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Sodium thioglycolate can act as a reducing agent or stabilizer in various formulations.
Sodium thioglycolate is used as an analytical reagent, but also for the preparation of chemical hot liquid
Sodium thioglycolate is widely used in hair removal (such as leather, human body), hair ironing and dyeing agent, solid and liquid media preparation.
CAS Number: 367‑51‑1
EC Number (EINECS / ELINCS): 206‑696‑4
Molecular Formula: C₂H₃NaO₂S
Molecular Weight: ~ 114.10 g/mol
SYNONYMS:
mercaptoacetic acid monosodium salt, mercaptoacetic acid sodium salt, monosodium mercaptoacetate, sodium 2-mercaptoethanoate, sodium mercaptoacetate, sodium thioglycollate, thioglycolate sodium, thioglycolic acid sodium salt, thioglycollic acid sodium salt, Sodium Thioglycolate, Sodium Mercaptoacetate, Sodium Thioglycollate, Sodium 2-Mercaptoacetate, Sodium 2-Sulfanylacetate, Thioglycolic Acid Sodium Salt, Mercaptoacetic Acid Sodium Salt, Sodium Salt of Thioglycolic Acid, Sodium Thioglycollate Solution, Sodium Mercaptoethanoate, Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt, Sodium mercaptoacetate, Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt, sodium thioglycolate, sodium mercaptoacetate, mercaptoacetic acid sodium salt, mollescal sf, sodium 2-sulfanylacetate, thioglycolate sodium, sodium thioglycollate, mercaptoacetic acid, sodium salt, erhavit d, sodium 2-mercatoethanoate, SODIUM THIOGLYCOLATE, 367-51-1, Sodium mercaptoacetate, Mercaptoacetic acid sodium salt, Thioglycolate sodium, Sodium thioglycollate, Mercaptoacetic acid, sodium salt, sodium sulfanylacetate, Sodium 2-mercatoethanoate, Thioglycollic acid, sodium salt, Acetic acid, mercapto-, monosodium salt, Thioglycolic acid, sodium salt, CCRIS 4874, USAF EK-5199, EINECS 206-696-4, EINECS 253-166-3, Thioglycolic acid sodium salt, UNII-D94M78P69V, DTXSID3026142, CHEBI:86481, SODIUM THIOGLYCOLATE [II], SODIUM THIOGLYCOLATE [MI], EC 206-696-4, 36722-22-2, SODIUM THIOGLYCOLATE (II), Sodium 2sulfanylacetate, Sodium 2mercatoethanoate, THIOGLYCOLATESODIUM, RefChem:184129, USAF EK5199, DTXCID806142, SODIUM 2-MERCAPTOETHANOATE, 2-mercaptoacetate, monosodium salt, SODIUM THIOGLYCOLATE [INCI], Acetic acid, mercapto, monosodium salt, 2Mercaptoacetic acid sodium salt (1:1), Acetic acid, 2mercapto, sodium salt (1:1), 253-166-3, sodium 2-mercaptoacetate, Sodium 2-sulfanylacetate, D94M78P69V, Mollescal SF, Acetic acid, mercapto-, sodium salt, MFCD00043386, Erhavit D, sodium,2-sulfanylacetate, Thioglycolate (sodium), Mercaptoacetic acid monosodium salt, C2H3NaO2S, SCHEMBL60834, orb1685372, sodium,2-hydroxy-2-oxoethanethiolate, AKOS015897598, CCG-214509, FM36434, HY-W115724, AS-58194, CS-0197966, M0053, NS00078303, T8530, Acetic acid, 2-mercapto-, sodium salt (1:1), E78328, F987478, Q3991662, Thioglycolic Acid Sodium Salt , Mercaptoacetic Acid Sodium Salt, thioglycolic acid sodium salt, sodium mercaptoacetate, NATG, SODIUM THIOGLYCOLATE, Sodium thioglycolate, SODIUM THIOGLYCOLLATE, SODIUM MERCAPTOACETATE, sodium sulfanylacetate, Sodium mercaptoacetate, THIOGLYCOLIC ACID SODIUM SALT, Thioglycolic acid sodium salt, Thioglycolic acid, sodium salt, Mercaptoacetic acid sodium salt, MERCAPTOACETIC ACID SODIUM SALT, Mercaptoaceticacidmonosodiumsalt, Aceticacid,mercapto-,monosodiumsalt
Sodium thioglycolate is an important flotation inhibitor.
Sodium thioglycolate is used as an inhibitor of copper minerals and pyrite in copper-molybdenum ore flotation, it has obvious inhibitory effect on copper, sulfur and other minerals, and can effectively improve the grade of molybdenum concentrate.
Sodium thioglycolate, as an effective inhibitor of a new type of sulfide ore, has been successfully used in molybdenum production for many years and has completely replaced the highly toxic inhibitor sodium cyanide.
Sodium thioglycolate (CAS 367-51-1) is a sodium salt of thioglycolic acid, appearing as a white or slightly yellowish powder, soluble in water and alcohol.
Its unique chemical structure grants Sodium thioglycolate stabilizing and reducing properties, rendering it truly valuable across many applications.
Sodium thioglycolate is the sodium salt of thioglycolic acid.
Sodium thioglycolate is a white, hygroscopic powder with a characteristic smell and is soluble in water.
Sodium thioglycolate is used mainly in cosmetic and personal care products.
Sodium thioglycolate has a special smell, and it has a slight smell when it is first made.
Sodium thioglycolate is hygroscopicity.
Exposed to the air or discolored by iron, if the color turns yellow and black, Sodium thioglycolate has deteriorated and cannot be used.
Sodium thioglycolate is soluble in water, solubility in water: 1000g/l (20°C), slightly soluble in alcohol.
Sodium thioglycolate is a sulfur-containing organic compound.
Sodium thioglycolate is a reducing agent, to break disulfide bonds in proteins.
Sodium thioglycolate is used to prevent the oxidation of growth factors and other sensitive components.
Sodium thioglycolate is utilized in the isolation of intact mitochondria from cells, as it helps to maintain the redox state of the organelles.
Sodium thioglycolate is effective in the stabilization of enzymes and other proteins, making it an important reagent in various biochemical assays.
Sodium Thioglycolate is a high-purity reducing agent for cosmetics, pharmaceuticals, textiles, photography, leather tanning, paper production, water treatment, food, and biotech applications.
Sodium thioglycolate is non-toxic, non-corrosive, and cost-effective
Sodium Thioglycolate is an organic compound and is also known as mercaptoacetic acid.
Sodium thioglycolate is colorless and contains thiol and carboxylic acid and has an unpleasant scent.
Sodium thioglycolate is a high-purity, water-soluble reducing agent widely used in various industrial applications, including cosmetics, pharmaceuticals, textiles, and oilfield operations.
Sodium thioglycolate is a sodium salt of thioglycolic acid, offering a range of benefits and advantages in different industries.
Sodium thioglycolate (C₂H₃NaO₂S) is a highly effective reducing agent widely used across science and industry.
Its unique chemical properties allow it to break the disulfide bonds in keratin, making Sodium thioglycolate a staple in cosmetic hair straighteners and depilatories, as well as an essential reagent for growing anaerobic bacteria in laboratories.
Sodium thioglycolate is a white powder with a slight odor.
Used in cold-waving of hair and as a dipilatory.
Sodium thioglycolate is an organic sodium salt having thioglycolate(1) as the counterion.
Sodium thioglycolate has a role as a reducing agent.
Sodium thioglycolate contains a thioglycolate(1-).
Based on the available data, the CIR Expert Panel concluded that ...
Sodium Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid).
Hairdressers should avoid skin contact and minimize consumer skin exposure.
Sodium Thioglycolate in depilatories is safe when formulated to be non-irritating under conditions of recommended use.
Sodium thioglycolate is the sodium salt of thioglycolic acid and is a highly water-soluble organosulfur compound widely used as a reducing agent, complexing agent, metal chelator, depilatory ingredient, cosmetic intermediate, analytical reagent, and industrial processing chemical.
Sodium thioglycolate contains both a thiol (-SH) group and a carboxylate group, giving it unique reducing and metal-binding properties.
Its strong reducing ability enables sodium thioglycolate to cleave disulfide bonds in proteins, making it an important ingredient in cosmetic depilatory formulations, permanent waving products, and specialized hair treatment systems.
In industrial chemistry, Sodium thioglycolate functions as an effective reducing agent, oxygen scavenger, metal ion complexing agent, and corrosion inhibitor.
Sodium thioglycolate is also widely employed in microbiological culture media, analytical chemistry, pharmaceutical manufacturing, mining processes, and metal surface treatment because of its ability to stabilize reduced environments and form stable complexes with numerous transition metal ions.
Its excellent water solubility, chemical versatility, and controlled reducing activity have made sodium thioglycolate valuable across numerous industrial and laboratory applications.
USES and APPLICATIONS of SODIUM THIOGLYCOLATE:
Sodium thioglycolate is used as an inhibitor for copper ore and magnesite in copper-molybdenum ore flotation.
Sodium thioglycolate is used as an analytical reagent and also used for chemical cold The preparation of hot liquid.
Sodium thioglycolate is mainly used as an inhibitor for copper-molybdenum minerals and pyrite.
Sodium thioglycolate is an effective inhibitor for the realization of cyanide-free flotation of molybdite, which can replace sodium cyanide (highly toxic) and sodium sulfide, and selectively inhibit copper and sulfur symbiotic with molybdite, especially for copper sulfide and pyrite.
Sodium thioglycolate is non-toxic and has played a positive role in the environmental protection of the production area.
Sodium thioglycolate is an environmentally friendly non-polluting mineral processing product actively recommended by the national environmental protection department.
Sodium thioglycolate's uses span personal care, cosmetics, and the pharmaceutical industry.
Sodium thioglycolate plays a pivotal role in hair care products due to its regenerative capabilities.
In the pharmaceutical industry, Sodium thioglycolate serves as a stabilizing agent in drug formulation processes and as a key component in topical products for skin conditions.
In the textile industry, Sodium thioglycolate acts as an agent aiding in the transfer of designs onto fabrics as prints, facilitating dye fixation and enhancing print quality.
Additionally, Sodium thioglycolate finds application in film development within the photography and cinematography sectors, owing to its reducing properties.
Sodium thioglycolate is widely used in pharmaceutical preparations where thioglycolate functions are required.
Sodium thioglycolate can act as a reducing agent or stabilizer in various formulations.
Sodium thioglycolate is used as an analytical reagent, but also for the preparation of chemical hot liquid
Sodium thioglycolate is widely used in hair removal (such as leather, human body), hair ironing and dyeing agent, solid and liquid media preparation.
Sodium thioglycolate is a sulfur-containing organic compound.
Sodium thioglycolate is a reducing agent, to break disulfide bonds in proteins.
Sodium thioglycolate is effective in the stabilization of enzymes and other proteins, making it an important reagent in various biochemical assays.
Sodium thioglycolate is a disulfide reducing agent.
Sodium thioglycolate is one of the salts of thioglycolic acid commonly used in consumer products to wave, straighten, or remove hair, and it may remain applied to the scalp or skin for up to 1 hour.
Sodium thioglycolate is used to prevent the oxidation of growth factors and other sensitive components.
Sodium thioglycolate is utilized in the isolation of intact mitochondria from cells, as it helps to maintain the redox state of the organelles.
Sodium thioglycolate is also commonly used as an analytical reagent in the preparation of cell culture media.
Workers may be exposed through inhalation of aerosols and dermal contact to sodium thioglycolate, especially when applying hair care products to customers.
The general population may be exposed through similar routes as workers during home application of hair care products containing sodium thioglycolate.
Sodium thioglycolate acts as a reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.
Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media.
Cosmetics and Personal Care: Sodium thioglycolate is used as a reducing agent in hair care products, such as hair dyes, perms, and relaxers, to break down keratin bonds and facilitate hair straightening or curling.
Pharmaceuticals: Sodium thioglycolate is used as an intermediate in the production of certain medications, such as antibiotics and antivirals, and as a reducing agent in the synthesis of pharmaceutical compounds.
Textiles: Sodium thioglycolate is employed as a reducing agent in the production of synthetic fibres, such as nylon and polyester, to improve their strength and durability.
Photography: Sodium thioglycolate is used as a developing agent in photographic processing to reduce silver halides and produce high-quality images.
Leather Tanning: Sodium thioglycolate is used as a reducing agent in the tanning process to improve the softness and flexibility of leather.
Pulp and Paper: Sodium thioglycolate is used as a bleaching agent to improve the brightness and strength of paper products.
Water Treatment: Sodium thioglycolate is used as a reducing agent to remove heavy metals and other impurities from wastewater and industrial process water.
Food Industry: Sodium thioglycolate is used as a reducing agent in the production of certain food products, such as bread and baked goods, to improve their texture and shelf life.
Biotechnology: Sodium thioglycolate is used as a reducing agent in biotechnological applications, such as protein purification and cell culture media.
Sodium thioglycolate is extensively used in cosmetic formulations, particularly in depilatory creams, hair-removal products, and permanent waving systems, where it selectively breaks the disulfide bonds of keratin proteins, allowing controlled modification or removal of hair while maintaining formulation stability.
Sodium thioglycolate plays an important role in microbiology as a reducing agent in thioglycolate culture media, where it lowers oxidation-reduction potential and creates an environment suitable for cultivating anaerobic and microaerophilic microorganisms.
In pharmaceutical manufacturing, sodium thioglycolate serves as a reducing agent, intermediate, stabilizer, and complexing agent during the synthesis of active pharmaceutical ingredients and specialty chemical intermediates.
Sodium thioglycolate is widely employed in analytical chemistry for metal ion analysis, spectrophotometric methods, electrochemical studies, and laboratory procedures requiring selective reduction or metal complex formation.
Sodium thioglycolate functions as an efficient oxygen scavenger in industrial process systems, helping to minimize oxidative degradation of sensitive chemicals and reducing corrosion caused by dissolved oxygen.
Sodium thioglycolate is utilized in metal finishing, electroplating, metal cleaning, and surface treatment processes where its chelating ability improves metal ion control and surface quality.
In mining and mineral processing, sodium thioglycolate is used as a selective flotation reagent and metal-complexing additive for the separation and recovery of valuable ores.
Sodium thioglycolate is incorporated into textile processing chemicals, photographic processing solutions, laboratory reagents, water treatment formulations, catalyst preparation, polymer chemistry, leather processing, and specialty industrial cleaning formulations requiring reducing or complexing functionality.
Additional applications include precious metal recovery, analytical calibration, biochemical research, corrosion inhibition, environmental laboratories, and chemical synthesis involving sulfur-containing intermediates.
-The use of Sodium Thioglycolate offers several benefits and advantages, including:
High reducing power and efficiency
Excellent solubility in water
Non-toxic and non-corrosive properties
Stability over a wide pH range
Cost-effective compared to other reducing agents
APPLICATION OF SODIUM THIOGLYCOLATE IN THE SEPARATION OF COPPER AND LEAD:
Sodium thioglycolate, as a non-toxic, small molecule inhibitor, has a good inhibition effect on chalcopyrite, and can be applied in the separation process of copper-lead mixed concentrate to achieve the separation of copper and lead.
Factors such as the dedrug effect, the type and dosage of the collector, the pulp p and H value, and the amount of sodium thioglycolate during separation have important effects on the separation effect of copper and lead, but the amount of sodium thioglycolate is the most important influencing factor.
When the amount is appropriate, the separation of copper and lead can be better achieved.
When the amount is too large, sodium thioglycolate can inhibit both of them.
Inhibition mechanism: The infrared spectral curves of sodium thioglycolate after the interaction with chalcopyrite and galena were bifurcated.
After washing, the absorption valley of these characteristic groups became weak but did not disappear completely, which proved that sodium thioglycolate coexisted with physical adsorption and chemisorption on chalcopyrite and galena surface.
Activated sphalerite with copper sulfate in high pH slurry, lime as an inhibitor of pyrrhotite and pyrite, supplemented by sodium thioglycolate, can effectively achieve zinc-sulfur separation, industrial production test obtained grade 45.10% zinc concentrate, operation recovery of 94.39%.
Sodium thioglycoacetate is a medium toxic agent, which has a good inhibition effect on pyrite and pyrrhotite, and can completely replace highly toxic cyanide to achieve cyanide-free separation process of zinc and sulfur, which not only ensures the production index of zinc concentrate grade and recovery rate, but also can meet the national environmental protection requirements.
Sodium thioglycolate has little inhibitory effect on sphalerite, and has maintained good production index since the use of sodium thioglycolate.
WHAT IS SODIUM THIOGLYCOLATE USED FOR?
Sodium thioglycolate is an important flotation inhibitor.
Sodium thioglycolate can be used as an inhibitor of copper minerals and pyrite in the flotation of copper and molybdenum ores, which has obvious inhibition effect on copper, sulfur and other minerals, and can effectively improve the grade of molybdenum concentrate.
Sodium thioglycolate, as an effective inhibitor of a new type of sulfide ore, has been successfully applied in molybdenum production for many years.
Sodium thioglycolate has the advantages of less dosage, simple and convenient usage, better cost saving and economic benefit increase.
Sodium thioglycolate not only improves the quality of the product, but also has no pollution and no toxicity, and has completely replaced the highly toxic inhibitor sodium cyanide, which has played a positive role in environmental protection of the production area.
Sodium thioglycolate can also be used as a hair removal agent.
USE & BENEFITS of SODIUM THIOGLYCOLATE:
***Antioxidant Properties:
Sodium thioglycolate functions as an antioxidant.
Our body produces free radicals due to exposure to environmental factors like radiation, pollution, and other toxic chemicals.
These free radicals break down collagen, hindering the skin repair process.
This leads to inflammation, fine lines, wrinkles, and infections like acne and dark spots.
Antioxidants scavenge these free radicals and reduce these visible signs of aging.
***Skin Enhancement:
Sodium thioglycolate brightens up the skin, stimulates collagen production, and makes the skin more healthy and youthful.
***Depilatory Function:
As a depilatory, Sodium thioglycolate helps in removing unwanted hair from the body.
***Hair Fixative:
Sodium thioglycolate also functions as a hair fixative.
Sodium thioglycolate reacts with hair fibers and helps in forming permanent waves or straightened hair.
***Application in Products:
Sodium thioglycolate is used in formulations of hair styling, bath products, and other personal care products.
CHEMICAL PROPERTIES of SODIUM THIOGLYCOLATE:
Sodium thioglycolate is the sodium salt of thioglycolic acid and readily dissociates in water to produce sodium ions and thioglycolate ions.
Sodium thioglycolate contains both a thiol (-SH) group and a carboxylate (-COO⁻) group, allowing it to function simultaneously as a reducing agent and a metal-chelating ligand.
The thiol group readily undergoes oxidation to form disulfides, providing the basis for its reducing activity in cosmetic, pharmaceutical, and industrial applications.
Sodium thioglycolate efficiently cleaves disulfide bonds present in keratin proteins, making it particularly useful in depilatory creams and permanent hair waving formulations.
Sodium thioglycolate forms stable complexes with iron, copper, mercury, silver, nickel, cobalt, and numerous other transition metal ions.
Sodium thioglycolate reacts readily with oxidizing agents, acids, and certain metal salts while remaining relatively stable under mildly alkaline storage conditions.
CHARACTERISTICS of SODIUM THIOGLYCOLATE:
Sodium thioglycolate exhibits excellent reducing capacity.
Sodium thioglycolate possesses strong metal-chelating ability.
Sodium thioglycolate demonstrates excellent water solubility.
Sodium thioglycolate efficiently cleaves disulfide bonds.
Sodium thioglycolate provides effective oxygen-scavenging performance.
Sodium thioglycolate functions as an efficient complexing agent.
Sodium thioglycolate exhibits excellent compatibility with aqueous formulations.
Sodium thioglycolate demonstrates predictable redox behavior.
Sodium thioglycolate's sulfur-containing functional group provides selective chemical reactivity.
Sodium thioglycolate is suitable for cosmetic, pharmaceutical, microbiological, and industrial applications.
Sodium thioglycolate exhibits good formulation flexibility.
Sodium thioglycolate performs efficiently over a broad concentration range.
BENEFITS of SODIUM THIOGLYCOLATE:
Sodium thioglycolate effectively reduces disulfide bonds under controlled conditions, making it valuable in cosmetic and industrial processing.
Sodium thioglycolate's excellent water solubility simplifies formulation and manufacturing.
Sodium thioglycolate provides highly efficient metal ion complexation, improving stability in numerous industrial systems.
Sodium thioglycolate's reducing properties minimize oxidation in sensitive formulations.
Sodium thioglycolate functions as an effective oxygen scavenger in specialized applications.
Sodium thioglycolate's controlled reactivity enables selective chemical transformations in laboratory and industrial synthesis.
Sodium thioglycolate improves analytical performance in metal determination procedures by stabilizing reduced metal species.
Sodium thioglycolate's compatibility with aqueous systems facilitates incorporation into numerous commercial formulations.
Sodium thioglycolate provides reproducible performance across a wide range of laboratory, cosmetic, and industrial applications.
Sodium thioglycolate's multifunctional chemical structure allows simultaneous reduction, complexation, and buffering effects in many formulations.
TECHNICAL INFORMATION of SODIUM THIOGLYCOLATE:
Sodium thioglycolate is one of the most important industrial thiol compounds due to its unique combination of reducing activity, water solubility, and metal-chelating capability.
Sodium thioglycolate's thiol functionality provides selective reduction of disulfide bonds without the aggressive behavior associated with many inorganic reducing agents.
Its excellent ability to form stable complexes with transition metals makes Sodium thioglycolate valuable in analytical chemistry, electroplating, mineral flotation, corrosion inhibition, and wastewater treatment.
In microbiology, sodium thioglycolate remains one of the most widely used reducing agents for preparing anaerobic culture media because it effectively lowers oxidation-reduction potential without significantly interfering with microbial growth.
Its combination of reducing, complexing, buffering, and oxygen-scavenging properties makes sodium thioglycolate an exceptionally versatile specialty chemical used across cosmetic, pharmaceutical, industrial, environmental, and research applications.
NATURE of SODIUM THIOGLYCOLATE:
white crystals.
Deliquescence.
Slightly special odor.
Melting point> 300 °c.
Soluble in water, slightly soluble in ethanol.
Exposure to air or in case of iron discoloration, such as color yellowing and blackening has deteriorated, can not be used.
PRODUCTION METHOD of SODIUM THIOGLYCOLATE:
cool the previously filtered thioglycolic acid to 5 ℃, slowly add sodium hydroxide solution of 40% with temperature below 5 ℃ while stirring.
when the temperature reaches 35 ℃, hydrogen sulfide gas starts to escape.
when the solution is pink and stable crystals are precipitated, stop adding sodium hydroxide: cool to room temperature, filter, the crystallization is soaked in ethanol, then washed until colorless, and dried below 80°C to obtain the finished product.
PREPARATION METHOD of SODIUM THIOGLYCOLATE:
Add a certain amount of water to a 1000mL beaker, add solid soda ash at room temperature, stir for 30 minutes to fully dissolve it, and then add chloroacetic acid for neutralization.
The neutralization reaction of chloroacetic acid is exothermic, accompanied by the release of a large amount of carbon dioxide gas, the reaction is relatively drastic, in order to control the temperature of the neutralization reaction (the temperature is too high, the temperature is too high, the temperature is too high, the temperature is too high.
Chloroacetic acid will undergo hydrolysis reaction to produce hydroxyl carboxylic acid) and prevent foam overflow during the reaction, the addition rate of chloroacetic acid is slow, and its dosage depends on the pH value of the solution;
After the solution becomes clear, pour it into a three-port flask and put it into an electric heating water bath for heating reaction.
When it reaches a certain temperature, add sodium thiosulfate crystal, stir and heat up to 85℃, and react at this temperature for 40 minutes to obtain salt.
After the temperature continues to rise to 95℃, the strong alkali thioglycolating agent solution is added, the reaction is about 40min, the heating and stirring are stopped, the natural cooling is done, and the transparent sodium thioglycolate product can be obtained after purification.
Add 185g sodium chloroacetate,29g isopropyl xanthoxanthate and appropriate amount of water into a 500ml four-mouth flask, react at 75℃ for 2h, then drop to room temperature, and slowly add 5% excess monoethylamine into the four-mouth flask with stirring.
After the addition, the temperature is raised to 70℃ and the lh is kept warm.
At this time, the reaction system changes from transparent to yellow cloudy, and finally becomes brown cloudy liquid.
Stop stirring, stand stratification, the upper layer is yellow transparent liquid, which is ethylthiamine vinegar, said the mass is 77.1g, the purity is greater than 96%, the isopropyl alcohol mass fraction is less than 3.0%;
The lower layer is dark red alkaline waste liquid, containing sodium leucyl acetate, sodium chloride, etc., which can be directly used as flotation agents.
PHYSICAL and CHEMICAL PROPERTIES of SODIUM THIOGLYCOLATE:
Appearance (of the C102L solution): Clear, nearly colorless to red-violet liquid, with a characteristic odor.
Solubility: As a salt in water, sodium thioglycolate is very soluble in water (as evidenced by its use in aqueous solutions).
Reducing Ability: Thioglycolate (–SH) groups are good reducing agents; they can reduce metal oxides and form metal-thioglycolate complexes, which is central to its cleaning action.
Stability / pH: The "C" series of Thiocare is designed to have nearly neutral pH, which minimizes corrosion to non-metal surfaces and improves safety for users.
CAS Number: 367‑51‑1 for sodium thioglycolate.
EC Number (EINECS / ELINCS): 206‑696‑4
Substance / Active: Sodium thioglycolate is the main chemical in Thiocare C102L.
Molecular Formula: C₂H₃NaO₂S (for sodium thioglycolate)
Molecular Weight: ~ 114.10 g/mol for sodium thioglycolate.
Active chemical: Sodium thioglycolate — CAS 367‑51‑1.
EC (EINECS) number: 206‑696‑4.
Product: “Thiocare® C102L 46%” is described as a ~46 % w/w Sodium thioglycolate aqueous solution (approx. 54% water).
Molecular formula: C₂H₃NaO₂S. (Often shown as C₂H₃O₂S·Na)
Molar mass: ~114.1 g mol⁻¹.
Appearance: Hygroscopic crystals/powder (for the pure salt).
Solubility: Soluble in water (e.g., ~200 mg/mL) according to Sigma‑Aldrich data.
Melting/Decomposition: For pure salt, reported melting point > 250 °C (for the “bacteriological grade” salt) or > 300 °C in NTP report.
Partition coefficient (log K_ow): –2.99 at pH 7, 22 °C (according to SDS for microbiology grade) – indicating low lipophilicity.
Density: ~1.288 g/cm³ at 20 °C (for microbiology grade)
The thioglycolate anion is a good reducing agent and forms complexes with metal ions (especially iron) via the mercapto (–SH) functionality.
Typical composition: ~46 % w/w sodium thioglycolate (= “NaTG” on spec sheet) and ~54 % water.
Typical physical form: Liquid. Appearance clear to faint violet.
pH: minimum ≈ 5.5 (as per spec sheet) for the product.
Iron (Fe) content (max) for product: ≤ 20 ppm (photometric).
Storage: In sealed original packaging rated for 6 months at room temperature (max 25 °C).
Crystallisation may occur below ~10 °C due to high salt concentration, though quality remains unaffected.
Appearance: White crystalline powder or colorless to pale yellow aqueous solution
Color: White (solid); colorless to pale yellow (solution)
Odor: Characteristic sulfur or mercaptan odor
Physical State: Solid or liquid solution
Chemical Formula: C₂H₃NaO₂S
Molecular Weight: 114.10 g/mol
Crystal Structure: Crystalline
Purity (Industrial Grade): Typically ≥98%
Density (Solid): Approximately 1.33–1.40 g/cm³
Density (Solution): Varies with concentration
Water Solubility: Completely miscible / highly soluble
Solubility in Alcohol: Slightly soluble
Solubility in Ether: Practically insoluble
pH (10% solution): Approximately 6.5–8.5
Melting Point: Decomposes upon heating (approximately 200°C)
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable
Autoignition Temperature: Not determined
Vapor Pressure: Negligible
Volatility: Low
Flammability: Not highly flammable
Oxidizing Properties: None
Reducing Properties: Strong reducing agent
Hygroscopicity: Slightly hygroscopic
Chemical Stability: Stable under recommended storage conditions
Oxidation Sensitivity: Readily oxidized by air and oxidizing agents
Light Sensitivity: Moderate
Thermal Stability: Good below decomposition temperature
Buffering Capacity: Moderate
Chelating Ability: Excellent for many transition metals
Complex Formation: Strong
Redox Activity: High
Chemical Name: Sodium Thioglycolate
IUPAC Name: Sodium 2-Sulfanylacetate
Chemical Type: Organic Sulfur Compound
Chemical Family: Thiol Carboxylate Salt
CAS No.: 367-51-1
EC No.: 206-696-4
Molecular Formula: C₂H₃NaO₂S
Molecular Weight: 114.10 g/mol
UN Number: Not generally classified as a dangerous good (classification depends on concentration and formulation)
Physical Form: White Crystalline Powder or Aqueous Solution
Chemical Classification: Thioglycolic Acid Salt / Reducing Agent
Linear Formula: HSCH2COONa
CAS Number: 367-51-1
Molecular Weight: 114.10
UNSPSC Code: 12352201
NACRES: NA.25
PubChem Substance ID: 24899901
EC Number: 206-696-4
Beilstein/REAXYS Number: 4569109
MDL Number: MFCD00043386
Physical State: solid
Color: No data available
Odor: putrid
Melting Point/Freezing Point: Melting point/ range: > 300 °C
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: No data available
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: 6,7 at 100 g/l at 20 °C
DIN 19268
Viscosity: Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water Solubility: ca.609,1 g/l at 20 °C - OECD Test Guideline 105
Partition Coefficient: n-octanol/water
log Pow: -3,78 - (Lit.), Bioaccumulation is not expected.
Vapor Pressure: < 0,1 hPa at 25 °C - (External MSDS)
Density: No data available
Relative Density: No data available
Relative Vapour Density: No data available
Particle Characteristics: No data available
Explosive Properties: Not classified as explosive.
Oxidizing Properties: none
Other Safety Information: No data available
Color: White
pH: 7.6 (5% in H2O)
Formula Weight: 114.09
Percent Purity: ≥93.0% (T)
Physical Form: Crystalline Powder
Chemical Name or Material: Sodium Thioglycolate
CAS: 367-51-1
Molecular Formula: C2H3NaO2S
Molecular Weight (g/mol): 114.094
MDL Number: MFCD00043386
InChI Key: GNBVPFITFYNRCN-UHFFFAOYSA-M
PubChem CID: 23690444
ChEBI: CHEBI:86481
IUPAC Name: sodium;2-sulfanylacetate
SMILES: C(C(=O)[O-])S.[Na+]
Molecular Weight: 114.10 g/mol
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 113.97514479 Da
Monoisotopic Mass: 113.97514479 Da
Topological Polar Surface Area: 41.1 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 46.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Canonicalized: Yes
CAS: 367-51-1
EINECS: 206-696-4
InChI: InChI=1/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
Molecular Formula: C2H5NaO2S
Molar Mass: 116.11
Melting Point: >300 °C (lit.)
Boling Point: 225.5°C at 760 mmHg
Flash Point: 99.8°C
Water Solubility: soluble
Solubility: Soluble in water, solubility in water: 1000g/l (20°C), slightly soluble in alcohol.
Vapor Presure: <0.1 hPa (25 °C)
Appearance: White to white-like powder
Color: White powder
Odor: Stench odour
Exposure Limit: ACGIH: TWA 1 ppm (Skin)
Merck: 14,8692
BRN: 4569109
pKa: 3.82[at 20 ℃]
PH: 6.7 (100g/l, H2O, 20℃)
Storage Condition: -20°C
Sensitive: Air Sensitive & Hygroscopic
MDL: MFCD00043386
FIRST AID MEASURES of SODIUM THIOGLYCOLATE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of SODIUM THIOGLYCOLATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of SODIUM THIOGLYCOLATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM THIOGLYCOLATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of SODIUM THIOGLYCOLATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of SODIUM THIOGLYCOLATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
