SODIUM METHYL P-HYDROXYBENZOATE

Sodium Methyl p-Hydroxybenzoate is the sodium salt form associated with methyl p-hydroxybenzoate preservation chemistry, and Sodium Methyl p-Hydroxybenzoate is used as an antimicrobial preservative in compatible aqueous formulations where improved solubility is desired.
Sodium Methyl p-Hydroxybenzoate is related to methylparaben chemistry, and Sodium Methyl p-Hydroxybenzoate is valued for antifungal preservation and easier incorporation into water-based systems compared with the non-salt ester form.
Sodium Methyl p-Hydroxybenzoate must be used according to local regulations because allowed preservatives and concentration limits vary by region and product category, and Sodium Methyl p-Hydroxybenzoate performance depends on pH, ionic strength, and preservative system design.

CAS Number: 5026-62-0 (commonly associated; grade dependent)
EC Number: 225-713-6 (commonly associated; grade dependent)
Molecular Formula: C8H7NaO3
Molecular Weight: 174.13 g/mol

Synonyms: Sodium Methyl p-Hydroxybenzoate, Sodium Methylparaben, Methylparaben Sodium Salt, Sodium 4-Hydroxybenzoate Methyl Ester (salt form), Sodium Methyl p-Hydroxybenzoate Preservative, Sodium Methyl p-Hydroxybenzoate Cosmetic Preservative, Sodium Methyl Parahydroxybenzoate, Sodium Methyl Hydroxybenzoate, Sodium Methylparaben Preservative, Methylparaben Sodium, Sodium Methyl 4-Hydroxybenzoate, Sodium Methyl Paraben, Sodium Methyl p-Hydroxybenzoate, Sodium Methyl p-Hydroxybenzoate, Sodium Methyl para-Hydroxybenzoate, Sodium Methyl para-Hydroxy Benzoate, Sodium Methyl 4-Hydroxybenzoate, Sodium 4-Hydroxybenzoic Acid Methyl Ester, Sodium Methylparaben, Sodium Methyl Paraben, Methylparaben Sodium, Methyl Paraben Sodium, Sodium p-Hydroxybenzoic Acid Methyl Ester, Sodium para-Hydroxybenzoic Acid Methyl Ester, Sodium 4-Hydroxybenzoic Acid Methyl Ester Salt, Sodium Salt of Methyl p-Hydroxybenzoate, Sodium Salt of Methylparaben, Sodium Salt of Methyl Paraben, Sodium p-Hydroxybenzoate Methyl Ester, Sodium para-Hydroxybenzoate Methyl Ester, p-Hydroxybenzoic Acid Methyl Ester Sodium Salt, para-Hydroxybenzoic Acid Methyl Ester Sodium Salt, 4-Hydroxybenzoic Acid Methyl Ester Sodium Salt, Sodium 4-(Methoxycarbonyl)phenolate, Sodium p-Carbomethoxyphenolate, Sodium para-Carbomethoxyphenolate, Sodium Methyl 4-Hydroxy Benzoate, Sodium Methyl 4-Hydroxybenzoate Preservative Grade, Sodium Methyl p-Hydroxybenzoate Preservative Grade, Sodium Methylparaben Preservative, Sodium Methyl Paraben Preservative, Sodium Methylparaben Food Grade, Sodium Methyl Paraben Food Grade, Sodium Methylparaben Pharmaceutical Grade, Sodium Methyl Paraben Pharmaceutical Grade, Sodium Methylparaben Cosmetic Grade, Sodium Methyl Paraben Cosmetic Grade, Sodium Methylparaben Technical Grade, Sodium Methyl Paraben Technical Grade, Sodium Methylparaben USP, Sodium Methyl Paraben USP, Sodium Methylparaben BP, Sodium Methyl Paraben BP, Sodium Methylparaben EP, Sodium Methyl Paraben EP, Sodium Methylparaben NF, Sodium Methyl Paraben NF, Sodium Methylparaben FCC, Sodium Methyl Paraben FCC

APPLICATIONS

Sodium Methyl p-Hydroxybenzoate is used in water-based cosmetics and personal care products to inhibit yeast and mold growth and to support overall preservation.
Sodium Methyl p-Hydroxybenzoate is incorporated into lotions and creams where improved aqueous handling supports easier manufacturing.
Sodium Methyl p-Hydroxybenzoate is used in facial products where preservative robustness is required and regulations allow.

Sodium Methyl p-Hydroxybenzoate is used in shampoos and conditioners as part of preservative systems to prevent microbial contamination in aqueous surfactant products.
Sodium Methyl p-Hydroxybenzoate is incorporated into rinse-off products where pH and ionic strength are managed for effective preservation.
Sodium Methyl p-Hydroxybenzoate is used in liquid soaps and shower gels to support fungal control in compatible formulations.

Sodium Methyl p-Hydroxybenzoate is used in personal care wipes to inhibit microbial growth in wet wipe liquids and to protect products during storage.
Sodium Methyl p-Hydroxybenzoate is incorporated into cleansing wipes where preservative efficacy must be validated with challenge testing.
Sodium Methyl p-Hydroxybenzoate is used in rinse-free products where microbial control is critical due to repeated consumer exposure.

Sodium Methyl p-Hydroxybenzoate is used in pharmaceutical syrups and oral liquids in some contexts as a preservative where allowed and where pH supports activity.
Sodium Methyl p-Hydroxybenzoate is incorporated into topical solutions and gels where antimicrobial preservation is required.
Sodium Methyl p-Hydroxybenzoate is used in creams and ointments to protect against contamination during storage and use.

Sodium Methyl p-Hydroxybenzoate is used in compounded formulations where preservative selection depends on solubility, compatibility, and regulatory constraints.
Sodium Methyl p-Hydroxybenzoate is incorporated into medical wash products to maintain microbiological quality in water-based systems.
Sodium Methyl p-Hydroxybenzoate is used in specialty topical formulations where preservative performance must be confirmed by testing.

Sodium Methyl p-Hydroxybenzoate is used in industrial water-based products such as polishes and specialty formulations to prevent microbial spoilage.
Sodium Methyl p-Hydroxybenzoate is incorporated into waterborne products where long shelf life and repeated exposure require robust preservation.
Sodium Methyl p-Hydroxybenzoate is used in laboratory reagents and buffers in niche cases where preservative function is desired and compatibility is confirmed.

Sodium Methyl p-Hydroxybenzoate is used in preservative blends with other parabens or alternative preservatives to broaden spectrum and improve challenge test results.
Sodium Methyl p-Hydroxybenzoate is incorporated into multi-preservative systems where solubility and pH are optimized for stable efficacy.
Sodium Methyl p-Hydroxybenzoate is valued because Sodium Methyl p-Hydroxybenzoate provides paraben-type antifungal preservation with improved aqueous handling when regulatory requirements and formulation conditions are satisfied.

DESCRIPTION

Sodium Methyl p-Hydroxybenzoate is the sodium salt form related to methylparaben chemistry, and Sodium Methyl p-Hydroxybenzoate is typically supplied as a white crystalline powder.
Sodium Methyl p-Hydroxybenzoate offers higher water solubility than methylparaben, but Sodium Methyl p-Hydroxybenzoate solubility and stability still depend on pH and ionic strength.
Sodium Methyl p-Hydroxybenzoate preservative efficacy depends on conversion to the active undissociated form in the formulation environment, so pH management is important for performance.

Sodium Methyl p-Hydroxybenzoate is often used with other preservatives to broaden antimicrobial spectrum and to improve robustness against bacteria.
Sodium Methyl p-Hydroxybenzoate can interact with formulation components, and high electrolyte levels can influence solubility and can impact emulsions and surfactant systems.
Sodium Methyl p-Hydroxybenzoate is regulated, and maximum allowed concentrations and permitted product categories vary by region, so compliance checks are required.

Sodium Methyl p-Hydroxybenzoate should be stored in tightly closed containers in a cool, dry place protected from moisture and contamination.
Sodium Methyl p-Hydroxybenzoate dust can irritate eyes and respiratory tract, so dust control and appropriate PPE are recommended during handling.
Sodium Methyl p-Hydroxybenzoate should be used according to supplier specifications, safety documentation, and applicable cosmetic, pharmaceutical, or food additive regulations.

PROPERTIES

Chemical Formula: C8H7NaO3
Molecular Weight: 174.13 g/mol
Common Name: Sodium Methyl p-Hydroxybenzoate
Chemical Type: Preservative salt related to paraben chemistry
Appearance: White crystalline powder
Odor: Odorless to slight characteristic odor
Solubility: Soluble in water to improved extent vs methylparaben; solubility depends on pH and ionic strength
Melting / Decomposition: Decomposes at elevated temperature (grade dependent)
pH Use Range: Most effective in mildly acidic to neutral systems (formulation dependent)
Preservative Activity: Strong antifungal; moderate antibacterial; often used in blends
Stability: Stable under recommended storage; hydrolyzes under strong alkaline conditions
Regulatory Status: Use limits and allowed categories vary by market; compliance required
Storage Temperature: 10–25°C, dry, tightly closed
Shelf Life: Typically 24–60 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during weighing and powder transfer.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses, and use dust protection as needed.
Avoid generating dust and avoid inhalation of fine powder.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use local exhaust or general ventilation where dust may be generated.
Maintain good airflow during weighing, charging, and blending operations.
Minimize airborne particulate accumulation in enclosed areas.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain free-flowing behavior.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Sweep up spilled material and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with wet wiping if needed to reduce airborne dust.

Handling Precautions:
Optimize pH and formulation design because sodium paraben salts can shift between salt and active forms, influencing efficacy and solubility.
Confirm regional regulatory limits and allowed product categories for Sodium Methyl p-Hydroxybenzoate before formulation and labeling.
Validate preservative efficacy with challenge testing because preservative performance depends strongly on formulation composition, pH, and packaging.