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Tergitol np-4 can be used in oilfield drilling and production formulations, dispersant for petroleum oil, in-process cleaning, cleaners and degreasers, and dry cleaning.
Tergitol np-4 Surfactant is a nonionic surfactant for use in cleaners and degreasers, dry cleaning, agrochemicals and adhesives; functioning as a wetting agent, stabilizer, an excellent emulsifier and couples detergent range nonionics into hydrocarbon systems.
Tergitol np-4 is a non-ionic surfactant.
CAS Number: 127087-87-0
Molecular Formula: C17H28O2
Molecular Weight: 264.40302
EINECS Number: 500-315-8
Synonyms: 7311-27-5, Ethanol, 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]-, 2-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol, 2-(2-(2-(2-(4-Nonylphenoxy)ethoxy)ethoxy)ethoxy)ethanol, Tetraethylene glycol mono(p-nonylphenyl) ether, 4-nonylphenol tetraethoxylate, Nonoxynol-4, Ethanol, 2-(2-(2-(2-(4-nonylphenoxy)ethoxy)ethoxy)ethoxy)-, Nonoxynol 4, Tergitol np-4, Norfox np-4, EINECS 230-770-5, NONOXINOL 4, NPEO4, Nonylphenol-4-ethoxylate, PEG-4 Nonyl phenyl ether, P-nonylphenol tetraethoxylate, CHEMBL2107128, DTXSID0064624, SCHEMBL10705426, UTXPMECBRCEYCI-UHFFFAOYSA-N, DB-286834, NS00013900, 2-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy] ethanol, Ethanol, 2-(2-(2-(2-(p-nonylphenoxy)ethoxy)ethoxy)ethoxy)-, 2-ethanediyl),alpha-(4-nonylphenyl)-omega-hydroxy-poly(oxy-branched,2-ethanediyl)-poly(oxy-alpha-(4-nonylphenyl)-omega-hydroxy-poly(oxy-branched,nonyl phenoxypolyethoxylethanol,Tergitol NP-9 (NPE) Solution,Tergitol(R) NP-10,TergitolPOLYETHYLENE GLYCOL TRIMETHYLNONYL ETHER,FREE SAMPLE NCV TERGITAL TM NP 10 SURFACTANT,Poly(oxy,1,2-ethanediyl) α-(4-nonylphenyl)-omega-hydroxy- branched
Tergitol np-4 macoromolecule comprising a branched nonyl group bonded to one of the ring positions in 2-[phenoxypoly(ethoxy)]ethanol.
A commericially available detergent, it is used to help crystallise proteins and extract the cytoplasmic contents of cellula culture.
Excellent oil-soluble surfactant with excellent emulsification properties at low HLB.
Tergitol np-4 is highly water-soluble emulsier & stabilizer.
Tergitol np-4 is used in cleaners & detergents, paper & textile processing, paints & coatings, agrochemicals.
Tergitol np-4 has been used in a study to quantify the volumetric mass transfer coecient and liquid lm coecient using a dynamic surface tension measurement.
Tergitol np-4 has also been used in a study to investigate the use of surfactant solutions and colloidal gas aphron to remove naphthalene from a contaminated soil matrix.
Tergitol np-4, Surfactant is a Nonylphenol Ethoxylate surfactant.
It is nonionic and provides excellent detergency, outstanding wetting, versatile solubility characteristics and low odor.
Tergitol np-4 is suggested for use in cleaners & degreasers, prewash spotters and oil field chemicals.
Tergitol np-4 is a commercially available detergent with CAS Registry Number 9016-45-9.
Tergitol np-4 is an ethoxylated nonylphenol for non-ionic surfactants and can act as emulsifier and demulsifier agent.
Tergitol np-4 is often used to break open all membranes within a cell, including the nuclear membrane.
To break only the cytoplasmic membrane, other detergents such as digitonin can be used.
Tergitol np-4 has applications in paper and textile processing, in paints and coatings, and in agrochemical manufacturing.
Care should be taken to avoid confusing Tergitol np-4 which is currently out of production.
Tergitol np-4 was originally manufactured and trademarked by the Shell Chemical Company, but was phased out of production in the early 2000s.
Confusingly, biochemical protocols published between the 1960s and 2000s refer to Shell's Tergitol np-4.
Shell's original Tergitol np-4 had a hydrophilic-lipophilic balance (HLB) value of 13.5, as opposed to 12.9 for the currently available IGEPAL CA-630, indicating that the currently available compound is more potent than the compound used in older publications.
Indeed, according to a 2017 report,[6] an additional dilution factor of 10 was required for the currently available NP-40 ("Nonidet P-40 substitutes") to match the activity of the previously available, and now discontinued, Shell's Nonidet P-40.
Tergitol np-4 is a nonionic surfactant belonging to the alkylphenol ethoxylates (APEs) group.
It is specifically a nonylphenol ethoxylate (NPEO) with four ethylene oxide units in its structure.
Contains a hydrophobic nonylphenol group attached to a hydrophilic chain of four ethylene oxide (EO) units.
Clear to slightly yellow liquid or waxy solid, depending on temperature.
Tergitol np-4 soluble in water and organic solvents.
Lowers the surface tension of water, making it an effective surfactant.
Tergitol np-4 is used in detergents and cleaning formulations for industrial applications due to its ability to emulsify oils and disperse soils.
Acts as an emulsifier and wetting agent in pesticide formulations.
Tergitol np-4 improves dispersion of pigments and provides stability in formulations.
Tergitol np-4 utilized as a scouring agent, wetting agent, and emulsifier in textile treatments.
Found in some formulations as a mild surfactant, though less commonly used in consumer products due to environmental concerns.
Tergitol np-4 is used in drilling fluids and enhanced oil recovery due to its emulsifying properties.
Moderately toxic to aquatic life; can bioaccumulate in organisms.
Prolonged exposure may cause skin and eye irritation.
Nonylphenol ethoxylates, including Tergitol np-4, degrade to nonylphenol, which is a known endocrine disruptor.
The use of NPEOs, including Tergitol NP-4, is restricted or phased out in many regions (e.g., the EU and Canada) due to their persistence, bioaccumulation, and environmental toxicity.
Tergitol np-4 wear gloves and goggles when handling concentrated formulations.
Keep in a cool, well-ventilated area away from strong oxidizers.
Tergitol np-4 dispose of according to local environmental regulations to minimize contamination risks.
Tergitol np-4 is used in de-inking processes and as a wetting and dispersing agent.
Enhances the stability and performance of adhesive formulations.
Acts as an emulsifier in metalworking fluids, providing lubrication and cooling properties.
Stabilizes emulsions in latex and rubber production processes.
Tergitol np-4 sometimes used in hard-surface cleaners and degreasers for its grease-cutting ability.
Tergitol np-4 s used in concrete additives and as a defoaming or wetting agent.
Occasionally used in formulations to break down oil slicks into smaller droplets for easier biodegradation.
Tergitol np-4 breaks down into nonylphenol (NP), a persistent organic pollutant.
Tergitol np-4 is resistant to biodegradation and accumulates in water bodies and sediments.
Known to cause endocrine disruption in aquatic organisms, leading to reproductive and developmental abnormalities.
Can bioaccumulate in fish and other organisms, posing risks to higher levels of the food chain.
Banned or restricted in several countries under the Stockholm Convention and local environmental laws.
Alternatives such as alcohol ethoxylates (AEs) are being promoted.
Tergitol np-4 exposure to NP (its degradation product) is associated with interference in hormonal systems.
While not definitively classified as a carcinogen, chronic exposure to related compounds raises concerns.
Tergitol np-4 avoid direct skin and eye contact; use PPE such as gloves, goggles, and aprons.
Ensure adequate ventilation when working with liquid or aerosol forms.
Store in tightly sealed containers in a dry, cool, and well-ventilated area.
Keep away from heat sources, oxidizers, and incompatible materials like strong acids.
Tergitol np-4 absorb spills with inert materials like sand or vermiculite.
Boiling point: 188.6℃[at 101 325 Pa]
Density: 1.04 g/mL at 20 °C
vapor pressure: 0Pa at 25℃
refractive index: n20/D 1.491(lit.)
Flash point: >230 °F
storage temp.: Store at RT.
solubility: Chloroform (Slightly), Methanol (Sparingly), Water (Sparingly)
form: Oil to Thick Oil
color: Colourless
Water Solubility: 1.104mg/L at 25℃
LogP: 5.669 at 25℃
Tergitol np-4 is a commercially available detergent .
Tergitol np-4 is an ethoxylated nonylphenol for non-ionic surfactants and can act as emulsier and demulsier agent.
Tergitol np-4 is often used to break open all membranes within a cell, including the nuclear membrane.
To break only the cytoplasmic membrane, other detergents such as IGEPAL CA-630 can be used.
Tergitol np-4 has applications in paper and textile processing, in paints and coatings, and in agrochemical manufacturing.
Care should be taken to avoid confusing Tergitol NP-40 with Nonidet P-40 (octyl phenoxypolyethoxylethanol) which is currently out of production.
Nonidet P-40 ("Non-Ionic Detergent") was originally manufactured and trademarked by the Shell Chemical Company, but was phased out of production in the early 2000s.
Confusingly, biochemical protocols published between the 1960s and 2000s refer to Shell's Nonidet P-40 as Tergitol NP-40.
Shell's original Nonidet P-40 had a hydrophilic-lipophilic balance (HLB) value of 13.5, as opposed to 12.9 for the currently available
Tergitol np-4, indicating that the currently available compound is more potent than the compound used in older publications.
Indeed, according to a 2017 report, an additional dilution factor of 10 was required for the currently available Tergitol np-4 to match the activity of the previously available, and now discontinued, Shell's Nonidet P-40.
Tergitol np-4 Br Substitute (NP-40 alternative) is used as nonionic surface-active agent.
Tergitol np-4 is an eective emulsier for solvents such as xylene.
Furthermore in Biochemistry, Tergitol np-4 is a nonionic surfactant used in the isolation of membrane complexes.
Due to its nonionic structure, this product is compatible with anionic surfactants and is stable in the presence of acids, bases, and salts.
Tergitol np-4 should not be mixed with concentrated oxidizing or reducing agents since the mixture of these compounds with organic compounds could form a potentially explosive mixture.
Tergitol NP-40: a nonionic, non-denaturing detergent, octylphenoxypolyethoxyethanol, made by Shell Chemical Co., and later by Sigma-Aldrich, though it was taken o the market in the early-2000s.
Tergitol NP-40 was often abbreviated "NP-40," including by Sigma-Aldrich on the label, but it should not be confused with Dow Chemical's Tergitol "NP-40," which is used to break open cell and nuclear membranes.
The Tergitol NP-40 molecule contains a total of 54 atom(s).
There are 32 Hydrogen atom(s), 19 Carbon atom(s) and 3 Oxygen atom(s).
A chemical formula of Tergitol NP-40 can therefore be written as: C19H32O3
The chemical formula of Tergitol np-4 shown above is based on the molecular formula indicating the numbers of each type of atom in a molecule without structural information, which is dierent from the empirical formula which provides the numerical proportions of atoms of each type
Tergitol np-4, Surfactant is a Nonylphenol Ethoxylate surfactant.
It is nonionic and provides excellent detergency, outstanding wetting, versatile solubility characteristics and low odor.
Tergitol np-4 is suggested for use in cleaners & degreasers, prewash spotters and oil field chemicals.
Tergitol np-4 is a Surfactant.
Excellent oil-soluble surfactant with excellent emulsification properties at low HLB.
Tergitol np-4 can be used in oilfield drilling and production formulations, dispersant for petroleum oil, in-process cleaning, cleaners and degreasers, and dry cleaning.
Tergitol np-4 is a Nonylphenol Ethoxylate surfactant.
It is non-ionic and provides excellent detergency, rinseability, and low odor.
Tergitol np-4 is suggested for use in cleaners & degreasers, pre-wash spotters and metal-working fluids.
Uses:
Tergitol np-4, branched is a surfactant and emulsifying agent.
It is used as a non-ionic surface-active agent and as a dispersing agent in cosmetics.
Tergitol np-4 has been used in a study to assess the structural characterization and antimicrobial properties of silver nanoparticles.
It has also been used in a study to investigate the detection of Salmonella enterica serotype enteritidis in naturally contaminated environmental samples from integrated poultry houses.
Tergitol np-4 has been used in a study to quantify the volumetric mass transfer coecient and liquid lm coecient using a dynamic surface tension measurement.
Tergitol np-4 has also been used in a study to investigate the use of surfactant solutions and colloidal gas aphron to remove naphthalene from a contaminated soil matrix.
Tergitol np-4 is a Nonylphenol Ethoxylate surfactant.
Tergitol np-4 is non-ionic and provides excellent detergency, outstanding wetting, versatile solubility characteristics and low odor.
Tergitol np-4 is suggested for use in paper & textile processing, paints & coatings and agrochemicals.
Used as analytical standard for environmental analysis.
ISO/CD 18857-2 (International Organization for Standardization, Geneva) describes a new international standard method for the determination of octylphenol, nonylphenol, their mono- and diethyoxylates, and bisphenol A in nonltered samples of drinking, groundwater, surface water, and wastewater.
Tergitol np-4 is an organic compound, widely used as a component or solvent for nitrocellulose and in a variety of dyes, inks, cleaning agents, resins, paints, varnishes, etc.
Tergitol np-4 is also used for increasing the stability of emulsions.
Tergitol np-4 may be used as an extraction solvent for the quantication and analysis of algal lipids from algae samples using normalphase high performance liquid chromatography(HPLC) coupled in parallel to an evaporative light scattering detector (ELSD) and quadrupole mass spectrometer(QMS).
Refer to the product′s Certicate of Analysis for more information on a suitable instrument technique.
Contact Technical Service for further support.
Tergitol np-4 is used in formulations for heavy-duty cleaners and degreasers.
Effective in removing grease, oils, and soils from surfaces in industrial settings.
Tergitol np-4 acts as an emulsifier and wetting agent in pesticide and herbicide formulations.
Ensures even spreading and penetration of agricultural chemicals on plants.
Tergitol np-4 is used as a scouring agent to remove impurities from fabrics.
Functions as a wetting agent and emulsifier in dyeing and finishing processes.
Tergitol np-4 enhances pigment dispersion and stability in paint formulations.
Reduces surface tension to improve flow and leveling during application.
Tergitol np-4 improves stability and performance by acting as an emulsifier in adhesive formulations.
Tergitol np-4 is used in drilling fluids to emulsify oils and stabilize emulsions.
Tergitol np-4 has been used in oil spill dispersant formulations, where its surfactant properties help to break large oil slicks into smaller droplets, facilitating easier biodegradation by natural microbial processes in the environment.
In petroleum extraction, Tergitol np-4 is applied in enhanced oil recovery processes, where it reduces the interfacial tension between trapped oil and reservoir rocks, improving the mobility of the oil and increasing its yield.
Environmental cleanup efforts involving contaminated soils often employ Tergitol np-4 as a surfactant to mobilize and emulsify hydrophobic pollutants like petroleum hydrocarbons, allowing for their effective extraction and removal from the soil matrix.
Tergitol np-4 found in formulations for hard-surface cleaners, floor cleaners, and laundry detergents.
Helps remove tough stains and improve cleaning efficiency.
Tergitol np-4 added to concrete admixtures to improve wetting and dispersion properties.
Tergitol np-4 is used as a defoamer or emulsifier in construction applications.
Occasionally used in formulations like shampoos and body washes as a surfactant, although its use is declining due to environmental concerns.
Tergitol np-4 is used as an emulsifier in latex and rubber manufacturing processes.
Enhances the stability of polymer emulsions.
Part of formulations used to disperse oil slicks into smaller droplets, allowing natural degradation.
In the production of plastics and polymers, Tergitol np-4 is commonly employed as a processing aid and emulsifier, where it ensures uniform dispersion of various additives within the polymer matrix, ultimately contributing to enhanced material properties and improved processability.
During the manufacturing of synthetic rubber and elastomers, Tergitol np-4 plays a vital role as an emulsion stabilizer, ensuring that polymerization reactions proceed smoothly by maintaining uniform dispersion of reactants and preventing phase separation.
Tergitol np-4 is utilized in highly specialized cleaning solutions for the electronics and semiconductor industries, where it effectively removes stubborn organic residues, oils, and particulate contaminants from delicate circuit boards and microchip surfaces without causing damage.
The surfactant properties of Tergitol np-4 make it an ideal dispersant in the preparation of ceramic slurries and glass coatings, where it aids in achieving homogeneous mixtures and prevents particle agglomeration, leading to superior final product quality.
In industrial and commercial laundry applications, Tergitol np-4 is often included in detergent formulations for its ability to break down complex, oily, and greasy stains on fabrics, thereby enhancing the overall cleaning power of the detergent.
Tergitol np-4 is sometimes used in liquid dishwashing detergents due to its ability to emulsify fats and oils, ensuring that greasy residues are broken down and suspended in water for easy removal during the washing process.
As a key ingredient in carpet and upholstery cleaning formulations, Tergitol np-4 contributes by penetrating deep into fabric fibers to break apart and emulsify oily soils and stubborn stains, leaving surfaces clean and fresh.
Tergitol np-4 is included in many car cleaning products, where it works as a degreaser to dissolve and remove road tar, grease, and other oily contaminants from car exteriors, ensuring a thorough and streak-free clean.
Safety Profile:
Experimental reproductive effects.
When heated to decomposition it emits acridsmoke and irritating vapors.
Prolonged or repeated exposure to Tergitol np-4 may cause skin irritation, dryness, or redness. This is particularly a concern for individuals handling concentrated formulations.
Contact with the eyes can result in moderate to severe irritation, characterized by redness, watering, and discomfort.
In some cases, exposure may cause temporary damage to the ocular surface.
If aerosolized or inhaled in mist form, Tergitol np-4 can irritate the respiratory tract, causing coughing, shortness of breath, and throat irritation.
Chronic exposure to nonionic surfactants like Tergitol np-4 may lead to systemic effects, including potential damage to internal organs, although data on humans is limited.
