PRODUCTS

TETRASODIUM EDTA SOLUTION

Tetrasodium EDTA solution is a versatile chelating agent derived from plant material, offering effective metal ion binding and preservation enhancement while being readily biodegradable and highly soluble across a broad pH range.
Tetrasodium EDTA solution serves as a safe and effective alternative to EDTA, providing similar chelation properties without the associated health and environmental concerns, and is used to stabilize and prolong the shelf life of various cosmetic and cleaning products.
Tetrasodium EDTA solution boosts the performance of preservatives in formulations, allowing for lower usage levels while maintaining efficacy, and is suitable for use in a wide range of personal care and cleaning applications.

CAS Number: 51981-21-6
EC Number: 257-573-7
Chemical Formula: C9H9NNa4O8
Molecular Weight: 351.14 g/mol

Synonyms: C9H13NO8Na4, L-Glutamic acid, N,N-Bis(Carboxymethyl)-, Tetrasodium Salt, L-glutamic acid N,N-diacetic acid, tetrasodium salt, GLDA-Na 4, 51981-21-6, Tetrasodium glutamate diacetate, UNII-5EHL50I4MY, 5EHL50I4MY, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, EINECS 257-573-7, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), EC 257-573-7, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, GLDA, tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, DISSOLVINE GL, CHELEST CMG-40, DTXSID2052158, UZVUJVFQFNHRSY-OUTKXMMCSA-J, MFCD01862262, B2135, Tetrasodium glutamate diacetate [INCI], GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, Q25393000, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, N,N-bis-(Carboxymethyl)-L-glutamic Acid Tetrasodiumn Salt (40% in water), tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate), Tetrasodium glutamate diacetate, 51981-21-6, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, UNII-5EHL50I4MY, 5EHL50I4MY, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, EINECS 257-573-7, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), EC 257-573-7, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, GLDA, tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, N,N-bis-(Carboxymethyl)-L-glutamic Acid Tetrasodiumn Salt (40% in water), DISSOLVINE GL, CHELEST CMG-40, DTXSID2052158, MFCD01862262, B2135, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, Q25393000, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, TETRASODIUM (2S)-2-[BIS(CARBOXYLATOMETHYL)AMINO]PENTANEDIOATE, tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate), C9H13NO8Na4, L-Glutamic acid, N,N-Bis(Carboxymethyl)-, Tetrasodium Salt, CHELEST CMG-40, DISSOLVINE GL, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, SODIUM SALT (1:4), L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, Tetrasodium glutamate diacetate, TETRASODIUM N,N-BIS(CARBOXYMETHYL)-L-GLUTAMATE, L-Glutamic Acid,N-N Diacetic acid tetra sodium salt; EcoChelate GLDA

Tetrasodium EDTA solution is a 'chelating agent'.
Tetrasodium EDTA solution boosts performance of preservatives improving shelf life.

Tetrasodium EDTA solution stabilizes the pH value and is effective in wide pH range.
Tetrasodium EDTA solution is a versatile, clear, liquid chelating agent and preservative booster.

Derived from plant material, Tetrasodium EDTA solution is readily biodegradable and highly soluble across a broad pH range.
Tetrasodium EDTA solution effectively fulfills the same purpose in formulations as EDTA but without the associated health and environmental concerns.

Tetrasodium EDTA solution acts as a safe alternative, offering effective chelation and preservation properties without compromising on performance.
Tetrasodium EDTA solution has a molecular weight of 351.13 and its molecular formula is C9H9NNa4O8.
Tetrasodium EDTA solution works to create bonds with unchecked ions that can alter a formula's appearance, such as preserving soap and keeping it from going bad.

Tetrasodium EDTA solution is a high purity, versatile and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Tetrasodium EDTA solution is a excellent chelating effectiveness controlling metal catalyzed decomposition.

Tetrasodium EDTA solution reduces water hardness and prevents precipitation.
Tetrasodium EDTA solution boosts performance of preservatives improving shelf life.

Tetrasodium EDTA solution stabilizes the pH value and is effective in wide pH range.
Tetrasodium EDTA solution does not sensitize human skin.

Completely biodegradable as compared to phosphates and phosphonates.
Tetrasodium EDTA solution is effective alternative to EDTA.

Tetrasodium EDTA solution is what's known as a 'chelating agent', an ingredient that inactivates metallic ions (charged particles) in product formulations.
Free roaming iron and copper ions in formulations can lead to rapid oxidation, meaning they will spoil quickly.

Tetrasodium EDTA solution is a 'chelating agent'.
Tetrasodium EDTA solution is a multi-purpose chelating agent and preservative booster.

Tetrasodium EDTA solution serves the same function in formulations as EDTA.
Tetrasodium EDTA solution is made from plant material, readily biodegradable, with high solubility over a wide pH range.

Tetrasodium EDTA solution is a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium EDTA solution is made from plant material, readily biodegradable, with high solubility over a wide pH range.

Tetrasodium EDTA solution serves the same function in formulations as EDTA, without the health and environmental concerns.
Tetrasodium EDTA solution is a safe synthetic chelating agent with natural origins.

Tetrasodium EDTA solution is a nitrilotriacetic acid (NTA)-free and EDTA free chelating agent.
Tetrasodium EDTA solution is non-toxic produced from a naturally occurring amino acid.

Tetrasodium EDTA solution offers enhanced preservative boosting power.
Tetrasodium EDTA solution is recommended for wash-off formulations, wipes, shaving products, fragrances, toiletries, makeup, skin-, sun, baby & oral care products.

This synthetic, Tetrasodium EDTA solution, yet non-toxic molecule is a chelating agent.
This means that Tetrasodium EDTA solution creates bonds with certain ions that, if left unchecked, could alter the formula's appearance and even the safety of the product.

In soap, Tetrasodium EDTA solution prevents rancidity.
Tetrasodium EDTA solution is, therefore, a kind of preservative.

Tetrasodium EDTA solution is high purity, versatile and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Tetrasodium EDTA solution is also known as GLDA chelate.

Tetrasodium EDTA solution is a chemical compound that is commonly used in cleaning products.
Tetrasodium EDTA solution is a white powder that is soluble in water, and Tetrasodium EDTA solution has a number of benefits when used as a cleaning agent.

Tetrasodium EDTA solution is effective at removing dirt, grease, and grime from surfaces, and Tetrasodium EDTA solution can also help to prevent the growth of mold and mildew.
In addition, Tetrasodium EDTA solution is non-toxic and biodegradable, making it safe for use around children and pets.

Tetrasodium EDTA solution is an important ingredient in many popular cleaning products, and Tetrasodium EDTA solution can be an effective way to keep your home clean and healthy.
The L form of Tetrasodium EDTA solution, or GLDA, is based on renewable materials (fermented sugar), functions across a wider pH range, matches or exceeds EDTA in controlling soap scum and is readily biodegradeable.

Tetrasodium EDTA solution is also being researched for use as a micronutrient.
Tetrasodium EDTA solution is free from genetically modified raw materials and is not irritating to skin or eyes.
Tetrasodium EDTA solution is a greener alternative, as it is predominately made from sugar waste material.

The environmental impact (according to ISO 14040) of all strong complexing builders was measured and Tetrasodium EDTA solution has the smallest ecological footprint.
Tetrasodium EDTA solution is the substituted amine salt that conforms to the formula: C9H9NO3 • 4Na

Uses of Tetrasodium EDTA Solution:
Typical use level of Tetrasodium EDTA solution is 0.1-0.5%.
Add Tetrasodium EDTA solution at the end of formulation process or to water phase of emulsions.
Tetrasodium EDTA solution is used for external use only.

Tetrasodium EDTA solution is used in amounts up to 1% to boost the effectiveness of preservatives, allowing for the use of lower amounts than is typical without compromising effectiveness.
Tetrasodium EDTA solution is readily biodegradable with a high level of solubility over a wide pH range, thus a greener alternative to many other chelates and phosphates.

Due to the strong chelating ability of calcium and transition metal ions, Tetrasodium EDTA solution can prolong the shelf life of many cosmetic products, as well as stabilize and prevent from discoloration.
Tetrasodium EDTA solution is used all kinds of cosmetic products like creams, lotions, shampoos, conditioners, makeup products, sunscreen products, hair colorings, powders, personal care wipes.

Tetrasodium EDTA solution is a chelating agent and preservative enhancer.
Tetrasodium EDTA solution is used in cosmetics mainly because of its ability to boost the effectiveness of other preservatives.
Tetrasodium EDTA solution is also used to stabilise the ingredients of cosmetic formulations, preventing the natural discolouration of shampoos and gels.

Tetrasodium EDTA solution usually appears as an odorless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium EDTA solution is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).

Tetrasodium EDTA solution usually appears as an odourless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Using a chelating agent helps to slow this process, allowing for the creation of products with improved stability and appearance.

This also improves the effectiveness of preservative ingredients, allowing us to use a lower percentage of these, for safer shelf-stable products.
Tetrasodium EDTA solution is a chelating agent.

Tetrasodium EDTA solution helps maintain pH and removes heavy metal ions from the formulation by binding with them.
Tetrasodium EDTA solution helps prevent the formula from oxidizing or otherwise spoiling.

Tetrasodium EDTA solution is a safe synthetic chelating agent with natural origins.
Tetrasodium EDTA solution is used in amounts up to 1% to boost the effectiveness of preservatives, allowing for the use of lower amounts than is typical without compromising effectiveness.

Tetrasodium EDTA solution has many uses from food to personal care products.
Tetrasodium EDTA solution is used shampoos Sequestering agent in shampoos & cleaners to improve stability.

Tetrasodium EDTA solution is used to prevent metal ion impurities from modifying colors of dyed products.
Tetrasodium EDTA solution is used as preservative in some foods to prevent catalytic oxidative discoloration.

Tetrasodium EDTA solution is used to remove water hardness in laundry applications.
Tetrasodium EDTA solution is used to prevent scale formation in boilers due to water hardness.

Tetrasodium EDTA solution is used in complexometric titrations and analysis of water hardness.
Tetrasodium EDTA solution is a naturally and sustainably produced sequestrant derived from the Amino Acid Glutamic acid.
Tetrasodium EDTA solution can be used to replace EDTA acid and EDTA salts such as Tetrasodium EDTA in a 1:1 ratio.

Tetrasodium EDTA solution is an alkaline sequestering agent it binds up and makes inert impurities such as metal ions of iron, magnesium and calcium, and prevents them from interacting with other ingredients.
Tetrasodium EDTA solution is a chelating agent created from natural, biodegradable and renewable raw materials.

Tetrasodium EDTA solution is suitable to be used in personal care and cosmetics
Stable over a wide pH range and highly soluble, Tetrasodium EDTA solution works to create bonds with unchecked ions that can alter a formula’s appearance.

For example, this can preserve soap and prevent Tetrasodium EDTA solution from going bad.
Tetrasodium EDTA solution can also function as a preservative enhancer.

Tetrasodium EDTA solution inactivates metallic ions (charged particles) in product formulations, hence acting as is a chelating agent.

Free roaming iron and copper ions in formulations can lead to rapid oxidation.
Using a chelating agent, Tetrasodium EDTA solution, helps to slow this process, allowing for the creation of products with improved stability and appearance.

This also improves the effectiveness of preservative ingredients, allowing us to use a lower percentage of these, for safer shelf-stable products.
Tetrasodium EDTA solution is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, cleansing wipes, bar soap, and other cleaning products.

Cleaning:
Tetrasodium EDTA solution is a multi-functional ingredient that can be used in a variety of cleaning products.
Tetrasodium EDTA solution is an effective degreaser and can be used to remove oils and greases from surfaces.

Tetrasodium EDTA solution is also a powerful dispersant, which means it can be used to break up stubborn dirt and grime.
In addition, Tetrasodium EDTA solution is a great sanitizer and can help to kill bacteria and viruses.
As a result, Tetrasodium EDTA solution is an ideal ingredient for use in a wide range of cleaning products.

Personal Care:
Tetrasodium EDTA solution is a multi-functional ingredient used in personal care products.
Tetrasodium EDTA solution has excellent solubility in water and good binding properties.
Tetrasodium EDTA solution can be used as a surfactant, emulsifier, conditioner, or suspender.

Tetrasodium EDTA solution is also an effective chelating agent that helps to improve the performance of other ingredients in a formulation.
Tetrasodium EDTA solution is compatible with most cosmetic bases and can be used in a wide variety of products, including shampoos, conditioners, body washes, and lotions.

When used at the recommended concentration, Tetrasodium EDTA solution is safe and effective for both leave-on and rinse-off products.
Tetrasodium EDTA solution is an excellent choice for personal care formulations that require high performance and reliability.

Features of Tetrasodium EDTA Solution:

High solubility under wide pH:
Tetrasodium EDTA solution has good solubility in strong acid to high alkali systems, and has better advantages for formulating high active ingredients and low water content formulation systems.

Good stability under high temperature:
By thermogravimetric analysis, Tetrasodium EDTA solution is tested at 170°C for 6 hours or at 150°C for a week.
Tetrasodium EDTA solution has no decomposition and is extremely stable.
Compared with other chelating agent products at 100°C, Tetrasodium EDTA solution has the best performance.

Strong chelating ability:
Tetrasodium EDTA solution has a good effect on all kinds of difficult-to-clean calcium scales or difficult-to-clean equipment.

Has the effect of antiseptic and synergistic:
Because Tetrasodium EDTA solution has natural amino acid components, Tetrasodium EDTA solution has a stronger binding ability with animal cell walls, and thus play a role in antiseptic and synergistic.
After experiments, we found that Tetrasodium EDTA solution has obvious antiseptic and sterilization synergies in many fungicides, which can save 20%-80% of the usage.

Benefits of Tetrasodium EDTA Solution:
Tetrasodium EDTA solution works as a stabilizer in cosmetic formulations to preventing the natural discoloration of shampoos and gels.
Tetrasodium EDTA solution is used to enhance and preservative the formulation’s ingredients and also acts as a heavy metal chelating agent.

Other Benefits:
Excellent chelating effectiveness controlling metal catalyzed decomposition
Reduces water hardness and prevents precipitations
Boosts performance of preservatives improving shelf life
Stabilizes the pH value and is effective in wide pH range
Does not sensitize human skin
Completely biodegradable as compared to phosphates and phosphonates
Effective alternative to EDTA

Functions of Tetrasodium EDTA Solution:

Chelating:
Tetrasodium EDTA solution reacts and forms complexes with metal ions that could affect the stability and / or appearance of cosmetic products
Tetrasodium EDTA solution binds metal ions which could negatively affect the stability and / or appearance of cosmetics

Production of Tetrasodium EDTA Solution:

The production of Tetrasodium EDTA solution involves several chemical steps:

Glutamic Acid:
Glutamic acid, an amino acid derived from vegetable sources like sugar beets or wheat, serves as the starting material.

Esterification:
Tetrasodium EDTA solution undergoes esterification to produce a compound known as glutamic acid diethyl ester.

Hydrolysis:
Hydrolysis of the ester yields the final product, Glutamic Acid Diacetic Acid or GLDA.
The resulting Tetrasodium EDTA solution is then purified and formulated into the desired products or applications.

In conclusion, Tetrasodium EDTA solution is a versatile chelating agent used in various industries due to its ability to bind to metal ions and prevent issues such as scaling and spoilage.
Tetrasodium EDTA solution's biodegradability, compatibility, and environmentally friendly nature make Tetrasodium EDTA solution a valuable ingredient in cleaning products, personal care items, and the food and beverage industry.
Understanding Tetrasodium EDTA solution's benefits and production process underscores its significance in modern manufacturing and product development.

Origin of Tetrasodium EDTA Solution:
Tetrasodium EDTA solution is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).

Alternatives of Tetrasodium EDTA Solution:
Trisodium Ethylenediamine Disuccinate
EDTA

Safety Profile of Tetrasodium EDTA Solution:
The safety of Tetrasodium EDTA solution was assessed by the Expert Panel for Cosmetic Ingredient Safety (formerly called the Cosmetic Ingredient Review Expert Panel) in 2021.
The Expert Panel concluded that Tetrasodium EDTA solution was safe as used in the present practices of use and concentration in cosmetics and personal care products.
The Expert Panel noted Tetrasodium EDTA solution is slowly absorbed through the gastrointestinal tract and skin absorption is likely to be even slower.

Handling And Storage of Tetrasodium EDTA Solution:

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.

Stability And Reactivity of Tetrasodium EDTA Solution:

Reactivity:
No data available

Chemical stability:
Stable under recommended storage conditions.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
No data available

First Aid Measures of Tetrasodium EDTA Solution:

If inhaled:
If breathed in, move person into fresh air.

In case of skin contact:
Wash off with soap and plenty of water.

In case of eye contact:
Flush eyes with water as a precaution.

If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.

Indication of any immediate medical attention and special treatment needed:
No data available

Fire Fighting Measures of Tetrasodium EDTA Solution:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Further information:
No data available

Accidental Release Measures of Tetrasodium EDTA Solution:

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.

Exposure Controls/Personal Protection of Tetrasodium EDTA Solution:

Personal protective equipment:

Eye/face protection:
Use equipment for eye protection.

Skin protection:
Handle with gloves.
Wash and dry hands.

Body Protection:
Impervious clothing.

Respiratory protection:
Respiratory protection not required.

Control of environmental exposure:
Do not let product enter drains.

Identifiers of Tetrasodium EDTA Solution:
CAS Number: 51981-21-6
Chemical Formula: C9H9NNa4O8
Molecular Weight: 351.14 g/mol
EINECS Number: 257-573-7
UNII: QF6M1M3U5H
InChI Key: XZHKHCHEVDMAES-UHFFFAOYSA-J

CAS Number: 51981-21-6
EC Number: 257-573-7
Chem/IUPAC Name: Tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioatee
Molecular formula: C9H9NO8Na4

Properties of Tetrasodium EDTA Solution:
Appearance: Light yellow viscous liquid
Content /%: ≥47
pH value: ≥8.5
Density(20℃) g/cm3: ≥1.20
Boiling Point: 105-110°C
Specific Gravity: 1.15-1.45
pH: 11-12 (in 1% water)
Solubility: Completely miscible in water
Slightly soluble in methanol/ethanol
Viscosity: 75-275 mPa.s @ 25°C

Molecular Weight: 351.13 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 5
Exact Mass: 350.99189337 g/mol
Monoisotopic Mass: 350.99189337 g/mol
Topological Polar Surface Area: 164Å²
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes

Boiling Point: 105-110°C
Specific Gravity: 1.15-1.45
pH: 11-12 (in 1% water)
Solubility: Completely miscible in water,
Slightly soluble in methanol/ethanol
Viscosity: 75-275 mPa.s @ 25°C
Molecular Weight: 351.13 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 5
Exact Mass: 350.99189337 g/mol
Monoisotopic Mass: 350.99189337 g/mol
Topological Polar Surface Area: 164Å²
Heavy Atom Count: 22
Complexity: 314