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SYNATIVE AL G 16 is a branched alcohol.
SYNATIVE AL G 16 is one of the constituent of the essential oil, extracted from the roots of Adiantum flabellulatum.
SYNATIVE AL G 16 is a long-chain glass forming monohydroxy alcohol and its dielectric relaxation at low temperature has been studied.
CAS: 2425-77-6
MF: C16H34O
MW: 242.44
EINECS: 219-370-1
Synonyms
2-HEXYL-1-DECANOL;2-Hexyldecane-1-ol;2-Hexyldecyl Alcohol;Guerbet C16;Guerbet Hexadecanol;Guerbitol 16;Isofol 16;NJCOL 160BR
SYNATIVE AL G 16 is an aliphatic alcohol.
SYNATIVE AL G 16 is a Guerbet alcohol that has excellent low temperature properties, solubility in esters and mineral oils, outstanding oxidation stability, and high additive compatibility.
SYNATIVE AL G 16 is free from human hazard and aqua toxicity labels.
SYNATIVE AL G 16 has good solubility in esters and mineral oils, high additive compatibility, foam reducing properties, and good low temperature properties.
SYNATIVE AL G 16, with the CAS number 2425-77-6, is a long-chain alcohol characterized by its hydrophobic properties due to the presence of a lengthy hydrocarbon chain.
SYNATIVE AL G 16 features a branched structure, with a hexyl group attached to the second carbon of a decanol backbone.
SYNATIVE AL G 16 is typically a colorless to pale yellow liquid at room temperature and has a relatively high boiling point, indicative of its larger molecular size.
SYNATIVE AL G 16 is soluble in organic solvents but exhibits limited solubility in water, which is common for long-chain alcohols.
SYNATIVE AL G 16 is often utilized in various applications, including as a surfactant, emulsifier, or lubricant in industrial processes.
SYNATIVE AL G 16's unique structure allows it to interact effectively with both hydrophobic and hydrophilic substances, making it valuable in formulations requiring stability and compatibility.
Additionally, SYNATIVE AL G 16 may possess mild antimicrobial properties, contributing to its use in personal care products and cosmetics.
Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.
SYNATIVE AL G 16 is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.
SYNATIVE AL G 16 has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.
SYNATIVE AL G 16 has been shown to inhibit the growth of b16 mouse melanoma cells, suggesting it may be useful for treating skin cancer.
This fatty acid also has transport properties and can form hydrogen bonds with other molecules.
SYNATIVE AL G 16 Chemical Properties
Melting point: -21--15 °C (lit.)
Boiling point: 193-197 °C/33 mmHg (lit.)
density: 0.836 g/mL at 25 °C (lit.)
vapor pressure: 0.4Pa at 148.85℃
refractive index: n20/D 1.449(lit.)
Fp: 113 °C
storage temp.: Refrigerator
solubility: Benzene (Sparingly), Chloroform (Sparingly), Methanol (Slightly)
pka: 15.08±0.10(Predicted)
form: Oil
color: Clear Colourless
Cosmetics Ingredients Functions: SKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT
InChI: 1S/C16H34O/c1-3-5-7-9-10-12-14-16(15-17)13-11-8-6-4-2/h16-17H,3-15H2,1-2H3
InChIKey: XULHFMYCBKQGEE-UHFFFAOYSA-N
LogP: 6.66 at 20℃
NIST Chemistry Reference: SYNATIVE AL G 16(2425-77-6)
EPA Substance Registry System: SYNATIVE AL G 16(2425-77-6)
Uses
A compound isolated from different parts of Lonicera japonica Thunb.
SYNATIVE AL G 16 is used in cosmetic and pharmaceutical preparations.
SYNATIVE AL G 16 may be employed as an organic solvent to study the extraction of non-polar acidic drugs from human plasma by parallel artificial liquid membrane extraction (PALME).
Synthesis
A method of preparing 2-hexyl-1-decanol (isomeric hexadecanol), the steps are as follows:
(1) 130g of n-octanol and 3.5g, 45wt% of aqueous sodium hydroxide solution were sequentially added to a 250ml three-necked flask and mixed, and then stirred at a speed of 250rpm for 8min and then warmed up to 165C, and reacted for 3h;
(2) the mixture of step (1) was cooled down to 20C afterward, and added 0.28 g zinc powder, stirring for 8min after heating to 195 , reaction 5h; and then continue to raise the temperature to 240 , reaction 30min, and then reduced to 20 ;
(3) the reaction product of step (2) to add 120g of n-heptane extraction, water washing to pH value of 6 ~ 7; control of the vacuum level is maintained at -0.096 ~ 0.098MPa, by decompression distillation, collection of 170 ~190 fraction, obtained 111.02 g colorless transparent liquid, that is, 2-hexyl-1-decanol (isomeric hexadecanol), yield 91.75%.
The WATER gel permeation chromatograph showed that the number average molecular weight of the colorless transparent liquid was 238 g/mol, Mw/Mn=1.05, and the hydroxyl content of the colorless transparent liquid was 7.15%, which was similar to the theoretical hydroxyl content of 7.02%, and it was determined that the product was isomeric hexadecanol (2-hexyl-1-decanol).
The purity of the product was 96.79% by high performance liquid chromatography (HPLC).
