PRODUCTS

TETRAMETHYLTHIURAM MONOSULFIDE (TMTM)

Tetramethylthiuram Monosulfide (TMTM) can be used for the research of fungal infection, bacterial infection and allergic contact dermatitis.
Tetramethylthiuram Monosulfide (TMTM) is used as an activator in the sulfur vulcanization of natural and butyl rubbers.
Tetramethylthiuram monosulfide (TMTM) can be used for the research of rubber and various biochemical studies.

CAS Number: 97-74-5
EC Number: 202-605-7
Molecular Formula: C6H12N2S3
Molecular Weight: 208.37 g/mol

SYNONYMS:
Tetramethylthiuram Monosulfide, Tetramethylthiuram Monosulphide, Bis(dimethylthiocarbamoyl) Sulfide, Bis(dimethylthiocarbamoyl) Sulphide, Thiocarbamyl Sulfide, Thiuram Monosulfide, Tetramethylthiuram Sulfide, TMTM, TS, Accelerator TS, Vulkacit TS, Monothiuram, Monosulfide Thiuram Accelerator, N1,N1,N3,N3-Tetramethyl-1,2,3-trithiodicarbonic diamide, N,N,N′,N′-Tetramethylthiuram monosulfide, Tetramethylthiuram monosulfide, 97-74-5, BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE, Unads, TMTM, Monothiuram, Mono-thiurad, Aceto TMTM, Thiuram MM, TMTMS, Tetramethylthiuram sulfide, Cyuram MS, Ekagom TM, Vulkacit ms, Vulkacit Thiuram MS, Pennac MS, Tetramethylthiuramide sulfide, Tetramethylthiuram monosulphide, Tetramethylthiurammonium sulfide, Tetramethylthiuramonosulfide, Vulkacit thiuram ms/C, Thiuram monosulfide, tetramethyl-, Tetramethyldithiocarbamic acid anhydrosulfide, DTXSID0021333, Monosulfure de tetramethylthiurame, N,N,N',N'-Tetramethylthiuram monosulfide, Bis(dimethylthiocarbamoyl)sulfide, Sulfide, bis((dimethylamino)thioxomethyl), Carbamic acid, dimethyldithio-, anhydrosulfide, Carbamodithioic acid, dimethyl-, anhydrosulfide, CP 2113, 01W430XXSQ, NSC-3400, NSC-4767, DTXCID801333, N,N-dimethyl[(dimethylcarbamothioyl)sulfanyl]carbothioamide, Sulfide, bis[(dimethylamino)thioxomethyl], N,N-dimethyl((dimethylcarbamothioyl)sulfanyl)carbothioamide, RefChem:569071, 202-605-7, Bis(dimethylthiocarbamyl) sulfide, Usaf ek-p-6255, Usaf B-32, dimethylcarbamothioyl N,N-dimethylcarbamodithioate, Bis(dimethylthiocarbamyl) monosulfide, Carbamic anhydride, tetramethyltrithio-, Sulfide, bis(dimethylthiocarbamoyl), NSC 3400, NSC 4767, MFCD00014870, Formamide, 1,1'-thiobis(N,N-dimethylthio-, Thiodicarbonic diamide ([(H2N)C(S)]2S), tetramethyl-, Sulfide, bis(dimethylthiocarbamoyl) (8CI), CHEMBL571700, NSC4767, NCGC00159424-02, NCGC00159424-04, Thionex rubber accelerator, Carbamic acid, anhydrosulfide, Thiodicarbonic diamide (((H2N)C(S))2S), tetramethyl-, Carbamodithioic acid, anhydrosulfide, N,N',N'-Tetramethylthiuram monosulfide, CAS-97-74-5, Formamide,1'-thiobis[N,N-dimethylthio-, C6H12N2S3, HSDB 2902, WLN: 1N1 & YUS & SYUS & N1 & 1, EINECS 202-605-7, BRN 1775650, UNII-01W430XXSQ, (dimethylamino)[(dimethylamino)thioxomethylthio]methane-1-thione, AI3-00984, Monosulfure de tetramethylthiurame [French], Perkacit TMTM, EC 202-605-7, N,N,N',N'-Tetramethyldicarbonotrithioic diamide, SCHEMBL23048, tetramethylthiuram-monosulfide, 4-04-00-00238 (Beilstein Handbook Reference), orb1217418, orb1305924, REQPQFUJGGOFQL-UHFFFAOYSA-, NSC3400, Tetramethylthiuram monosulfide, 97%, Thiodicarbonic diamide, tetramethyl-, Tox21_111656, Tox21_201554, Tox21_302880, BDBM50414949, BISDIMETHYLTHIOCARBAMYL SULFIDE, EBC-26204, s2432, SBB058588, AKOS015850780, BISDIMETHYLTHIOCARBAMYL SULPHIDE, Tox21_111656_1, DB14178, HY-W020246, Bis(dimethylaminethiocarbonyl)monosulfide, NCGC00159424-03, NCGC00159424-05, NCGC00256325-01, NCGC00259103-01, DA-68082, LS-13171, CS-0039286, NS00007980, ST50825572, E80911, N,N,N',N'-Tetramethyltrithiodicarbonic diamide, SBI-0654050.0001, T22438, BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE [HSDB], EN300-7719162, F601954, N,N,N',N'-Tetramethyldicarbonotrithioic diamide #, SR-01000944762, SR-01000944762-1, BRD-K36889451-001-01-1, Q27231461, Thiodicarbonic diamide ([(H2-N)C(S)]2-S), tetramethyl-, Thiodicarbonic diamide (((H2N)C(S))2S), N,N,N',N'-tetramethyl-, InChI=1/C6H12N2S3/c1-7(2)5(9)11-6(10)8(3)4/h1-4H3, Bis(dimethylthiocarbamoyl) sulfide, Tetramethylthiuram monosulfide, UNADS, TMTM, Thiodicarbonic diamide, tetramethyl-, Bis(dimethylthiocarbamyl) sulfide, UNADS, monex bis(dimethylthiocarbamoyl) sulfide (tmtm) thiuram monosulphides, Tetramethylthiuram monosulfide, Thiodicarbonic diamide ([(H2-N)C(S)]2-S), tetramethyl-, Aceto TMTM, Bis(dimethylthiocarbamoyl) sulfide, Bis(dimethylthiocarbamyl) monosulfide, Carbamic acid, dimethyldithio-, anhydrosulfide, Carbamic anhydride, tetramethyltrithio-, Carbamodithioic acid, dimethyl-, anhydrosulfide, Cyuram MS, Ekagom TM, Formamide, 1,1'-thiobis(N,N-dimethylthio-, Monex, Mono-Thiurad, Monothiuram, N,N,N',N'-Tetramethylthiuram monosulfide, Sulfide, bis(dimethylthiocarbamoyl), Sulfide, bis((dimethylamino)thioxomethyl), Tetramethyldithiocarbamic acid anhydrosulfide, Tetramethylthiuram sulfide, Tetramethylthiuramide sulfide, Thiuram monosulfide, tetramethyl-, Thiuram MM, TMTM, TMTMS, Unads, USAF EK-P-6255, USAF B-32, Vulkacit Thiuram MS, Monosulfure de tetramethylthiurame, Pennac MS, Tetramethylthiuramonosulfide, Vulkacit MS, Vulkacit thiuram ms/C, Perkacit TMTM, Thiodicarbonic diamide, tetramethyl-, NSC 3400, Tetramethylthiurammonium sulfide, NSC 4767, tetramethylthiuram monosulphide

Tetramethylthiuram Monosulfide (TMTM) is a light yellow to Yellow to Orange powder to crystaline
Tetramethylthiuram Monosulfide (TMTM) is an organosulfur compound with the chemical formula C5H12N2S2.
Tetramethylthiuram Monosulfide (TMTM) appears as a white to light yellow crystalline solid and is characterized by its relatively low solubility in water but good solubility in organic solvents.

Tetramethylthiuram Monosulfide (TMTM) features a thiuram disulfide structure, which contributes to its reactivity and effectiveness as a rubber accelerator.
Tetramethylthiuram Monosulfide (TMTM) is known for its ability to promote cross-linking in rubber, leading to improved mechanical properties.
Tetramethylthiuram Monosulfide (TMTM) plays a significant role in the rubber industry, contributing to the production of high-performance rubber materials.

Tetramethylthiuram Monosulfide (TMTM) is an accelerator found in the rubber industry.
Tetramethylthiuram Monosulfide (TMTM) is a thiuram compound.
Tetramethylthiuram Monosulfide (TMTM) presents as a white crystalline solid with a melting point of 111°C and a boiling point of 250°C.

As a highly reactive compound, Tetramethylthiuram Monosulfide (TMTM) has found application in synthesizing a diverse range of compounds.
Tetramethylthiuram Monosulfide (TMTM) has been instrumental in material development and investigating biochemical and physiological effects.
Tetramethylthiuram Monosulfide (TMTM)'s versatility has facilitated the development of novel materials and the exploration of biochemical and physiological effects.

The mechanism of action of Tetramethylthiuram Monosulfide (TMTM) involves inhibiting enzymes responsible for protein and nucleic acid synthesis.
By binding to the enzyme′s active site, Tetramethylthiuram Monosulfide (TMTM) hinders catalysis of the reaction.
Thus, Tetramethylthiuram Monosulfide (TMTM) effectively disrupts the enzyme′s function by occupying its active site and preventing the catalytic reaction.

Tetramethylthiuram monosulfide (TMTM) is an active compound.
Tetramethylthiuram monosulfide (TMTM) is an active compound.
Tetramethylthiuram monosulfide (TMTM) is an orally active microsomal monooxygenases inhibitor.

Tetramethylthiuram Monosulfide (TMTM) is an organosulfur compound with the formula ((CH3)2NCS)2S.
Tetramethylthiuram Monosulfide (TMTM) is a yellow solid that is soluble in organic solvents.
Tetramethylthiuram Monosulfide (TMTM) is the parent member of a large class of thiuram monosulfides.

Tetramethylthiuram Monosulfide (TMTM) is a sulfur-containing organosulfur compound belonging to the thiuram family of rubber vulcanization accelerators.
Tetramethylthiuram Monosulfide (TMTM) is classified as an ultra-fast accelerator and is widely used in sulfur curing systems for natural rubber and numerous synthetic elastomers.
Compared with tetramethylthiuram disulfide (TMTD), Tetramethylthiuram Monosulfide (TMTM) provides improved scorch safety while still delivering rapid vulcanization and excellent mechanical performance.

Tetramethylthiuram Monosulfide (TMTM) functions primarily as a secondary accelerator in combination with thiazoles or sulfenamides, although it may also be used as a primary accelerator in selected formulations.
Because it contains only one sulfur atom between the thiocarbamyl groups, Tetramethylthiuram Monosulfide (TMTM) contributes less available sulfur to the curing system than TMTD, allowing greater control over crosslink formation and reducing the risk of over-curing.
Tetramethylthiuram Monosulfide (TMTM) has become an important accelerator for manufacturers seeking balanced cure characteristics, excellent processing safety, and reliable long-term performance.

USES and APPLICATIONS of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Tetramethylthiuram Monosulfide (TMTM) is primarily used as a rubber accelerator in the vulcanization process, enhancing the elasticity and durability of rubber products.
Tetramethylthiuram Monosulfide (TMTM) is used as an accelerator and activator in the processing of natural rubber and butyl rubber.
Tetramethylthiuram Monosulfide (TMTM) reduces palmitic acid incorporation into microsomal phospholipids, disrupts microsomal membrane integrity, and impairs electron transport during oxygenation.

Tetramethylthiuram Monosulfide (TMTM) is used as a rubber accelerator.
Tetramethylthiuram Monosulfide (TMTM) is also applied in curing agents.
Tetramethylthiuram Monosulfide (TMTM) is widely used in rubber processing.

Tetramethylthiuram Monosulfide (TMTM) plays a role in fast curing systems.
Tetramethylthiuram Monosulfide (TMTM) is also applied in industrial goods.
Additionally, Tetramethylthiuram Monosulfide (TMTM) finds applications in specialty rubber and chemical industries.

Application of Tetramethylthiuram Monosulfide (TMTM): Rubber vulcanization accelerator
Tetramethylthiuram monosulfide (TMTM) can be used in rubber and various biochemical studies.
Tetramethylthiuram Monosulfide (TMTM) is primarily used as an ultra-fast secondary sulfur vulcanization accelerator in natural rubber and synthetic elastomer compounds.

Tetramethylthiuram Monosulfide (TMTM) is extensively employed in the production of automobile tires, truck tires, industrial belts, conveyor belts, hoses, seals, gaskets, O-rings, cable insulation, rubber-coated fabrics, footwear, molded rubber goods, vibration isolators, and numerous engineering rubber products.
Tetramethylthiuram Monosulfide (TMTM) is particularly useful in formulations requiring rapid curing with improved scorch safety compared with TMTD.

Tetramethylthiuram Monosulfide (TMTM) is frequently combined with MBT, MBTS, CBS, or other benzothiazole accelerators to optimize cure speed, crosslink density, mechanical properties, and processing efficiency.
Tetramethylthiuram Monosulfide (TMTM) is also utilized in latex compounds, adhesive formulations, rubber-coated textiles, and specialty elastomer products where controlled sulfur crosslinking is essential.
In high-performance industrial rubber compounds, Tetramethylthiuram Monosulfide (TMTM) contributes to improved production efficiency while maintaining excellent mechanical strength and long-term durability.

BENEFITS of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Tetramethylthiuram Monosulfide (TMTM) provides rapid sulfur vulcanization while offering better scorch safety than tetramethylthiuram disulfide.
This allows longer processing times during mixing, extrusion, and molding without significantly increasing the risk of premature vulcanization.
Tetramethylthiuram Monosulfide (TMTM) contributes to excellent tensile strength, tear resistance, resilience, elasticity, abrasion resistance, fatigue resistance, and compression set of vulcanized rubber.

Because it donates less sulfur than TMTD, Tetramethylthiuram Monosulfide (TMTM) helps produce a more controlled crosslink structure, resulting in improved heat aging resistance and reduced cure reversion.
Another significant advantage is Tetramethylthiuram Monosulfide (TMTM)'s excellent compatibility with numerous accelerator systems, allowing rubber compound formulators to tailor cure characteristics according to specific manufacturing requirements.
Tetramethylthiuram Monosulfide (TMTM) also demonstrates good storage stability, predictable curing performance, and low volatility, making it highly reliable for large-scale industrial production.

CHARACTERISTICS of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Tetramethylthiuram Monosulfide (TMTM) is considered an ultra-fast sulfur vulcanization accelerator with excellent scorch safety compared with tetramethylthiuram disulfide (TMTD).
Because Tetramethylthiuram Monosulfide (TMTM) contains only one sulfur bridge, it contributes less sulfur to the curing system and allows greater control over crosslink density and cure characteristics.
This feature makes Tetramethylthiuram Monosulfide (TMTM) particularly suitable for formulations where excessive sulfur donation from thiuram disulfides is undesirable.

Tetramethylthiuram Monosulfide (TMTM) exhibits excellent compatibility with natural rubber (NR), styrene-butadiene rubber (SBR), butadiene rubber (BR), nitrile rubber (NBR), chloroprene rubber (CR), and numerous sulfur-curable elastomers.
Tetramethylthiuram Monosulfide (TMTM) demonstrates outstanding synergistic effects when combined with benzothiazole accelerators such as MBT, MBTS, and CBS, enabling rapid vulcanization while maintaining adequate processing safety.

Tetramethylthiuram Monosulfide (TMTM) provides excellent storage stability, low volatility, and consistent curing behavior under a wide range of processing conditions.
Tetramethylthiuram Monosulfide (TMTM)'s controlled sulfur contribution results in vulcanized rubber with uniform crosslink distribution, excellent elasticity, and improved resistance to reversion compared with some higher sulfur-donating accelerators.

SYNTHESIS AND STRUCTURE of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Tetramethylthiuram Monosulfide (TMTM) is prepared by desulfuration of tetramethylthiuram disulfides with triphenylphosphine or cyanide:
(Me2NCSS)2 + PPh3 → (Me2NCS)2S + SPPh3
According to X-ray crystallography, the molecule consists of two planar (CH3)2NCS subunits joined by a sulfide.
The dihedral angle between the subunits is close to 90°.

STORAGE CONDITION of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Store Tetramethylthiuram Monosulfide (TMTM) in a cool, dry place.
Keep Tetramethylthiuram Monosulfide (TMTM) the container closed when not in use.

PHYSICAL and CHEMICAL PROPERTIES of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
Appearance: Pale yellow to light yellow powder, granules, or crystalline solid.
Physical State: Solid.
Color: Pale yellow to yellow.
Odor: Slight characteristic sulfur-like odor.
Molecular Formula: C6H12N2S3.
Molecular Weight: 208.37 g/mol.
Density: Approximately 1.30–1.40 g/cm³ at 20°C.
Melting Point: Approximately 105–110°C.
Boiling Point: Not applicable; decomposes before boiling.
Flash Point: Approximately 150–170°C (reported values vary depending on the test method).
Autoignition Temperature: Approximately 300°C (estimated).

Vapor Pressure: Extremely low at ambient temperature.
Volatility: Low.
Water Solubility: Practically insoluble (less than 20 mg/L at 25°C).
Solubility in Organic Solvents: Soluble in acetone, chloroform, benzene, carbon disulfide, toluene, ethyl acetate, and many aromatic hydrocarbons.
Partition Coefficient (log Kow): Approximately 2.0–2.7.
pH: Not applicable (insoluble in water).
Thermal Stability: Stable under recommended storage conditions.
Chemical Stability: Stable during normal industrial handling.
Hygroscopicity: Low.

Dust Explosion Hazard: Fine dust may form combustible dust-air mixtures.
Oxidizing Properties: Not classified as oxidizing.
Explosive Properties: Not classified as explosive.
Decomposition Products: Carbon monoxide (CO), carbon dioxide (CO₂), sulfur oxides (SOx), nitrogen oxides (NOx),
carbonyl sulfide (COS), hydrogen sulfide (H₂S), and sulfur-containing organic compounds.
Reactivity: Incompatible with strong oxidizing agents, strong acids, and highly reactive chemicals.
Chemical Name: Tetramethylthiuram Monosulfide
Common Name: TMTM
IUPAC Name: Bis(dimethylthiocarbamoyl) sulfide
CAS Number: 97-74-5

EC Number: 202-605-7
Molecular Formula: C6H12N2S3
Molecular Weight: 208.37 g/mol
Chemical formula: C6H12N2S3
Molar mass: 208.36 g·mol−1
Density: 1.39
Melting point: 107 °C (225 °F; 380 K)
Linear Formula: ((H3C)2NCS)2S
CAS Number: 97-74-5
Molecular Weight: 208.37
NACRES: NA.22
PubChem Substance ID: 24880353

UNSPSC Code: 12352100
EC Number: 202-605-7
MDL number: MFCD00014870
Assay: 97%
Physical state: solid
Form: powder
Colour: yellow
Odour: No data available
Melting point/ range: 107 - 111 °C
Method: lit.
Boiling point: No data available

Flammability: No data available
Upper explosion limit / Upper flammability limit: No data available
Lower explosion limit / Lower flammability limit: No data available
Flash point: 156 °C
Method: closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity, dynamic: No data available
Viscosity, kinematic: No data available
Flow time: No data available

Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 1,17
Vapour pressure: No data available
Relative density: No data available
Density: 1,370 g/cm3
Relative vapour density: No data available
Other information
Explosives: No data available
Oxidizing properties: No data available
Burning rate: No data available
Evaporation rate: No data available
Molecular weight: 208,37 g/mol
CAS: 97-74-5

IUPAC Name: N,N-dimethyl[(dimethylcarbamothioyl)sulfanyl]carbothioamide
Molecular Formula: C6H12N2S3
InChI Key: REQPQFUJGGOFQL-UHFFFAOYSA-N
SMILES: CN(C)C(=S)SC(=S)N(C)C
Molecular Weight (g/mol): 208.36
Appearance (Color): Yellow
Assay (HPLC): ≥96.0%
Melting Point (clear melt): 104.0-114.0°C
Form: Powder
Physical State: Solid
Storage: Store at room temperature
Melting Point: 107-111° C (lit.)
Density: 1.37 g/cm3

FIRST AID MEASURES of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of TETRAMETHYLTHIURAM MONOSULFIDE (TMTM):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available