Quick Search
CAS NUMBER: 80-70-6
EC NUMBER: 201-302-7
MOLECULAR FORMULA: C5H13N3
MOLECULAR WEIGHT: 115.18
Tetramethylguanidine is an organic compound with the formula HNC(N(CH3)2)2.
Tetramethylguanidine is a strong base, as judged by the high pKa of it conjugate acid.
Tetramethylguanidine was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide.
Tetramethylguanidine is an organic superbase which has recently found use as a primary functional group in alkaline anion exchange membranes (AAEM).
Tetramethylguanidine, an organic compound, is used as a non-nucleophilic base for alkylations and in the production of polyurethane as a base-catalyst.
USAGE OF TETRAMETHYLGUANIDINE:
Tetramethylguanidine are widely used in the synthesis of pharmaceutical and chemical raw materials.
Base employed in the preparation of alkyl nitriles from alkyl halides and 3'-alkylthymidines from 3'-nitrothymidines.
Tetramethylguanidine promotes the pentavalent bismuth oxidation of primary and secondary alchohols to aldehydes and ketones.
Tetramethylguanidine is mainly used as a strong, non-nucleophilic base for alkylations, often as a substitute for the more expensive DBU and DBN.
Since Tetramethylguanidine is highly water-soluble, it is easily removed from mixtures in organic solvents.
Tetramethylguanidine is also used as a base-catalyst in the production of polyurethane.
Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber.
Tetramethylguanidine is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries.
Tetramethylguanidine is essential for the preparation of alkyl nitriles from alkyl halides and 3'-alkylthymidines from 3'-nitrothymidines.
Tetramethylguanidine serves as an efficient and selective catalyst for the benzoylation of alcohols.
Tetramethylguanidine replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.
Tetaramethylguanidine is used as a strong, non-nucleophilic base for alkylations in organic synthesis.
Tetramethylguanidine is an efficient and selective catalyst for the benzoylation of alcohols.
Tetramethylguanidine (TMG) is used as polyurethane foam catalyst, as accelerator for the syntheses of polysulfured rubber, as a strong base in the photochemical (e.g. couplers) and in the pharmaceutical (e.g. steroids) industries.
Tetaramethylguanidine is used as a strong, non-nucleophilic base for alkylations in organic synthesis.
Tetramethylguanidine is an efficient and selective catalyst for the benzoylation of alcohols.
PROPERTIES OF TETRAMETHYLGUANIDINE:
-Quality Level: 200
-vapor pressure: 0.2 mmHg ( 20 °C)
-assay: 99%
-refractive inde: n20/D 1.469 (lit.)
-Boiling point: 52-54 °C/11 mmHg (lit.)
-density: 0.918 g/mL at 25 °C (lit.)
-SMILES string: CN(C)C(=N)N(C)C
-InChI: 1S/C5H13N3/c1-7(2)5(6)8(3)4/h6H,1-4H3
-InChI key: KYVBNYUBXIEUFW-UHFFFAOYSA-N
PHYSICAL AND CHEMICAL PROPERTIES OF TETRAMETHYLGUANIDINE:
-Boiling point: 162 °C (1013 hPa)
-Density: 0.92 g/cm3 (20 °C)
-Explosion limit: 1.0 - 7.5 %(V)
-Flash point: 50 °C
-Ignition temperature: 222 °C
-Melting Point: <-80 °C
-pH value: 12.7 (10 g/l, H²O, 25 °C)
-Vapor pressure: 2.9 hPa (20 °C)
-Refractive Index: 1.4659 (20 °C, 589 nm)
CHEMICAL PROPERTIES OF TETRAMETHYLGUANIDINE:
-Formula: C5H13N3
-Formula Weight: 115.18
-Melting point: <-30°
-Boiling Point: 162°
-Flash Point: 60°(140°F)
-Density: 0.918
CHARACTERISTICS OF TETRAMETHYLGUANIDINE:
-Boiling Point: 160-162ºC
-Stability: Stable. Combustible. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Air-sensitive.
-Storage Condition: 2-8ºC
-Appearance & Physical State: Clear liquid
-Water Solubility: miscible
-Flash Point: 60ºC
-Refractive Index: 1.467-1.469
-Density: 0.918
-Melting Point: -30ºC
-Vapor Pressure: 0.2 mm Hg ( 20 °C)
SPECIFICATION OF TETRAMETHYLGUANIDINE:
-Solubility: (20 °C) soluble
-Molar Mass: 115.17 g/mol
-Boiling Point: 162 °C (1013 hPa)
-Vapor Pressure: 0.26 hPa (25 °C)
-Flash Point: 50 °C
-Refractive Index: 1.4659 (20 °C, 589 nm)
-Explosion Limit: 1.0 - 7.5 %(V)
-Density: 0.92 g/cm3 (20 °C)
-pH: 12.7 (10 g/l, H2O, 25 °C)
-Ignition Point: 350 °C
-Hill Formula: C5H13N3
-Chemical Formula: [(CH3)2N]2C=NH
SOLUBILITY OF TETRAMETHYLGUANIDINE:
freely sol most organic solvents; sol water.
STORAGE OF TETRAMETHYLGUANIDINE:
It should be placed in cool and dry.
SYNONYM:
1,1,3,3-Tetramethylguanidine
80-70-6
Tetramethylguanidine
N,N,N',N'-Tetramethylguanidine
Guanidine, N,N,N',N'-tetramethyl-
tetramethyl guanidine
UNII-VEZ101E7ZU
MFCD00008323
VEZ101E7ZU
1,1,3,3-TETRAMETHYL GUANIDINE
1,1,3,3-tetramethyl-guanidine
n,n,n',n'-tetramethyl-guanidine
Guanidine, 1,1,3,3-tetramethyl-
1,1,3,3-Tetramethylguanidine, 99%
CCRIS 6689
tetramethyguanidine
Tetramethlguanidine
EINECS 201-302-7
tetramethyl-guanidine
NSC 148309
PubChem19325
ACMC-20aj0u
AI3-51030
N,N-1,1,3,3-TETRAMETHYLGUANIDINE
(Me2N)2C=NH
1,3,3-Tetramethylguanidine
SCHEMBL35686
N,N',N'-Tetramethylguanidine
Guanidine,1,3,3-tetramethyl-
DTXSID2058835
1, 1,3,3-tetramethylguanidine
1,1,3,3 tetramethyl guanidine
1,1,3,3,-tetramethylguanidine
1,1,3,3-tetra-methylguanidine
1,1,3,3-Tetramethylguayyniaine
n,n,n',n'-tetramethyl guanidine
IUPAC NAME:
1,1,3,3-Tetramethylguanidine
1,1,3,3-tetramethylguanidine
1,1,3,3-Tetramethylguanidine (TMG)
Guanidine, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethylguanidin
TMG
