TETRAISOPROPYL TITANATE

TETRAISOPROPYL TITANATE = Titanium tetraisopropanolate = Titanium isopropoxide

CAS Number : 546-68-9 
EC Number  : 208-909-6
ECHA InfoCard : 100.008.100 
PubChem CID   : 11026
ChemSpider    : 21106214
Chemical formula : C12H28O4Ti
Molar mass     : 284.219 g·mol−1
Density          : 0.96 g/cm3
Melting point     : 17 °C

IUPAC name : Titanium isopropoxide
Other names : 
-Tetraisopropyl titanate
-Titanium(IV) i-propoxide
-Titanium tetraisopropoxide
-Tetraisopropyl orthotitanate

Tetraisopropyl titanate, also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4. 
This alkoxide of titanium(IV) is used in organic synthesis and materials science. 
Tetraisopropyl titanate is a diamagnetic tetrahedral molecule. 
Tetraisopropyl titanate is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.

The structures of the Tetraisopropyl titanates are often complex. 
Crystalline titanium methoxide is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less. 
Tetraisopropyl titanate is mainly a monomer in nonpolar solvents.

Preparation of TETRAISOPROPYL TITANATE
Tetraisopropyl titanate is prepared by treating titanium tetrachloride with isopropanol. Hydrogen chloride is formed as a coproduct:
TiCl4 + 4 (CH3)2CHOH → Ti{OCH(CH3)2}4 + 4 HCl

Properties of TETRAISOPROPYL TITANATE
Tetraisopropyl titanate reacts with water to deposit titanium dioxide:
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH

This reaction is employed in the sol-gel synthesis of TiO2-based materials in the form of powders or thin films. 
Typically water is added in excess to a solution of the alkoxide in an alcohol. 
The composition, crystallinity and morphology of the inorganic product are determined by the presence of additives (e.g. acetic acid), the amount of water (hydrolysis ratio), and reaction conditions.
The compound is also used as a catalyst in the preparation of certain cyclopropanes in the Kulinkovich reaction. 
Prochiral thioethers are oxidized enantioselectively using a catalyst derived from Ti(O-i-Pr)4.

Tetraisopropyl titanate can be used as a precursor for ambient conditions vapour phase deposition such as infiltration into polymer thin films.
Tetraisopropyl titanate is a widely used item of commerce and has acquired many names in addition to those listed in the table. 
A sampling of the names include: titanium(IV) i-propoxide, isopropyl titanate, tetraisopropyl titanate, tetraisopropyl orthotitanate, titanium tetraisopropylate, orthotitanic acid tetraisopropyl ester, Isopropyl titanate(IV), titanic acid tetraisopropyl ester, isopropyltitanate, titanium(IV) isopropoxide, titanium tetraisopropoxide, iso-propyl titanate, titanium tetraisopropanolate, tetraisopropoxytitanium(IV), tetraisopropanolatotitanium, tetrakis(isopropoxy) titanium, tetrakis(isopropanolato) titanium, titanic acid isopropyl ester, titanic acid tetraisopropyl ester, titanium isopropoxide, titanium isopropylate, tetrakis(1-methylethoxy)titanium.

Tetraisopropyl titanate appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol. 
About the same density as water. 
Vapors heavier than air.
Titanium(IV) isopropoxide is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.

Use and Manufacturing of TETRAISOPROPYL TITANATE
Used for heat-resistant surface coatings in paints, lacquers, and plastics; for hardening and cross-linking of epoxy, silicon, urea, melamine, and terephthalate resins and adhesives; and for adhesion of paints, rubber, and plastics to metals; Also used in catalysts, glass surface treatments, flue gas sorbents, controlled-release pesticides, and dental compositions (to bond to enamel); [HSDB] Used to make nano-sized titanium dioxide;

Used for the hardening and cross-linking of epoxy, silicon, urea, melamine, and terephthalate resins; in the manufacture of noncorrodible, high temperature lacquers; in the sol-gel process; as water repellents and adhesive agents (especially with foils); to improve glass surfaces; as a catalyst in olefin polymerization, and for condensation and esterification.

Industry Uses of TETRAISOPROPYL TITANATE
-Catalyst
-Chemical substance used to manufacture glass.
-Ion exchange agents
-Lubricants and lubricant additives
-Paint additives and coating additives not described by other categories
-Plasticizers
-Process regulators
-catalyst

Consumer Uses of TETRAISOPROPYL TITANATE
-Catalyst
-Glass products

Household Products of TETRAISOPROPYL TITANATE
Household & Commercial/Institutional Products
Information on 1 consumer products that contain Tetraisopropyl titanate in the following categories is provided:
-Auto Products

Methods of Manufacturing of TETRAISOPROPYL TITANATE
Reaction of titanium tetrachloride with isopropanol.

General Manufacturing Information    
Industry Processing Sectors
-All other basic inorganic chemical manufacturing
-All other basic organic chemical manufacturing
-All other chemical product and preparation manufacturing
-All other petroleum and coal products manufacturing
-Construction
-Nonmetallic mineral product manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other nonmetallic mineral product manufacturing.
-Paint and coating manufacturing
-Plastic material and resin manufacturing
-Plastics product manufacturing

​Tetra Isopropyl Titanate (TIPT) belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications. 
​Tetra Isopropyl Titanate (TIPT) is a colorless, slighty yellowish liquid that is very sensitive to moisture.

Applications of TETRAISOPROPYL TITANATE
-Catalyst to produce plasticizers, polyesters and methacrylic esters
-Adhesion promoter
-Cross-linking for polymers
-Coatings
-Surface modification (metal, glass)

Tetraisopropyl titanate is extremely moisture sensitive and decomposes when exposed to water. 
Tetraisopropyl titanate is a metal catalyst used for the production of polyolefins and polycarbonate. 
Tetraisopropyl titanate improves yield of olefin polymerization, esterification, condensation, and addition reactions while also eliminating unwanted by-products.
Tetraisopropyl titanate is useful as a replacement for tin, organostannanes, and sulfuric acid in esterification reactions when a reduction of toxicity is desired. 
In fact, Tetraisopropyl titanate is more efficient than sulfuric acid in esterification reactions as well. 

Tetraisopropyl titanate can be added to solvent borne paints to cross link hydroxyl and carboxyl functional polymers as well. 
In addition, Tetraisopropyl titanate can be used to coat metal and glass surfaces with a thin polymeric film of titanium dioxide. 
This can promote adhesion, improve surface hardness, increase light reflection, and add coloring effects.

Tetraisopropyl titanate - Use
The catalyst for the esterification reaction is used for the transesterification reaction of esters such as acrylic acid and the polymerization of epoxy resin, phenolic plastic, silicone resin, polybutadiene, PP and PE. 
Tetraisopropyl titanate can also be used as raw materials for the pharmaceutical industry and the preparation of metal and rubber, metal and plastic adhesives. 
Tetraisopropyl titanate can also be used as surface modifier, adhesion promoter and paraffin and oil additives.

Tetraisopropyl titanate is a titanium-based coordination compound, commonly used in the asymmetric Sharpless epoxidation reaction of allylic alcohols. 
Tetraisopropyl titanate is also used as a catalyst in Kulinkovich reaction for the synthesis of cyclopropanes.
Commonly used as a precursor for the preparation of Titania (TiO2)
Novel metal oxide/phosphonate hybrids were formed from titanium(IV) isopropoxide in a two-step sol-gel process. 
Starting material for barium-strontium-titanate thin films. 
Used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes. 
Applied in the formation of a heterosupermolecule consisting of a TiO2 nanocrystallite-viologen electron acceptor complex whose light-induced electron transfer has been demonstrated.

Tetraisopropyl titanate is a type of very lively primary alcohol titanium oxide; it hydrolyzes when contacted with moisture in air. 
Tetraisopropyl titanate is mainly used as catalyst in esterification reaction or transesterification,also being used as catalyst of polyolefin. 
Tetraisopropyl titanate can be used to improve the adherence and crosslinking of resin having alcohol group or carboxyl group, used in heat resistant and corrosion resistant coating. 
Tetraisopropyl titanate also can be used in the manufacture of glass and glass fiber. TIPT can only be used in oil system.

Applications:
Coating: Glass, metals, fillers and pigments can be treated with TIPT to give increased surface hardness; adhesion promotion; heat, chemical and scratch resistance; coloring effects; light reflection; iridescence; and corrosion resistance
Paint additive: Tetraisopropyl titanate can be used as an additive in paints to cross-link -OH functional polymers or binders; to promote adhesion; or to act as a binder itself.
TiO2 pigments and films: Micro- or nano-scale TiO2 pigments can be formed from TIPT. Tetraisopropyl titanate can also be used to create a polymeric TiO2 film on surfaces via pyrolytic or hydrolytic processes.

Tetraisopropyl titanate is a chemical compound with the formula Ti{OCH(CH3)2}4. 
This alkoxide of titanium(IV) is used in organic synthesis and materials science.
The structures of the Tetraisopropyl titanate are often complex. 
Crystalline titanium methoxide is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such isopropanol aggregate less. 
Tetraisopropyl titanate is mainly a monomer in nonpolar solvents.
Tetraisopropyl titanate is a diamagnetic tetrahedral molecule.

Tetraisopropyl Titanate 546-68-9 is colorless to light-yellow liquid. 
Tetraisopropyl Titanate is also known as Tetraisopropyl orthotitanate and Titanium tetraisopropoxide. 
Storage: Keep container tightly closed. 
Keep container in a cool, well-ventilated area.
Waste Disposal: 
Waste must be disposed of in accordance with federal, state and local environmental control regulations.

Tetra-Isopropyl Titanate is an intermediate derived from titanium. 
This product appears as a light yellow, transparent liquid. 
Tetra-Isopropyl Titanate can be used as a catalyst additive in coating primers or added to that formulation as an adhesion promoter.

Tetraisopropyl titanate is used as a catalyst for esterification reaction and transesterification reaction of esters such as acrylic acid. 
Used as Ziegler Natta catalyst in the polymerization of epoxy resin, phenolic plastic, silicone resin, polybutadiene, PP, PE, etc., it has high stereoselectivity and benefits. 
Used in paints to cross-link a variety of polymers or resins, improve the anti-corrosion ability of the coating, etc., and also promote the adhesion of the coating to the surface. 
Tetraisopropyl titanate can also be directly used as material surface modifier, adhesion promoter, primer, and the adhesion of topcoat to materials. 
Tetraisopropyl titanate decomposes at high temperature (300-650℃) to form a hard and smooth titanium dioxide film layer.

TETRAISOPROPYL TITANATE is a metal alkoxide, a strong . 
About the same density as water. 
Starting material for barium-strontium- titanate thin films.
Tetraisopropyl titanate used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes. 
Applied in the formation of a heterosupermolecule consisting of a TiOnanocrystallite-viologen electron acceptor complex whose light-induced electron transfer .

FEATURES AND BENEFITS OF TETRAISOPROPYL TITANATE:
-Highly reactive and moisture sensitive
-Lewis acid catalyst
-Ziegler-Natta catalyst
-Low toxicity
-Cross linking agent for hydroxyl and carboxyl functional polymers
-Forms polymeric TiO2 films
-Promotes adhesion
-Increase light reflection of glass

Tetraisopropyl titanate appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol. 
Tetraisopropyl titanate about the same density as water. 
Tetraisopropyl titanate is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.
Tetraisopropyl titanate is a synthetic ingredient used as a surface treatment for cosmetic pigments in products such as mascara because of its ability to help form a uniform coating which suspends and helps disperse pigments.

Tetraisopropyl titanate is a synthetic compound derived from fatty acids. 
Tetraisopropyl titanate is most often used in beauty products and cosmetics in relation to coloring and pigmentation because it is very reactive to almost all pigments and consistently forms a uniform coating. 
Tetraisopropyl titanate commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4. 

Tetraisopropyl titanate alkoxide of titanium(IV) is used in organic synthesis and materials science. 
Tetraisopropyl titanate is a diamagnetic tetrahedral molecule. 
Tetraisopropyl titanate is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.
The structures of the Tetraisopropyl titanates are often complex. 
Crystalline Tetraisopropyl titanate is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less. 
Tetraisopropyl titanate is mainly a monomer in nonpolar solvents.

First-aid measures of TETRAISOPROPYL TITANATE

Eye Contact 
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. 
If eye irritation persists: Get medical advice/attention.

Skin Contact 
Wash off immediately with plenty of water for at least 15 minutes. 
Immediate medical attention is required.

Inhalation 
Remove to fresh air. 
Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped withaone-wayvalve or other proper respiratory medical device. 
Immediate medical attention is required.

Ingestion 
Do NOT induce vomiting. 
Call a physician or poison control center immediately.

Substance identity

EC / List no.: 208-909-6
CAS no.: 546-68-9
Mol. formula: C3H8O.1/4Ti

Hazard classification & labelling of TETRAISOPROPYL TITANATE
Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation, is a flammable liquid and vapour, is a flammable solid and may cause drowsiness or dizziness.

About TETRAISOPROPYL TITANATE
TETRAISOPROPYL TITANATE is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
TETRAISOPROPYL TITANATE is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of TETRAISOPROPYL TITANATE
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. 
ECHA has no public registered data on the routes by which TETRAISOPROPYL TITANATE is most likely to be released to the environment.

Article service life of TETRAISOPROPYL TITANATE
ECHA has no public registered data on the routes by which TETRAISOPROPYL TITANATE is most likely to be released to the environment. 
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers of TETRAISOPROPYL TITANATE
TETRAISOPROPYL TITANATE is used in the following products: pH regulators and water treatment products, laboratory chemicals and water treatment chemicals.
TETRAISOPROPYL TITANATE is used in the following areas: health services and scientific research and development.
TETRAISOPROPYL TITANATE is used for the manufacture of: chemicals.

Release to the environment of TETRAISOPROPYL TITANATE can occur from industrial use: manufacturing of the substance.
Other release to the environment of TETRAISOPROPYL TITANATE  is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Formulation or re-packing of TETRAISOPROPYL TITANATE
TETRAISOPROPYL TITANATE is used in the following products: adhesives and sealants, coating products and lubricants and greases.
Release to the environment of TETRAISOPROPYL TITANATE can occur from industrial use: formulation of mixtures.

Uses at industrial sites of TETRAISOPROPYL TITANATE
TETRAISOPROPYL TITANATE is used in the following products: polymers, fuels, coating products, lubricants and greases, pH regulators and water treatment products and laboratory chemicals.
TETRAISOPROPYL TITANATE has an industrial use resulting in manufacture of another substance (use of intermediates).
TETRAISOPROPYL TITANATE is used in the following areas: health services and scientific research and development.
TETRAISOPROPYL TITANATE is used for the manufacture of: chemicals and plastic products.

Release to the environment of TETRAISOPROPYL TITANATE can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in processing aids at industrial sites.

Manufacture of TETRAISOPROPYL TITANATE
Release to the environment of TETRAISOPROPYL TITANATE can occur from industrial use: manufacturing of the substance.

Synonyms:
Titanium tetraisopropanolate
Titanium(IV) isopropoxide
546-68-9
Titanium isopropoxide
Tetraisopropyl orthotitanate
Titanium isopropylate
Titanium tetraisopropylate
Ti Isopropylate
Titanium tetraisopropoxide
Tetraisopropoxytitanium(IV)
Tilcom TIPT
Tetraisopropanolatotitanium
TETRAISOPROPYL TITANATE
A 1 (titanate)
Orgatix TA 10
Tetraisopropoxytitanium
Tetrakis(isopropoxy)titanium
Isopropyl titanate(IV)
Isopropyl orthotitanate
Tyzor TPT
Isopropyl Titanate
UNII-76NX7K235Y
TTIP
Tetraisopropoxide titanium
Titanium tetra-n-propoxide
Titanium(4+) isopropoxide
Titanic acid isopropyl ester
Titanium(IV) i-propoxide
Titanium tetrakis(isopropoxide)
titanium(IV)tetraisopropoxide
2-Propanol, titanium(4+) salt
titanium(IV) propan-2-olate
propan-2-olate;titanium(4+)
Titanium(IV) Tetraisopropoxide
Isopropyl alcohol titanium(4+) salt
Titanium, tetrakis(1-methylethoxy)-
76NX7K235Y
Isopropyl titanate(IV) ((C3H7O)4Ti)
2-Propanol, titanium(4+) salt (4:1)
Isopropyl alcohol, titanium(4+) salt
titanium tetra(isopropoxide)
Titanium isopropylate (VAN)
TITANIUM (IV) ISOPROPOXIDE
HSDB 848
Tetraksi(isopropanolato)titanium
MFCD00008871
Isopropyl alcohol, titanium salt
Titanic acid tetraisopropyl ester
EINECS 208-909-6
Titanium isopropoxide (Ti(OCH7)4)
NSC 60576
Titanic(IV) acid, tetraisopropyl ester
TIPT
Ti(OiPr)4
tetraisopropoxy titanium
tetraisopropoxy-titanium
titaniumtetraisopropoxide
titaniumtetraisopropylate
titanium(IV)isopropoxide
tetra-isopropoxy titanium
titanium (IV)isopropoxide
tetra-iso-propoxy titanium
titanium tetra-isopropoxide
titanium-tetra-isopropoxide
EC 208-909-6
titanium (4+) isopropoxide
tetraisopropoxytitanium (IV)
C12H28O4Ti
titanium tetra (isopropoxide)
titanium (IV)tetraisopropoxide
titanium (IV) tetraisopropoxide
tetrakis(propan-2-yloxy)titanium
CHEBI:139496
AKOS015892702
T0133
W6889
Q2031021
Titanium tetraisopropanolate
titanium tetraisopropanolate
2-Propanol, titanium(4+) salt (4:1)
2-Propanol - titanium (4:1)
2-Propanol, titanium(4+) salt
2-propanol, titanium(4+) salt
2-Propanol, titanium(4+) salt (4:1)
isopropyltitanate
propan-2-ol; titanium
propan-2-olate; titanium(4+)
propan-2-olate;titanium(4+)
Tetraisopropyl Orthotitanate
Tetraisopropyl orthotitanate
Tetraisopropyl orthotitanate, Titanium(IV) isopropoxide
TETRAISOPROPYL TITANATE
Tetraisopropyl titanate
TIPT
Titanium isopropoxide
titanium isopropoxide
Titanium tetraisopropanolate
titanium tetraisopropanolate
titanium tetraisopropanolate
titanium tetraisopropanolato
Titanium tetrakis(propan-2-olato)
titanium(4+) ion tetrakis(propan-2-olate)
titanium(4+) tetrakis(propan-2-olate)
Titanium(IV) isopropoxide
TITANIUM(IV) ISOPROPOXIDE;
Titanium(IV) propan-2-olate
Titantetraisopropanolat
Tyzor TPT
TETRAISOPROPYL TITANATE, 51% IN HEPTANE
Tytan TIPT
TYZOR® TPT
Tyzor®TPT
VERTEC AC213
VERTEC AC470
VERTEC AC715
VERTEC TIPT
VERTEC VEXP0589
VERTEC XL110
VERTEC XL206
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