRESENT IN:
Sodium Linoleate is present in 0.05% of cosmetics.
*Solid soap (2.46%)
FUNCTION(S) OF THIS INGREDIENT IN COSMETIC PRODUCTS
*CLEANSING
Sodium Linoleate cleans skin, hair or teeth
*SURFACTANT - CLEANSING
Surface-active agent to clean skin, hair and / or teeth
*SURFACTANT - EMULSIFYING
Sodium Linoleate allows the formation of finely dispersed mixtures of oil and water (emulsions)
*VISCOSITY CONTROLLING
Sodium Linoleate increases or decreases the viscosity of cosmetic products
BIOLOGICAL ACTIVITY of SODIUM LINOLEATE:
Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin.
The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants.
It is used in cosmetic and personal care products.
Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.
CHEMICAL FAMILY of SODIUM LINOLEATE:
Sodium linoleate belongs to the fatty acid sodium salt family, specifically the salts of long-chain polyunsaturated fatty acids.
Sodium Linoleate is classified as an anionic surfactant because the carboxylate head group (COO⁻) carries a negative charge paired with sodium (Na⁺).
Sodium Linoleate's structure features a long aliphatic hydrocarbon chain with two cis double bonds, characteristic of omega-6 fatty acid derivatives.
PHYSICAL AND CHEMICAL PROPERTIES of SODIUM LINOLEATE:
Sodium linoleate typically appears as a white to orange or greenish crystalline powder or solid.
Commercial grades often show some color due to impurities or partial oxidation but remain predominantly solid.
Sodium Linoleate has a melting point around ~192 °C and is described as light-, air-, heat- and hygroscopic-sensitive, meaning storage in cool, dry conditions under inert gas is recommended for stability.
Sodium Linoleate is soluble in polar organic solvents such as ethanol and can dissolve or disperse in water, exhibiting surfactant behavior.
Sodium linoleate is derived from linoleic acid — a naturally occurring fatty acid found in many plant oils — and retains functional carboxylate groups that confer its ionic nature and surfactant capability.
CHEMICAL IDENTITY of SODIUM LINOLEATE:
Sodium linoleate is the sodium salt of linoleic acid, a polyunsaturated omega-6 fatty acid.
Sodium Linoleate is an anionic surfactant and emulsifying agent that appears as a solid powder and is widely used in personal care, industrial and research applications.
Sodium Linoleate's CAS number is 822-17-3 and its EC (EINECS) number is 212-491-0.
The molecular formula of Sodium Linoleate is C₁₈H₃₁NaO₂, and the molecular weight is 302.43 g/mol.
Sodium linoleate is structurally represented as the sodium salt of (9Z,12Z)-octadeca-9,12-dienoic acid.
PHYSICAL and CHEMICAL PROPERTIES of SODIUM LINOLEATE:
Molecular Weight:302.4 g/mol
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:14
Exact Mass:302.22217451 Da
Monoisotopic Mass:302.22217451 Da
Topological Polar Surface Area:40.1 Ų
Heavy Atom Count:21
Formal Charge:0
Complexity:272
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:2
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Molecular Formula / Molecular Weight:C18H31NaO2 = 302.43
Physical State (20 deg.C):Solid
Storage Temperature:Refrigerated (0-10°C)
Store Under Inert Gas:Store under inert gas
Condition to Avoid:Light Sensitive,Air Sensitive,Hygroscopic,Heat Sensitive
CAS RN:822-17-3
Reaxys Registry Number:4048752
PubChem Substance ID:87572023
MDL Number:MFCD00063202
ECHA EINECS - REACH Pre-Reg:212-491-0
FDA UNII:872C9A1W9I
Nikkaji Web:J195.072J
MDL:MFCD00063202
Molecular Weight:302.43323928
Formula:C18 H31 Na O2
Assay:95.00 to 100.00
Food Chemicals Codex Listed:No
Flash Point:32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:water, 8.169 mg/L @ 25 °C (est)
CAS:822-17-3
Color:White-Yellow
MDL Number:MFCD00063202
Synonym:Linoleic Acid Sodium Salt
SMILES:CCCCCC=CCC=CCCCCCCCC(=O)[O-].[Na+]
Molecular Weight (g/mol):302.434
Formula Weight:302.43
Physical Form:Crystalline Powder
Melting Point:192°C
Molecular Formula:C18H31NaO2
InChI Key:WYPBVHPKMJYUEO-UHFFFAOYSA-M
IUPAC Name:sodium;octadeca-9,12-dienoate
PubChem CID:44134802
Percent Purity:≥95.0% (T)
Chemical Name or Material:Sodium Linoleate
Synonyms:9,12-Octadecadienoic acid (9Z,12Z)-, sodium salt (1:1)
IUPAC Name:Sodium;(9Z,12Z)-octadeca-9,12-dienoate
Canonical SMILES:CCCCC/C=CC/C=CCCCCCCCC(=O)[O-].[Na+]
InChI:WYPBVHPKMJYUEO-NBTZWHCOSA-M
InChI Key:InChI=1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-
Boiling Point:360.6ºC at 760mmHg
Melting Point:192 °C
Flash Point:273ºC
Appearance:Solid
Active Content:95%
CNo Chain:C18:2
EC Number:212-491-0
Exact Mass:302.22200
Hazard Statements:Xi
H-Bond Acceptor:2
H-Bond Donor:0
Physical State:Solid
Safety Description:36
Sodium Derivative Of:Linoleate
Molecular formula:C18H31NaO2
Molecular formula furigana:C18-H31-NA-O2
Molecular weight:302.434
InChI:InChI=1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChI key:WYPBVHPKMJYUEO-NBTZWHCOSA-M
SMILES:CCCCC/C=CC/C=CCCCCCCCC(=O)O[Na]
Physical state:solid
Color:No data available
Odor:No data available
Melting point/freezing point:Melting point/ range: 230 °C
Initial boiling point and boiling range:No data available
Flammability (solid, gas):No data available
Upper/lower flammability or explosive limits:No data available
Flash point:No data available
Autoignition temperature:No data available
Decomposition temperature:No data available
pH:No data available
Viscosity:Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility:No data available
Partition coefficient:n-octanol/water:No data available
Vapor pressure:No data available
Density:No data available
Relative density:No data available
Relative vapour density:No data available
Particle characteristics:No data available
Explosive properties:No data available
Oxidizing properties:No data available
Other safety information:No data available
Product Name: Sodium linoleate
CAS No.: 822-17-3
Molecular Formula: C18H32O2.Na
InChIKeys: InChIKey=XDGBPYHYBRCREM-NBTZWHCOSA-N
Molecular Weight: 302.43
Exact Mass: 302.22200
EC Number: 212-491-0
UNII: 872C9A1W9I
DSSTox ID: DTXSID5041562
Categories: Organometallic Compounds
SA: 40.13000
XLogP3: 4.54980
Melting Point: 192 °C
Boiling Point: 360.6ºC at 760mmHg
Flash Point: 273ºC
Storage Conditions: −20°C
CBNumber:CB5450334
Molecular Formula:C18H33NaO2
Molecular Weight:304.45
MDL Number:MFCD00063202
MOL File:822-17-3.mol
Melting point:192 °C
storage temp.:-20°C
solubility:soluble in Ethanol
form:powder to crystal
color:White to Orange to Green
biological source:plant oil (safflower)
Major Application:general analytical
life science and biopharma
Cosmetics Ingredients Functions:VISCOSITY CONTROLLING
SURFACTANT - CLEANSING
SURFACTANT - EMULSIFYING
CLEANSING
InChI:1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChIKey:WYPBVHPKMJYUEO-NBTZWHCOSA-M
SMILES:[Na+].CCCCCC=C/CC=C/CCCCCCCC([O-])=O
EWG's Food Scores:1
FDA UNII:872C9A1W9I
EPA Substance Registry System:9,12-Octadecadienoic acid (9Z,12Z)-, sodium salt (822-17-3)
UNSPSC Code:12352211
NACRES:NA.25
FIRST AID MEASURES of SODIUM LINOLEATE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of SODIUM LINOLEATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of SODIUM LINOLEATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM LINOLEATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of SODIUM LINOLEATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of SODIUM LINOLEATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
