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Tetrasodium (1-hydroxyethylidene) bisphosphonate is a cost effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents.
Tetrasodium (1-hydroxyethylidene) bisphosphonate further shows good stability in presence of chlorine as well as corrosion inhibition properties in presence of zinc and other phosphates.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is a chemical compound commonly known as tetrasodium etidronate.
CAS Number: 3794-83-0
Molecular Formula: C2H9NaO7P2
Molecular Weight: 230.02
EINECS Number: 223-267-7
3794-83-0, Tetrasodium etidronate, (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt, Phosphonic acid, (1-hydroxyethylidene)bis-, tetrasodium salt, etidronate tetrasodium, tetrasodium;1,1-diphosphonatoethanol, CZZ9T1T1X4, Tarpinel 4NL, Turpinal 4NL, Sequion 10Na4, Defloc EN 43, Dequest 2016, EINECS 223-267-7, UNII-CZZ9T1T1X4, Tetrasodium (1-hydroxyethylidene)bisphosphonate, Tetrasodium 1-hydroxyethylidene-1,1-diphosphonate, (1-Hydroxyethylidene)diphosphonic acid, tetrasodium salt, Ethane-1-hydroxy-1,1-diphosphonic acid, tetrasodium salt, 1-Hydroxyethylidene-1,1-diphosphonic acid, tetrasodium salt, EC 223-267-7, Tetrasodium 1-hydroxyethane-1, 1-diphosphonate, (1-Hydroxyethylidene)bisphosphonic acid, tetrasodium salt, DTXSID7029663, DIPHOSPHONIC ACID, (1-HYDROXYETHYLIDENE)-, TETRASODIUM SALT, MFCD01729922, TETRASODIUM ETIDRONATE [INCI], AKOS015899696, ETIDRONATE TETRASODIUM [WHO-DD], AS-15257, sodium-1-hydroxyethane-1,1-diphosphonate, Tetrasodium 1-hydroxyethylidenediphosphonate, FT-0689101, NS00078309, sodium 1-hydroxyethane-1,1-diyldiphosphonate, F71280, 1-hydroxyethane-1,1-diphosphonic acid tetrasodium salt, Q27275911, tetrasodium (1-hydroxyethane-1,1-diyl)bis(phosphonate), Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4).
Tetrasodium (1-hydroxyethylidene) bisphosphonate is a derivative of the bisphosphonate family, which are compounds containing two phosphonate groups.
The chemical structure of tetrasodium etidronate includes four sodium ions (tetrasodium) and the bisphosphonate molecule with a hydroxyethylidene group.
Tetrasodium (1-hydroxyethylidene) bisphosphonate, is a non-nitrogenous bisphosphonate used as a medication, detergent, water treatment, and cosmetic.
Tetrasodium (1-hydroxyethylidene) bisphosphonate was patented in 1966 and approved for medical use in 1977.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is a functional group that is used in the textile industry as an antimicrobial treatment.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is often used to reduce viscosity and increase active substances in detergents, shampoos, and other personal care products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate has been shown to modulate matrix metalloproteinase activity in vitro.
In addition, Tetrasodium (1-hydroxyethylidene) bisphosphonate is often used as a matrix metalloproteinase inhibitor in the pharmaceutical industry.
The chemical structure of Tetrasodium (1-hydroxyethylidene) bisphosphonate contains both aromatic hydrocarbon and fatty acid functional groups.
Tetrapotassium (1-hydroxyethylidene)bisphosphonate is soluble in water, but insoluble in organic solvents such as alcohols or ethers.
This functional group also has antimicrobial properties due to
Tetrasodium (1-hydroxyethylidene) bisphosphonate combines antiwear performance with scale-inhibition and chelating properties for extended fluid and tool life.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be used to prepare metal surfaces for final finishing, and in plating baths to control metal ion contamination.
Tetrasodium (1-hydroxyethylidene) bisphosphonates are also widely used for cooling water treatment, metal cleaners, textile finishing and oil field drilling applications.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used mainly in laundry detergents; Used to make ceramics, cement, washing-cleaning products, metal surface treatment products (including those for galvanizing and electroplating), paints-coatings-thinners, agrochemicals, in industrial water treatment, oilfield water systems, the textile and paper industries, water desalination systems, and in the generic formulation and production of a wide range of other products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is not primarily used as a leavening agent in the food industry.
Instead, Tetrasodium (1-hydroxyethylidene) bisphosphonate has found applications in personal care and household products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is commonly used in the cosmetic and personal care industry.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is often included in skincare and haircare products for its water-softening and chelating properties.
Chelating agents help to bind metal ions, improving the stability and performance of the product.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is effective in reducing the effects of hard water.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can bind to metal ions found in hard water, preventing them from interfering with the performance of soaps and detergents.
As a result, Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in some formulations for bath products and household cleaners.
In addition to its role in hard water treatment, Tetrasodium (1-hydroxyethylidene) bisphosphonate is sometimes used as an antiscalant in industrial water treatment processes to inhibit the formation of scale deposits.
Tetrasodium (1-hydroxyethylidene) bisphosphonate acts as a chelating agent by forming stable complexes with metal ions, helping to improve the stability and shelf life of cosmetic and personal care products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be directly incorporated into formulations without preparation of a separate thickener solution.
Viscosity is developed simply by adjusting the pH on the alkaline side with any base.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is supplied as a low viscosity emulsion and therefore is easy to handle.
Tetrasodium (1-hydroxyethylidene) bisphosphonate contains carboxylic groups that immediately swell upon neutralization.
The salt form of Tetrasodium (1-hydroxyethylidene) bisphosphonate also stabilizes heavy-duty liquid cleaners that contain high levels of nonionic surfactants and alkaline builders, by preventing the coalescence of surfactant particles and the separation of other components.
Tetrasodium (1-hydroxyethylidene) bisphosphonate, used in cleaning detergents, treatment of cooling water for boilers and water pipes for oil fields, at 250 °C (iron, copper, zinc forms stable and stable complexes with ions), dissolves oxides on the metal surface, is a hydrogen peroxide stabilizer.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is a cost effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents.
Tetrasodium (1-hydroxyethylidene) bisphosphonate further shows good stability in presence of chlorine as well as corrosion inhibition properties in presence of zinc and other phosphates.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is known for its water-softening properties.
In personal care products like shampoos and soaps, it can enhance lathering and improve the performance of these products in hard water environments.
Tetrasodium (1-hydroxyethylidene) bisphosphonate, the parent compound of tetrasodium etidronate, has been studied for its potential applications in dentistry.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is ability to inhibit the formation of dental calculus (tartar) makes it a candidate for oral care formulations.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is utilized in some industrial processes, such as water treatment, to prevent the formation of scale deposits.
The compound's chelating properties help to sequester metal ions that could contribute to scaling.
In some household cleaning products, Tetrasodium (1-hydroxyethylidene) bisphosphonate may be included to improve the effectiveness of the formulation by chelating metal ions and preventing them from interfering with cleaning agents.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can act as a stabilizer in cosmetic and personal care formulations.
Tetrasodium (1-hydroxyethylidene) bisphosphonate helps maintain the stability of products by preventing the degradation of certain ingredients over time.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is sometimes used as a reagent in certain synthetic processes in laboratories and industrial settings.
Density: 2.074[at 20℃]
vapor pressure:0Pa at 25℃
solubility:Aqueous Acid (Slightly), Water (Sparingly)
pka: 2.18[at 20 ℃]
form: Solid
color: White to Off-White
Water Solubility: 774g/L at 20℃
Stability: Hygroscopic
LogP: -3 at 23℃
Tetrasodium (1-hydroxyethylidene) bisphosphonate is known for its compatibility with a wide range of cosmetic and personal care ingredients.
This makes Tetrasodium (1-hydroxyethylidene) bisphosphonate a versatile choice for formulators looking to achieve specific product characteristics.
In some formulations, Tetrasodium (1-hydroxyethylidene) bisphosphonate may be used synergistically with other chelating or stabilizing agents to enhance its overall performance and effectiveness in complex systems.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is occasionally utilized in cosmetic products, including perfumes and fragrances, to help stabilize the formulation and prevent changes in fragrance profiles over time.
While Tetrasodium (1-hydroxyethylidene) bisphosphonate itself is not commonly used for pH adjustment, its presence in a formulation can contribute to pH stability by chelating metal ions that might otherwise influence the pH.
Apart from its role in preventing scale deposits, Tetrasodium (1-hydroxyethylidene) bisphosphonate is employed in certain industrial water treatment applications to enhance water quality and prevent issues related to metal ion content.
Tetrasodium (1-hydroxyethylidene) bisphosphonate may be included in some household and industrial cleaning products to improve their performance by sequestering metal ions that can interfere with cleaning agents.
In hair care products, Tetrasodium (1-hydroxyethylidene) bisphosphonate can contribute to the removal of mineral deposits from hair, preventing dullness and improving the overall appearance of the hair.
Tetrasodium (1-hydroxyethylidene) bisphosphonate exhibits stability under alkaline conditions, making it suitable for use in formulations where a higher pH is desired.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses of Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following products: washing & cleaning products, fertilisers, cosmetics and personal care products, coating products and water softeners.
Other release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is commonly used in the formulation of bath products, such as bath salts and bath bombs.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is ability to chelate metal ions helps prevent mineral deposits in water, providing a more enjoyable bathing experience.
In addition to its role in personal care products, Tetrasodium (1-hydroxyethylidene) bisphosphonate is sometimes included in laundry detergents and other household cleaning products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate contributes to the stability and performance of these formulations.
Tetrasodium (1-hydroxyethylidene) bisphosphonate's ability to form stable complexes with metal ions makes it useful in various industrial processes where the presence of metal ions can interfere with reactions or product quality.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is known for its compatibility with surfactants, making it a versatile ingredient in formulations where emulsification and dispersion of various components are important.
One of the key mechanisms of action for etidronate compounds, including Tetrasodium (1-hydroxyethylidene) bisphosphonate, is their ability to chelate calcium ions.
This property is relevant in applications where the inhibition of calcium-related processes is beneficial.
Tetrasodium (1-hydroxyethylidene) bisphosphonate's sequestration properties extend to a variety of metal ions, including magnesium, iron, and others, making it valuable in formulations where the presence of these ions needs to be controlled.
Uses Of Tetrasodium (1-hydroxyethylidene) bisphosphonate:
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in method for applying a gel compound on a surface of a device and corresponding coated device.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following products: washing & cleaning products, fertilisers, coating products, cosmetics and personal care products, water softeners, air care products and polishes and waxes.
Other release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal), industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting), in the production of articles and in processing aids at industrial sites.
Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), wood (e.g. floors, furniture, toys), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Tetrasodium (1-hydroxyethylidene) bisphosphonate is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.
Tetrasodium (1-hydroxyethylidene) bisphosphonates primarily reduce osteoclastic activity, which prevents bone resorption, and thus moves the bone resorption/formation equilibrium toward the formation side and hence makes bone stronger on the long run.
Tetrasodium (1-hydroxyethylidene) bisphosphonate, also prevents bone calcification. For this reason, other bisphosphonates, such as alendronate, are preferred when fighting osteoporosis.
To prevent bone resorption without affecting too much bone calcification, Tetrasodium (1-hydroxyethylidene) bisphosphonate must be administered only for a short time once in a while, for example for two weeks every 3 months.
When given on a continuous basis, say every day, etidronate will altogether prevent bone calcification.
This effect may be useful and Tetrasodium (1-hydroxyethylidene) bisphosphonate is in fact used this way to fight heterotopic ossification.
But in the long run, if used on a continuous basis, it will cause osteomalacia.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following products: water softeners, washing & cleaning products, air care products, fertilisers, polishes and waxes, cosmetics and personal care products and coating products.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following areas: agriculture, forestry and fishing and building & construction work.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used for the manufacture of: and textile, leather or fur.
Other release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used as a retardant in concrete, scale and corrosion inhibition in circulating cool water system, oil field and low-pressure boilers in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.
In the light woven industry, Tetrasodium (1-hydroxyethylidene) bisphosphonate is used as detergent for metal and nonmetal.
In dyeing industry, Tetrasodium (1-hydroxyethylidene) bisphosphonate is used as peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, Tetrasodium (1-hydroxyethylidene) bisphosphonate is used as chelating agent.
The dosage of 1–10 mg/L is preferred as scale inhibitor, 10–50 mg/L as corrosion inhibitor, and 1000–2000 mg/L as detergent.
Usually, Tetrasodium (1-hydroxyethylidene) bisphosphonate is also used together with polycarboxylic acid (superplasticizer), in which it acts as reducing agent.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following products: pH regulators and water treatment products, washing & cleaning products, fertilisers, coating products, laboratory chemicals, leather treatment products, textile treatment products and dyes, cosmetics and personal care products, paper chemicals and dyes, polishes and waxes and water softeners.
Release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate can occur from industrial use: formulation of mixtures.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following products: water softeners, washing & cleaning products, pH regulators and water treatment products and water treatment chemicals.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and mining.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used for the manufacture of: textile, leather or fur, pulp, paper and paper products, metals, fabricated metal products, machinery and vehicles and furniture.
Release to the environment of Tetrasodium (1-hydroxyethylidene) bisphosphonate can occur from industrial use: in processing aids at industrial sites and in the production of articles.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in soap formulations to enhance lathering and improve performance in hard water.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be found in hair care products to soften water, prevent mineral buildup on hair, and enhance the effectiveness of cleansing agents.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is often included in bath salts, bath bombs, and other bath products to improve solubility and reduce mineral deposits in bathwater.
Tetrasodium (1-hydroxyethylidene) bisphosphonate may be used in various skincare formulations, such as creams and lotions, to provide stability and prevent changes in texture or appearance.
Tetrasodium (1-hydroxyethylidene) bisphosphonate can be used to stabilize fragrances in perfumes and other scented products.
Inclusion in dishwashing detergents helps prevent scale deposits and improve the overall effectiveness of the detergent.
Tetrasodium (1-hydroxyethylidene) bisphosphonate contributes to water softening in laundry detergents, enhancing cleaning performance.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is used in industrial water treatment processes to prevent the formation of scale deposits in pipes and machinery.
Tetrasodium (1-hydroxyethylidene) bisphosphonate may be included in all-purpose cleaners to improve the cleaning action and reduce the impact of hard water on cleaning efficiency.
In some formulations, Tetrasodium (1-hydroxyethylidene) bisphosphonate compounds are studied for their potential role in preventing dental calculus (tartar) buildup.
Tetrasodium (1-hydroxyethylidene) bisphosphonate may be used in the textile industry for certain processes where water hardness needs to be controlled.
Tetrasodium (1-hydroxyethylidene) bisphosphonate is chelating properties make tetrasodium etidronate useful in certain industrial applications where metal cleaning is required.
Safety Profile Of Tetrasodium (1-hydroxyethylidene) bisphosphonate:
In concentrated forms or when handling the pure substance, Tetrasodium (1-hydroxyethylidene) bisphosphonate can potentially cause skin and eye irritation.
Tetrasodium (1-hydroxyethylidene) bisphosphonate's important to use proper protective equipment, such as gloves and goggles, when working with undiluted forms of the compound.
Inhalation of dust or aerosolized particles of Tetrasodium (1-hydroxyethylidene) bisphosphonate may irritate the respiratory system.
Adequate ventilation and respiratory protection should be used in situations where dust exposure is possible.
While not typically a concern in consumer products, ingestion of concentrated forms of Tetrasodium (1-hydroxyethylidene) bisphosphonate can be harmful.
Tetrasodium (1-hydroxyethylidene) bisphosphonate's essential to keep the substance away from the reach of children and avoid accidental ingestion.
