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CAS NUMBER: 137-16-6
EC NUMBER: 205-281-5
MOLECULAR FORMULA: CH3(CH2)10CON(CH3)CH2COONa
MOLECULAR WEIGHT: 293.38
Sodium N-Lauroylsarcosine is an anionic detergent.
Sodium N-Lauroylsarcosine has been used as one of the components of the lysing solution in the cornet assay.
Sodium N-Lauroylsarcosine has been used for lysing protoplasts in the process of chromosomal DNA isolation form.
Sodium N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency.
In addition, Sodium N-Lauroylsarcosine has been shown as a microbicide for sexually transmitted diseases.
Sodium N-Lauroylsarcosine is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sodium N-Lauroylsarcosine is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH.
Sodium N-Lauroylsarcosine has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.
PH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.
Addition of an mixture of equal parts of Sodium N-Lauroylsarcosine and the non-ionic surfactant sorbitan monolaurate (S20) to water led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone.
Such aggregates can help carry other small molecules, such as drugs, through the skin.
Sodium N-Lauroylsarcosine was sold as a special ingredient called "Gardol" in Colgate "Dental Cream", as toothpaste was then called.
Sodium N-Lauroylsarcosines current use as a preventive dentifrice is in where it is used as a surfactant.
Sodium N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoproteins; reported to inhibit hexokinase.
Sodium N-Lauroylsarcosine is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
Sodium N-Lauroylsarcosine has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
Sodium N-Lauroylsarcosine inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungistatic agent in aqueous dispersion (1%).
Sodium N-Lauroylsarcosines are reportedly are non-irritant and non-sensitizing in human skin, but they can increase the penetration of other substances through the skin and should therefore be used with caution when formulating cosmetic products that contain with other substances whose safety is based on their lack of absorption or if transdermal absorption is a concern.
Sodium N-Lauroylsarcosine is an anionic surfactant, especially suitable for the preparation of shampoo, Bath, facial cleanser, baby detergent, dishwashing detergent, etc.
Sodium N-Lauroylsarcosine is derived from sarcosine, a natural amino acid found in the human body and just about every type of biological material from animals to plants. Honest’s sarcosine is made from coconut oil.
Sodium N-Lauroylsarcosine is a cleanser and foaming agent that helps with the effectiveness and feel of our toothpaste.
Sodium N-Lauroylsarcosine is a cleansing and foaming agent, but that is where the similarities end.
Sodium N-Lauroylsarcosine is derived from sarcosine, an amino acid that occurs naturally in the body, sodium lauroyl sarcosinate is frequently heralded for being a thorough cleanser but also for being gentle.
Sodium N-Lauroylsarcosine works by attracting excess oil and dirt, then carefully removing the grime from the hair by emulsifying it so it rinses easily away with water.
In addition to cleaning the hair, regular use of a shampoo with Sodium N-Lauroylsarcosine has also been shown to improve the appearance of the hair (especially locks that are damaged) by boosting shine and body.
Sodium N-Lauroylsarcosine is a powerful anionic surfactant consisting of sarcosine and its sodium salt with functional benefits including foaming, wetting, salt tolerant, and biodegradable.
Sodium N-Lauroylsarcosine is recommended for use in shampoos, mild facial cleansers, body washes and foam baths, baby products, liquid soaps, antibacterial hand washes, shaving preparations and liquid make-up applications.
Sodium N-Lauroylsarcosine is known for its good foam-boosing abilities while improving the mildness of the formula.
Sodium N-Lauroylsarcosines performance is similar to Isethionates, another group of cleaning agents known for their gentleness.
Sodium N-Lauroylsarcosine was employed as a selective flotation collector for dolomite–apatite separation.
The influence of pH, condition time, and collector dose on the flotation performance of both apatite and dolomite minerals was investigated using single mineral and binary mixed mineral flotation experiments.
Sodium N-Lauroylsarcosine is an ionic surfactant. Sodium salt of lauroyl sarcosine is widely used in the cosmetic industry in shampoos, body washes, facial washes, foundations, bath soaps, and detergents.
Sodium N-Lauroylsarcosine is used in noncoloring shampoos, bath soaps, and detergents.
Besides Sodium N-Lauroylsarcosines use in cosmetic industry, lauroyl sarcosinate is used in adhesives and as an additive in polymers (with a maximal concentration of 0.35% according to the FDA.
Sodium N-Lauroylsarcosine is an anionic surfactant.
Sodium N-Lauroylsarcosine used for cell lysis in RNA extraction protocols as it does not produce excess foaming.
Sodium N-Lauroylsarcosine is mild and biodegradable anionic surfactants derived from fatty acids and sarcosine (amino acid).
Sodium N-Lauroylsarcosines features lather building and resistance to sebum delathering in cleaners, polymers, industrial chemicals, petroleum and lubricant products.
Sodium N-Lauroylsarcosine is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sodium N-Lauroylsarcosine has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
Sodium N-Lauroylsarcosine also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sodium N-Lauroylsarcosine is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.
Sodium N-Lauroylsarcosine can reduce the irritation caused by the residue of traditional surfactants on the skin with it's good compatibility properties.
As Sodium N-Lauroylsarcosine has good biodegrability, Sodium N-Lauroylsarcosine is in accordance with the requirement of environmental protection.
Sodium N-Lauroylsarcosine is very mild, but also very effective.
What’s more, FDA approved as an indirect food additive, and CIR approved when used in rinse-off products, or in leave-on products at concentrations of 5% or less.
Sodium N-Lauroylsarcosine has a wide range of application because of it's good foambility in comparatively wider PH value range.
Sodium N-Lauroylsarcosine has good resistance to hard water, good foam stability, and is less affected by hard water than other types of surfactants.
Because sulfate-free, Sodium N-Lauroylsarcosine is widely used in shampoos, especially in anti-dandruff shampoo.
The reason is Sodium N-Lauroylsarcosine contributes to the suspension of ZPT，also anti-dandruff agent has certain irritation to the hair.
Sodium N-Lauroylsarcosine can significantly reduce the side effects, and reduce excessive degreasing, so that the scalp is not dried after washing, reducing dandruff caused by scratching and infection.
Sodium N-Lauroylsarcosine are mild, biodegradable anionic surfactants derived from fatty acids and sarcosine.
Sodium N-Lauroylsarcosine is used as a foaming and cleansing agent for shampoo, shaving foams and foam washes.
Sodium N-Lauroylsarcosine is used as a corrosion inhibitor and in formulating textile treatment agents.
Sodium N-Lauroylsarcosine is the salt of lauryl sarcosine.
Sodium N-Lauroylsarcosine is a powder or liquid and is derived from coconut.
Sodium N-Lauroylsarcosines grow around the world in lowland tropical and subtropical areas where annual precipitation is low.
Widely cultivated, healthy Sodium N-Lauroylsarcosines produce 50 nuts per year, and the tree can be used to produce everything from food and drink to fibers, building materials, and natural ingredients.
Sodium N-Lauroylsarcosine is a surfactant that allows water and oil to mix, allowing things to become clean.
Sodium N-Lauroylsarcosine also acts as a conditioning agent.
Sodium N-Lauroylsarcosine can be found in hundreds of personal care products such as shampoo, shaving cream, facial cleanser, soap, makeup, and other products.
Sodium N-Lauroylsarcosine is made with coconut acid and sarcosine, which is a breakdown product of creatine or caffeine.
Sodium N-Lauroylsarcosine is a natural amino acid found in muscle and body tissue.
Commercially, the ingredient is made in the presence of sodium hydroxide; Sodium N-Lauroylsarcosine is then purified by recrystallizing it from alcohol or by acidifying it with mineral acid, separating the free acid, and neutralizing the free acid.
Sodium N-Lauroylsarcosine is a much milder anionic surfactant than sulfate compounds.
Sodium N-Lauroylsarcosine is derived from fatty acids and natural amines.
Sodium N-Lauroylsarcosine is used in the composition of gentle cleansing products and is also used in toothpastes.
USES:
Sodium N-Lauroylsarcosine is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-Lauroylsarcosine is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-Lauroylsarcosine is personal care products as well as in household and industrial applications.
Sodium N-Lauroylsarcosine is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
Sodium N-Lauroylsarcosine can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.
Sodium N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase.
Sodium N-Lauroylsarcosine is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
Sodium N-Lauroylsarcosine has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
Sodium N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins.
Due to Sodium N-Lauroylsarcosines microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).
Sodium N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency.
In addition, Sodium N-Lauroylsarcosine has been shown as a microbicide for sexually transmitted diseases.
APPLICATION:
Sodium N-Lauroylsarcosine is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sodium N-Lauroylsarcosine is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-Lauroylsarcosine is a high foam, eco-friendly surfactant.
Sodium N-Lauroylsarcosine has good chlorine stability with anti-corrosion properties.
Sodium N-Lauroylsarcosine has excellent ocular tolerance and gentleness.
Sodium N-Lauroylsarcosine is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sodium N-Lauroylsarcosine has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
Sodium N-Lauroylsarcosine also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sodium N-Lauroylsarcosine is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.
FUNCTION:
-Antistatic: Reduces static electricity by neutralizing the electrical charge on a surface
-Cleaning agent: Helps keep a surface clean
-Emulsifying agent: Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
-Foaming agent: Captures small bubbles of air or other gases in a small volume of liquid by changing the surface tension of the liquid
-Hair conditioner: Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
-Skin conditioning agent: Keeps the skin in good condition
-Surfactant: Reduces the surface tension of cosmetics and contributes to the even distribution of the product during use
-Viscosity control agent: Increases or decreases the viscosity of cosmetics
CLASSIFICATION:
-Antistatic
-Cleansing
-Emulsifying
-Foaming
-Hair conditioning
-Skin conditioning
-Surfactant
-Viscosity controlling
PROPERTIES:
-Quality Level: 200
-description: anionic
-assay: ≥94%
-form: powder
-mol wt: micellar avg mol wt 600, average mol wt 600
-aggregation number: 2
-technique(s): oligo synthesis: suitable
-CMC: 14.6 mM (20-25°C)
-solubility: H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
-SMILES string: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
SPECIFICATION:
-CAS Min %: 94
-CAS Max %: 100
-Appearance: Almost clear in water
-pH: 7.0 to 9.0
-Color: White
-Melting Point: 45.0°C to 47.0°C
-Loss on Drying: 7% max. ()
-Assay Percent Range: 0.95
-Infrared Spectrum: Authentic
-Linear Formula: NaCO2CH2N(CH3)CO(CH2)10CH3
-Packaging: Glass bottle
-Merck Index: 154401
PHYSICAL AND CHEMICAL PROPERTIES:
-Density: 1.14 g/cm3 (20 °C)
-Flash point: 267 °C
-Melting Point: 146 °C
-pH value: 8 (30 g/l, H₂O, 20 °C)
-Vapor pressure: 0.02 hPa (20 °C)
-Bulk density: 400 kg/m3
STORAGE:
Store below +30°C.
SYNONYM:
N-Lauroylsarcosine sodium salt
Sarkosyl NL
Sodium N-lauroylsarcosina
Sodium lauroyl sarcosinate
Sarkosyl
Gardol
Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt
Sarcosyl NL
Sarcosyl
Maprosyl 30
Compound 105
Hamposyl L-30
Medialan LL-99
Sarcosyl NL 30
Sarkosyl NL 30
Sarkosyl NL 35
Sarkosyl NL 97
Sarkosyl NL 100
Sodium lauroylsarcosine
MFCD00042728
Sodium N-lauroylsarcosine
N-Lauroylsarcosine, sodium
Lauroylsarcosine sodium salt
sodium lauroyl sarcosine
UNII-632GS99618
