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TETRAHYDROXYPROPYL ETHYLENEDIAMINE THPE

Tetrahydroxypropyl ethylenediamine THPE is a chelating agent that binds with metal ions or metallic compounds, preventing them from adhering to a surface (such as skin, hair, or clothing) or causing contamination, such as in the case of trace amounts of iron.
Tetrahydroxypropyl ethylenediamine THPE's strong hydrogen bonding capability and water solubility make it particularly suitable for use in water-based systems and specialty formulations.
Tetrahydroxypropyl ethylenediamine THPE is widely used as a catalyst, crosslinking agent, and intermediate in polymer chemistry due to its multiple reactive hydroxyl and amine groups.

CAS Number: 102-60-3
EC Number: 203-041-4
Molecular Formula: C14H32N2O4
Molecular Weight: 292.41 g/mol

Synonyms: 102-60-3, Edetol, N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, Neutrol TE, Adeka Quadrol, Quadrol L, 1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol, Edetolum [Latin], Edetolum, 2-Propanol, 1,1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-, Edetol [USAN:INN], NSC 369219, TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE, HSDB 5349, EINECS 203-041-4, UNII-Q4R969U9FR, NSC-369219, Edetol (USAN), BRN 1781143, Neutrol TE (TN), CCRIS 8275, Ethylenediamine-N,N,N',N'-tetra-2-propanol, EDETOL [HSDB], EDETOL [USAN], EDETOL [INN], 2-Propanol, 1',1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-, EC 203-041-4, Edetolum (Latin), 4-04-00-01685 (Beilstein Handbook Reference), Tetra (2-hydroxypropyl) ethylenediamine, n,n,n',n'-tetrakis (2-hydroxypropyl) ethylenediamine, 1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL), RefChem:136287, Tetrakis(2hydroxypropyl)ethylenediamine, N,N,N',N'Tetra(2hydroxypropyl)ethylenediamine, 1,1',1',1'''(Ethylenedinitrilo)tetra2propanol, 1,1',1'',1'''(Ethylenedinitrilo)tetra2propanol, N,N,N',N'Tetrakis(2hydroxypropyl)ethylenediamine, 2Propanol, 1,1',1'',1'''(ethylenedinitrilo)tetra, 1,1',1'',1'''(Ethylenedinitrilo)tetrakis(2propanol), 2Propanol, 1,1',1',1'''(1,2ethanediyldinitrilo)tetrakis, 203-041-4, NSOXQYCFHDMMGV-UHFFFAOYSA-N, Quadrol, Entprol, 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol), Tetrahydroxypropyl ethylenediamine, MFCD00004534, 1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol, N,N,N',N'-Tetra(2-hydroxypropyl)ethylenediamine, 1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol, 2-Propanol, 1,1',1'',1'''-(ethylenedinitrilo)tetra-, 1,1',1'',1'''-(Ethylenedinitrilo)tetrakis(2-propanol), Q4R969U9FR, DTXSID9026689, NNN'N'-Tetrakis(2-Hydroxypropyl)ethylenediamine, N,N,N,N-Tetrakis(2-Hydroxypropyl)- Ethylenediamine, 1,1',1'',1'''-(Ethanediylnitrilo)tetrakis(2-propanol), NCGC00164339-02, DTXCID806689, N,N,N',N'-Tetrakis(2-Hydroxypropyl)ethylenediamine, 98%, CAS-102-60-3, n,n,n,n-tetrakis(2-hydroxypropyl)ethylenediamine, (Ethylenedinitrilo)tetra-2-propanol, N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine;EDTP, Quadrol(R), ENTPROL [MI], SCHEMBL48412, MLS004773924, 1,1',1',1'''-(Ethylenedinitrilo)tetra-2-propanol, orb1306107, CHEMBL1573178, CHEBI:193592, HMS3264C08, Pharmakon1600-01301023, 2-Propanol, 1,1',1',1'''-(1,2-ethanediyldinitrilo)tetrakis-, HY-B2149, Tox21_112102, Tox21_201973, Tox21_300552, NSC369219, NSC760394, tetra(2-hydroxypropyl)ethylenediamine, 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))-tetrakis(propan-2-ol), 1-({2-[bis(2-hydroxypropyl)amino]ethyl}(2-hydroxypropyl)amino)propan-2-ol, AKOS015892820, Tox21_112102_1, CCG-230630, NSC-760394, SB82446, NCGC00164339-01, NCGC00164339-03, NCGC00164339-04, NCGC00164339-05, NCGC00254289-01, NCGC00259522-01, BS-23689, DA-52809, SMR001600027, SY011184, CS-0020301, ethane, 1,2-bis(di-2-hydroxypropylamino)-, NS00009765, ST50308044, T0781, D03948, F71260, Tetrakis-[N-(2-hydroxy-propyl)]-ethylenediamine, BRD-A78588743-001-03-4, N,N,N',N'-tetrakis-(2-hydroxypropyl)ethylenediamine, N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine;EDTP, Q26841009, 4,7-Diazadecane-2,9-diol, 4,7-bis(2-hydroxypropyl)-, N,N,N',N'-Tetrakis(2-hydroxyprop-1-yl)ethane-1,2-diamine, 1,1',1'',1'''-(Ethane-1,2-diyldinitrilo)tetra(propan-2-ol), 1,1a(2),1a(2)a(2),1a(2)a(2)a(2)-(Ethylenedinitrilo)tetrakis(2-propanol), N,N,N inverted exclamation mark ,N inverted exclamation mark -Tetrakis(2-Hydroxypropyl)ethylenediamine, N,N,N inverted exclamation marka,N inverted exclamation marka-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP

Tetrahydroxypropyl ethylenediamine THPE is a reaction product of ethylenediamine with 4 moles of propylene oxide.
Tetrahydroxypropyl ethylenediamine THPE is formulated with the feature high alcohol compatibility to stimulate a pleasant, nonsticky sensation on the skin.
Tetrahydroxypropyl ethylenediamine THPE is used for the manufacture of soap and stearate cremes.

Tetrahydroxypropyl ethylenediamine THPE is a multifunctional compound containing both amine and polyol functionalities, formed by the reaction of ethylenediamine with propylene oxide.
Tetrahydroxypropyl ethylenediamine THPE's structure includes four hydroxypropyl groups attached to an ethylenediamine core, providing high reactivity and excellent compatibility in aqueous systems.

Tetrahydroxypropyl ethylenediamine THPE is widely used as a catalyst, crosslinking agent, and intermediate in polymer chemistry due to its multiple reactive hydroxyl and amine groups.
Tetrahydroxypropyl ethylenediamine THPE plays an important role in polyurethane systems, epoxy formulations, and coatings where enhanced reactivity and improved network formation are required.

Tetrahydroxypropyl ethylenediamine THPE's strong hydrogen bonding capability and water solubility make it particularly suitable for use in water-based systems and specialty formulations.
Tetrahydroxypropyl ethylenediamine THPE is a synthetic compound.

Tetrahydroxypropyl ethylenediamine THPE is formed by reacting ethylenediamine with propylene oxide.
Tetrahydroxypropyl ethylenediamine THPE is used as an ingredient in cosmetic and personal care products.

Uses of Tetrahydroxypropyl Ethylenediamine THPE:
Tetrahydroxypropyl ethylenediamine THPE is widely used in polymer and specialty chemical industries due to its multifunctional amine and polyol structure.
Tetrahydroxypropyl ethylenediamine THPE plays a key role as a catalyst and crosslinking agent in polyurethane systems, where it enhances curing efficiency and contributes to the formation of strong, durable polymer networks.

In epoxy resin formulations, Tetrahydroxypropyl ethylenediamine THPE is used as a curing agent or modifier to improve mechanical properties and overall performance.
Tetrahydroxypropyl ethylenediamine THPE is also incorporated into coatings, adhesives, and sealants to support better adhesion, film formation, and stability.
Additionally, Tetrahydroxypropyl ethylenediamine THPE serves as an important intermediate in the synthesis of specialty chemicals and is particularly valuable in water-based formulations due to its excellent solubility and compatibility.

Tetrahydroxypropyl ethylenediamine THPE is used as a catalyst in manufacturing urethane foams, epoxy resin curing agent, complexing agent, humectant, plasticizer, chelate, surfactant solubilizer, viscosity modifier, and intermediate.
Tetrahydroxypropyl ethylenediamine THPE is also used as an anti-bloating agent for cattle.
Tetrahydroxypropyl ethylenediamine THPE is used in piezoelectric crystal detectors

Epidermal Changes:
Tetrahydroxypropyl ethylenediamine THPE is used to induce changes in superficial epidermal keratinocytes.
Tetrahydroxypropyl ethylenediamine THPE leads to immediate and long-term clinical improvement in skin appearance and can therefore be considered a new anti-aging cosmetic active ingredient.

Chelating Agent:
Tetrahydroxypropyl ethylenediamine THPE functions as a chelating agent, binding to the metallic ions present in the product.
Tetrahydroxypropyl ethylenediamine THPE stabilizes the product by preventing these metallic ions from reacting with other compounds in the cosmetic product.

Stability:
They give stability to Tetrahydroxypropyl ethylenediamine THPE and enhance its efficacy too.

Cosmetic Applications:
Tetrahydroxypropyl ethylenediamine THPE is used in formulations of creams, lotions, gels, make-up, sunscreens, and other skin and hair care products.

Chemical Roles:
In a chemical way, Tetrahydroxypropyl ethylenediamine THPE has several roles, such as being used as a solvent, cleansing agent, emulsifying agent, dispersing agent, corrosion inhibitor, lubricant, antistatic agent, and as an intermediate in organic synthesis.

Industry Uses:
Plating agents and surface treating agents
Paint additives and coating additives not described by other categories
Cleaning agent
Chelating agent
Flame retardant
Plasticizers
Other (specify)

Consumer Uses:
Other (specify)
Plasticizers
Sealant (barrier)
Paint additives and coating additives not described by other categories

Advantages of Tetrahydroxypropyl Ethylenediamine THPE:

Multifunctional Structure:
Tetrahydroxypropyl ethylenediamine THPE contains both amine and multiple hydroxyl groups, enabling diverse reactivity in formulations.

High Reactivity:
Tetrahydroxypropyl ethylenediamine THPE participates efficiently in curing and crosslinking reactions, improving process performance and product quality.

Excellent Water Solubility:
Tetrahydroxypropyl ethylenediamine THPE dissolves easily in water, making it ideal for aqueous and environmentally friendly systems.

Enhanced Crosslinking Efficiency:
Tetrahydroxypropyl ethylenediamine THPE contributes to strong and stable polymer networks, improving mechanical strength and durability.

Improved Adhesion:
Tetrahydroxypropyl ethylenediamine THPE enhances bonding performance in coatings, adhesives, and sealants.

Versatile Application Range:
Tetrahydroxypropyl ethylenediamine THPE is suitable for use in polyurethanes, epoxies, coatings, textiles, and specialty chemicals.

Process Flexibility:
Tetrahydroxypropyl ethylenediamine THPE performs well under various processing conditions, supporting efficient formulation design.

Compatibility:
Tetrahydroxypropyl ethylenediamine THPE is compatible with a wide range of resins, additives, and formulation components.

Stability and Reactivity of Tetrahydroxypropyl Ethylenediamine THPE:

Chemical stability:
Stable under normal conditions.

Reactivity:
Reactive due to amine groups.
Reactive due to hydroxyl groups.

Conditions to avoid:
Excessive heat.
Strong oxidizing environments.

Incompatible materials:
Strong oxidizing agents.
Strong acids.

Hazardous decomposition products:
Carbon monoxide (CO) may form.
Carbon dioxide (CO₂) may be generated.
Nitrogen oxides (NOₓ) may be released.

Handling and Storage of Tetrahydroxypropyl Ethylenediamine THPE:

Handling:
Use with adequate ventilation.
Avoid unnecessary contact.

Storage:
Store in tightly closed containers.
Keep in a cool, dry place.

First Aid Measures of Tetrahydroxypropyl Ethylenediamine THPE:

Inhalation:
Move to fresh air.

Skin contact:
Wash with water.

Eye contact:
Rinse with water.

Ingestion:
Rinse mouth.

Firefighting Measures of Tetrahydroxypropyl Ethylenediamine THPE:

Suitable extinguishing media:
Foam.
Carbon dioxide (CO₂).
Dry chemical.

Hazards:
Irritating fumes may be released.

Protection:
Use self-contained breathing apparatus.

Accidental Release Measures of Tetrahydroxypropyl Ethylenediamine THPE:

Precautions:
Avoid contact.
Ensure adequate ventilation.

Cleanup:
Absorb with inert material.
Collect for disposal.

Exposure Controls / Personal Protection of Tetrahydroxypropyl Ethylenediamine THPE:

Ventilation:
Ensure adequate ventilation.

Hand protection:
Use protective gloves.

Eye protection:
Use safety goggles.

Skin protection:
Wear protective clothing.

Hygiene:
Wash after use.

Identifiers of Tetrahydroxypropyl Ethylenediamine THPE:
CAS Number: 102-60-3
EC Number: 203-041-4
Molecular Formula: C₁₄H₃₂N₂O₄
Molecular Weight: 292.41 g/mol
Chemical Class: Polyfunctional amine / polyol

CAS Number: 102-60-3
ECHA EINECS - REACH Pre-Reg: 203-041-4
FDA UNII: Q4R969U9FR
Nikkaji Web: J5.514J
Beilstein Number: 1781143
MDL: MFCD00004534
XlogP3-AA: -0.70 (est)
Molecular Weight: 292.41984000
Formula: C14 H32 N2 O4

CAS Number: 102-60-3
Chem/IUPAC Name: 1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol
EINECS/ELINCS No: 203-041-4
COSING REF No: 38562

Properties of Tetrahydroxypropyl Ethylenediamine THPE:
Appearance: Colorless to pale yellow viscous liquid
Odor: Mild, amine-like
Density (20–25°C): ~1.05–1.10 g/cm³
Boiling Point: High (decomposes before boiling)
Flash Point: ~150–170°C
Solubility: Fully miscible with water
pH: Basic
Viscosity: High
Refractive Index: ~1.47–1.49

Molecular Weight: 292.41 g/mol
XLogP3-AA: -0.7
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 11
Exact Mass: 292.23620751 Da
Monoisotopic Mass: 292.23620751 Da
Topological Polar Surface Area: 87.4 Å²
Heavy Atom Count: 20
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 4
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes