TBHP (TERT-BUTYL HYDROPEROXIDE)

TBHP (Tert-butyl hydroperoxide) is a water-white liquid commonly commercially available as a 70% solution in water; 80% solutions are also available. 
TBHP (Tert-butyl hydroperoxide) is used to initiate polymerization reactions and in organic syntheses to introduce peroxy groups into the molecule.
TBHP (Tert-butyl hydroperoxide) is produced by the liquid-phase reaction of isobutane and molecular oxygen or by mixing equimolar amounts of t-butyl alcohol and 30–50% hydrogen peroxide. 

CAS Number: 75-91-2
EC Number: 200-915-7
IUPAC Name: 2-Methylpropane-2-peroxol
Chemical Formula: C4H10O2

Other names: 75-91-2, TBHP, T-Butyl hydroperoxide, tert-Butylhydroperoxide, 2-Hydroperoxy-2-methylpropane, Perbutyl H, t-Butylhydroperoxide, 1,1-Dimethylethyl hydroperoxide, Cadox TBH, Hydroperoxide, 1,1-dimethylethyl, Terc. butylhydroperoxid, tert-Butyl hydrogen peroxide, Hydroperoxyde de butyle tertiaire, Hydroperoxide, tert-butyl, Slimicide DE-488, Tertiary butyl hydroperoxide, Trigonox a-75, Trigonox A-W70, TBHP-70, 1,1-Dimethylethylhydroperoxide, Tertiary-butyl hydroperoxide, NSC 672, tert-Butyl-hydroperoxide, Caswell No. 130BB, Dimethylethyl hydroperoxide, Perbutyl H 69T, t-BuOOH, Luperox TBH 70X, terc.Butylhydroperoxid, Trigonox A-W 70, tert Butylhydroperoxide, CCRIS 5892, HSDB 837, Kayabutyl H, T-Hydro, EINECS 200-915-7, DE 488, DE-488, UNII-955VYL842B, BRN 1098280, CHEBI:64090, AI3-50541, NSC-672, 955VYL842B, Hydroperoxide, 1,1-dimethylethyl-, KAYABUTYL H 70, 2-methylpropane-2-peroxol, DTXSID9024693, EC 200-915-7, tert-Butyl Hydroperoxide (70% in Water), TERT-BUTYL HYDROPEROXIDE (II), TERT-BUTYL HYDROPEROXIDE [II], Trigonox A-75 [Czech], tBOOH, t Butylhydroperoxide, terc.Butylhydroperoxid [Czech], t Butyl Hydroperoxide, t-BHP, terc. Butylhydroperoxid [Czech], tert-Butyl Hydroperoxide (5-6 M in Decane), Hydroperoxide, t-Butyl, tert Butyl Hydroperoxide, tertiary Butylhydroperoxide, Trigonox, Hydroperoxyde de butyle tertiaire [French], tBuOOH, tert-BuOOH, Ethyldiethylperoxide, tert-Butyldioxidanyl, Perbutyl H 69, Perbutyl H 80, t-butyl-hydroperoxide, terbutyl hydroperoxide, tert-butyhydroperoxide, Terc butylhydroperoxid, tert-C4H9OOH, t-butyl hydrogenperoxide, t-butyl-hydrogenperoxide, tert.-butylhydroperoxide, tert.butyl hydroperoxide, tertiarybutylhydroperoxide, tertbutylhydrogen peroxide, t-butyl hydrogen peroxide, tert.-butyl hydroperoxide, DSSTox_CID_4693, tert-butylhydrogen peroxide, DSSTox_RID_78866, DSSTox_GSID_31209, tertiary butyl hydro peroxide, Hydroperoxide,1-dimethylethyl, Trigonox A-80 (Salt/Mix), UN 2093 (Salt/Mix), UN 2094 (Salt/Mix), USP -800 (Salt/Mix), CHEMBL348399, DTXCID504693, NSC672, tert-Butyl hydroperoxide (8CI), tert-Butyl hydroperoxide, >90% with water [Forbidden], WLN: QOX1&1&1, DTXSID60955527, 2-Methyl-prop-2-yl-hydroperoxide, Tox21_200838, Aztec t-butyl Hydroperoxide-70, Aq, MFCD00002130, BUTYL HYDROPEROXIDE (TERTIARY), TERT-BUTYL HYDROPEROXIDE [MI], AKOS000121070, TERT-BUTYL HYDROPEROXIDE [HSDB], tert-Butyl hydroperoxide, 70% in water, NCGC00090725-01, NCGC00090725-02, NCGC00090725-03, NCGC00258392-01, tert-Butyl hydroperoxide aqueous solution, Hydroperoxide, 1,1-dimethylethyl (9CI), tert-Butyl hydroperoxide, >90% with water, B3153, NS00004543, Q286326, tert-Butyl hydroperoxide solution 70 wt. % in H2O, F1905-8242, 200-915-7, Butylhydroperoxid;1,1-Dimethylethyl hydroperoxide;1,1-dimethylethyl-hydroperoxid;1,1-dimethylethylhydroperoxide;trigonoxa-75(czech);trigonoxa-w70;USP -800;T-HYDRO(R)

TBHP (Tert-butyl hydroperoxide) can also be prepared from t-butyl alcohol and 30% hydrogen peroxide in the presence of sulfuric acid or by oxidation of tert-butylmagnesium chloride. The manufacturing process of TBHP is in a closed system.
TBHP (Tert-butyl hydroperoxide) is the organic compound with the formula (CH3)3COOH. 
It is one of the most widely used hydroperoxides in a variety of oxidation processes, like the Halcon process.

TBHP (Tert-butyl hydroperoxide) is normally supplied as a 69–70% aqueous solution. 
Compared to hydrogen peroxide and organic peracids, tert-butyl hydroperoxide is less reactive and more soluble in organic solvents. 
TBHP (Tert-butyl hydroperoxide) is renowned for the convenient handling properties of its solutions. 

TBHP (Tert-butyl hydroperoxide)s solutions in organic solvents are highly stable.
TBHP (Tert-butyl hydroperoxide), also referred to by its IUPAC name 1-hydroxy-1-methylethyl hydroperoxide, is a clear, colorless to pale yellow liquid organic compound that contains a highly reactive hydroperoxide functional group (-OOH) bonded to a tert-butyl group—a branched alkyl structure derived from isobutane—which makes it a powerful and versatile chemical oxidizing agent used in a wide range of industrial and laboratory applications.

With the chemical formula C₄H₁₀O₂ and a molecular weight of approximately 90.12 g/mol, tert-butyl hydroperoxide is typically available as a concentrated solution in water or organic solvents such as decane or alcohols, due to its inherent instability and the risk of decomposition or explosion under certain conditions, particularly when exposed to heat, friction, or impurities that can act as catalysts.
Industrially, TBHP (Tert-butyl hydroperoxide) is used to prepare propylene oxide. In the Halcon process, molybdenum-based catalysts are used for this reaction: (CH3)3COOH + CH2=CHCH3 → (CH3)3COH + CH2OCHCH3

TBHP (Tert-butyl hydroperoxide) can be dehydrated to isobutene and converted to MTBE.
On a much smaller scale, tert-butyl hydroperoxide is used to produce some fine chemicals by the Sharpless epoxidation.
TBHP (Tert-butyl hydroperoxide) is potentially dangerous, but explosions are rare.

A solution of tert-butyl hydroperoxide and water with a concentration of greater than 90% is forbidden to be shipped according to US Department of Transportation Hazardous Materials Table 49 CFR 172.101.
In some sources it also has an NFPA 704 rating of 4 for health, 4 for flammability, 4 for reactivity and is a potent oxidant, however other sources claim lower ratings of 3-2-2 or 1-4-4.

TBHP (Tert-butyl hydroperoxide) is an alkyl hydroperoxide in which the alkyl group is tert-butyl.
TBHP (Tert-butyl hydroperoxide) is widely used in a variety of oxidation processes.
TBHP (Tert-butyl hydroperoxide) has a role as an antibacterial agent and an oxidising agent.

TBHP (Tert-butyl hydroperoxide) is a water-white liquid commonly commercially available as a 70% solution in water; 80% solutions are also available.
TBHP (Tert-butyl hydroperoxide) is used to initiate polymerization reactions and in organic syntheses to introduce peroxy groups into the molecule.
TBHP (Tert-butyl hydroperoxide) vapor can burn in the absence of air and may be ammable at either elevated temperature or at reduced pressure.

Fine mist/spray may be combustible at temperatures below the normal ash point.
When evaporated, the residual liquid will concentrate TBHP (Tert-butyl hydroperoxide) content and may reach an explosive concentration (＞90%).
Because of the presence of the peroxide bond (-O-O-), TBHP (Tert-butyl hydroperoxide) is classified as a reactive and potentially hazardous organic peroxide, meaning it can decompose exothermically and release oxygen in a highly energetic reaction, which makes it both valuable as a radical initiator in polymerization processes and dangerous if not stored and handled properly in accordance with stringent chemical safety protocols.

In organic synthesis and industrial chemistry, TBHP (Tert-butyl hydroperoxide) is widely employed as a selective oxidizing agent in a variety of oxidation reactions, including the epoxidation of alkenes, the oxidation of sulfides to sulfoxides, and the Baeyer–Villiger oxidation of ketones to esters or lactones, where it offers both high reactivity and functional group tolerance, often under mild conditions.
TBHP (Tert-butyl hydroperoxide) is also used as an initiator for polymerization reactions, particularly in the production of certain plastics and resins, where it decomposes to form free radicals that start chain reactions, making it crucial in the manufacture of acrylics, styrenics, and vinyl-based polymers.

Due to its reactive nature, TBHP (Tert-butyl hydroperoxide) must be stored in tightly sealed containers away from direct sunlight, heat sources, and incompatible substances such as strong acids, reducing agents, and transition metal salts, which could accelerate its decomposition and potentially lead to fire or explosion hazards.
Even in small quantities, contact with TBHP can cause severe skin and eye irritation, and inhalation of its vapors or aerosols may result in respiratory tract irritation, coughing, or dizziness, which is why proper personal protective equipment (PPE) including gloves, goggles, and fume hoods is necessary during any handling or transfer operation.

In regulatory terms, TBHP (Tert-butyl hydroperoxide) is considered a hazardous substance under the Globally Harmonized System (GHS), and it often carries hazard pictograms for oxidizing liquids, corrosive effects, and acute toxicity, with transportation regulated under UN number 3109 or UN 2014, depending on concentration and formulation.
TBHP (Tert-butyl hydroperoxide) is an organic compound consisting of a peroxide group bonded to two tert-butyl groups. 
It is one of the most stable organic peroxides, due to the tert-butyl groups being bulky. 

TBHP (Tert-butyl hydroperoxide) is a colorless liquid.
The peroxide bond undergoes homolysis at temperatures above 100 °C. 
For this reason di-tert-butyl peroxide is commonly used as a radical initiator in organic synthesis and polymer chemistry. 

The decomposition reaction proceeds via the generation of methyl radicals.
(CH3)3COOC(CH3)3 → 2 (CH3)3CO• (CH3)3CO• → (CH3)2CO + CH•32 CH•3 → C2H6
TBHP (Tert-butyl hydroperoxide) can in principle be used in engines where oxygen is limited, since the molecule supplies both the oxidizer and the fuel.

TBHP (Tert-butyl hydroperoxide) is the organic compound with the formula (CH3)3COOH. 
It is one of the most widely used hydroperoxides in a variety of oxidation processes, like the Halcon process. 
TBHP (Tert-butyl hydroperoxide) is normally supplied as a 69–70% aqueous solution. 

Compared to hydrogen peroxide and organic peracids, tert-butyl hydroperoxide is less reactive and more soluble in organic solvents. 
TBHP (Tert-butyl hydroperoxide) is renowned for the convenient handling properties of its solutions. 
Its solutions in organic solvents are highly stable.

Because of its strong oxidative capabilities and controlled reactivity, TBHP (Tert-butyl hydroperoxide) is often preferred over other peroxides in laboratory synthesis and industrial-scale reactions, particularly when cleaner reaction profiles, fewer side products, or enhanced selectivity are required, especially in the production of fine chemicals and pharmaceutical intermediates.
Unlike hydrogen peroxide, which is miscible in water and tends to react aggressively with a broader range of substances, TBHP (Tert-butyl hydroperoxide)’s structure—with a bulky tert-butyl group—allows for more regulated reactivity, making it suitable for metal-catalyzed oxidations involving molybdenum, vanadium, or titanium complexes, which can yield high-purity products under controlled temperature and pressure conditions.
In petroleum refining and petrochemical processes, TBHP (Tert-butyl hydroperoxide) is sometimes used as a co-catalyst or initiator in the oxidative cleavage of hydrocarbons and olefins, facilitating transformations that are otherwise difficult to achieve with traditional oxidants, and this contributes to its value in applications such as the synthesis of propylene oxide, glycols, and ethers.

Melting point: -2.8 °C
Boiling point: 37 °C (15 mmHg)
Density: 0.937 g/mL at 20 °C
vapor pressure: 62 mmHg at 45 °C
refractive index: n20/D 1.403

Flash point: 85 °F
storage temp.: 2-8°C
pka: pK1: 12.80 (25°C)
form: Liquid
color: Clear colorless
PH: 4.3

Water Solubility: Miscible
Merck: 14,1570
BRN: 1098280
Exposure limits: No exposure limit is set. On the basis of its irritant properties, a ceiling limit of 1.2 mg/m3 (0.3 ppm) is recommended.

Stability: Stable, but may explode if heated under confinement.
Decomposition may be accelerated by traces of metals, molecular sieve or other contaminants. Incompatible with reducing agents, combustible material, acids.
InChIKey: CIHOLLKRGTVIJN-UHFFFAOYSA-N
LogP: 1.230 (est)

TBHP (Tert-butyl hydroperoxide) can be synthesized by reacting tert-butanol with hydrogen peroxide in the presence of an acid catalyst, the industrial production and handling of TBHP is carefully regulated, as the substance is sensitive to shock, heat, and contamination, all of which can lead to rapid decomposition, gas evolution, and potential combustion, requiring specialized transport protocols including temperature-controlled containers and stabilizing additives.
From a toxicological standpoint, TBHP (Tert-butyl hydroperoxide) exhibits moderate acute toxicity if ingested, inhaled, or absorbed through the skin, and exposure may result in symptoms ranging from headache, nausea, and respiratory discomfort to more severe effects such as chemical burns, central nervous system depression, or organ toxicity, especially in poorly ventilated spaces or when used without appropriate safety controls.

In the case of fire, TBHP (Tert-butyl hydroperoxide) does not merely serve as fuel but also acts as a source of oxygen, feeding flames and accelerating combustion, which means that water alone may be insufficient for extinguishment, and trained personnel should use foam, carbon dioxide, or dry chemical extinguishers, along with full protective gear and self-contained breathing apparatus (SCBA) due to the release of toxic vapors such as tert-butanol, acetic acid, or various aldehydes.
Environmental release of TBHP (Tert-butyl hydroperoxide)—whether through spills, leaks, or improper disposal—poses a risk to aquatic life because its oxidative nature can damage or disrupt biological membranes, enzymes, and reproductive cycles in fish and other waterborne organisms, prompting regulatory agencies to recommend containment procedures, neutralization protocols, and waste treatment technologies in compliance with local environmental protection standards.

Storage of TBHP (Tert-butyl hydroperoxide) must take into account not only temperature control (typically below 30 °C) but also container material compatibility, as it may degrade plastics like polyethylene over time, corrode metal surfaces, or permeate rubber gaskets, and thus manufacturers often supply TBHP (Tert-butyl hydroperoxide) in amber glass bottles or high-grade stainless steel drums with secondary containment systems to minimize risk.
Despite its hazards, when handled with proper precautions and technical knowledge, tert-butyl hydroperoxide remains a crucial reagent in green chemistry and industrial oxidation strategies, offering chemists and engineers a powerful tool to drive reactions efficiently without resorting to heavy metal oxidants or environmentally persistent byproducts.

TBHP (Tert-butyl hydroperoxide) is an alkyl hydroperoxide in which the alkyl group is tert-butyl. 
It is widely used in a variety of oxidation processes. 
It has a role as an antibacterial agent and an oxidising agent.

TBHP (Tert-butyl hydroperoxide) should be stored in the dark at room temperature (do not refrigerate) separately from oxidizable compounds, flammable substances, and acids. 
Reactions involving this substance should be carried out behind a safety shield.
TBHP (Tert-butyl hydroperoxide) and concentrated aqueous solutions of TBHP react violently with traces of acid and the salts of certain metals, including, in particular, manganese, iron, and cobalt. 

Mixing anhydrous tert-butyl hydroperoxide with organic and readily oxidized substances can cause ignition and explosion. 
TBHP (Tert-butyl hydroperoxide) can initiate polymerization of certain olefins.
Excess tert-butyl hydroperoxide and waste material containing this substance should be placed in an appropriate container, clearly labeled, and handled according to your institution's waste disposal guidelines.

TBHP (Tert-butyl hydroperoxide) is an organic peroxide widely used in a variety of oxidation processes. 
Watery odorless colorless liquid.
Floats and mixes slowly with water.

TBHP (Tert-butyl hydroperoxide) is the organic compound with the formula (CH3)3COOH.
TBHP (Tert-butyl hydroperoxide) is one of the most widely used hydroperoxides in a variety of oxidation processes, for example the Halcon process.
TBHP (Tert-butyl hydroperoxide) is normally supplied as a 69–70% aqueous solution.

Compared to hydrogen peroxide and organic peracids, TBHP (Tert-butyl hydroperoxide) is less reactive and more soluble in organic solvents.
Overall, TBHP (Tert-butyl hydroperoxide) is renowned for the convenient handling properties of its solutions.
TBHP (Tert-butyl hydroperoxide)'s solutions in organic solvents are highly stable.

TBHP (Tert-butyl hydroperoxide), referred to as TBHP, is one of the most commonly used alkyl hydroperoxide.
Commodities are generally light yellow transparent non-volatile liquids, slightly soluble in water, miscible with organic solvents.
TBHP (Tert-butyl hydroperoxide) is mainly used as an initiator for free radical reactions or polymerization reactions in industry.

Compared with the decomposition products of most other initiators, TBHP (Tert-butyl hydroperoxide) is acidic.
The decomposition products of TTBHP (Tert-butyl hydroperoxide) and a small amount of acetone, which are not corrosive to the equipment, so the requirements for the equipment are not high.
The decomposition activation energy of O-O bond in TBHP (Tert-butyl hydroperoxide) is low, which can be used as an improver to improve the decane number of diesel oil.

TBHP (Tert-butyl hydroperoxide) is a very important organic synthesis intermediate.
TBHP (Tert-butyl hydroperoxide) is a crosslinking agent used in unsaturated polyester crosslinking under medium and high temperature conditions.

Uses Of TBHP (Tert-butyl hydroperoxide):
TBHP (Tert-butyl hydroperoxide) is an intermediate in the production of propylene oxide and t-butyl alcohol from isobutane and propylene. 
TBHP (Tert-butyl hydroperoxide) is primarily used as an initiator and finishing catalyst in the solution and emulsion polymerization methods for polystyrene and polyacrylates. 
Other uses are for the polymerization of vinyl chloride and vinyl acetate and as an oxidation and sulfonation catalyst in bleaching and deodorizing operations. 

TBHP (Tert-butyl hydroperoxide) is a strong oxidant and reacts violently with combustible and reducing materials, and metallic and sulfur compounds.
TBHP (Tert-butyl hydroperoxide) is used as an initiator for radical polymerization and in various oxidation process such as sharpless epoxidation. 
It is involved in osmium catalyzed vicinal hydroxylation of olefins under alkaline conditions. 

TBHP (Tert-butyl hydroperoxide) is used in catalytic asymmetric oxidation of sulfides to sulfoxides using binaphthol as a chiral auxiliary and in the oxidation of dibenzothiophenes. 
TBHP (Tert-butyl hydroperoxide) plays an important role for the introduction of peroxy groups in organic synthesis.
In organic synthesis, TBHP (Tert-butyl hydroperoxide) serves as a highly effective oxidizing agent, particularly in selective oxidation reactions, where it can oxidize a wide range of organic substrates without the need for harsh conditions or toxic metals. 

TBHP (Tert-butyl hydroperoxide) is utilized in the epoxidation of alkenes, where it reacts with unsaturated compounds to form epoxides—key intermediates in the synthesis of fine chemicals, pharmaceuticals, and agrochemicals. 
TBHP (Tert-butyl hydroperoxide) is also employed in the oxidation of sulfides to sulfoxides, which is a critical step in the production of certain pharmaceutical drugs and flavoring agents. 
Furthermore, it is a vital reagent in the Baeyer-Villiger oxidation, where it facilitates the conversion of ketones into esters or lactones, which are widely used in fragrance and flavor industries.

TBHP (Tert-butyl hydroperoxide) plays an increasingly important role in green chemistry and environmentally-friendly processes, where it is used to replace more hazardous reagents and reduce environmental impact. 
TBHP (Tert-butyl hydroperoxide) is utilized in biodegradable chemical processes to perform selective oxidation reactions in aqueous environments, making it suitable for water-based formulations and reducing the reliance on toxic solvents. 
Moreover, its mild oxidative nature and ability to decompose into non-toxic byproducts makes it an attractive option for environmental cleanup operations, such as oxidizing organic pollutants in contaminated soil and water, providing an alternative to more toxic and non-selective methods.

TBHP (Tert-butyl hydroperoxide) is an intermediate in the production of propylene oxide and t-butyl alcohol from isobutane and propylene.
TBHP (Tert-butyl hydroperoxide) is primarily used as an initiator and nishing catalyst in the solution and emulsion polymerization methods for polystyrene and polyacrylates.
Other uses are for the polymerization of vinyl chloride and vinyl acetate and as an oxidation and sulfonation catalyst in bleaching and deodorizing operations.

TBHP (Tert-butyl hydroperoxide) is a strong oxidant and reacts violently with combustible and reducing materials, and metallic and sulfur compounds.
TBHP (Tert-butyl hydroperoxide) is used as an initiator for radical polymerization and in various oxidation process such as sharpless epoxidation.
TBHP (Tert-butyl hydroperoxide) is involved in osmium catalyzed vicinal hydroxylation of olens under alkaline conditions.

Furthermore, TBHP (Tert-butyl hydroperoxide) is used in catalytic asymmetric oxidation of suldes to sulfoxides using binaphthol as a chiral auxiliary and in the oxidation of dibenzothiophenes.
TBHP (Tert-butyl hydroperoxide) plays an important role for the introduction of peroxy groups in organic synthesis.
Industrially, TBHP (Tert-butyl hydroperoxide) is used to prepare propylene oxide.

In the Halcon process, molybdenum-based catalysts are used for this reaction: (CH3)3COOH + CH2=CHCH3 → (CH3)3COH + CH2OCHCH3
Interestingly, TBHP (Tert-butyl hydroperoxide) is also used in explosives chemistry—specifically in the manufacture of energetic materials and the study of explosive decomposition reactions. 
Although TBHP (Tert-butyl hydroperoxide) itself is not considered an explosive material, it can be involved in initiating explosive reactions or used to synthesize compounds with high energy release potential, often in the military or defense sectors. 

This application requires a high degree of caution and specific safety protocols due to the potential hazards associated with the compound’s instability under extreme conditions.
One of the most prominent and widely recognized uses of TBHP (Tert-butyl hydroperoxide) is as an initiator for free radical polymerization reactions. 
It is used in the production of various types of synthetic polymers and plastics, including polystyrene, acrylics, polyvinyl chloride (PVC), and polymethyl methacrylate (PMMA), where it decomposes to form free radicals that initiate the polymerization of monomers, leading to the formation of long polymer chains. 

This application is especially valued in industries where controlled polymerization with consistent molecular weight and desired properties is essential, such as in the production of high-performance resins used in coatings, adhesives, and composites.
Another important use of tert-butyl hydroperoxide is in polymer crosslinking, where it is used to introduce chemical links between polymer chains. 
This process improves the mechanical properties, heat resistance, and chemical stability of the resulting materials. 

TBHP (Tert-butyl hydroperoxide) is frequently employed in the production of crosslinked polyethylene (PEX), which is widely used in plumbing, electrical wiring, and medical devices due to its enhanced resistance to temperature and pressure. 
The crosslinking process involves the formation of free radicals that induce the creation of covalent bonds between polymer chains, significantly improving the physical properties of the polymer material.
In the fine chemicals industry, TBHP (Tert-butyl hydroperoxide) is used in a variety of reactions to synthesize important chemical intermediates that are later used in the manufacture of more complex compounds. 

One key example is its use in the synthesis of tert-butyl alcohol, an important solvent and chemical intermediate, where TBHP (Tert-butyl hydroperoxide) reacts with isobutene under mild conditions to produce the alcohol. 
Similarly, TBHP (Tert-butyl hydroperoxide) is involved in the preparation of hydroperoxides that serve as starting materials in the synthesis of antioxidants, pharmaceutical compounds, and agricultural chemicals, where precise oxidation control is required.

In the laboratory setting, TBHP (Tert-butyl hydroperoxide) is a versatile reagent used in a variety of research applications, particularly in the synthesis of radicals and the exploration of radical chemistry. 
It is employed as a source of radicals in mechanistic studies and to initiate reactions in chemical research where controlled oxidation is required. 
TBHP (Tert-butyl hydroperoxide) is used to investigate radical mechanisms in synthetic organic chemistry, including the formation of C–C bonds in radical coupling reactions, as well as in the study of radical-induced polymerization and other advanced materials synthesis. 

TBHP (Tert-butyl hydroperoxide) is also used as a reagent for investigating the role of radicals in biological systems, particularly in oxidative stress studies.
On an industrial scale, TBHP (Tert-butyl hydroperoxide) is often used in the synthesis of high-value specialty chemicals, where its controlled oxidation properties are essential. 
For example, it is used in the production of specific types of high-purity aldehydes, ketones, and organic acids that are important as intermediates in the manufacture of pharmaceuticals, agrochemicals, and cosmetic ingredients. 

TBHP (Tert-butyl hydroperoxide)s ability to selectively oxidize compounds under mild conditions ensures that these reactions are carried out with high selectivity and yield, minimizing the formation of byproducts and improving the overall cost-effectiveness of production processes.
TBHP (Tert-butyl hydroperoxide) is widely used in a variety of radical-based industrial applications, particularly in the production of high-performance rubbers and elastomers. 
In these applications, it is employed as an initiator for crosslinking reactions in synthetic rubber compounds, which improves the rubber’s resilience, elasticity, and long-term durability. 

These rubber products are commonly used in the manufacture of automotive tires, conveyor belts, and medical devices, where their performance under stress and temperature fluctuations is crucial.
TBHP (Tert-butyl hydroperoxide) used as a catalyst for polymerization reactions.
TBHP (Tert-butyl hydroperoxide) used as an introducer of peroxide groups in the substituent reaction.

TBHP (Tert-butyl hydroperoxide) is a rst-class organic oxidant, which is easy to explode at high temperatures.
TBHP (Tert-butyl hydroperoxide) is used for dyeing and printing cotton, viscose, silk, cotton ber and other bers and their fabrics, and also for dyeing polyester/viscose blended fabrics.
TBHP (Tert-butyl hydroperoxide) can be used alone or for color matching.

After dyeing viscose fabric, TBHP (Tert-butyl hydroperoxide) is treated with xing agent M, and the color light is slightly wilted.
After xing agent Y treatment, the color light is slightly blue, and after urea-formaldehyde resin nishing, the color light is bluer.
TBHP (Tert-butyl hydroperoxide) used as desiccant, polymerization initiator, organic synthesis intermediate for unsaturated melamine resin coatings

Safety Profile:
Moderately toxic by ingestion and inhalation. 
A severe skin and eye irritant. 
Mutation data reported at highest dosage levels, symptoms noted were severe depression, incoordmation, and cyanosis. 

Death was due to respiratory arrest very dangerous fire hazard when exposed to heat or flame, or by spontaneous chemical reaction such as with reducing materials. 
Moderately explosive; may explode during distillation. 
Violent reaction with traces of acid. 

Concentrated solutions may ignite spontaneously on contact with molecular sieve. 
Mixtures with transition metal salts may react vigorously and release oxygen. 
Forms an unstable solution with 1,2-dichloroethane. 

To fight fire, use alcohol foam, CO2, dry chemical when heated to decomposition it emits acrid smoke and fumes.
TBHP (Tert-butyl hydroperoxide) is a flammable liquid and a highly reactive oxidizing agent. 
Pure TBHP (Tert-butyl hydroperoxide) is shock sensitive and may explode on heating. 

Carbon dioxide or dry chemical extinguishers should be used for fires involving tert-butyl hydroperoxide.
TBHP (Tert-butyl hydroperoxide) is an irritant to the nose, eyes, and skin. 
TBHP (Tert-butyl hydroperoxide) is also flammable, and can explode unpredictably at high (≈150 °C) temperatures.

TBHP (Tert-butyl hydroperoxide) is a highly reactive compound, and one of its most significant hazards lies in its tendency to decompose exothermically, especially when exposed to heat, shock, or friction. 
The decomposition reaction releases oxygen and generates heat, creating the potential for violent explosions or the spontaneous ignition of nearby materials. 
In particular, if TBHP (Tert-butyl hydroperoxide) is stored improperly or exposed to incompatible substances, such as strong acids, alkalis, or metal salts, it can undergo rapid decomposition, causing a release of toxic gases and posing significant risks to both human health and property. 

Therefore, careful attention must be paid to its storage and handling conditions, ensuring that it is kept in temperature-controlled, stable environments and that contamination is avoided.
Due to its oxidizing nature, TBHP (Tert-butyl hydroperoxide) can significantly accelerate combustion, acting as an oxidizer in fire scenarios. 
This property makes it particularly dangerous in the presence of flammable materials or organic solvents, as it can increase the intensity of fires and make firefighting efforts more difficult. 

TBHP (Tert-butyl hydroperoxide) itself is not highly flammable but can enhance the spread of flames, and in confined spaces or enclosed environments, it may lead to explosions or flash fires if exposed to heat or sparks. 
The exothermic decomposition of TBHP (Tert-butyl hydroperoxide) can be triggered by high temperatures, which means that storage areas must be ventilated and kept below recommended temperature thresholds to avoid unsafe reactions.