PRODUCTS

SODIUM THOSULFATE PENTAHYDRATE

CAS:   10102-17-7
MF:   H10Na2O8S2
MW:   248.18
EINECS:   600-156-5

Synonyms
SodiuM thiosulfate pentahydra;SodiuM Thiosulfate, 0.100 N Aqueous Solution, USP VoluMetric SolutionAPHA;Sodium thiosulfate pentahydrate 99.999% trace metals basis;Sodium thiosulfate pentahydrate ACS reagent, >=99.5%;Sodium thiosulfate pentahydrate puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%;SODIUM THIOSULFATE PENTAHYDRATE, CRYSTAL LIZED;SODIUM THIOSULF. PENTAHYDRATE FOR PHOT&;SODIUM THIOSULFATE-5-HYDRATE EXTRA PURE,

Sodium Thiosulfate Pentahydrate, with the CAS number 10102-17-7, is an inorganic compound that appears as a white crystalline solid.
Sodium Thiosulfate Pentahydrate is the pentahydrate form of sodium thiosulfate, meaning it contains five molecules of water for each molecule of sodium thiosulfate.
Sodium Thiosulfate Pentahydrate is highly soluble in water, forming a clear solution, and is known for its reducing properties.
Sodium Thiosulfate Pentahydrate is commonly used in various applications, including photography as a fixer, in water treatment processes to dechlorinate water, and in analytical chemistry as a titrant in iodometric titrations.
Sodium Thiosulfate Pentahydrate also plays a role in medicine, particularly in the treatment of cyanide poisoning.

Sodium Thiosulfate Pentahydrate is relatively stable under normal conditions but should be stored in a cool, dry place away from strong acids and oxidizing agents.
Sodium Thiosulfate Pentahydrate's safety profile indicates that it is generally considered low in toxicity, although appropriate handling and safety measures should always be observed.
Sodium Thiosulfate Pentahydrate is a chemical compound that is used in the treatment of hyperkalemia, hypoglycemia, and other metabolic disorders.
Sodium Thiosulfate Pentahydrate has been shown to have a variety of biochemical properties, including the ability to inhibit oxidation reactions by acting as an electron donor.
Sodium Thiosulfate Pentahydrate has also been shown to be effective in vitro in reducing oxidative stress-induced apoptosis and cell death.

Histological analysis of sodium thiosulfate-treated cells showed reduced DNA damage and improved cell viability.
The phase transition temperature for anhydrous sodium thiosulfate is below 0 °C.
Sodium Thiosulfate Pentahydrate reacts with potassium dichromate to produce hydrogen fluoride gas and sodium citrate.
Redox potential measurements show that Sodium Thiosulfate Pentahydrate can act as an electron acceptor when it gains electrons from hydrogen fluoride or sodium citrate, but it can also act as an electron donor when it donates electrons to hydrogen fluoride or sodium citrate.
Sodium Thiosulfate Pentahydrate has been shown to have a redox potential.
Sodium Thiosulfate Pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water.
Sodium Thiosulfate Pentahydrate has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug.
Sodium Thiosulfate Pentahydrate contains a sodium thiosulfate.

Sodium Thiosulfate Pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water.
Sodium Thiosulfate Pentahydrate has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug.
Sodium Thiosulfate Pentahydrate contains a sodium thiosulfate.
Sodium Thiosulfate Pentahydrate is a water soluble salt and reducing agent that reacts with oxidizing agents.
Although its exact mechanism of action is unknown, thiosulfate likely provides an exogenous source of sulfur, thereby hastening the detoxification of cyanide through the enzyme rhodanese (thiosulfate cyanide sulfurtransferase) which converts cyanide to the relatively nontoxic, excretable thiocyanate ion.
In addition, this agent neutralizes the reactive alkylating species of nitrogen mustard, thereby decreasing skin toxicity related to nitrogen mustard extravasation.

Sodium Thiosulfate Pentahydrate Chemical Properties
Melting point: 48.5 °C
Boiling point: 100 C
Density: 1.01 g/mL at 25 °C
Bulk density: 1000kg/m3
Refractive index: 1.489
Storage temp.: Store at +5°C to +30°C.
Solubility H2O: 1 M at 20 °C, clear, colorless
Form: Solid
Color: White tranparent
Specific Gravity: 1.729
Odor: Odorless
PH Range: 6 - 8.5
PH: 6.0-7.5 (100g/l, H2O, 20℃)
Water Solubility: 680 g/L (20 ºC)
Merck: 14,8694
Stability: Stable. Incompatible with strong acids, iodine, mercury.
InChIKey: AKHNMLFCWUSKQB-UHFFFAOYSA-L
LogP: -0.428 (est)
CAS DataBase Reference: 10102-17-7(CAS DataBase Reference)
EPA Substance Registry System: Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)

Sodium Thiosulfate Pentahydrate occurs as odorless and colorless crystals, a crystalline powder or granules.
Sodium Thiosulfate Pentahydrate is efflorescent in dry air and deliquescent in moist air.

Uses
Sodium Thiosulfate Pentahydrate is used as an analytical reagent in laboratories.
Sodium Thiosulfate Pentahydrate is used in photographic processing and in gold extraction.
Sodium Thiosulfate Pentahydrate's alkylated derivatives, S-alkylthiosulfonates, are known as Bunte salts.
Sodium Thiosulfate Pentahydrate is involved in the preparation of thioglycolic acid.
Furthermore, Sodium Thiosulfate Pentahydrate is used to dechlorinate tap water, for removing free bromine from solutions and to check the pH of bleach solutions with liquid indicators.
Other uses include tanning of leather; as an active component in hand warmers and chemical heating pads and as an anionic surfactant to aid in the dispersion of pharmaceutical preparations.

1.Used as a dechlorination agent for bleached pulp and cotton fabrics, as a chelating agent and antioxidant in the food industry, as a detergent and disinfectant in the pharmaceutical industry.
2.Sodium Thiosulfate Pentahydrate is used for dehydrochlorination of natural gas, naphtha, syngas, hydrogen and nitrogen to protect downstream catalyst from toxicity.
If there is organic chlorine in the gas, it should be converted to hydrogen chloride by cobalt-molybdenum hydrogenation catalyst, and then absorbed with dechlorinating agent.
3.Used as analytical reagent, mordant and fixative.
4.Sodium Thiosulfate Pentahydrate is suitable for removing chlorine from hydrogen, nitrogen, syngas, carbon monoxide, carbon dioxide and naphtha.
5.Photosensitive industry is used as photographic fixative.
Paper industry is used as chlorine removal agent after pulp bleaching.
The printing and dyeing industry is used as a dechlorination agent for cotton fabrics after bleaching.
Reagent for chroma analysis and volumetric analysis of analytical chemistry.
Pharmaceuticals are used as detergents and disinfectants.
The food industry is used as chelating agents, antioxidants and so on.
7.Sodium Thiosulfate Pentahydrate is used in photography, film, textile, chemical fiber, paper making, leather making and pesticide industry.
8.Used as complexing agent for silver plating of thiosulfate.
The silver plating layer has fine crystal structure and good covering ability.
The general dosage is 200~250 g/L.
Sodium Thiosulfate Pentahydrate is used as brightener in cyanide silver plating.
The dosage is 0.5 to 1.09 g/L.
Silver can be crystallized in order to obtain bright and semi bright silver plating.

Pharmaceutical Applications
Sodium Thiosulfate Pentahydrate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations).
Sodium Thiosulfate Pentahydrate has also been used for its antifungal properties and as a reagent in analytical chemistry.

Production Methods
On an industrial scale, Sodium Thiosulfate Pentahydrate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture.
Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.