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SYMPEPTIDE XLASH

SymPeptide XLash is a trademarked cosmetic ingredient developed, designed to enhance the appearance of eyelashes. 
SymPeptide XLash is often used in eyelash growth serums and mascaras. 
The primary function of SymPeptide XLash is to promote the growth of longer, fuller, and stronger lashes by stimulating keratin production in the hair follicles of the eyelashes.

CAS Number: 959610-30-1
Molecular Formula: C41H81N9O6
Molecular Weight: 796.14
EINECS Number: 200-001-8

Synonyms: Myristoyl Pentapeptide-17, 959610-30-1, N-((5S,8S,11S,14S,17S)-1,21-diamino-8-(4-aminobutyl)-5-carbamoyl-14-isobutyl-11-methyl-7,10,13,16-tetraoxo-6,9,12,15-tetraazahenicosan-17-yl)tetradecanamide, MyristoylPentapeptide-17, Myristoyl Pentapeptide-17?, NFPWMUOQSJXGGZ-ZZTWKDBPSA-N, HY-P0103, AKOS030632924, AC-31939, DA-65737, DS-19757, CS-0017932, C77314, A922282, N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]tetradecanamide

The key active ingredient in SymPeptide XLash is Myristoyl Pentapeptide-17, a synthetic peptide that plays a crucial role in encouraging eyelash growth. 
SymPeptide XLash does this by increasing the production of keratin, the protein that makes up the hair structure, thereby leading to thicker and longer lashes over time.
SymPeptide XLash is a synthetic fatty acid with a long chain of peptides. 

SymPeptide XLash is synthesized by reacting to Myristic acid and pentapeptide-17. 
SymPeptide XLash, as the name, indicates penta-five different peptides together, which are targeted towards certain healing treatments. 
They have amino acids which are building blocks of proteins. 

Amino acids and peptides may easily get incorporated into the other protein structure or skin/hair/nail and may make them appear positively different. 
SymPeptide XLash is an amber-colored clear liquid with a faint odor.
SymPeptide XLash acts as an eyelash enhancer. 

SymPeptide XLash increases the overall density of eyelashes by thickening and fortifying them.
SymPeptide XLash is synthetic, bio-available lipo-oligopeptide which efficiently improves eyelash volume.
SymPeptide XLash is a 3D enhancer for a dramatic beautiful look.

SymPeptide XLash is clinically proven to provide eyelashes that look thicker up to + 66%.
SymPeptide XLash is suitable for eyelash products.
SymPeptide XLash, hair care ingredients are never just products but the result of cross-category teamwork, benefiting from our acknowledged expertise in skin care, botanicals, functionals as well as fragrances. 

Driven by the emerging needs of contemporary consumers, thoroughly investigated and substantiated, each ingredient is designed to open new perspectives, facilitate innovation and manufacturing, and help our customers invent the products of tomorrow.
SymPeptide XLash is the product of the reaction of myristic acid and Pentapeptide-17.
SymPeptide XLash is multi- peptide, solid hair follicles, activate keratinous gene, booth eyelash growth, 7days with proven effect winkey patented productin China.

Its recommended dosage is 1~10%.
SymPeptide XLash, remove eye makeup and contact lenses, if worn. 
Apply product directly to both upper & lower lash lines and eyebrows. Let the serum absorb completely before applying makeup. For best results, use twice daily.

SymPeptide XLash increases the overall density and thickness of eyelashes by thickening and fortifying them.
SymPeptide XLash stimulates the keratin genes expression responsible for more densified eyelashes (in-vitro).
SymPeptide XLash is bioavailable lipo-oligopeptide (LOPs) that enhances appearance of the thickness of eyelashes. 

The results can be seen in 2 weeks. It improves eyelash density. 
SymPeptide XLash is water soluble, colorless to beige, odorless and does not impact formulation aesthetics. 
It complies with cosmetic regulation in the USA, Europe and Japan.

SymPeptide XLash enhances the appearance of eyelash length and thickness and improves eyelash density in as little as two weeks of daily use. 
After four weeks, the improvement in length, darkness, and volume is up to 66%. Superfruit extracts, Panthenol (Pro-Vitamin B5) and Malachite Extract help to stimulate new hair growth and protect against hair loss. 
This prostaglandin-free formula will not cause iris or eyelid darkening.

Bellahut's ready to use lash growth serum is a combination of two very effective peptides in a smooth serum gel base. 
It contains SymPeptide XLash which has been shown to increase lash volume by up to 25% in just 2 weeks of use and up to 66% in just 4 weeks. 
It also contains Procapil™ which is a growth peptide that helps to restore hair thickness, fullness and volume. 

A serum that is easy to apply and only requires a once daily application. 
The core active ingredient in SymPeptide XLash, Myristoyl Pentapeptide-17, is a synthetic peptide composed of five amino acids linked to a myristic acid chain. 
This structure enables the peptide to penetrate the skin effectively and stimulate keratin genes within the hair follicles.

Keratin Stimulation: Keratin is a fibrous protein that is a key structural component of hair, including eyelashes. 
By enhancing keratin production, SymPeptide XLash helps to fortify the lashes, making them appear thicker and more resilient.
SymPeptide XLash is commonly found in eyelash serums, where it is formulated to be applied directly to the lash line. 

With consistent use, users can expect to see visible improvements in the length, density, and overall appearance of their eyelashes.
Some mascaras include SymPeptide XLash as an active ingredient to not only enhance the immediate look of the lashes but also to support their long-term health and growth.
Benefits
Regular use of products containing SymPeptide XLash can lead to noticeably longer lashes over time, as the peptide promotes the growth phase of the hair cycle.

By stimulating keratin production, SymPeptide XLash helps in thickening the lashes, making them appear fuller and more voluminous.
Safe and Non-Irritating: Designed for use around the sensitive eye area, SymPeptide XLash is generally formulated to be non-irritating and safe for regular use.
SymPeptide XLash works by mimicking natural growth factors within the body. 

When applied to the lash line, the peptide penetrates the follicle, where it interacts with keratinocytes—the cells responsible for producing keratin. 
This interaction triggers the upregulation of keratin production, leading to stronger and longer lash fibers.
Users typically start to see visible results after a few weeks of consistent application, with the most significant improvements often noticeable after 6-8 weeks.

For sustained results, ongoing use is recommended. 
If use is discontinued, lashes may gradually return to their natural growth cycle.

Products containing SymPeptide XLash are often dermatologically tested to ensure they are safe for use around the delicate eye area.
Clinical studies conducted by Symrise and independent laboratories have demonstrated the efficacy of SymPeptide XLash in promoting eyelash growth, confirming its benefits through measurable increases in lash length and volume.

Boiling point: 1071.6±65.0 °C(Predicted)
Density: 1.062±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 13.42±0.46(Predicted)
color: white powder
Water Solubility: soluble in water
InChIKey: NFPWMUOQSJXGGZ-ZZTWKDBPSA-N
SMILES: C(N)(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCC
EWG's Food Scores: 1

SymPeptide XLash is a result of advancements in peptide technology, where specific sequences of amino acids are designed to trigger biological responses. 
SymPeptide XLash, the active component, is a pentapeptide, meaning it consists of five amino acids. 
The addition of a myristoyl group (a fatty acid) helps the peptide to penetrate the lipid-rich layers of the skin, allowing it to reach the hair follicles more effectively.

The primary mechanism involves binding to the receptors in the dermal papilla cells, which are located at the base of the hair follicle. 
This binding triggers a cascade of signals that upregulate the production of keratin, the structural protein that makes up hair. 
The peptide essentially encourages the follicles to produce thicker and longer hairs by prolonging the anagen (growth) phase of the hair cycle.

SymPeptide XLash was developed by Symrise, a global supplier of cosmetic ingredients known for innovation in the beauty and personal care sector. 
SymPeptide XLash has focused on creating scientifically-backed, effective, and safe ingredients for skin and hair care.
Developing a peptide like SymPeptide XLash involves ensuring stability and bioavailability in a cosmetic formulation. 

The peptide needs to remain stable in the SymPeptide XLash over its shelf life while maintaining its efficacy. 
This requires careful consideration of the formulation's pH, the presence of stabilizing agents, and the type of delivery system used.
Beyond eyelash serums and mascaras, SymPeptide XLash has potential applications in eyebrow growth treatments and other hair-enhancing products. 

The versatility of peptide technology allows it to be incorporated into various cosmetic formulations, from serums to creams, to enhance the appearance of hair on different parts of the body.
SymPeptide XLash is often combined with other active ingredients, such as biotin, panthenol, or hyaluronic acid, in cosmetic formulations. 
These ingredients work synergistically to provide additional benefits, such as moisturizing the lashes, strengthening the hair shaft, and supporting overall lash health.

The efficacy of SymPeptide XLash has been demonstrated in clinical studies, where subjects have reported significant improvements in lash length, thickness, and overall appearance. 
These studies typically involve a placebo-controlled setup to ensure the results are directly attributable to the peptide.
Users of SymPeptide XLash typically observe a gradual improvement in the appearance of their lashes, with full results often visible after 8 to 12 weeks of consistent use. 

The peptide’s ability to extend the anagen phase means that lashes grow longer and remain in the growth phase for a longer period before transitioning to the resting phase.
SymPeptide XLash is generally regarded as safe for use in cosmetic products. 
SymPeptide XLash has been formulated to minimize irritation and is often tested under ophthalmological control, given its application near the eyes. 

The ingredient is designed to be non-sensitizing and non-irritating, making it suitable for most skin types.
Symrise ensures that SymPeptide XLash meets all relevant regulatory requirements for cosmetic ingredients, including those set by the European Union (EU), the United States Food and Drug Administration (FDA), and other regulatory bodies. 
The ingredient is typically included in the INCI (International Nomenclature of Cosmetic Ingredients) list under its chemical name, Myristoyl Pentapeptide-17.

SymPeptide XLash has become a popular ingredient in the beauty industry due to the increasing demand for non-invasive methods to enhance natural beauty. 
With the growing trend of lash enhancements, from extensions to serums, SymPeptide XLash provides a natural, safe, and effective alternative.
Consumer feedback on products containing SymPeptide XLash is generally positive, with many users reporting noticeable improvements in their lash length and thickness. 

The ingredient’s ability to deliver visible results without the need for lash extensions or other more invasive treatments contributes to its strong market presence.
SymPeptide XLash, like many cosmetic ingredient suppliers, is increasingly focused on sustainability. 
While specific sustainability practices related to SymPeptide XLash are not always highlighted, the broader trend in the industry includes sourcing raw materials responsibly, reducing environmental impact during production, and ensuring ethical practices throughout the supply chain.

The success of SymPeptide XLash points to a growing interest in peptide-based cosmetics. 
Future developments may include more targeted peptides for specific cosmetic applications, improved delivery systems to enhance efficacy, and combinations with other innovative ingredients to address various beauty concerns.
As the beauty industry moves towards more personalized skincare and haircare solutions, ingredients like SymPeptide XLash may be integrated into customizable products, where formulations are tailored to individual needs based on factors like genetic makeup, lifestyle, and specific beauty goals.

Uses:
SymPeptide XLash is an oligomeric biosurfactant used in dermacosmetic compositions.
The most common application of SymPeptide XLash is in eyelash growth serums. 
These serums are applied directly to the lash line to stimulate the natural growth of longer, thicker, and fuller eyelashes.

The peptide works by promoting the production of keratin in the hair follicles, which strengthens and elongates the lashes over time.
Some mascaras include SymPeptide XLash as an active ingredient to not only provide the immediate effect of darker, more voluminous lashes but also to support long-term lash growth and health.
This use allows consumers to achieve both immediate cosmetic benefits and long-term improvements in lash appearance.

SymPeptide XLash can also be used in serums aimed at enhancing the thickness and fullness of eyebrows. 
Similar to its action on eyelashes, the peptide promotes hair growth in the brow area, which is particularly beneficial for individuals with sparse or thinning eyebrows.
While less common, SymPeptide XLash can be incorporated into specialized hair care products designed for the scalp to promote hair density and strength. 

This application leverages the peptide's ability to stimulate keratin production.
After the removal of eyelash extensions, lashes can sometimes appear damaged or weakened. 
Products containing SymPeptide XLash are used to help restore and strengthen natural lashes, encouraging regrowth and improving lash health.

Some anti-aging eye creams and treatments may include SymPeptide XLash to promote thicker, more youthful-looking lashes and brows as part of a comprehensive eye care regimen.
Because it is generally safe and non-irritating, SymPeptide XLash can be used in products designed for sensitive areas around the eyes, providing a targeted cosmetic enhancement without the need for invasive procedures.
SymPeptide XLash can be used in preventative lash care products aimed at maintaining the health and strength of eyelashes. 

These products can help protect lashes from breakage due to the frequent use of makeup, eyelash curlers, or environmental stressors such as pollution and UV radiation.
Besides growth serums, SymPeptide XLash can be included in lash conditioners designed to hydrate and nourish eyelashes. 
These products help to improve the overall texture and flexibility of lashes, making them less prone to brittleness and breakage.

For individuals undergoing chemotherapy, which can lead to the loss of eyelashes, SymPeptide XLash can be part of a treatment regimen aimed at supporting the regrowth of lashes after treatment. 
SymPeptide XLash may be included in products formulated to encourage the return of healthy, strong lashes during the recovery phase.
SymPeptide XLash can be used in aftercare products for eyelash tinting and perming procedures. 
These treatments can sometimes weaken the lash structure, and using a product with SymPeptide XLash can help fortify and nourish the lashes, enhancing the longevity of the treatment results.

SymPeptide XLash can be included in lash primers that are applied before mascara. 
These primers not only prepare the lashes for better mascara application but also deliver the peptide’s benefits, promoting lash growth and conditioning while extending the mascara’s effects.
SymPeptide XLash can be a key ingredient in comprehensive cosmetic kits that include serums, conditioners, and growth enhancers for both eyelashes and eyebrows. 
These kits are marketed as all-in-one solutions for individuals looking to improve the appearance and health of their lashes and brows.

SymPeptide XLash can be used in gender-neutral grooming products that cater to anyone looking to enhance their natural eyelashes and eyebrows. 
The ingredient’s benefits are universal, making it suitable for all genders who seek fuller, healthier lashes and brows.
Certain medical conditions, such as alopecia or thyroid disorders, can cause eyelash loss. 

Products containing SymPeptide XLash can be part of a treatment strategy to encourage lash regrowth in individuals affected by such conditions.
SymPeptide XLash is often included in luxury and premium beauty products due to its scientifically backed efficacy and ability to deliver visible results. 
These products are typically marketed as high-performance solutions for enhancing lash and brow appearance.

SymPeptide XLash can be included in eye creams or serums that also target dark circles, puffiness, and fine lines. 
These multi-tasking products offer both anti-aging and lash-enhancing benefits, appealing to consumers looking for comprehensive eye care.
SymPeptide XLash is recognized for its effectiveness, products containing this ingredient are often featured in beauty subscription boxes, allowing consumers to try high-quality lash enhancers as part of a curated beauty experience.

With the rise of personalized skincare and beauty, SymPeptide XLash can be formulated into customized lash serums tailored to individual needs based on factors like lash density, length, and desired outcomes.
For individuals who experience inflammation or irritation of the eyelids, SymPeptide XLash can be part of a treatment regimen to support the recovery and regrowth of healthy lashes once the underlying issue has been resolved.
SymPeptide XLash is sometimes included in professional-grade products used in beauty salons for lash treatments. 

SymPeptide XLash may offer more concentrated formulations for clients seeking enhanced results under the care of a beauty professional.
SymPeptide XLash can be used in products specifically designed for the aftercare of eyelash extensions. 
SymPeptide XLash help to maintain the health of natural lashes beneath the extensions, reducing damage and promoting regrowth once the extensions are removed.

Safety Profile:
Although SymPeptide XLash is designed to be non-irritating, some individuals may have allergic reactions or skin sensitivities to the peptide or other ingredients in the formulation. 
Symptoms might include redness, itching, swelling, or rash around the application area.
SymPeptide XLash is often recommended to perform a patch test before using a product containing SymPeptide XLash, especially for individuals with sensitive skin or a history of allergies.

SymPeptide XLash is used near the eyes, there is a risk of eye irritation if the product accidentally gets into the eyes. 
This can lead to redness, watering, stinging, or discomfort.

Users should apply the SymPeptide XLash carefully along the lash line or eyebrows to avoid direct contact with the eyes. 
In case of contact, it’s important to rinse the eyes thoroughly with water.

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