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SODIUM PHOSPHATE


CAS NO:7601-54-9
EC NO:231-509-8

Sodium phosphate is a generic term for a variety of salts of sodium (Na+) and phosphate (PO43−). Phosphate also forms families or condensed anions including di-, tri-, tetra-, and polyphosphates. Most of these salts are known in both anhydrous (water-free) and hydrated forms. The hydrates are more common than the anhydrous forms.

Uses
Sodium phosphates have many applications in food and for water treatment. For example, sodium phosphates are often used as emulsifiers (as in processed cheese),thickening agents, and leavening agents for baked goods. They are also used to control pH of processed foods.They are also used in medicine for constipation and to prepare the bowel for medical procedures. Moreover, they are used in detergents for softening water, and as an efficient anti rust solution.

General description
Sodium phosphate is a colorless to white crystalline powder or granules. 
Sodium phosphate is prepared by neutralization of phosphoric acid under controlled conditions with sodium hydroxide or sodium carbonate .

Application
Sodium phosphate is used as a:
component in the preparation of solid crystals of calcium hydroxyapatite substituted by strontium
block buffer to study segmental and subcellular distribution of CFTR in the kidney

Other general uses are as pH control agent, water hardness precipitation, laboratory reagent, phosphatizing reagent.

Uses in food
Sodium phosphate can be found in fast food, deli meat, processed meat, canned tuna, baked goods, and other manufactured foods. 
Sodium phosphate serves a variety of functions:

Sodium phosphate thickens food. 
Sodium phosphate stabilizes the texture of processed foods, such as mashed potato mixes.
Sodium phosphate cures meat and meat products. 
Sodium phosphate helps to keep deli meats and bacon moist, avoiding spoilage.
Sodium phosphate’s a leavening agent. 
Sodium phosphate helps dough rise in commercially prepared cakes and breads and in cake mixes.
Sodium phosphate’s an emulsifying agent. 
Sodium phosphate acts as a stabilizer to keep oil and water mixed together in certain types of food, such as processed cheese.
Sodium phosphate balances pH levels in processed food. 
Sodium phosphate stabilizes the balance between acidity and alkalinity, extending shelf life and improving taste.

Sodium phosphate is an umbrella term that refers to multiple combinations of sodium (salt) and phosphate (an inorganic, salt-forming chemical). Food-grade sodium phosphate is recognized by the U.S. Food and Drug Administration (FDA) as safe for consumption. 
Sodium phosphate is often used as an additive in processed food manufacturing. 
Sodium phosphate’s also an ingredient in many household products and medications. For some people, sodium phosphate may be used to prepare the bowel prior to colonoscopy.

An inorganic compound used as a laxative, dietary supplement and for electrolyte-replacement purposes. Phosphate, a predominant intracellular anion, plays an important role in energy storage, osteoblastic and osteoclastic activities, regulating serum calcium concentrations, and numerous cellular phosphate-transfer reactions. 
Sodium phosphate increases fluidity of the intestinal contents by retention of water by osmotic forces, thereby indirectly inducing intestinal smooth muscle constriction. 
Sodium phosphate is also used in the renal excretion of hydrogen ions while promoting the reabsorption of sodium ions.

Sodium phosphate definition, a white, crystalline, slightly hygroscopic, water-soluble powder, NaH2PO4, used chiefly in dyeing and in electroplating.

Sodium phosphate is a food additive, buffering salt and acid regulator. 
Sodium phosphate is a white crystalline powder with the chemical formula Na3PO4 .
Sodium phosphate’s heavily used in bakery, meat and dairy products.

Sodium phosphate is an additive that intensifies flavors, keeps meats moist and prevents crystals from forming in canned tuna. High blood phosphate levels might cause adverse effects, especially in people with chronic kidney disease. 

Definition and Usage Areas:

The chemical name for Sodium phosphate is phosphate in sodium. consists of two things. 
Sodium phosphate does not contain water in its anhydrous form.

Sodium phosphate is one they and one chelator. 
Sodium phosphate is synthesized from the salt of phosphoric acid (from phosphates fermented in the USA). 
Sodium phosphate acts as an emulsifier for most freezes and systemics.

Usage areas

In Sodium Wheat, products in the product package can be purchased, such as discounts at meal times.
Sodium phosphate is used together with tri sodium phosphate in multi-boiler application. 
Sodium phosphate is a free phosphate casting that delays the formation of calcium.
Sodium phosphate is used as a saline laxative for single-purpose and dibasic sodium phosphate or in preparation for a pre-colonoscopy to treat constipation.
Sodium phosphatet also acts as a thinner in industry. Tobacco is used as a humidity cabinet.
Sodium phosphate is used by default.
Sodium phosphate is used medically for washing. Simple use of doctors' research and methods. Those with observed or weakened results may have features of their scores with washing or even tens.
Sodium phosphate is found in areas of use in countries included in dairy foods. 
Sodium phosphate is an important equipment in the manufacture of pasteurized cheese and is added to milk to harden it.

Sodium phosphate is a generic term that may refer to any sodium salt of phosphoric acid. They're commonly added to food and may serve a variety of purposes. 
Sodium phosphates have been well studied and are generally considered safe when used as a food additive.

Specific Compounds
Sodium phosphate may refer to any of three specific compounds, although it most often refers to trisodium phosphate (Na3PO4) unless otherwise specified. 
Sodium dihydrogen phosphate (NaH2PO4) may also be called monosodium phosphate. Disodium hydrogen phosphate (Na2HPO4) may also be called disodium phosphate.

Sodium phosphate is an ionic compound composed of sodium cation and phosphate anion. This is a salt found both in hydrated and anhydrous salts among which anhydrous (water-free) sodium phosphate is more common in nature. 
The sodium phosphate chemical formula is Na3PO4 and it has a molecular weight of 163.94 g/mol. Besides sodium monophosphate, sodium diphosphate, triphosphate, tetraphosphate, and polyphosphates are also found in nature. As it is an ionic compound, it forms crystal structures. 
Sodium phosphate appears as white or off-white crystals, granules, or maybe in powdered form. 
Sodium phosphate has a density of 2.536 g/cc. 
Sodium phosphates boiling point is 373 k, just like water, and its melting point is 1856 

Structure of Sodium Phosphate
Sodium phosphate is an ionic compound and so exhibits an electrovalent chemical structure. The phosphate anion itself consists of a covalent structure. 
Sodium atoms have a total of 11 electrons of which one is in its outermost shell as sodium is an alkali metal. Sodium readily expels the outermost electron to produce sodium cation. Three Na+ and one PO43- get attracted to each other using the electrostatic force of attraction and a sodium phosphate molecule is generated. 

Uses of Sodium Phosphate in Industry
The most common sodium phosphate, trisodium monophosphate is mostly used as detergents, soaps, and fertilizers. 
Sodium Phosphate acts as a preservative in the processing of animals’ foods. Trisodium phosphate, along with disodium and monosodium phosphate, are used mostly as food additives. They are used as emulsifiers in processed cheese in the dairy industry. 
Sodium Phosphate is also used as a thickening agent in the bakery industry. Disodium pyrophosphate is used as a buffer. Besides, it is used in the processing of canned seafood to maintain its taste and color. 
Sodium Phosphate is also used in leather industries to get rid of stains from hides. Tetrasodium pyrophosphate is also used in the processing of canned foods as a food additive and preservative. 
Tetrasodium pyrophosphate has the unique quality of removing magnesium from the saliva so that it can reduce the accumulation of dental plaques and cavities. So this compound is uniquely used among phosphates in toothpaste. 
Sodium phosphate buffer for molecular biology, protein chemistry, and biochemical applications.

Description    
Soluble in water, and slightly soluble in alcohol.

Appearance    
White crystalline powder or granular.

Applications    
Water-processing, food additives, stain

Sodium Phosphate, especially Trisodium Phosphate (TSP) is an effective cleaning agent and is used in a variety of applications. 
Sodium Phosphate can be found as an additive in food, in household cleaners and detergents. 
Sodium Phosphate and Disodium Phosphate may be used in some laxatives, especially those used to cleanse the bowel before diagnostic procedures such as colonoscopies.

Sodium phosphate is also known as phospho soda with the formula Na3PO4 is a saline cathartic that is familiar to radiologists since it is often used as a cleansing agent prior to double contrast barium enema.

Sodium phosphate cradles are the most widely recognized, yet there is broad utilization of potassium phosphate buffer and blends of sodium and potassium. Many compounds of pharmaceutical interest are formulated in sodium phosphate buffers.

Physical Properties of Sodium Phosphate – Na3PO4
Odour:    Odourless
Appearance:    Off-white powder
Covalently-Bonded Unit:    4
Complexity:    36.8
Hydrogen Bond Acceptor:    4
Solubility:    Soluble in water

Chemical Properties of Sodium Phosphate – Na3PO4
Sodium phosphate reacts with hydrochloric acid forms phosphoric acid and sodium chloride. The chemical reaction is given below.
Na3PO4 + 3HCl → H3PO4 + 3NaCl

Sodium phosphate reacts with calcium chloride results in the formation of calcium phosphate and sodium chloride. The chemical reaction is given below.
2Na3PO4 + 3CaCl2 → 6NaCl + Ca3(PO4)2

Uses of Sodium Phosphate – Na3PO4
Short-term, local treatment of inflammation with neomycin as bacterial prophylaxis.
Sodium phosphate is used after glaucoma surgery or after cataract surgery.
Sodium phosphate is used as a mild laxative, stimulates emptying of gall-bladder.
One of the most palatable of the saline laxatives. 
Sodium phosphate is also used in the form of the oral solution (see below) as an antihypercal- cemic.
Sodium phosphate is used to control the pH of water hardness precipitation and control agent in mildly acidic solutions.

Sodium phosphate, monobasic, also known as monosodium phosphate or NAH2PO4, belongs to the class of inorganic compounds known as alkali metal phosphates. These are inorganic compounds in which the largest oxoanion is phosphate, and in which the heaviest atom not in an oxoanion is an alkali metal. Based on a literature review a significant number of articles have been published on Sodium phosphate, monobasic.

Sodium phosphate is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry. 
Sodium phosphate was applied as a fireproofing agent and for weighting silk in tanning. 
Sodium phosphate compounds, in soldering and brazing instead of borax.

Sodium phosphate (TSP) is water-soluble and widely used as a cleaning agent. 

Physical State :Solid
Solubility :Soluble in water (121 mg/ml at 20° C).
Storage :Store at room temperature
Melting Point :1583° C (lit.)
Density :1.62 g/cm3 at 20° C

Sodium phosphate, tribasic is used in soaps, detergents, photographic developers, water softeners and boiler scale removers. 
Sodium phosphate is used as a food additive, as cleaning agents, as a protein precipitant and an active ingredient in fluxes designed to deoxygenate nonferrous metals for casting. 
Sodium phosphate is used to prepare chlorinated trisodium phosphate by reacting with sodium hypochlorite and used as a disinfectant and bleach. Further, it is used in dairy substitutes and to inhibit mold. In addition, it is employed in ceramic production. 
Sodium phosphate is also used for the preservation of biologically active soil samples and fractionization of nucleotides.

About this substance
Helpful information
Sodium phosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

Sodium phosphate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses
Sodium phosphate is used in the following products: cosmetics and personal care products, fertilisers, washing & cleaning products, coating products and fillers, putties, plasters, modelling clay.
Other release to the environment of Sodium phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life
Release to the environment of Sodium phosphate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Sodium phosphate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Sodium phosphate can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Sodium phosphate can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), plastic (e.g. food packaging and storage, toys, mobile phones), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and metal (e.g. cutlery, pots, toys, jewellery).

Widespread uses by professional workers
Sodium phosphate is used in the following products: pH regulators and water treatment products, metal surface treatment products, non-metal-surface treatment products, polymers, coating products and fillers, putties, plasters, modelling clay.
Sodium phosphate is used in the following areas: agriculture, forestry and fishing.
Sodium phosphate is used for the manufacture of: metals, fabricated metal products, machinery and vehicles, pulp, paper and paper products and chemicals.
Other release to the environment of Sodium phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing
Sodium phosphate is used in the following products: pH regulators and water treatment products, fertilisers, cosmetics and personal care products and washing & cleaning products.
Release to the environment of Sodium phosphate can occur from industrial use: formulation of mixtures, formulation in materials, in processing aids at industrial sites, as processing aid, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and of substances in closed systems with minimal release.

Uses at industrial sites
Sodium phosphate is used in the following products: pH regulators and water treatment products, metal surface treatment products, non-metal-surface treatment products and fillers, putties, plasters, modelling clay.
Sodium phosphate is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Sodium phosphate is used for the manufacture of: chemicals, metals, fabricated metal products, machinery and vehicles, pulp, paper and paper products and textile, leather or fur.
Release to the environment of Sodium phosphate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

Manufacture
Release to the environment of Sodium phosphate can occur from industrial use: manufacturing of the substance, formulation of mixtures, in processing aids at industrial sites, in the production of articles, formulation in materials, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and as processing aid.


IUPAC names
Agent T148
Fosfato trisódico
Phosphoric acid, trisodium salt
risodium phosphate
Sodium orthophosphate
SODIUM PHOSPHATE
sodium phosphate
tri-sodium phosphate
Tribasic sodium orthophosphate
TRISODIUM ORTHOPHOSPHATE
Trisodium orthophosphate
trisodium orthophosphate
Trisodium orthophosphate
trisodium orthophosphate
Trisodium orthophosphate 12-hydrate
Trisodium orthophosphate dodecahydrate
trisodium orthophosphate dodecahydrate
Trisodium phosphate
trisodium phosphate
Trisodium phosphate
Trisodium phosphate dodecahydrate
Trisodium Phosphate, Tribasic Sodium Phosphate
trisodium;phosphate
trisodiumphosphate
TSP
TSP for SIEF
TSP for SIEF tri-Sodium phosphate for Quality Chemicals, S.L.


SYNONYMS:
Sodium phosphate dodecahydrate [Wiki]
Natriumphosphathydrat (3:1:12) [German] [ACD/IUPAC Name]
Phosphate de sodium, hydrate (1:3:12) [French] [ACD/IUPAC Name]
Phosphoric acid trisodium salt dodecahydrate
Phosphoric acid, trisodium salt, dodecahydrate
Sodium phosphate hydrate (3:1:12) [ACD/IUPAC Name]
Trisodium phosphate dodecahydrate
10101-89-0 [RN]
231-509-8 [EINECS]
7601-54-9 [RN]
MFCD00149198 [MDL number]
Phosphoric acid, trisodium salt, dodeahydrate
Sodium phosphate tribasic dodecahydrate
Sodium phosphate, tribasic dodecahydrate
SODIUM PHOSPHATE, TRIBASIC, DODECAHYDRATE
trisodium and phosphate and dodecahydrate
TRISODIUM ORTHOPHOSPHATE DODECAHYDRATE
TSP

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