Quick Search
Tetrasodium EDDS refers to the fully neutralized sodium salt of ethylenediamine-N,N′-disuccinic acid (Tetrasodium EDDS), an aminopolycarboxylic acid that functions primarily as a chelating or complexing agent.
Tetrasodium EDDS is structurally related to EDTA and contains two nitrogen atoms and four carboxylic acid groups capable of coordinating metal ions.
Tetrasodium EDDS is very commonly supplied as the trisodium salt rather than the tetrasodium salt.
CAS Number: 64-02-8
Molecular Formula: C10H12N2Na4O8
Molecular Weight: 380.17
EINECS Number: 200-573-9
Synonyms: Edetate sodium, Sodium edetate, EDTA tetrasodium, EDTA sodium, Sodium EDTA, Calsol, EDTA tetrasodium salt, Versene 100, Endrate tetrasodium, Sequestrene, EDTA, tetrasodium, Tetrine, Syntes 12A, Na4EDTA, Trilon B, Tetrasodium ethylenediaminetetraacetate, Ergon, Versene powder, Versene 220, Aquamoline BC, Nervanaid B, Nullapon B, Kutrilon CS, Natrium aedeticum, Clewat T, Celon H, Ergon B, Celon IS, Questex 4, Sequestrene Na 4, Distol 8, Hamp-ene Na4, Nervanaid B liquid, Nullapon BFC Xonc, Perma kleer 100, Tetrasodium salt of EDTA, Versene FE 3, Nullapon BF-12, Nullapon BF-78, Warkeelate PS-42, Warkeelate PS-43, Clewat S 2, Nullapon BFC Liquid, Cheelox BF-12, Cheelox BF-13, Cheelox BF-78, Cheelox BR-33, Chelest 400, Kemplex 100, Nervanaid, Nullapo, Sodium (edetate de), Chelon 100, Perma kleer tetra CP, Caswell No. 846, Hamp-ene 100S, Hamp-ene 215, Hamp-ene 220, Tetrasodium salt EDTA, SODIUM ETHYLENEDIAMINETETRAACETATE, Nullapon BFC Xonc Beads, Perma kleer 50 crystals, Versene powder tetra sodium, CCRIS 6797, Edetate, HSDB 5003, edetate tetrasodium, EINECS 200-573-9, Tetrasodium ethylenediaminetetracetate, Sodium ethylenediaminetetraacetic acid, UNII-MP1J8420LU, EPA Pesticide Chemical Code 039107, MP1J8420LU, AI3-17182, Ethylene diamine tetraacetic acid sodium salt, Sodium salt of ethylenediaminetetraacetic acid, Tetranatrium ethylendiamintetraacetat, Ethylenediaminetetraacetic acid, tetrasodium salt, Tetrasodium salt of ethylenediaminetetracetic acid, N,N'-Ethylenediaminediacetic acid tetrasodium salt, Tetrasodium ethylene diamine tetraacetate, EC 200-573-9, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) tetrasodium salt, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, tetrasodium salt, Cheladrate, Disodium versene, Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt, Kiresuto B, Metaquest B, Chelaplex III, Chelest B, Diso-Tate, Komplexon III, Chelaton III, Clewat N, Versene NA, Chelaton 3, Disodium versenate, Edathamil disodium, Trilon BD, Triplex III, Versene Na2, Zonon D, Dotite 2NA, Selekton B 2, Disodium sequestrene, Disodium tetracemate, Mavacid ED 4, Versonol 120, Chelest 200, Sequestrene sodium 2, Veresene disodium salt, EDETATE SODIUM (II), EDETATE SODIUM [II], Disodium salt of EDTA, E.D.T.A. disodique, Acetic acid, (ethylenedinitrilo)tetra-, sodium salt, Perma Kleer Di Crystals, Edetic acid disodium salt, UNII-8NLQ36F6MM, TETRASODIUM EDETATE (MART.), TETRASODIUM EDETATE [MART.], CCRIS 3658, Dinatrium ethylendiamintetraacetat, HSDB 8013, NSC 2760, EINECS 205-358-3, Perma kleer 50 crystals disodium salt, Disodium ethylenediaminetetraacetic acid, CBC 50152966, Disodium diacid ethylenediaminetetraacetate, DR-16133, Ethylenediaminetetraacetate, disodium salt, AI3-18049, Disodium (ethylenedinitrilo)tetraacetic acid, Disodium dihydrogen ethylenediaminetetraacetate, EC 205-358-3, Disodium dihydrogen(ethylenedinitrilo)tetraacetate, Disodium ethylenediamine-N,N,N',N'-tetraacetate, Nervanid B, Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine), ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt, RefChem:5785, Ethylenediamine sodium tetracetate, 200-573-9, Ethylene diamine tetraacetic acid, disodium salt, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt, 64-02-8, Ethylenediaminetetraacetic acid tetrasodium salt, TETRASODIUM EDTA, Tetrasodium edetate, Edetate Sodium [USAN], Sodium 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:4), MFCD00012460, Aquamollin, Irgalon, Komplexon, Nullapon, Questex, Tetracemin, Tyclarosol, Distol, Edetate sodium (USAN), Kalex, Natrii edetas, Versene beads, Versene flake, Sequestrene ST, Metaquest C, Syntron B, Cheelox BF, Conigon BC, Nullapon BFC, Sequestrene 30A, Celon E, Nervanaid-B liquid, Warkeelate S-42, Chemcolox 200, Versene 67, Perma-kleer 100, Ethylene Diamine Tetraacetic Acid Tetrasodium Hydrate, Warkeelate PS-47, Edathanil tetrasodium, Perma-kleer tetra cp, Hamp-ene 100, Tetracemate tetrasodium, Chemcolox 240 powder, edta tetrasodium salt hydrate, tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate, Edetic acid tetrasodium salt, 8013-51-2, 0.1M Sodium edetate, Ethylenediaminetetraacetic acid sodium salt, Tetrasodium (ethylenedinitrilo)tetraacetate, C10H12N2Na4O8, Tetranatrium ethylendiamintetraacetat [Czech], Ethylenebis(iminodiacetic acid) tetrasodium salt, (Ethylenedinitrilo)tetraacetic acid tetrasodium salt, Tetrasodium ethylenediamine-N,N,N',N'-tetraacetate, Tetrasodium(ethylenedinitrilo)tetraacetate, EDTA 4Na, EDETATE [VANDF], 7379-28-4, SCHEMBL906, Tetrasodium ethylenediaminetetraacetate hydrate, EDETATE SODIUM [HSDB], EDETATE SODIUM [VANDF], Tetrasodium edetate [WHO-DD], CHEMBL2104344, DTXSID3026350, EDTA TETRASODIUM [VANDF], SODIUM EDETATE [WHO-DD], EDTA TETRASODIUM SALT [MI], SODIUM EDETATE [GREEN BOOK], 98% (Loss on drying</=10%), Glycine, N,N'-1,2-ethanediylbis(N-carboxymethyl-, tetrasodium salt, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), tetrasodium salt, AKOS015960370, DB13404, AC-10617, DA-53047, DB-257076, E0099, E0565, NS00077223, ST51037250, sodium salt of ethylenediamine tetracetic acid, D03946, E75734, ethylenediamine tetraacetic acid tetrasodium salt, ethylenediaminetetraacetic acid tetra sodium salt, F053299, Q27284152, Ethylenediamine tetraacetic acid tetrasodium salt, 86-88%, tetrasodium 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, TETRASODIUM 2-[2-(BIS(CARBOXYLATOMETHYL)AMINO)ETHYL-(CARBOXYLATOMETHYL)AMINO]ACETATE, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, sodium salt, sodium salt, sodium salt, sodium salt, ETHYLENEDIAMINETETRAACETIC ACID TETRASOD IUM SALT PURE;ETHYLENEDIAMINETETRAACETIC ACID TETRA-SO DIUM SALT TETRAH.;EDTA.Na4.2H2O;Ethylenediaminetetraaceticacid,tetrasodiumsaltdihydrate,99+%;Ethylenediamine-N,N,N',N'-tetraaceticacid, tetrasodiumsalt, tetrahydrate, ETHYLENEDIAMINETETRAACETICACIDTETRASODIUMSALT, REAGENT, ETHYLENEDINITRILOTETRACETICACIDTETRASODIUMSALT, ETHYLENE-DIAMINO-TETRA-ACETIC-ACID-TETRA-SODIUMSALT
Tetrasodium EDDS while technical literature also describes the fully neutralized tetrasodium ethylenediamine disuccinate (Na₄Tetrasodium EDDS).
The free-acid form of Tetrasodium EDDS has the molecular formula C₁₀H₁₆N₂O₈ and a molecular weight of approximately 292.24 g/mol.
Tetrasodium EDDS CAS number is 20846-91-7, while the corresponding sodium salts have different compositions and identifiers depending on their degree of neutralization.
Tetrasodium EDDS contains an ethylenediamine backbone connected to two succinic acid-derived units.
Tetrasodium EDDS therefore provides multiple carboxylate donor groups together with nitrogen donor atoms that can coordinate metal cations and form stable soluble complexes.
The chelating ability of Tetrasodium EDDS allows it to bind a variety of metal ions, including transition metals such as iron and copper, as well as other multivalent metal ions.
This metal-binding behavior is the main reason Tetrasodium EDDS salts are incorporated into formulations where control of trace metals is required.
One of the major advantages associated with [S,S]-Tetrasodium EDDS is its relatively favorable biodegradability compared with conventional EDTA.
The [S,S] stereoisomer has been reported to undergo substantially faster biodegradation than the R,R and meso forms, which has contributed to interest in Tetrasodium EDDS as a more environmentally compatible chelating agent.
Tetrasodium EDDS is therefore considered part of a newer generation of aminopolycarboxylate chelating agents developed partly in response to concerns regarding the environmental persistence of conventional chelators.
Tetrasodium EDDS has been investigated as an alternative to EDTA in detergents, environmental remediation, agriculture, cosmetics, pulp and paper processing, and other industrial applications.
The sodium salt is highly water-soluble, which is particularly useful when Tetrasodium EDDS is incorporated into aqueous formulations.
A reported trisodium Tetrasodium EDDS material has water solubility of at least 1000 g/L at 20 °C and pH 7, illustrating the strong suitability of Tetrasodium EDDS sodium salts for water-based systems.
Tetrasodium EDDS also has several stereochemical forms because the molecule contains two chiral centers.
Among these forms, [S,S]-Tetrasodium EDDS is particularly important commercially and environmentally because of its favorable biodegradation characteristics.
In industrial formulations, Tetrasodium EDDS sodium salts can help control trace metal ions that would otherwise catalyze oxidation, discoloration, decomposition, or unwanted side reactions.
This makes Tetrasodium EDDS useful as a stabilizing and sequestering component in products where metal-ion control is important.
Tetrasodium EDDS should therefore be understood primarily as a water-soluble metal-ion chelating agent rather than as a conventional surfactant or solvent.
Its combination of strong metal complexation, high water compatibility, and the favorable biodegradability of the [S,S] form makes Tetrasodium EDDS an important alternative chelating technology for industrial and formulation applications.
Tetrasodium EDDS has been studied in anion-exchange and adsorption systems for the treatment of metal-containing aqueous streams.
In these processes, the chemical form of the metal–Tetrasodium EDDS complex becomes important because complex formation can influence how readily the species interacts with an ion-exchange resin or other sorbent.
Another area of interest is agricultural micronutrient management.
Tetrasodium EDDS can complex essential metal ions and has been investigated for improving the delivery and availability of metals such as iron in agricultural systems.
Tetrasodium EDDS has also been investigated in anaerobic digestion systems where trace-metal availability can influence biological activity.
Research has demonstrated that Fe–Tetrasodium EDDS formation can help maintain iron in soluble and bioavailable forms under sulfide-containing conditions.
The synthesis and production of [S,S]-Tetrasodium EDDS have additionally attracted research interest because biological and enzymatic production routes have been investigated.
Fermentation and enzymatic approaches are being explored as alternatives for producing the biodegradable stereoisomer on a larger scale.
Melting point: >300 °C(lit.)
Density Apparent density: 6.9 lb/gallon
storage temp.: 2-8°C, sealed storage, away from moisture
solubility: H2O: 0.1 g/mL, clear, colorless
form: Crystalline Powder
color: White
Stability: Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions: CHELATING
InChI: InChI=1S/C10H16N2O8.4Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;/q;4*+1/p-4
InChIKey: UEUXEKPTXMALOB-UHFFFAOYSA-J
SMILES: [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-]
LogP: -0.434 (est)
Tetrasodium EDDS is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash.
Tetrasodium EDDS has a highly functionalized structure containing multiple carboxylate groups and nitrogen donor atoms, allowing the molecule to coordinate metal ions through several binding sites.
Tetrasodium EDDS multidentate coordination behavior is responsible for the strong complexation properties associated with Tetrasodium EDDS-based chelating agents.
Tetrasodium EDDS is considered a structural isomer of EDTA because both compounds contain the same types of elemental components but have different arrangements of their functional groups.
Tetrasodium EDDS structural difference gives Tetrasodium EDDS a distinct coordination profile and contributes to its biodegradation behavior.
Tetrasodium EDDS molecule contains two stereogenic centers and can therefore occur as different stereoisomeric forms.
The principal configurations discussed in the literature are the [S,S], [R,R], and mixed [R,S]/[S,R] forms.
The [S,S] form is particularly important because it combines strong metal-binding ability with comparatively rapid biodegradation.
Studies have shown that [S,S]-Tetrasodium EDDS can be readily degraded by activated sludge, whereas the [R,R] form is considerably more resistant to biodegradation.
This stereochemical difference is significant when evaluating Tetrasodium EDDS as an environmentally preferable alternative to persistent chelating agents.
The biodegradation rate of Tetrasodium EDDS should therefore not be considered identical for every stereoisomer or commercial composition.
Tetrasodium EDDS can form complexes with a broad range of metal ions, including nutritionally important metals and potentially toxic heavy metals.
The resulting metal-Tetrasodium EDDS complexes can alter the solubility, mobility, and chemical availability of the coordinated metal.
This metal-binding behavior is particularly useful when a formulation needs to prevent uncontrolled reactions caused by trace metal ions.
By keeping metals in a coordinated form, Tetrasodium EDDS can influence processes such as oxidation, precipitation, and metal-catalyzed degradation.
The environmental behavior of Tetrasodium EDDS is strongly connected to its metal-complexing ability.
Free [S,S]-Tetrasodium EDDS can biodegrade relatively rapidly, while the biodegradation behavior of individual metal-Tetrasodium EDDS complexes can vary considerably depending on the metal involved.
Tetrasodium EDDS has consequently attracted attention as a biodegradable alternative to conventional persistent chelating agents such as EDTA.
Tetrasodium EDDSs combination of metal sequestration and biodegradability has encouraged research into applications involving detergents, soil remediation, agriculture, and industrial water treatment.
Tetrasodium EDDS is particularly interesting in environmental remediation because Tetrasodium EDDS can increase the mobility of metals that are strongly retained in contaminated soils.
Research has investigated its use for mobilizing metals during soil washing and enhanced phytoextraction.
Tetrasodium EDDS has also been investigated for controlling the availability of essential metals such as iron.
For example, formation of an Fe-Tetrasodium EDDS complex can maintain iron in soluble and more bioavailable forms under conditions where iron would otherwise precipitate or become less accessible.
The strong coordination properties of Tetrasodium EDDS originate from its multiple carboxylate and nitrogen donor sites.
These groups can cooperate during complex formation, producing stable metal-ligand structures rather than simple one-point interactions.
The sodium salt form is particularly suitable for aqueous formulations because conversion of the carboxylic acid groups into sodium carboxylates increases water compatibility.
This characteristic makes sodium Tetrasodium EDDS materials easier to incorporate into water-based cleaning, treatment, and formulation systems.
It is also important to distinguish Tetrasodium EDDS from trisodium Tetrasodium EDDS when specifying a chemical product.
The commercially documented [S,S]-Tetrasodium EDDS material with CAS No. 178949-82-1 is trisodium Tetrasodium EDDS, with the molecular formula C₁₀H₁₃N₂Na₃O₈, so the exact salt form should always be confirmed from the supplier specification.
Tetrasodium EDDS belongs to the family of aminopolycarboxylate chelating agents and is primarily valued for its ability to bind metal ions in aqueous and industrial systems.
Its relationship to EDTA, stereochemistry, metal-complexation capability, and the biodegradation characteristics of [S,S]-Tetrasodium EDDS make this chemical particularly relevant to modern chelation and environmentally oriented formulation technologies.
Tetrasodium EDDS can also influence metal speciation in aqueous systems by shifting metals from free ionic forms into dissolved metal–Tetrasodium EDDS complexes.
This behavior can change the apparent solubility and mobility of metals and is one of the main reasons Tetrasodium EDDS is investigated for environmental and industrial metal-management processes.
The effectiveness of Tetrasodium EDDS depends on the particular metal ion involved.
Tetrasodium EDDSs complexes with some transition metals can remain sufficiently stable to maintain the metal in solution, while complexes with alkaline-earth metals such as calcium are generally less stable than the corresponding EDTA complexes.
This difference in complex stability can provide a degree of selective metal chelation.
Because calcium and magnesium may compete differently with transition metals for the ligand, Tetrasodium EDDS can be useful in systems where selective control of particular metal ions is required.
Tetrasodium EDDS is also capable of maintaining iron in a soluble complexed form under conditions where iron might otherwise precipitate.
For example, Fe–Tetrasodium EDDS formation has been investigated as a way of improving iron bioavailability in anaerobic systems where sulfide would otherwise promote the formation of poorly soluble iron sulfide.
The environmental behavior of Tetrasodium EDDS is strongly influenced by the identity of the metal present.
Studies have shown that several metal–[S,S]-Tetrasodium EDDS complexes can undergo biodegradation, whereas complexes involving metals such as copper, nickel, cobalt, and mercury can be substantially more resistant.
This means that describing Tetrasodium EDDS simply as a readily biodegradable chelator does not fully describe its environmental behavior.
The biodegradability of the free ligand and the stability and degradation of individual metal–Tetrasodium EDDS complexes need to be considered separately.
Tetrasodium EDDS has also been investigated for heavy-metal remediation of contaminated soils.
Its ability to form soluble complexes with metals such as lead, zinc, copper, and cadmium can increase metal mobilization and facilitate their removal during soil-washing or soil-flushing processes.
In soil-remediation applications, the concentration of Tetrasodium EDDS and the contact time can significantly affect metal extraction efficiency.
The composition of the soil is also important because naturally occurring calcium, iron, aluminum, and other competing cations can consume part of the available chelating capacity.
Tetrasodium EDDS has been studied for enhanced phytoextraction, where chelation is used to increase the mobility and availability of metals for uptake by plants.
This approach has attracted attention because Tetrasodium EDDS can provide strong metal complexation while exhibiting a substantially more favorable biodegradation profile than persistent chelators such as EDTA.
Uses:
General-purpose chelating agent.
Tetrasodium EDDS is used therapeutically in treating arteriosclerosis.
Tetrasodium EDDS is used as a metal cleaner; in detergents, liquid soaps; shampoos; metal chelating agent; in textiles industry to improve dyeing, scouring, and detergent operations; antioxidant.
Tetrasodium EDDS is primarily used as a chelating agent in formulations where unwanted metal ions need to be captured and controlled.
Tetrasodium EDDS multiple carboxylate and nitrogen donor groups allow it to form complexes with transition metals and other multivalent ions.
One of the major applications of Tetrasodium EDDS is in laundry detergents and automatic dishwashing formulations.
By binding transition metals and hardness ions, Tetrasodium EDDS can reduce metal-related interference and support the overall cleaning performance of the formulation.
Tetrasodium EDDS is also used in household and industrial cleaning products where metal ions can reduce formulation stability or contribute to deposits.
Its chelating action can help control metals present on surfaces, in process water, or in cleaning solutions.
Another important application is stabilization of hydrogen peroxide and peroxygen-based bleaching systems.
Tetrasodium EDDS binds transition metals that could otherwise catalyze unwanted peroxide decomposition, helping maintain the effectiveness of the bleaching system.
Tetrasodium EDDS can similarly be used in peracetic acid-based formulations.
Its ability to control trace transition metals makes it useful when oxidative systems require improved stability during storage or processing.
Tetrasodium EDDS has applications in textile processing, particularly where metal ions can interfere with dyes, bleaching agents, or fabric appearance.
Chelation can help reduce unwanted interactions between transition metals and textile-processing chemicals, supporting more consistent processing results.
Tetrasodium EDDS is also used for dye and fabric protection in detergent and textile formulations.
Controlling trace metals can reduce metal-catalyzed discoloration and other undesirable reactions that may affect dyed materials.
Another application is in personal care and cosmetic formulations.
Tetrasodium EDDS has been investigated and commercially promoted as a biodegradable chelating agent for products where trace metal ions can affect product stability, appearance, or the performance of other ingredients.
Tetrasodium EDDS can also function as a formulation stabilizer in products containing oxidation-sensitive ingredients.
By complexing catalytic metal ions, it can help reduce metal-induced degradation pathways and support formulation stability.
Tetrasodium EDDS has applications in biocide formulations as a potentiating agent.
Chelation of metal ions can modify the chemical environment and improve the effectiveness of certain antimicrobial systems, although the specific effect depends on the formulation and active biocide involved.
Tetrasodium EDDS is also relevant to pulp and paper processing, especially peroxide bleaching.
Tetrasodium EDDS can complex transition metals that would otherwise accelerate peroxide decomposition, helping improve the stability and efficiency of oxidative bleaching processes.
Another area of application is metal cleaning and surface treatment.
Tetrasodium EDDS can help remove or mobilize transition-metal residues from surfaces, making it relevant to specialized cleaning processes and metal-contaminated equipment.
Tetrasodium EDDS has also been investigated for electroplating and electronic chemical applications.
Its ability to coordinate metal ions can be useful in processes where controlled metal speciation and solubility are important for surface treatment or plating chemistry.
In agriculture, Tetrasodium EDDS has been studied as a chelating agent for improving the availability and mobility of micronutrient metals.
Tetrasodium EDDS ability to form soluble complexes with metals such as iron can be useful in research involving nutrient delivery and plant nutrition.
Tetrasodium EDDS is particularly important in soil remediation and phytoremediation.
It can form soluble complexes with heavy metals such as lead, zinc, copper, and cadmium, increasing their mobility and facilitating extraction from contaminated soils.
Tetrasodium EDDS has also been investigated for soil washing processes.
In these applications, Tetrasodium EDDS can mobilize metals from soil particles so that the contaminated fraction can subsequently be separated from the treated soil.
Tetrasodium EDDS can be used in water and wastewater treatment research for controlling dissolved metal ions.
The formation of soluble metal–Tetrasodium EDDS complexes can alter metal speciation and can be incorporated into treatment strategies involving metal separation and recovery.
Another potential application is scale and metal-deposit control in industrial systems.
By binding selected multivalent ions, Tetrasodium EDDS can help reduce the availability of metals that participate in precipitation or deposit formation, although performance depends strongly on water chemistry and competing ions.
The combination of chelation efficiency and the relatively favorable biodegradation profile of [S,S]-Tetrasodium EDDS has encouraged its development as an alternative to more persistent chelating agents.
This makes Tetrasodium EDDS particularly relevant to environmentally oriented detergent, cleaning, agricultural, and remediation formulations.
Tetrasodium EDDS is mainly valuable for metal-ion control, cleaning, bleaching stabilization, detergent formulation, textile processing, cosmetics, agriculture, water treatment, and environmental remediation.
Its ability to coordinate transition metals while offering a more biodegradable chelation approach than conventional EDTA has made Tetrasodium EDDS an important ingredient in the development of more environmentally compatible formulations.
Tetrasodium EDDS can be used in industrial and institutional cleaning formulations where metal-ion control is needed alongside surfactants and other cleaning ingredients.
By complexing calcium, magnesium, iron, copper, and other metal ions, Tetrasodium EDDS can help reduce interference from dissolved metals and improve the consistency of cleaning systems.
Tetrasodium EDDS is also relevant to automatic dishwashing formulations, where hardness ions can contribute to deposits and reduce cleaning efficiency.
Chelation helps keep problematic metal ions under control and can support the performance of detergents in hard-water conditions.
Another application is laundry detergent formulation, where Tetrasodium EDDS can act as a biodegradable alternative to conventional persistent chelating agents.
Its ability to bind transition metals can help reduce metal-catalyzed degradation and improve the stability of detergent and bleaching systems.
Tetrasodium EDDS can also be incorporated into bleaching formulations containing oxidizing agents.
By controlling transition-metal ions that can catalyze unwanted decomposition of peroxide-based systems, Tetrasodium EDDS can help maintain the effectiveness of the bleaching chemistry.
The chemical has applications in the pulp and paper industry, particularly in bleaching processes where transition-metal sequestration is important.
Tetrasodium EDDS has evaluated Tetrasodium EDDS for controlling transition metals, retaining magnesium in pulp, and limiting undesirable interactions with calcium during different pulp-processing stages.
Tetrasodium EDDS is also investigated in textile processing because metal ions can interfere with bleaching, dyeing, and other wet-processing operations.
Metal sequestration can help control these interactions and contribute to more consistent textile treatment.
Another use is in metal and surface cleaning applications.
Tetrasodium EDDS can complex metal ions associated with deposits and contamination, making it relevant to processes involving metal surfaces, specialized cleaning systems, and surface preparation.
Tetrasodium EDDS has also been investigated for electroplating and metal-finishing processes.
Its ability to control dissolved metal ions can be useful where metal speciation, solubility, and controlled availability influence the performance of the treatment bath.
In the agricultural sector, Tetrasodium EDDS is studied as a chelating agent for managing micronutrient metals.
Complexation can increase the soluble fraction of metals such as iron and has been investigated for nutrient-delivery systems and plant-related applications.
Tetrasodium EDDS is particularly important in soil remediation and soil washing.
Its complexes with heavy metals such as lead, zinc, copper, and cadmium can increase metal mobilization and facilitate the subsequent separation of contaminated fractions from soil.
Tetrasodium EDDS is also investigated for phytoremediation and enhanced phytoextraction.
By increasing the mobility and availability of selected metals in contaminated soils, Tetrasodium EDDS can support research strategies designed to facilitate metal uptake by plants.
Tetrasodium EDDS can be relevant to water and wastewater treatment where dissolved metal ions need to be complexed before or during a separation process.
Metal–Tetrasodium EDDS complex formation can alter metal speciation and influence subsequent treatment methods such as adsorption, extraction, or other separation technologies.
Tetrasodium EDDS has also been investigated for oilfield and scale-control applications.
Chelation of calcium and other metal ions can help manage mineral deposits and metal-containing residues in systems where scale formation affects equipment or process performance.
Another potential application is in personal care and cosmetic formulations.
Tetrasodium EDDS has been developed as a biodegradable chelating and stabilizing ingredient that can control trace metal ions capable of promoting discoloration or degradation of sensitive formulation components.
Tetrasodium EDDS can also be used as a stabilizing component in formulations containing oxidation-sensitive ingredients.
Removing or complexing catalytic traces of transition metals can help reduce unwanted metal-catalyzed reactions and improve formulation stability.
The chemical has been investigated as a biocide potentiator in certain formulations.
Metal-ion sequestration can modify the chemical environment surrounding antimicrobial ingredients and potentially improve their performance, depending on the specific formulation.
Tetrasodium EDDS is also relevant to photographic and specialty chemical processing, where control of metal ions can influence chemical reactions and the stability of processing solutions.
Its application in this area is associated with the broader use of Tetrasodium EDDS as a biodegradable alternative to conventional aminopolycarboxylate chelators.
In environmental technologies, Tetrasodium EDDS can be used in research involving the mobilization and recovery of metals from contaminated materials.
Its ability to form soluble complexes makes it useful for studying controlled metal extraction from soils, wastes, and other contaminated matrices.
The relatively favorable biodegradation profile of the [S,S]-Tetrasodium EDDS stereoisomer is an important factor behind these applications.
This characteristic has encouraged the development of Tetrasodium EDDS-based formulations as alternatives to less biodegradable chelating agents in detergents, cleaning products, remediation, and industrial processing.
Safety Profile:
Tetrasodium EDDS is generally considered a low-hazard chelating agent when used under normal handling conditions.
Available regulatory information for the closely related trisodium Tetrasodium EDDS salt indicates that it does not meet the GHS classification criteria for hazardous substances in the reported notifications.
The available safety information does not indicate that Tetrasodium EDDS sodium salts are classified as acutely toxic under the reported GHS assessments.
Nevertheless, industrial and laboratory handling should still follow the applicable safety data sheet because the hazard profile can depend on the exact salt form, concentration, impurities, and commercial formulation.
Direct contact with concentrated Tetrasodium EDDS materials should be minimized even when the substance is not formally classified as a skin irritant.
Protective gloves are appropriate during repeated or prolonged handling, particularly when working with concentrated solutions or dry powders.
Eye exposure should also be avoided during handling.
Chemical dust or concentrated solutions can cause temporary discomfort or irritation, so safety glasses are recommended during weighing, transfer, and formulation operations.
As a water-soluble sodium salt, Tetrasodium EDDS can readily enter aqueous process streams when released.
Spills should therefore be contained and collected rather than washed directly into drains, particularly in industrial environments where large quantities are handled.
One important environmental consideration is that Tetrasodium EDDS is intentionally designed to bind metal ions.
Although this property is useful in detergents and remediation, chelation can increase the mobility or dissolved fraction of certain metals in soil and water.
The environmental behavior of Tetrasodium EDDS therefore depends strongly on whether the ligand is present in its free form or as a metal–Tetrasodium EDDS complex.
The [S,S] stereoisomer of Tetrasodium EDDS is relatively biodegradable, but the stability and degradation behavior of individual metal complexes can differ considerably.
This distinction is particularly important in metal-contaminated environments.
Tetrasodium EDDS can mobilize metals such as lead, copper, zinc, and cadmium, which can be beneficial during controlled remediation but may increase metal transport if released without appropriate environmental management.
The sodium salt itself is not generally associated with significant bioaccumulation concerns.
Its high water compatibility and chelating behavior instead make its environmental fate more closely related to aqueous transport, biodegradation, and interactions with metal ions.
Tetrasodium EDDS should also be handled carefully when incorporated into formulations containing heavy metals or transition metals.
Complex formation can alter the chemical availability and mobility of these metals, so environmental assessments should consider the complete formulation rather than evaluating Tetrasodium EDDS alone.
Supply Of Tetrasodium EDDS:
For further information about Tetrasodium EDDS, including available product grades, technical specifications, application suitability and supply options, please contact Ataman Kimya.
