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SULFAMIDIC ACID

SULFAMIDIC ACID = AMIDOSULFONIC ACID

CAS Number: 5329-14-6
EC Number: 226-218-8
MDL: MFCD00011603
Linear Formula: HSO3NH2 or H3NO3S or NH2SO3H

Sulfamidic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, sulphamic acid, is a molecular compound with the formula H3NSO3. 
This colourless, water-soluble compound finds many applications. 
Sulfamidic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.


Sulfamidic Acid (H3NSO3) may be considered an intermediate compound between sulfuric acid (H2SO4), and sulfamide (H4N2SO2), effectively replacing a hydroxyl (–OH) group with an amine (–NH2) group at each step. 
This pattern can extend no further in either direction without breaking down the sulfonyl (–SO2–) moiety. 
Sulfamates are derivatives of sulfamic acid.


Sulfamidic Acid is the simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms.
Sulfamidic Acid is an odorless, white, crystalline (sand-like) solid. 
Sulfamidic Acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.


Sulfamidic Acid is an inorganic solid acid formed by replacing the hydroxyl group of sulfuric acid with an amino group. 
Sulfamidic Acid is generally a white, odorless crystalline powder with a relative density of 2.126 and a melting point of 205°C. 
Sulfamidic Acid is easily soluble in water and liquid ammonia. 
As long as Sulfamidic Acid is kept dry and not in contact with water, solid Sulfamidic Acid does not absorb moisture and is relatively stable.


The aqueous solution of Sulfamidic Acid has the same strong acidity as hydrochloric acid and sulfuric acid, so Sulfamidic Acid is also called solid sulfuric acid. 
Sulfamidic Acid has the characteristics of non-volatile, odorless and low toxicity to human body. 
Sulfamidic Acid is also known as Sulphamic Acid, Amidosulfonic acid, Amidosulfuric acid, Minosulfonic acid.


Sulfamidic Acid is a molecular compound with the formula H3NSO3. 
Sulfamidic Acid is a dry, non-volatile, non-hygroscopic, stable solid. 
Sulfamidic Acid is soluble in water and forms a strongly acidic aqueous solution that is comparable in acidity to the common strong mineral acids, but Sulfamidic Acid can be safely handled and stored in the dry form. 


The CAS Number for Sulfamidic Acid is 5329-14-6.
Sulfamidic Acid should always be added to water, never add water to sulfamic acid.
At room temperature, diluted aqueous Sulfamidic Acid is stable for a long period of time but hydrolysis occurs at elevated temperatures.


Sulfamidic Acid is mainly a precursor to sweet-tasting compounds. 
Sulfamidic Acid is a water-soluble, moderately strong acid and an intermediate between sulfuric acid and sulfamide.
Sulfamidic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, and sulfamidic acid, is a molecular compound with the formula H3NSO3. 


This colorless, water-soluble compound finds many applications. 
Sulfamidic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.
Sulfamidic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, is a molecular compound with the formula H3NSO3.
This colourless, water-soluble compound finds many applications. 
Sulfamidic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.


Sulfamidic Acid (H3NSO3) may be considered an intermediate compound between sulfuric acid (H2SO4), and sulfamide (H4N2SO2), effectively replacing a hydroxyl (–OH) group with an amine (–NH2) group at each step.
This pattern can extend no further in either direction without breaking down the sulfonyl (–SO2–) moiety. 
Sulfamates are derivatives of sulfamic acid.
Sulfamidic Acid is mainly a precursor to sweet-tasting compounds. 


Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate. 
Sulfamidic Acid, also known as sulfamate or sulfamidic acid, belongs to the class of inorganic compounds known as other non-metal oxides. 
These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. 
Sulfamidic Acid is a bland and fatty tasting compound. 


Based on a literature review a significant number of articles have been published on Amidosulfonic acid.
Sulfamidic Acid appears as a white crystalline solid. 
Sulfamidic Acid is Density 2.1 g / cm3. 
Sulfamidic Acid is Melting point 205°C.
Sulfamidic Acid is used to make dyes and other chemicals.


Sulfamidic Acid is the simplest of the Sulfamidic Acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms.
Sulfamidic Acid Belongs to the class of inorganic compounds known as other non-metal oxides. 
These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'.


Sulfamidic Acid is White crystalline powder, odorless.  
Sulfamidic Acid is Non-volatile, non-hygroscopic.
Sulfamidic Acid is Soluble in water.  
Sulfamidic Acid is Slightly soluble in organic solvents.


Sulfamidic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, is a member of the following series of compounds: H2SO4 (sulfuric acid), H3NSO3 (sulfamic acid), H4N2SO2 (sulfamide), H5N3SO, and H6N4S.
The behavior of Sulfamidic Acid, H3NSO3, resembles that of urea, (H2N)2CO, in some ways.
Both feature amino groups linked to electron-withdrawing centers that can participate in delocalized bonding.  


Both liberate ammonia upon heating in water.
Sulfamidic Acid is a colorless, water-soluble compound.
Sulfamidic Acid is a white, crystalline solid. 
Sulfamidic Acid is soluble in water and slightly soluble in organic solvents.


Sulfamidic Acid is a unique strong inorganic acid. 
Sulfamidic Acid is white crystalline powder and easily soluble in water. 
Sulfamidic Acid's closely related to Sulphuric acid.
Sulfamidic Acid is a unique strong inorganic acid. 


Sulfamidic Acid is white crystalline powder andeasily soluble in water. 
Sulfamidic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, is a molecular compound with the formula H3NSO3. 
Sulfamidic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.
Sulfamidic Acid is also named as amidosulfuric acid, amidosulfonic acid, and aminosulfonic. 


Sulfamidic Acid is a molecular compound with chemical formula (H3NSO3). 
Sulfamidic Acid is a water-soluble, and colorless compound present in various applications. 
Sulfamidic Acid is a colourless, water-soluble compound which is widely used for various application areas. 
Also, Sulfamidic Acid (H3NSO3) is considered as an intermediate compound between sulfuric acid (H2SO4) and sulphamic (H4N2SO2).


Sulfamidic Acid or amidosulfonic acid is a colorless, water-soluble compound with the formula H3NSO3. 
Sulfamidic Acid is a molecular compound. 
This colorless, water-soluble compound has many applications. 
Sulfamidic Acid is produced industrially by treating urea with a mixture of Sulfur Trioxide and Sulphuric Acid (or oleum).


USES and APPLICATIONS of SULFAMIDIC ACID:
-Use of the substance/mixture : Laboratory chemical, Chemical intermediate
-Recommended use : Laboratory chemicals
-Sulfamidic Acid is used Adhesives , Agrichemicals , Oil Field Chemicals, Antioxidants


-Sulfamidic Acid is preferable to hydrochloric acid in household use, due to Sulfamidic Acid's intrinsic safety. 
If inadvertently mixed with hypochlorite based products such as bleach, Sulfamidic Acid does not form chlorine gas, whereas the most common acids would; the reaction (neutralisation) with ammonia, produces a salt, as depicted in the section above.


-Sulfamidic Acid also finds applications in the industrial cleaning of dairy and brewhouse equipment. 
Although Sulfamidic Acid is considered less corrosive than hydrochloric acid, corrosion inhibitors are often added to the commercial cleansers of which Sulfamidic Acid is a component. 


-Other uses:
*Catalyst for esterification process
*Dye and pigment manufacturing
*Herbicide
*Descalant for scale removal
*Coagulator for urea-formaldehyde resins
*Ingredient in fire extinguishing media. 


-Sulfamidic Acid can be used as a descalant for descaling home coffee and espresso machines and in denture cleaners.
-Sulfamidic Acid is the main raw material for ammonium sulfamate which is a widely used herbicide and fire retardant material for household products.
-Sulfamidic Acid is used Pulp and paper industry as a chloride stabilizer
-Sulfamidic Acid is used Synthesis of nitrous oxide by reaction with nitric acid


-The deprotonated form (sulfamate) is a common counterion for nickel(II) in electroplating.
-Sulfamidic Acid is used to separate nitrite ions from mixture of nitrite and nitrate ions( NO3−+ NO2−) during qualitative analysis of nitrate by Brown Ring test.
-Sulfamidic Acid is used Obtaining deep eutectic solvents with urea
-Sulfamidic Acid is used Silver polishing
-According to the label on the consumer product, the silver cleaning product TarnX contains thiourea, a detergent, and sulfamic acid.


-In which sectors is Sulfamidic Acid used: 
*Pharmaceutical industry
*Sweeteners
*Paint and pigment production
*fire prevention systems
*paper industry
*Nitrate nitrite separator in Brown ring test
*Domestic and industrial cleaner / descaler


-Sulfamidic Acid is mainly a precursor to sweet-tasting compounds. 
Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate. 
-Related compounds are also sweeteners, such as acesulfame potassium.
-SSulfamidic Acid is Used to make dyes and other chemicals.


-Sulfamates have been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), antiepileptic drugs, and weight loss drugs.


-Cleaning agent:
Sulfamidic Acid is used as an acidic cleaning agent and descaling agent sometimes pure or as a component of proprietary mixtures, typically for metals and ceramics. 
For cleaning purposes, there are different grades based on application such as GP Grade, SR Grade and TM Grade. 
Sulfamidic Acid is frequently used for removing rust and limescale, replacing the more volatile and irritating hydrochloric acid, which is cheaper. 


-When compared to most of the common strong mineral acids, Sulfamidic Acid has desirable water descaling properties, low volatility, and low toxicity. 
Sulfamidic Acid forms water-soluble salts of calcium and ferric iron.
-Sulfamidic Acid is a precursor to mainly sweet-tasting compounds. 


-Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate. 
-Related compounds are also sweeteners such as acesulfame potassium.
-Sulfamates are used in the contents of many drugs such as antibiotics, weight loss drugs, nucleoside / nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), antiepileptic drugs.


-Sulfamidic Acid is used as a catalyst for the esterification process.
-Sulfamidic Acid is used for dye and pigment production.
-Urea is used as a coagulator for formaldehyde resins.
-Sulfamidic Acid is the main raw material of ammonium sulfamate, a widely used herbicide and flame retardant material for household products.


-Sulfamidic Acid is used in the pulp and paper industry as a chloride stabilizer.
-Sulfamidic Acid is used for the synthesis of nitrous oxide by reacting with nitric acid.
-The deprotonated form (sulfamate) is a common counterion for nickel(II) in electroplating.
-Sulfamidic Acid is used to separate nitrite ions from a mixture of nitrite and nitrate ions (NO3− + NO2−) during the qualitative analysis of nitrate with the Brown Ring test.


-Sulfamidic Acid is used as an acidic cleaning agent, typically for metals and ceramics, sometimes as a component of pure or proprietary blends. 
-Sulfamidic Acid is often used to remove rust and limescale to replace the cheaper, more volatile and irritating hydrochloric acid.
-Sulfamidic Acid can be used as a descaler in domestic coffee and espresso machines and denture cleaners.
-Sulfamidic Acid can also be used for industrial cleaning of dairy and brewery equipment.


-Sulfamidic Acid is used in cleaning metal and ceramics, dye manufacturing, for stabilizing Chlorine in swimming pools, in electroplating, and as a bleaching agent. 
-Sulfamidic Acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


-Sulfamidic Acid is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), air care products, coating products, pH regulators and water treatment products, polishes and waxes and textile treatment products and dyes.
-Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
-Sulfamidic Acid is used for Electroplating.


-Sulfamidic acid is used for Cleaning oxidize surface of metal parts.
-Sulfamidic acid is used for Slightly corrosive, used as boiler scale remover or disinfectant.
-Sulfamidic acid is used for Bleacher for fibre, wood and paper.
-Sulfamidic acid is used for Remove nitrite in tobacco.


-Sulfamidic acid is used as flame retardant for cotton fibre.
-Sulfamidic acid is used as curing agent for resin.
-Sulfamidic acid is used as Intermediate of sodium cyclamate.
-Sulfamidic acid is a common chemical raw material, which can be widely used in the synthesis of herbicides, fire retardants, sweeteners, preservatives, metal cleaning agents, etc.


-Cleaning Agent: 
Sulfamidic acid as cleaning agent can be used for cleaning boilers, condensers, heat exchangers, jackets and chemical pipelines.
-Textile Industry:
Sulfamidic  acid can be used as a remover in the dye industry, a fixing agent for textile dyeing, forming a fireproof layer on textiles, and can also be used to make mesh agents and other additives in the textile industry.


-Paper Industry: 
Sulfamidic  acid can be used as a bleaching aid to reduce or eliminate the catalytic effect of heavy metal ions in the bleaching liquid, so as to ensure the quality of the bleaching liquid, and at the same time, Sulfamidic  acid can reduce the oxidative degradation of metal ions on fibers and prevent the peeling reaction of fibers, Improve the strength and whiteness of pulp.


-Oil Industry:
Sulfamidic  acid can be used to unblock the oil layer and improve the permeability of the oil layer. 
Sulfamidic  acid solution is injected into the carbonate rock oil-producing layer, because the Sulfamidic  acid is easy to react with the oil layer rock, which can avoid the deposition of salt generated by the reaction. 
Although the treatment cost is slightly higher than with hydrochloric acid, the oil production is doubled.


-Agricultural:
Sulfamidic  Acid and ammonium sulfamate were originally developed as herbicides.
-Electroplating Solution:
Sulfamidic  Acid for sale is commonly used in gilding or alloying. 
The plating solution of gilding, silver and gold-silver alloys is 60 ~ 170g sulfamic acid per liter of water.


-Sulfamidic  Acid is used for cleaning metals and ceramics; standard in alkalimetry; nitrite removal in dyeing; stabilisation of chlorine and hypochlorite for
swimming pools; sulfonating agent; organic synthesis; pH control; hard water scale removal; electroplating. 
Laboratory reagent.
-Sulfamidic  Acid can be used as a precursor to sweet-tasting compounds, a therapeutic drug component, an acidic cleaning agent, and a catalyst for esterification.


-Sulfamidic  Acid is commonly used as a precursor to sweet-tasting compounds and as an acidic cleaning agent.
-The main reason why Sulfamidic  acid is used in oil and gas drilling is to reduce the pH of used extraction fluids and compounds prior to the disposal of these fluids. 
The benefits of using Sulfamidic  acid is its ease of handling, solubility and low corrosiveness.


-Sulfamidic  Acid can also be used as an acidic cleaning agent, sometimes on Sulfamidic  Acid's own or mixed with other products, typically for metals and ceramics. 
-Sulfamidic  Acid is frequently used for removing rust and limescale.
-Sulfamidic  Acid is produced industrially by treating urea with a mixture of sulfur trioxide and sulfuric acid (or oleum). 
Sulfamic acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.


-Sulfamidic  Acid/ Sulfamic Acid  is main raw material for Sodium Cyclamate and AK (Acesulfame Potassium)
-Sulfamidic  Acid/ Sulfamic Acid is used as an herbicide, fine retardant, depurative of metal, pottery and porcelain.
-Sulfamidic  Acid/ Sulfamic Acid  is used as softener and bleacher of paper and textile.
-Sulfamidic  Acid/ Sulfamic Acid  is used as catalyst for the synthesis of urearesin.


-Sulfamidic  Acid/ Sulfamic Acid is used to remove nitrile during the production of azo dyes.
-Sulfamidic  Acid/ Sulfamic Acid  is used as stabilizing agent for chloridizing and bleaching in the swimming pool.
-Sulfamidic  Acid/ Sulfamic Acid is used as PT primary agent of acid base titration in analytical chemisty.


-Sulfamidic  Acid/ Sulfamic Acid is used as acidic cleaner,cleaning out the oil well, increasing oil production, galvanization, electrochemical polish and bitumen emulsifying and so on.
-Sulfamidic acid  has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs.


-Sulfamidic  acid is a white crystalline solid is used as an acidic cleaning agent, usually for ceramics and metals
-Related compounds are also sweeteners, such as acesulfame potassium.
-Sulfamates have been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), antiepileptic drugs, and weight loss drugs.


-Cleaning agent:
Sulfamic acid is used as an acidic cleaning agent, sometimes pure or as a component of proprietary mixtures, typically for metals and ceramics. 
Sulfamidic  Acid is frequently used for removing rust and limescale, replacing the more volatile and irritating hydrochloric acid, which is cheaper. 

When compared to most of the common strong mineral acids, sulfamic acid has desirable water descaling properties, low volatility, and low toxicity. 
Sulfamidic  Acid forms water-soluble salts of calcium and ferric iron.


-Sulfamidic  Acid is preferable to hydrochloric acid in household use, due to its intrinsic safety. 
-If erroneously mixed with hypochlorite based products such as bleach, Sulfamidic  Acid does not form chlorine gas, whereas the most common acids would; the reaction (neutralisation) with ammonia, produces a salt, as depicted in the section above.
-Sulfamidic  Acid also finds applications in the industrial cleaning of dairy and brewhouse equipment. 
Although Sulfamidic  Acid is considered less corrosive than hydrochloric acid, corrosion inhibitors are often added to the commercial cleansers of which Sulfamidic  Acid is a component. 


-Sulfamidic  Acid can be used for descaling home coffee and espresso machines and in denture cleaners.
-Uses:
*Metal Treatment
*Ceramics
*Descaling Agent
*Dye Manufacturing
*Removing Excess Grout
*Removing Light Rust
*Cleaning Heat Exchangers


-Common uses: 
Metal and ceramic cleaning. 
Stabilising agent for chlorine and hypochlorite in swimming pools, sulphonating agent, pH control, hard water scale removal and electroplating.
-Sulfamidic  Acid is used as a herbicide and chemical reagent; 


-Sulfamidic  Acid is used as a herbicide (ammonium sulfamate) and to stabilize chlorine for swimming pools, cooling towers, and paper mills; used in electroplating (metal salts) and acid cleaning; 
-Sulfamidic  Acid is used in photography
-Sulfamidic  Acid is used in metal and ceramic cleaning, organic synthesis, paper and textiles, for pH control, as a hard-water scale remover, in electroplating, pharmaceuticals, and some agricultural products.


-Sulfamidic  Acid especially used in cleaning Lime, scales & Rust from boiler parts, heat exchangers, cooling towers and cooling systems.
-Sulfamidic  Acid is a Versatile acid used for cleaning metal and ceramic parts and surfaces. 
Sulfamidic  Acid especially used in cleaning Lime, scales & Rust from boiler parts, heat exchangers, cooling towers and cooling systems.
-Sulfamidic  Acid is especially used in domestic applications as a replacement for hydrochloric acid, for cleaning toilets, descaling and removal of limescales.


-Sulfamidic  Acid is a Versatile acid used for cleaning metal and ceramic parts and surfaces. 
-Other applications of Sulfamidic  Acid are:
Herbicides, Proprietary formulations of toilet bowl cleaners,rust removers, lime and scale remover products, and Electroplating.
-Sulfamidic  Acid is used in metal and ceramic cleaning, organic synthesis, paper and textiles, for pH control, as a hard-water scale remover, in electroplating, pharmaceuticals, and some agricultural products.


-Sulfamidic  Acid is commonly used for metal and ceramic cleaning, hard-water scale removal, and as a stabilizing agent for chlorine and hypochlorites in swimming pools.
-Sulfamidic  Acid is considered a weak acid, Ka = 1.01 x 10−1.  
Because the solid is non-hygroscopic, Sulfamidic  Acid is used as a standard in acidometry (quantitative assays of acid content).
-Sulfamidic  Acid is most often used as an acidic cleaning agent, typically for metals and ceramics.  


-Sulfamidic  Acid is most often used as an acidic cleaning agent, typically for metals and ceramics.  
Sulfamidic  Acid is a replacement for hydrochloric acid for the removal of rust.  
-In households, Sulfamidic  Acid is often found as a descaling agent in detergents used for removal of limescale. 
-Sulfamates are also byproducts of sulfamic acid.
Sulfamidic  Acid is majorly a predecessor to sweet-tasting mixtures.


-Sulfamidic Acid is also used in the design of various types of therapeutic agents including HIV protease inhibitors (PIs), antibiotics, anti-cancer drugs (carbonic anhydrase and steroid sulfatase inhibitors), anti-epileptic drugs, nucleoside human immunodeficiency virus that are reverse transcriptase inhibitors, and weight loss drugs.


-Sulfamidic Acid is usually used to make dyes and other chemicals.
-Key applications: 
*Plating
*Cleaning products
*Corrosion inhibitor and anti-scaling agent
*Pulp and paper
*Bleaching agent
*Electroplating
*Industries
*Pulp & Paper
*Cleaning
*Coatings & Construction


-Sulfamidic Acid is inorganic acid which is used in various synthesis and compositions. 
Sulfamidic Acid is used as precursor in synthesis of artificial sweeteners. 
Sulfamidic Acid (amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, and sulfamidic acid) is very hydrophilic in nature and does not retain on reversed-phase columns. 

Acidic nature of this acid allows to retain this compound by mixed-mode mechanism. 
In current method Sulfamidic  Acid is retained by anion-exchange mechanism on Primesep SB mixed-mode anion-exchange column. 
Method employes acetonitrile and ammonium formate or formic acid. 

Sulfamidic Acid has no UV activity and needs to be detected by LC/MS, ELSD or Corona CAD. 
Retention time of sulfamic acid can be adjusted by the amount of buffer/acid in the mobile phase. 
This method can be used for analysis of organic and inorganic acids in different sample matrices.


-Sulfamic Acid is used in an wide arrange of different applications.
-Applications:
*Household
*Inks & Dyes
*Institutional & Industrial Chemicals
*Fertilizers
*Oil Field Services
*Pulp & Paper
*Water Treatment


KEY FEATURES AND BENEFITS :
*Plastic Industry: As a curing agent dyes & pigments
*Detergents: Used in sulphating, sulphonation & sulpha mating reaction
*Catalyst: Used as a catalyst in esterification process sweeteners
Removal of excess of nitrites in diazotization reaction (In dyestuff & pigment manufacturing


PRODUCTION of SULFAMIDIC ACID:
Sulfamidic  Acid is produced industrially by treating urea with a mixture of sulfur trioxide and sulfuric acid (or oleum). 
The conversion is conducted in two stages, the first being sulfamation:
OC(NH2)2 + SO3 → OC(NH2)(NHSO3H)
OC(NH2)(NHSO3H) + H2SO4 → CO2 + 2 H3NSO3
In this way, approximately 96,000 tonnes were produced in 1995.


STRUCTURE AND REACTIVITY of SULFAMIDIC ACID: 
Sulfamidic  Acid is well described by the formula H3NSO3, not the tautomer H2NSO2(OH). 
The relevant bond distances are 1.44 Å for the S=O and 1.77 Å for the S–N. 
The greater length of the S–N is consistent with a single bond. 
Furthermore, a neutron diffraction study located the hydrogen atoms, all three of which are 1.03 Å distant from the nitrogen. 
In the solid state, the molecule of Sulfamidic  Acid is well described by a zwitterionic form.


HYDROLYSIS of SULFAMIDIC ACID:
The crystalline solid is indefinitely stable under ordinary storage conditions, however, aqueous solutions of Sulfamidic  Acid slowly hydrolyse to ammonium bisulfate, according to the following reaction:

H3NSO3 + H2O → [NH4]+[HSO4]−
Sulfamidic  Acid's behaviour resembles that of urea, (H2N)2CO. 
Both feature amino groups linked to electron-withdrawing centres that can participate in delocalised bonding. 
Both liberate ammonia upon heating in water, with urea releasing CO2 while sulfamic acid releases sulfuric acid.


ACID-BASE REACTIONS of SULFAMIDIC ACID:
Sulfamidic  Acid is a moderately strong acid, Ka = 0.101 (pKa = 0.995). 
Because the solid is not hygroscopic, Sulfamidic  Acid is used as a standard in acidimetry (quantitative assays of acid content).
H3NSO3 + NaOH → NaH2NSO3 + H2O
Double deprotonation can be effected in ammonia solution to give the anion HNSO2−3.

H3NSO3 + 2 NH3 → HNSO2−3 + 2 NH+4
Reaction with nitric and nitrous acids
With nitrous acid, Sulfamidic  Acid reacts to give nitrogen:

HNO2 + H3NSO3 → H2SO4 + N2 + H2O
while with nitric acid, it affords nitrous oxide:

HNO3 + H3NSO3 → H2SO4 + N2O + H2O
Reaction with hypochlorite
The reaction of excess hypochlorite ions with Sulfamidic  Acid or a sulfamate salt gives rise reversibly to both N-chlorosulfamate and N,N-dichlorosulfamate ions.

HClO + H2NSO3H → ClNHSO3H + H2O
HClO + ClNHSO3H ⇌ Cl2NSO3H + H2O
Consequently, Sulfamidic  Acid is used as hypochlorite scavenger in the oxidation of aldehydes with chlorite such as the Pinnick oxidation.


REACTIONS WITH ALCOHOLS of SULFAMIDIC ACID:
Upon heating Sulfamidic  Acid will react with alcohols to form the corresponding organosulfates. 
Sulfamidic  Acid is more expensive than other reagents for doing this, such as chlorosulfonic acid or oleum, but is also significantly milder and will not sulfonate aromatic rings. 

Products are produced as their ammonium salts. 
Such reactions can be catalyzed by the presence of urea. 
Without the presence of any catalysts, Sulfamidic  Acid will not react with ethanol at temperatures below 100 °C.

ROH + H2NSO3H → ROS(O)2O− + NH+4
An example of this reaction is the production 2-ethylhexyl sulfate, a wetting agent used in the mercerisation of cotton, by combining sulfamic acid with 2-ethylhexanol.


SULFAMIDIC ACID MARKET: 
The major factors boosting the growth of the Sulfamidic  Acid market are high demand in the various industrial application and rising demand for personal care products in the market. 
The tendency to spend on cosmetics not immensely impacted by a slowdown, rather consumer choices during this period inclines to shift to minimum priced market products.

Personal care industry is a most attractive and potential market and thus it is expected to grow in the near future. 
Hence, demand for sulfamic acid is expected to grow in forecasted years. 

As a cleaning agent, Sulfamidic  Acid can be used in a wide variety of industries including which boost up Sulfamidic  Acid's demand across the globe in coming years. 
In addition, Sulfamidic  Acid other uses such as the catalyst for esterification process, herbicide, coagulator use for urea-formaldehyde resins, an ingredient in fire extinguishing media, and pigment & dye manufacturing.


ALTERNATIVE PARENTS of SULFAMIDIC ACID:    
*Sulfuric acid monoamides 
*Inorganic oxides 


SUBSTITUENTS of SULFAMIDIC ACID:
*Other non-metal oxide
*Sulfuric acid monoamide
*Inorganic oxide


PHYSICAL and CHEMICAL PROPERTIES of SULFAMIDIC ACID:
Molecular Weight: 97.09
Appearance Form: crystalline
Color: white
Odor: odorless
Odor Threshold: Not applicable
pH: 1,5 at 10 g/l at 20 °C
Melting point/freezing point:
Melting point/range: 215 - 225 °C - dec.


Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): The product is not flammable. 
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,008 hPa at 20 °C, 0,025 hPa at 100 °C


Vapor density: No data available
Relative density: No data available
Water solubility: 181,4 g/l at 20 °C
soluble 470 g/l at 80 °C
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: > 400 °C
Decomposition temperature: 209 °C -


Viscosity 
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Dissociation constant: -0,99 at 25 °C


Min. Purity Spec: 98%
Physical Form (at 20°C): Solid
Melting Point: 215-255°C
Density: 2.151
Long-Term Storage: Store long-term in a cool, dry place
Molecular Weight: 97.10    
XLogP3-AA: -1.6    


Hydrogen Bond Donor Count: 2    
Hydrogen Bond Acceptor Count: 4    
Rotatable Bond Count: 0    
Exact Mass: 96.98336413    
Monoisotopic Mass: 96.98336413    
Topological Polar Surface Area: 88.8 Ų    
Heavy Atom Count: 5    
Formal Charge: 0    


Complexity: 92.6    
Isotope Atom Count: 0    
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0    
Undefined Bond Stereocenter Count: 0    
Covalently-Bonded Unit Count: 1    
Compound Is Canonicalized: Yes


PSA: 88.77
XLogP3: 0.529
Appearance: white crystalline powder
Density: 2.15 g/cm3
Melting Point: 205 °C
Boiling Point: 247°C
Flash Point: 205°C
Refractive Index: 1.553
Water Solubility: H2O: 146.8 g/L (20 ºC)


Storage Conditions:
Store in a cool, dry place. 
Store in a tightly closed container. 
Do not store in metal containers.
Flammability characteristics: 
Flammability Limits = 9.3 vol%


PH:
1N, pH=0.41; 0.75N, 
pH=0.5; 0.5N, 
pH=0.63; 0.25N, 
pH=0.87; 0.1N, 
pH=1.18; 0.05N, 
pH=1.41; 0.01N, 
pH=2.02
Dissociation Constants:
Dissociation constant at 25 °C = 0.101


Appearance: white to pale yellow crystalline powder (est)
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.308 (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)


FIRST AID MEASURES of SULFAMIDIC ACID:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.

*If inhaled:
After inhalation: 
Fresh air.

*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower.

*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.

*If swallowed
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.

-Indication of any immediate medical attention and special treatment needed:
No data available


ACCIDENTAL RELEASE MEASURES of SULFAMIDIC ACID:
-Environmental precautions:
Do not let product enter drains.

-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Take up dry. 
Dispose of properly. 
Clean up affected area. 


FIRE FIGHTING MEASURES of SULFAMIDIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.


EXPOSURE CONTROLS/PERSONAL PROTECTION of SULFAMIDIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:

*Eye/face protection:
Use Safety glasses

*Skin protection:
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

*Body Protection:
protective clothing

-Control of environmental exposure:
Do not let product enter drains.


HANDLING and STORAGE of SULFAMIDIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.


STABILITY and REACTIVITY of SULFAMIDIC ACID:
-Reactivity
No data available

-Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .

-Conditions to avoid
no information available

SYNONYMS:
SULFAMIC ACID
Amidosulfonic acid
Aminosulfonic acid
Sulphamic acid
Amidosulfuric acid
Imidosulfonic acid
Sulfamidic acid
Sulfaminic acid
Jumbo
Sulphamidic acid
Aminosulfuric acid
Kyselina sulfaminova
Kyselina amidosulfonova
sulfuramidic acid
NSC 1871
UNII-9NFU33906Q
amidohydroxidodioxidosulfur
H2NSO3H
CHEMBL68253
CHEBI:9330
[S(NH2)O2(OH)]
9NFU33906Q
DSSTox_CID_14005
DSSTox_RID_79107
DSSTox_GSID_34005
Caswell No. 809
HSDB 795
UN2967
SULFAMIC ACID, ACS
EPA Pesticide Chemical Code 078101
SULFAMIC ACID, REAG
sulfoamine
Sulfamidsaeure
AI3-15024
Sulphamic-acid-
Amidoschwefelsaeure
amidosulphuric acid
Sulfamic acid [UN2967] 
WLN: ZSWQ
NH2SO3H
Sulfamic acid, ACS grade
NH3SO3
NCIOpen2_000675
Molybdenum, Quant Test Strips
DTXSID6034005
BDBM26994
NSC1871
Sulfamic acid, p.a., 99.5%
Sulfamic acid, analytical standard
NSC-1871
Sulfamic acid, reagent grade, 98%
Tox21_201905
Tox21_303482
8894AF
STL282725
7773-06-0 (mono-ammonium salt)
AKOS005287325
Sulfamic acid, ACS reagent, 99.3%
ZINC238809066
MCULE-8047713803
UN 2967
NCGC00090927-01
NCGC00090927-02
NCGC00257489-01
NCGC00259454-01
Sulfamic acid [UN2967] 
Sulfamic acid, ReagentPlus(R), >=99%
Sulfamic acid, >=99.5% (alkalimetric)
FT-0688102
Sulfamic acid, 99.999% trace metals basis
Sulfamic acid, SAJ first grade, >=99.0%
Sulfamic acid, JIS special grade, >=99.5%
Q412304
W-105754
Sulfamic acid, analytical standard (for acidimetry), ACS reagent
Sulfamic Acid
Alprojet W
Amidosulfuric Acid
Aminesulfonic Acid
Aminosulfonic Acid
Aminosulfuric Acid
Jumbo
NSC 1871
Scale Cleen
Steradent Active Plus
Sulfamidic Acid
Sulfaminic Acid
Sulphamic Acid
amidosulfonic acid
amidosulfuric acid
aminosulfonic acid
sulfamidic acid
SULFAMIC ACID
Sulfamidic acid,
Amidosulfonic acid
Jumbo
Sulphamic acid
Amidosulfuric acid
Aminosulfonic acid
Imidosulfonic acid
Sulfaminic acid
Aminosulfuric acid
Sulphamidic acid
Sulfamidsaeure
sulfuramidic acid,
Amidoschwefelsaeure
Kyselina sulfaminova
Amidosulfuric acid
Sulfaminic acid
Aminosulfonic acid
Aminosulfuric acid
Imidosulfonic acid
JUMBO
Kyselina amidosulfonova
Kyselina sulfaminova
Sulfamidic acid
Sulphamidic acid
Sulfamic acid
AI3-15024
CASWELL NO. 809
EPA PESTICIDE CHEMICAL CODE 078101
HSDB 795
NSC 1871
UN2967
Sulfamic acid
Amidosulfuric acid
Aminosulfonic acid
Sulfamidic acid
Sulphamic acid
Amidosulfonic acid
Aminosulfuric acid
Jumbo
Aminesulfonic acid
Sulfaminic acid
Sulfaminic acid
Sulfamic acid
nitrilosulphonic acid
Jumbo
Amidosulfonic acid
Sulfamidic acid
Amidosulfuric acid
Imidosulfonic acid
Sulphamic acid, 
Aminosulfonic acid
Amino sulfonic acid
Sulfamidic acid
Sulfamic acid,
Amidosulfonic acid,
Amidosulfuric acid,
Hydrogen amidotrioxosulfate
Aminosulfonic acid
Sulfamic acid, 
Sulfamic acid 99.5%
SULPHAMIC ACID 99.8%
SULFAMIC ACID REAGENT


 

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