SORBITAN MONOPALMITATE

SYNONYMS
Sorbitan monopalmitate; sorbitan palmitate; Span 40; Emulsifier S-40; [2-[(2R,3S,4R)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxy-ethyl] hexadecanoate 1,4-anhydro-6-O-hexadecanoyl-D-glucitol; Span 40 Spray; T/N Uniton 40S; Sorbitan Monopalmitate NF; Sorbitan Palmitate Spray; Sorbitan Hexadecanoate; SORBITAN MONOPALMITATE; Sorbitan, esters, monohexadecanoate; monohexadecanoate; 3,6-Anhydro-1-O-hexadecanoylhexitol; Sorbitan palmitate; SORBITAN MONOPALMITATE; Span 40; Glycomul P; Liposorb P; 26266-57-9; Protachem SMP; Sorbitan palmitas; 2-(3,4-dihydroxyoxolan-2-yl)-2-hydroxyethyl hexadecanoate; Arlacel 40; Crill 2; Montane 40; Nikkol SP10; Nonion PP40; Sorgen 70; Nissan nonion PP40; Rheodol SP-P 10; Sorbitan, monopalmitate; Emsorb 2510; Nissan nonion PP 40R; SORBITAN, MONOHEXADECANOATE; Sorbitan, esters, monohexadecanoate; Sorbitan monopalmitate [USAN:BAN]; Sorbester P16; 1,4-Anhydro-D-glucitol, 6-hexadecanoate; D-Glucitol, 1,4-anhydro-, 6-hexadecanoate; Sorbitan palmitate, INN; DTXSID80860361; Sorbitan monopalmitate, BAN, USAN; LMFA07011019; 3,6-Anhydro-1-O-hexadecanoylhexitol; E495; FT-0688117; NS00014101; Sorbitane Monopalmitate - Polysorbate 40 in-source fragment; (2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl hexadecanoate; D-glucitol, 1,4-anhydro-, 6-hexadecanoate; Polysorbate 40; INS No. 434; Protachem SMP; 1,4-Anhydro-D-glucitol; 1,4-Anhydro-D-sorbitol; 1,4-Sorbitan; Arlitan; Span 40; emulsifier S40; sorbitan monopalmitate; 1,4-Anhydro-6-o-palmitoyl-D-glucitol; Palmitic acid compound with (2R,3R,4S)-2-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol (1:1); almitic acid compound with (2R,3R,4S); Sorbitan,monohexadecanoate; sorgen70; Arlacel 40 Sorbitan Monopalmitate; nissannonionpp40; Span #40 (=Sorbitan monopalmitate); Sorbitan Monopalmitate (Span-40); ARLACEL 40; SORBITANMONOPALMITATE,NF; EmulsifierS40; nonionpp40; Arlacel 40 Sorbitan Monopalmitate; ARLACEL 40;SORBITAN PALMITATE;SORBITAN MONOPALMITATE;SORBITANE MONOPALMITATE;SPAN(TM) 40;SPAN NO 40;SPAN(R) 40;SPAN 40

Consists of a mixture of the partial esters of sorbitol and its mono- and dianhydrides (which have an acid value below 7.5 and a water content below 0.2%) with edible commercial palmitic acid condensed with approximately 20 moles of ethylene oxide per mole of sorbitol and its anhydrides. Around 2000, SMP was permitted by the EU in bakery products, icings, marmalades, simulations of milk and cream, beverage whiteners, liquid concentrates of fruit and herbs, sorbets, emulsified sauces, food supplements and chewing gum amongst others. SMP is a polysorbate that is derived from the mixture of partial esters of sorbitol treated with palmitic acid. SMP is a lipophilic surfactant. It may be found in combination with polysorbates. It is used to modify crystallisation of fats. It is insoluble in water. Up to 25 mg/kg bodyweight can be processed by humans. SMP is metabolized to sorbitol and palmitic acid, without any apparent side effects. The use of animal fats, like pork, in the production of SMP is possible.A mixture of the partial esters of sorbitol and its anhydrides with edible, commercial palmitic acid. Span 40 is a biodegradable surfactant based on a natural fatty acid (palmatic acid) & sugar alcohol sorbitol. This sorbitan ester is highly effective at forming oil in water emulsions, particularly when used with its polyethoxylated derivative, Tween 40.The sorbitan esters are produced by reacting the polyol, sorbitol, with a fatty acids (stearic acid, lauric acid, oleic acid, palmitic acid). Both sobitol and the fatty acids are naturally occurring and are used in cosmetic products. Sorbitan Palmitate is a surfactant and emulsifier made from palm oil and sorbitol (a natural sugar alcohol). It is biodegradable, non-toxic and a non-irritant.Sorbitan monopalmitate (Span 40) is a nonionic emulsifier, surfactant and food additive. The product of Croda Inc. Span 40 is used in skin care, hair care and decorative cosmetics. It is also used as an effector in compositions capable of facilitating penetration across a biological barrier. Inactive ingredient of some medications it improves transdermal delivery of drugs and is a potential carrier for topical drug delivery. In PLIAGLIS cream (lidocaine and tetracaine) sorbitan monopalmitate is used as an inactive ingredient. Sorbitan monopalmitate is a fatty acid sorbitan ester, yellowish brown wax, slightly soluble in isopropanol, xylene and liquid paraffin, insoluble in water, non-toxic. The main objective of the present study was to investigate the effect of polyoxyethylene sorbitan esters and sodium caseinate on physicochemical properties of palm-based functional lipid nanodispersions prepared by the emulsification-evaporation technique. The results indicated that the average droplet size increased significantly (P sodium caseinate-stabilized nanodispersions containing carotenoids had the largest average droplet size (386 nm), thus indicating a greater emulsifying role for Polysorbate 20 compared with sodium caseinate. We examined the phase behavior of various polyoxyethylene sorbitan fatty acid ester (polysorbates)/ethanol/isopropyl myristate (IPM)/150 mM NaCl solution (NaClaq) systems in order to prepare a microemulsion containing a low ratio of ethanol, which is more suitable for in vivo application. Using polyoxyethylene sorbitan trioleate (Tween 85), which has a large lipophilic moiety, as a surfactant component, single-phase domain of the phase diagram was the largest of all the polysorbates examined, and in particular a large oil-rich single-phase domain was obtained.Sorbitan monoesters of palmitic and stearic acids and triesters of stearic acid have been evaluated for acceptable daily intake by the Joint FAO/WHO Expert Committee on Food Additives in 1974 (see Annex I,Ref. 32) and a toxicological monograph was prepared (see Annex I, Ref 33). Sorbitan monoesters of oleic and lauric acids have not previously been evaluated by JECFA. The previous published monograph has been expanded to include sorbitan esters of oleic and lauric acids. products are non-ionic lipophilic surfactants, obtained by esterification of sorbitol with a fatty acid. Full range biosourced and vegetable grades are available.products are derived from monoester, sesquiester or triester of the following acids: lauric, palmitic, stearic, isostearic and oleic.emulsifiers are low coloured products, with a faint odour and low impurities content.grades have an HLB (Hydrophilic / Lipophilic Balance) range from 1.8 to 8.6.They are compatible with all surfactants and with electrolytes.They are not sensitive to pH variation. We are a client centric organization and have come up with a premium quality range of Sorbitan Monopalmitate (Span 40). This is a nonionic, lipophilic (oil loving) surfactant that is prepared using high grade ingredients and in compliance with the industry standards. It is widely used as for preparation of water in oil emulsifiers, emulsifier in leather auxiliary for some finishing formulations, opacifiers in cosmetics and also in pharmaceutical creams and lotions. We offer these Sorbitan Monopalmitate in customized specifications to meet the exact demands of clients. These are also known as Span 40. Sorbitan Stearate, Sorbitan Laurate, Sorbitan Sesquioleate, Sorbitan Oleate, Sorbitan Tristearate, Sorbitan Palmitate and Sorbitan Trioleate are white to tan-colored solids. In cosmetics and personal care products, Sorbitan Esters are used in a variety of products including skin care products, skin cleansing products, moisturizers, eye makeup and other makeup.Sorbitan Stearate, Sorbitan Laurate, Sorbitan Sesquioleate, Sorbitan Oleate, Sorbitan Tristearate, Sorbitan Palmitate and Sorbitan Trioleate function as surfactant - emulsifying agents.The sorbitan esters are produced by reacting the polyol, sorbitol, with a fatty acids (stearic acid, lauric acid, oleic acid, palmitic acid). Both sobitol and the fatty acids are naturally occurring and are used in cosmetic products. A creamy solid that helps water and oil to mix, aka emulsifier. Its solid, wax-like nature is useful for oil-based formulas where some rigidity is needed.Sorbitan" refers to the ingredient sorbitan hydride. Sorbitan consists of a mixture of several isomeric cyclic compounds, which are formed by the splitting off of a molecule of water from sorbitol. "Palmitates" means the ester palmitic acid (hexadecanoic acid).Sorbitan palmitate is used in cosmetic formulations. The sorbitan fatty acid ester acts as an emulsifier (a surface-active substance which is used as an additive in cosmetic products to combine two immiscible liquids - e.g. oil and water - to an emulsion).Sorbitan is a mixture of isomeric organic compounds that are derived from the dehydration of sorbitol and is an intermediate in the conversion of sorbitol to isosorbide. Sorbitan esters are nonionic surfactants used as emulsifying agents in the preparation of emulsions, creams, and ointments for pharmaceutical and cosmetic use. Sorbitan palmitate is a surfactant and emulsifier that is made from palm oil and sorbitol (natural sugar alcohol). It is biodegradable, non-toxic and a non-irritant.The sorbitan palmitate market has witnessed a significant growth owing to factors such as growth of chemical industry. Moreover, to provide economic factors, technology trends, and market trends that influence the global Sorbitan Palmitate market. However, less consumer knowledge related to sorbitan palmitate is projected to hamper the overall growth of the sorbitan palmitate market.cutting-edge oil-in water emulsion stabilizing agent and liquid crystal promoter lamellar liquid that actually reorganizes emulsion structure on a microscopic level, improving product performance, texture and feel. The distinct lamellar liquid crystal structure is remarkably similar to the skin’s own natural lipid structure, creating an excellent delivery system that provides superior hydrating effects due to the high water content of the liquid crystalline structure that forms when in contact with the skin. Though providing intense moisturization and skin softening abilities, it leaves a uniquely modern, light, non-greasy feel and finish that is without tackiness or whitening effect. derived from olive oil fatty acids which are naturally gentle and skin friendly, making this dynamic functional ingredient a winning choice when looking to create skin-compatible, sophisticated formulas in a wide variety of eco-friendly body and skin care products.  Simple to use, in either emulsions (at water or oil phase) or anhydrous systems, Oliwax® LC is biodegradable, ECOCERT validated and recognized by the CIR panel as safe, making it a great choice for those targeting the eco-chic, natural use and extra sensitive product categories. 

DESCRIPTION AND INGREDIENTS: Flake emulsifier and emollient. It is primarily used in o/w emulsions as an auxiliary emulsifier and stabilizer. It is a mixture of partial esters of sorbitol and anhydrides and vegetable palmitic acid. It may have free fatty acids and sorbitol, isosorbit esters.Span 40 is yellowish brown wax. It is slightly soluble in isopropanol, xylene and liquid paraffin, insoluble in water, and non-toxic. Odorless. HLB 6.7.The infrared spectrum of the sample is characteristic of a partial fatty acidester of a polyol. Sorbitan palmitate, also known as nissan nonion PP40 or arlacel 40, belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid. Sorbitan palmitate is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.Fatty acid sorbitan esters by direct reaction of sorbitol with fatty acid using a phosphorus oxyacid, including reducing phosphorus oxyacid, particularly phosphorous acid, catalyst system and an alkali or alkali earth metal base, particularly oxide, hydroxide or carbonate, in an acid:base molar ratio of 0.9:1 to 1.7:1, at a catalyst concentration of 1.5 to 30 %, particularly 3 to 12 %, by weight of sorbitol can have lower colour than products of prior commercial bulk processes even without the use of activated carbon and product bleaching typically used previously. The esters can be further reacted with alkylene oxide to make derivatives, particularly polysorbates. The esters and polyalkyleneoxy derivatives are useful surfactants in various applications. Products of low colour made without using activated carbon or bleaching are attractive for personal care applications.

APPEARANCE: Cream yellowish bead solid powders and characteristic smell. @ 25°C: White to tan bead.Odor: bland, charcacteristic. Acid value: 9.0 Maximum. Hydroxyl value: 250-300. Saponification value: 139-151. Moisture, 1.0% Maximum. Color (gardner): 5 Maximum. Assay (Fatty Acids) 63.0-71.0% Assay (Polyols; w/w) 32.0-38.0% Hydroxyl Value 275-305 Saponification Value 140-150 MAXIMUM LIMITS Acid Value 8 Water 1.5% Residue on Ignition 0.5% Heavy Metals 0.001% Residual solvents To pass test.Ivory waxy solid flakes.

SOLUBILITY: It cannot be decomposed in water.Soluble at temperatures above its melting point in ethanol, methanol, ether,ethylacetate, aniline, toluene, dioxane, petroleum ether and carbon tetrachloride; insoluble in cold water but dispersible in warm water. Soluble at temperatures above its melting point in ethanol, methanol, ether, ethyl acetate, aniline, toluene, dioxane, petroleum ether and carbon tetrachloride. Insoluble in cold water but dispersible in warm water

INTENDED USAGE: It is lipophilic surfactant substance. It is generally used as an emulsifer together with polysorbates. It is used to change crystallization of the oils.Span 40 is used as dispersant of printing inks and oils, stabilizer for emulsifying and emulsifier for oil field.A creamy solid that helps water and oil to mix, aka emulsifier. Its solid, wax-like nature is useful for oil-based formulas where some rigidity is needed.The global sorbitan palmitate market is segmented on the basis of product and application. On the basis of product, the global sorbitan palmitate market is divided into cosmetic grade and food grade. On the basis of application, the global sorbitan palmitate market is divided into cosmetic, food, and medicine.Used in skin care cosmetics. Suitable for liquid oral and topical pharmaceutical formulations.

USAGE AREA :sorbitan palmitate is an emulsifier with moisture-binding abilities. It also serves as a solubilizer of essential oils in water. It is derived from sorbitol. Sorbitan monopalmitate is a nonionic, mid-range HLB surfactant suggested for use as a w/o or an o/w emulsifier for cosmetic formulations, household products and textile chemicals. Fine bakery products, Fine bakery products, decoration and coating materials, Baker’s yeasts, Oil emulsions, Milk and cream mixtures, Gel marmelades, Tahini halva varieties, Cocoa based candies, Chocolates, Liquid mixtures of fruits and vegetables, Sweets, Sugar based candies, Food supplements. In cosmetics and personal care products, Sorbitan Esters are used in a variety of products including skin care products, skin cleansing products, moisturizers, eye makeup and other makeup.

QUANTITY OF USAGE : It is determined by the practitioner according to intended use and place of use. An oil red O fat stain is prepared by dissolving 250 mg of the dye in 100 ml of a 1% Tween 40 solution in 30% alcohol, and incubating the mixture at 60°C for 24 hr. The solution is then filtered at room temperature under vacuum through medium porosity frittedglass. Frozen sections cut from material fixed in CaCl2-CdCl2-formalin (1%:1%:10%) are placed in the stain for not less than 4 hr. After washing in the alcoholic-Tween solvent, they are mounted on glass slides from distilled water with Farrants' medium. The resulting preparations appear to be permanent, for in a 2-yr test they have remained free from stain crystalization and the fat particles are still discrete and dark red.To be stored in original packing in a shaded warehouse away from heat & direct sunlight. One year from the date of production if stored under above mentioned storage conditions in unopened packaging. 

PACKAGE FEATURES: 25 kg Kraft Bag. Pack in tightly sealed containers. Keep container tightly closed. Store in dry, cool place, and protect from moisture.