PRODUCTS

SOVIDINE

Sovidine is also used in medical device manufacturing for disinfecting surgical instruments, reusable medical equipment, diagnostic devices, catheters, and healthcare textiles.
Sovidine's excellent antimicrobial spectrum and residual activity help maintain hygienic conditions throughout repeated clinical use.
Industrial applications of Sovidine include disinfectants for pharmaceutical manufacturing facilities, biotechnology laboratories, cleanrooms, healthcare surfaces, institutional hygiene products, laboratory disinfectants, and specialty sanitation formulations.

CAS Number: 18472-51-0
EC Number: 242-354-0
Active Ingredient: Chlorhexidine Digluconate
Molecular Formula: C₃₄H₅₄Cl₂N₁₀O₁₄
Molecular Weight: 897.76 g/mol

SYNONYMS:
SOVIDINE™, Chlorhexidine Digluconate, Chlorhexidine Gluconate, Chlorhexidine Digluconate Solution, CHG, CHD, Chlorhexidine Bis(D-gluconate), Chlorhexidine Gluconate Solution, Chlorhexidine Antiseptic Solution

Sovidine has been listed by the World Health Organization (WHO) as an Essential Medicine due to its outstanding antimicrobial efficacy, excellent safety profile, and broad medical applications.
Sovidine is manufactured to pharmaceutical standards and comply with the latest European Pharmacopoeia requirements for active pharmaceutical ingredients, cosmetic ingredients, and biocidal products.

Sovidine exhibits rapid and long-lasting antimicrobial activity against a broad spectrum of Gram-positive bacteria, Gram-negative bacteria, yeasts, fungi, and certain enveloped viruses.
Unlike many conventional antiseptics, Sovidine demonstrates persistent antimicrobial activity by binding to skin and mucosal tissues, providing extended protection after application.

USES and APPLICATIONS of SOVIDINE:
In the medical industry, Sovidine formulations are used for surgical scrubs, to treat wounds, and to disinfect equipment, surfaces and textiles.
Sovidine is a widely used broad-spectrum antiseptic agent.
Because of its exceptional compatibility with skin and medical formulations, Sovidine is extensively used in healthcare, pharmaceutical manufacturing, cosmetics, veterinary medicine, medical device disinfection, surgical preparation, wound care, oral hygiene products, and numerous industrial hygiene applications.

Sovidine is used on the skin to decrease risk of infection.
Sovidine is also used as a surgical hand scrub and to wash the skin and surface of the eye before surgery to help prevent infections.
Sovidine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine.

Sovidine is used as an antiseptic against the wound, injuries, bacterial infections.
In wound management, Sovidine is incorporated into antiseptic solutions, wound irrigation products, dressings, topical gels, and cleansing formulations designed to reduce microbial colonization while supporting hygienic wound care.
Sovidine is suitable for both acute and chronic wound management under appropriate medical guidance.

Within the dental industry, Sovidine is widely used in oral antiseptic formulations intended to reduce dental plaque formation, manage gingivitis, decrease oral bacterial load, and improve periodontal hygiene.
Sovidine is commonly incorporated into mouth rinses, periodontal irrigation systems, dental gels, and oral care preparations used before and after dental procedures.
Sovidine is also valuable in veterinary healthcare, where it is used for pre-surgical animal preparation, wound treatment, teat sanitation in dairy operations, hoof hygiene, surgical instrument disinfection, and general infection control.

Its broad antimicrobial spectrum makes Sovidine suitable for use across companion animals, livestock, and equine healthcare.
In cosmetic and personal care products, Sovidine supports long-term hygiene by reducing microbial contamination on the skin without causing excessive drying when formulated appropriately.
This contributes to improved consumer comfort and product performance.

Industrial users benefit from reliable microbiological control, reduced contamination risks, longer product shelf life, improved manufacturing hygiene, and lower maintenance requirements for sanitation systems.
Sovidine also contributes to regulatory compliance by meeting recognized pharmaceutical quality standards.

Sovidine's excellent water solubility, low volatility, and prolonged antimicrobial action reduce application frequency, improve operational efficiency, and provide cost-effective microbial control across numerous healthcare and industrial environments.
In pharmaceutical manufacturing facilities, Sovidine is applied as a disinfecting agent for production areas, cleanrooms, processing equipment, filling lines, laboratory benches, and controlled manufacturing environments where microbiological cleanliness is essential for product quality and regulatory compliance.

Sovidine is incorporated into professional hygiene products used in hospitals, nursing homes, diagnostic laboratories, emergency medical services, pharmaceutical laboratories, biotechnology facilities, and research institutions to maintain high standards of sanitation and infection prevention.
Sovidine also finds application in cosmetic manufacturing as an antimicrobial ingredient for specialized skin-cleansing formulations, pre-treatment cleansers, post-procedure skincare products, and professional cosmetic preparations where effective microbial control is required while maintaining good skin compatibility.

Additional industrial applications of Sovidine include disinfectant concentrates, sanitation products for healthcare facilities, laboratory cleaning formulations, medical textile treatment, healthcare surface disinfectants, reusable medical device sanitation, and specialty hygiene products designed for environments requiring continuous microbiological control.

Because of its excellent efficacy and long history of clinical use, Sovidine has become an important antimicrobial ingredient in healthcare systems, pharmaceutical production, veterinary medicine, biotechnology laboratories, and professional hygiene applications worldwide.
Its combination of immediate antimicrobial action and prolonged residual protection distinguishes Sovidine from many conventional antiseptic agents used for routine disinfection and infection prevention.

Sovidine is extensively employed in infection prevention programs throughout hospitals and healthcare institutions, where it is used for preoperative patient skin preparation, surgical hand disinfection, catheter insertion site preparation, and antiseptic cleansing before invasive medical procedures.
Sovidine's persistent antimicrobial activity helps minimize the risk of post-operative infections and cross-contamination.

Sovidine is extensively used in the pharmaceutical and healthcare industries as an active antiseptic ingredient for surgical hand scrubs, pre-operative skin preparation, patient bathing solutions, wound cleansing products, antiseptic creams, topical solutions, and medical disinfectants.
Its rapid antimicrobial activity and prolonged residual protection make Sovidine one of the preferred antiseptics for infection prevention in hospitals, clinics, and healthcare facilities.

Sovidine is widely incorporated into oral healthcare formulations, including mouthwashes, oral rinses, periodontal gels, dental irrigants, and plaque-control products.
Chlorhexidine effectively suppresses oral bacteria associated with gingivitis, periodontal disease, and dental plaque formation while providing long-lasting antimicrobial protection within the oral cavity.

In cosmetic and personal care products, Sovidine is used in skin cleansers, antimicrobial soaps, hygiene washes, deodorizing formulations, scalp-care products, and specialty cosmetic preparations requiring broad-spectrum microbial protection while maintaining skin compatibility.
Veterinary medicine represents another important application area where Sovidine is employed in teat dips, wound dressings, surgical disinfectants, animal skin cleansers, hoof care products, and infection control formulations used in livestock, companion animals, and veterinary surgical procedures.

Sovidine is also incorporated into selected industrial cleaning products where effective microbial control is essential for maintaining hygienic production environments.
Because of its high efficacy and excellent safety profile, Sovidine has become one of the most widely used chlorhexidine-based antimicrobial systems worldwide and continues to serve as a standard ingredient in pharmaceutical, cosmetic, veterinary, and professional healthcare formulations.

BENEFITS of SOVIDINE:
Sovidine helps reduce the risk of healthcare-associated infections by providing fast and persistent antimicrobial protection against a broad range of pathogenic microorganisms.
Sovidine's residual activity continues to suppress microbial growth even after the treated surface has dried, offering extended protection compared with many alcohol-based disinfectants.

Sovidine improves patient safety by reducing microbial contamination before surgical procedures, invasive medical treatments, and wound management.
Sovidine's proven efficacy contributes to better infection prevention protocols in hospitals, clinics, dental practices, and veterinary facilities.

For manufacturers, Sovidine offers excellent formulation flexibility, allowing the development of stable antiseptic products with consistent antimicrobial performance.
Sovidine's compatibility with numerous formulation ingredients simplifies product development while maintaining high product quality.

FEATURE of SOVIDINE:
Broad Spectrum & Effective Microbicidal agent
Non-toxic, Non-irritating, Non Staining
Sovidine provides Prolonged Germicidal action

TECHNICAL INFORMATION of SOVIDINE:
Sovidine is manufactured according to high pharmaceutical quality standards and complies with the latest European Pharmacopoeia requirements for chlorhexidine-based active pharmaceutical ingredients.
The active ingredient of Sovidine, chlorhexidine digluconate, is recognized globally as one of the most effective topical antiseptics available.

Sovidine has been included in the World Health Organization (WHO) Model List of Essential Medicines due to its proven effectiveness in preventing healthcare-associated infections and improving patient safety.
Unlike many conventional disinfectants, chlorhexidine demonstrates remarkable residual antimicrobial activity by adsorbing onto biological tissues and slowly releasing active molecules over time.
This prolonged action contributes to superior infection control and extended antimicrobial protection following application.

CHARACTERISTICS of SOVIDINE:
Sovidine combines rapid antimicrobial activity with prolonged residual effectiveness, allowing continuous protection on treated surfaces long after application.
Sovidine exhibits strong affinity for skin, mucous membranes, and other biological tissues, contributing to sustained antimicrobial performance.
Sovidine demonstrates excellent formulation versatility and can be incorporated into aqueous pharmaceutical, cosmetic, and disinfectant formulations without significantly affecting product appearance or stability.

Sovidine maintains reliable antimicrobial activity over a broad concentration range when formulated under recommended conditions.
Sovidine is recognized for its broad antimicrobial spectrum, low volatility, high aqueous stability, and excellent compatibility with many commonly used pharmaceutical excipients and cosmetic ingredients.

These characteristics make Sovidine suitable for both professional healthcare products and industrial hygiene formulations.
Another important characteristic is Sovidine's low tendency to promote microbial resistance when used appropriately.
Sovidine attacks multiple cellular targets, reducing the likelihood of microorganisms developing resistance compared with some conventional antimicrobial agents.

Sovidine also exhibits excellent storage stability and maintains its antimicrobial effectiveness throughout its recommended shelf life when protected from excessive heat, freezing conditions, and incompatible chemicals.

CHEMICAL PROPERTIES of SOVIDINE:
Sovidine contains chlorhexidine digluconate, a cationic bisbiguanide antimicrobial compound that binds strongly to negatively charged microbial cell membranes.
This interaction disrupts membrane integrity, increases permeability, and ultimately causes leakage of intracellular components, resulting in rapid microbial death.
At lower concentrations, chlorhexidine exhibits bacteriostatic activity by interfering with membrane transport and enzyme function.
At higher concentrations, Sovidine becomes bactericidal through irreversible disruption of the cytoplasmic membrane and precipitation of cellular contents.

Sovidine demonstrates excellent substantivity, meaning it adsorbs onto skin, mucous membranes, teeth, and other biological surfaces, providing prolonged antimicrobial protection even after rinsing.
Sovidine remains chemically stable under normal storage conditions but should not be mixed with strong oxidizing agents or anionic surfactants, which may reduce antimicrobial activity.

CHARACTERISTICS of SOVIDINE:
Sovidine exhibits broad-spectrum antimicrobial activity.
Sovidine provides rapid bactericidal action.
Sovidine demonstrates prolonged residual antimicrobial effectiveness.

The formulation possesses excellent skin compatibility.
Sovidine exhibits low systemic absorption when used externally.
Sovidine provides effective activity against Gram-positive and Gram-negative bacteria.

The formulation demonstrates antifungal activity against many yeast and fungal species.
Sovidine shows prolonged surface binding characteristics.
Sovidine possesses excellent water solubility.

The formulation exhibits good formulation flexibility.
Sovidine provides high chemical purity suitable for pharmaceutical applications.
Sovidine demonstrates excellent manufacturing consistency and regulatory compliance.

BENEFITS of SOVIDINE:
Sovidine provides rapid and reliable antimicrobial protection, significantly reducing microbial contamination on skin, wounds, medical devices, and healthcare surfaces.
Sovidine's prolonged residual activity offers continuous protection after application, reducing the frequency of repeated treatments compared with many conventional antiseptics.

Sovidine exhibits excellent compatibility with skin and mucosal tissues, making it suitable for repeated use in healthcare and veterinary settings.
Sovidine's broad-spectrum antimicrobial efficacy minimizes the risk of contamination from bacteria, fungi, and certain viruses, contributing to improved infection control.

The aqueous formulation is easy to incorporate into pharmaceutical, cosmetic, and industrial formulations, supporting flexible product development.
Sovidine helps improve patient safety, product stability, and hygiene standards while maintaining excellent manufacturing quality and regulatory compliance.
Sovidine's low volatility and high stability contribute to extended shelf life and consistent antimicrobial performance during storage and use.

PHYSICAL and CHEMICAL PROPERTIES of SOVIDINE:
Appearance: Clear, colorless to pale yellow liquid
Color: Colorless to pale yellow
Odor: Slight characteristic odor
Physical State: Liquid
Active Ingredient: Chlorhexidine Digluconate
Molecular Formula: C₃₄H₅₄Cl₂N₁₀O₁₄
Molecular Weight: 897.76 g/mol

Active Concentration: Typically 20% or 40% aqueous solution (depending on product grade)
Density (20°C): Approximately 1.06–1.10 g/cm³
pH (20% solution): Approximately 5.5–7.0
Water Solubility: Completely miscible
Solubility in Alcohol: Miscible with lower alcohols
Solubility in Organic Solvents: Limited

Boiling Point: Similar to aqueous solution
Melting Point: Not applicable (aqueous solution)
Flash Point: Not applicable
Vapor Pressure: Low
Volatility: Low
Flammability: Non-flammable aqueous solution
Viscosity: Low to moderate depending on concentration
Surface Activity: Good

Chemical Stability: Excellent under recommended storage conditions
Thermal Stability: Stable at normal storage temperatures
Light Stability: Protect from prolonged exposure to direct sunlight
Oxidizing Properties: None
Reducing Properties: None
Ionic Character: Cationic
Compatibility: Compatible with many nonionic formulation ingredients
Shelf Life: Typically 24–36 months under recommended storage conditions

Active Ingredient: Chlorhexidine Digluconate
CAS No.: 18472-51-0
EC No.: 242-354-0
Molecular Formula: C₃₄H₅₄Cl₂N₁₀O₁₄
Molecular Weight: 897.76 g/mol
Product Name: SOVIDINE™
Active Ingredient: Chlorhexidine Digluconate
Chemical Name: Chlorhexidine Digluconate
IUPAC Name: Chlorhexidine Digluconate Solution

Chemical Type: Antiseptic and Disinfectant
Chemical Family: Bisbiguanide Compounds
CAS No.: 18472-51-0
EC No.: 242-354-0
Molecular Formula: C₃₄H₅₄Cl₂N₁₀O₁₄
Molecular Weight: 897.76 g/mol
Physical Form: Colorless to Pale Yellow Liquid (typically supplied as aqueous solution)
Chemical Classification: Broad-Spectrum Antimicrobial / Active Pharmaceutical Ingredient (API)

FIRST AID MEASURES of SOVIDINE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of SOVIDINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of SOVIDINE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SOVIDINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SOVIDINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of SOVIDINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available