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TETRAETHYLENE GLYCOL DIMETHYL ETHER

 

Tetraethylene glycol dimethyl ether (TEGDME or tetraglyme) is a polar aprotic solvent with excellent chemical and thermal stability. Its high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions. TEGDME is also used in lithium-ion battery technology and combined with trifluoroethanol as a working pair for organic absorption heat pumps.


CAS NO:143-24-8
EC NO:205-594-7

IUPAC NAMES:
1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane
1-methoxy-2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethane
2,5,8,11,14-pentaoxapentadecane
Bis(2-(2-methoxyethoxy)ethyl) ether
bis(2-(2-methoxyethoxy)ethyl) ether
Tetraethylene Glycol Dimethyl Ether
Tetraglyme
Tetraglyme, Tetraethylene glycol dimethyl ether

SYNONYMS:
143-24-8 [RN]
1760005 [Beilstein]
2,5,8,11,14-Pentaoxapentadecan [German] [ACD/IUPAC Name]
2,5,8,11,14-Pentaoxapentadecane [ACD/Index Name] [ACD/IUPAC Name]
2,5,8,11,14-Pentaoxapentadécane [French] [ACD/IUPAC Name]
205-594-7 [EINECS]
78L136FLZ9
bis[2-(2-methoxyethoxy)ethyl] ether
dimethoxytetraethylene glycol
Dimethyltetraglycol
MFCD00008505 [MDL number]
SB0400000
Tetraethylene glycol dimethyl ether [Wiki]
tetraglyme
1-(2-methoxyethoxy)-2-[2-(2-methoxyethoxy)ethoxy]ethane
1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
1216628-15-7 [RN]
1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane
2-(2-methoxyethoxy)-1-[2-(2-methoxyethoxy)ethoxy]ethane
3,6,9,12,15-Pentaoxaheptadecane [ACD/Index Name] [ACD/IUPAC Name]
4-01-00-02404 (Beilstein Handbook Reference) [Beilstein]
bis(2-(2-methoxyethoxy)ethyl) ether
Bis[2-(2-methoxyethoxy) ethyl] ether
bis[2-(2-methoxyethoxy)ethyl]ether
CH3O[CH2CH2O]4CH3
Dimethoxytetraglycol
Dimethyl tetraglycol, Bis[2-(2-methoxyethoxy)ethyl]ether
E 181 (ether)
EINECS 205-594-7
Ether, bis(2-(2-methoxyethoxy)ethyl)
ether, bis[2-(2-methoxyethoxy)ethyl]
ether, bis-[2-(2-methoxyethoxy)ethyl]
Glyme 5
Glyme-5
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:46785
methyl-peg4-methyl
Methyltetraglyme200
P3G
P6G
PG6
TEGDME
tetra-ethylene glycol dimethyl ether
tetraethylene glycol dimethyl ether 98%
tetraethylene glycol dimethyl ether,98%
tetraethylene glycol dimethyl ether,99%
Tetraethyleneglycol dimethyl ether
Tetraethyleneglycoldimethylether
Tetraglyme-d6
UNII:78L136FLZ9
UNII-78L136FLZ9
WLN: 1O2O2O2O2O1


TETRAETHYLENE GLYCOL DIMETHYL ETHER


Article service life
Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Tetraethylene glycol dimethyl ether can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

Widespread uses by professional workers
Tetraethylene glycol dimethyl ether is used in the following products: inks and toners. This substance is used in the following areas: printing and recorded media reproduction. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Formulation or re-packing
Tetraethylene glycol dimethyl ether is used in the following products: welding & soldering products.
Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites
Tetraethylene glycol dimethyl ether is used in the following products: plant protection products and extraction agents.
Tetraethylene glycol dimethyl ether is used for the manufacture of: chemicals.
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).


General description
Tetraethylene glycol dimethyl ether or tetraglyme is an organic aprotic colourless solvent with film forming ability.

Application
Tetraglyme coating was applied on glucose sensors, such as Nafion by RF to render it “non fouling” and enhancing linking of bio mimetic molecules to the surface. Tetraglyme helps in selective adsorption of proteins while promoting cell adhesion.[1] Other general uses include as an electrolyte in lithium ion batteries.


Tetraethylene glycol dimethyl ether is an inert solvent especially well suited for API synthesis.

Benefits
inert solvent
high solubility for organometallic compounds
Tetraethylene glycol dimethyl ether is used in lithium-ion battery technology. It is associated with trifluoroethanol and used as a working pair for organic absorption heat pumps. It acts as a solvent for cleaning and degreasing due to its chemical and thermal stability. Moreover, it is a suitable solvent for high temperature reactions due to its high boiling point. Further, it is used in the selective adsorption of proteins during the promotion of cell adhesion.

Physical State :Liquid
Storage :Store at -20° C
Melting Point :-30° C
Boiling Point :275-276° C
Density :1.01 g/mL at 20° C


Chemical Properties
clear liquid
Uses
Tetraethylene glycol dimethyl ether is used as a solvent.
Uses
Solvent.

Tetraglyme
CAS: 143-24-8

Tetraglyme, also called tetraethylene glycol dimethyl ether, is a polar aprotic solvent with excellent thermal and chemical stability. Glymes, or glycol ethers, are a widely used family of saturated polyethers for increasing anion reactivity in a given system, thus affecting selectivity and reaction rates. Tetraglyme is one of the heavier ethylene oxide based glymes available commercially.

 

Tetraethylene glycol dimethyl ether  is an ideal solvent for separation processes and high temperature reactions. It is used as an additive for adsorption refrigeration and heat pumps (HVAC systems), as a reagent for lithium-ion batteries, and as a solvent for paints, cleaning products, inks, adhesives, and other coatings. It is a strong emulsifier, and can help prevent clogging of ink printer heads.

 
This compound is an environmentally-friendly alternative to many lab solvents, so it is also useful as an inert solvent for API synthesis in the pharmaceutical industry.

Bis(2-(2-methoxyethoxy)ethyl)ether, also named tetraethylene glycol dimethyl ether (TEGDME) or tetraglyme (used herein) is an organic, colourless aprotic solvent with high chemical and thermal stability. It is used in e.g. paints and coatings as well as in
separation processes and high temperature reactions.

Tetraglyme (tetraethylene glycol dimethyl ether) is an effective solvent for paints and coatings. It has high solvency and dispersants for pigments and dyes and can be used effectively in water-based coatings.

Based on data for tetraglyme and data read across from source substances monoglyme, diglyme and triglyme, further supported by assumed common metabolites 2-methoxyethanol and methoxyacetic acid.

Industry Uses    
Fuels and fuel additives
Lubricants and lubricant additives
Processing aids, not otherwise listed
Solvents (which become part of product formulation or mixture)

Consumer Uses    
Building/construction materials not covered elsewhere
Ink, toner, and colorant products
Lubricants and greases

Industry Processing Sectors
All other basic organic chemical manufacturing
All other chemical product and preparation manufacturing
Computer and electronic product manufacturing
Wholesale and retail trade

USES
*General term which includes clothes, shoes, backpacks/purses/luggage, jewelry, pet apparel, etc.; more specific terms (e.g. clothing, footwear, handwear) included as modifiers when known 
*Chemicals detected in substances or products (note that these chemicals may be absent from an 'ingredient list' for the product and thus unexpected, but have been detected in product testing studies)     
*Generic lubricants, lubricants for engines, brake fluids, oils, etc (does not include personal care lubricants)
*Related to electrical work (such as wiring of a building), electric current insulation materials, or other electrical components
*Related to computers or the manufacturing of computers    
*General equipment that does not fall into another category (communication equipment, lifting and handling equipment)
*Televisions and their manufacture    
*Manufacturing, export    Related to manufacturing for export (additional information unknown)
*Related to electrical work (such as wiring of a building), electric current insulation materials, or other electrical components    
*Related to metals - manufacturing of metals, casting of metals, production of metals, surface treatment of metals, etc    
*Radios (communication device)
*Paint removers, graffiti removers, or general solvents    
*Textiles used for clothing or furniture upholstery, processes related to textiles (e.g. softeners, anti wrinkle agents), or the processing/manufacturing of textiles

Tetraethylene Glycol Dimethyl Ether(tegdme or tetraglyme) is a polar aprotic solvent with excellent chemical and thermal stability.

Tetraethylene Glycol Dimethyl Ether  is high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions.

Tetraethylene Glycol Dimethyl Ether (TEGDME or tetraglyme) is a polar aprotic solvent with excellent chemical and thermal stability. Its high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions.

Tetraethylene Glycol Dimethyl Ether is also used in lithium-ion battery technology and combined with trifluoroethanol as a working pair for organic absorption heat pumps. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Tetraethylene Glycol Dimethyl Ether is listed as a Substance of Very High Concern under reach regulations. The glow discharge plasma deposition (GDPD) of Tetraethylene Glycol Dimethyl Ether is introduced as a novel method for obtaining surfaces that are resistant to protein adsorption and cellular attachment. Analysis of films by x‐ray photoelectron spectroscopy and several biological assays indicate the formation of a fouling resistant, PEO‐like surface on several substrata (e.g., glass, polytetrafluoroethylene, polyethylene). Adsorption of 125I‐radiolabelled proteins (fibrinogen, albumin and IgG) from buffer and plasma was very low (typically <20 ng/cm2) when compared to the untreated substrata, which exhibited much higher levels of protein adsorption.

Tetraethylene Glycol Dimethyl Ether ,
 Chemical formula: C10H22O5 ;
 Molar mass : 222.281 g•mol−1  ;
 Appearance: Colorless liquid ; 
Density: 1.009 g/mL[1] ; 
Melting point: 275–276 °C (527–529 °F; 548–549 K)[1] ; 
Solubility in water: Miscible ; 
Thermochemistry: Std enthalpy of ; formation (ΔfH⦵298):1134.6 kJ/mol  ; combustion (ΔcH⦵298): 6196.5 kJ/mol ;Flash point: 141 °C (286 °F; 414 K) ; Temperature: 200 °C (392 °F; 473 K) ; Lethal dose or concentration (LD, LC): LD50 (median dose);5,140 mg/kg (rat, oral) ;Categories: Glycol ethers.

Tetraethylene Glycol Dimethyl Ether is a chemical compound from the group of glycol ethers .

Tetraethylene Glycol Dimethyl Ether can be obtained by reacting ethanol with ethene oxide.

Tetraethylene Glycol Dimethyl Ether is a flammable, hardly inflammable, hygroscopic, little volatile, colorless liquid with a faint odor that is miscible with water. Tetraethylene Glycol Dimethyl Ether decomposes when heated.

Tetraethylene Glycol Dimethyl Ether is used as the solvent and coupling reagent.  Tetraethylene Glycol Dimethyl Ether is also used in brake and hydraulic fluids.

Tetraethylene Glycol Dimethyl Ether used as raw material for hydraulic brake fluids; Also Tetraethylene Glycol Dimethyl Ether  used in coatings, printing inks, specialty chemicals, cleaning products, cutting oils, deicing agents, anti sudsing agent for finely powdered materials, and food contact plastics (plasticizer); 95% used to make hydraulic brake fluid. Ethoxytriglycol is a low-volatility, high solvency

Tetraethylene Glycol Dimethyl Ether with excellent coupling properties. The versatility of ethoxytriglycol, Tetraethylene Glycol Dimethyl Ether is demonstrated by the variety of applications in which it may find use. Low volatility and excellent solvency make this

Tetraethylene Glycol Dimethyl Ether  a highly effective carrier solvent for textile dye processes. With superior surface tension characteristics, water solubility and solvency for oils, it has potential for use in household, institutional, industrial and special-purpose cleaners. The coupling ability of this product enhances performance and improves shelf stability of cleaning products.

Tetraethylene Glycol Dimethyl Ether, is a solvent used widely in commercial and industrial applications. Tetraethylene Glycol Dimethyl Ether is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.

Tetraethylene Glycol Dimethyl Ether is manufactured by the reaction of ethylene oxide with ethanol. As with other glycol ethers Tetraethylene Glycol Dimethyl Ether l has the useful property of being able to dissolve chemically diverse compounds.

Tetraethylene Glycol Dimethyl Ether  will dissolve oils, resins, grease, waxes, nitrocellulose, and lacquers. This is an ideal property as a multi-purpose cleaner, and, therefore, Tetraethylene Glycol Dimethyl Ether is used in products such as varnish removers and degreasing solutions. Tetraethylene Glycol Dimethyl Ether is a solvent with many commercial and industrial applications.

Tetraethylene Glycol Dimethyl Ether is found in multi-purpose cleaners such as varnish removers and degreasing solutions due to its ability to dissolve oils, resins, grease, waxes, nitrocellulose, and lacquer.

Tetraethylene Glycol Dimethyl Ether is used as a diluent for color additive mixtures in the food industry and in the pharmaceutical industry for the production of colored capsules.

Tetraethylene Glycol Dimethyl Ether is a colorless, neutral, weakly hygroscopic and slightly mobile liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents e.g. acetone, diethyl ether, methanol. Methyl triglycol enters into the typical alcohol reactions.

Tetraethylene Glycol Dimethyl Ether is used in brake fluid formulations and organic intermediates.  Tetraethylene Glycol Dimethyl Ethers and their derivatives tend to form peroxides in the presence of air or oxygen. Due to the hygroscopicity Tetraethylene Glycol Dimethyl Ether storage to prevent absorption of water has to be ensured.

Tetraethylene Glycol Dimethyl Ether is recommended to reduce moisture pickup by nitrogen blanketing of storage tanks. Storage tanks should be made from stainless steel. Alumina and other light metals are not suitable due to alcohol formation with methyl triglycol.

Tetraethylene Glycol Dimethyl Ether is used in lithium-ion battery technology. It is associated with trifluoroethanol and used as a working pair for organic absorption heat pumps. It acts as a solvent for cleaning and degreasing due to its chemical and thermal stability. Moreover, it is a suitable solvent for high temperature reactions due to its high boiling point. Further, it is used in the selective adsorption of proteins during the promotion of cell adhesion.

Tetraethylene Glycol Dimethyl Ether(tegdme or tetraglyme) is a polar aprotic solvent with excellent chemical and thermal stability.

Tetraethylene Glycol Dimethyl Ether is high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions.

Tetraethylene Glycol Dimethyl Ether is also used in lithium-ion battery technology and combined with trifluoroethanol as a working pair for organic absorption heat pumps. A colorless, odorless, viscous Tetraethylene Glycol Dimethyl Ether. Tetraethylene Glycol Dimethyl Ether has a sweet taste, but Tetraethylene Glycol Dimethyl Ether is poisonous if ingested.

Tetraethylene Glycol Dimethyl Ether  is the most important glycol commercially available and is manufactured on a large scale in the United States.

Tetraethylene Glycol Dimethyl Ether is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins. Tetraethylene Glycol Dimethyl Ether’s Formula : H(OCH2CH2)4OCH3 ; Formula Weight: 208.25; Boiling Point: 158-160°/5mm ; Density: 1.07 ; Refractive Index: 1.4450 ; Storage & Sensitivity Ambient temperatures.SolubilityWater solubility 999,999c

Tetraethylene Glycol Dimethyl Ether Applications are A very small fraction (less than 5%) may be used for other purposes, such as asphalt anti-stripping applications or as a chemical intermediate in other industrial processes.

Tetraethylene Glycol Dimethyl Ether Store away from oxidizing agents. Keep the container tightly sealed and store in cool, dry condition in well ventilated place.

Tetraethylene Glycol Dimethyl Ether Category is Glycol Ethers (E Series) ; Descriptionis Clear colorless liquid; [Acros Organics MSDS] .

Tetraethylene Glycol Dimethyl Ether Sources/Uses ;Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in the automobile industry in brake and hydraulic fluids, [IUCLID] Only available commercially in glycol ether mixtures; High boiling ethylene glycol ethers are mainly used in automotive hydraulic brake fluids. 

Tetraethylene Glycol Dimethyl Ether applied in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligands, polypeptide synthesis support, graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Tetraethylene Glycol Dimethyl Ether(tegdme or tetraglyme) is a polar aprotic solvent with excellent chemical and thermal stability. Tetraethylene Glycol Dimethyl Ether  is high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions.

Tetraethylene Glycol Dimethyl Ether is also used in lithium-ion battery technology and combined with trifluoroethanol as a working pair for organic absorption heat pumps. We investigated self-discharge characteristics of Li/S batteries using Tetraethylene Glycol Dimethyl Ether (TEGDME) electrolyte. The open circuit voltages (OCV) and discharge curves were measured as a function of storage time. The self-discharge of the Li/S battery depended on current collectors. Li/ Tetraethylene Glycol Dimethyl Ether /S batteries with stainless steel (SUS) current collector showed the highest self-discharge rate of 59% per month. The self-discharge rate of Li/ Tetraethylene Glycol Dimethyl Ether /S battery using Al current collector is 34% during initial 80 days, but only 36% after 360 days storage.


 

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