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Tetrasodium Glutamate Diacetate (GLDA) usually appears as an odorless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium Glutamate Diacetate (GLDA) has a molecular weight of 351.13 and its molecular formula is C9H9NNa4O8.
Tetrasodium Glutamate Diacetate (GLDA) is a powerful chelating agent made from natural, biodegradable, renewable raw materials and also functions as an eective preservative booster.
CAS Number: 51981-21-6
Molecular Formula: C9H14NNaO8
Molecular Weight: 287.2
EINECS Number: 257-573-7
Synonyms: Tetrasodium glutamate diacetate, 51981-21-6, UNII-5EHL50I4MY, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, 5EHL50I4MY, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, EINECS 257-573-7, DISSOLVINE GL, CHELEST CMG-40, EC 257-573-7, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), DTXSID2052158, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, GLDA, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, tetrasodium,(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), N,N-bis-(Carboxymethyl)-L-glutamic Acid Tetrasodiumn Salt (40% in water), Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, MFCD01862262, DTXCID7030727, B2135, TETRASODIUM GLUTAMATE DIACETATE [INCI], Q25393000, TETRASODIUM (2S)-2-[BIS(CARBOXYLATOMETHYL)AMINO]PENTANEDIOATE, tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate)tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate,TETRASODIUM GLUTAMATE DIACETATE,TETRASODIUM N,N-BIS(CARBOXYMETHYL)-L-GLUTAMATE,N,N-BIS(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUM SALT,N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT,Glutamic acid diacetic acid, tetrasodium salt,N,N-Bis(carboxymethyl)glutamate, tetrasodium salt,L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, Tetrasodium Glutamate Diacetate is a 'chelating agent'.
Tetrasodium Glutamate Diacetate (GLDA) complexes hard water ions eectively whilst retaining its high chelating value at elevated temperatures compared to other chelating agents.
Tetrasodium Glutamate Diacetate (GLDA) can be used as a more sustainable alternative to phosphonates and commonly used chelating agents (NTA and EDTA) in a wide number of applications.
Tetrasodium Glutamate Diacetate (GLDA) inactivates metallic ions (charged particles) in product formulations, hence acting as is a chelating agent.
Free roaming iron and copper ions in formulations can lead to rapid oxidation.
Using a chelating agent helps to slow this process, allowing for the creation of products with improved stability and appearance.
This also improves the effectiveness of preservative ingredients, allowing us to use a lower percentage of these, for safer shelf-stable products.
Tetrasodium Glutamate Diacetate (GLDA) is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, cleansing wipes, bar soap, and other cleaning products.
Tetrasodium Glutamate Diacetate (GLDA) is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).
Tetrasodium Glutamate Diacetate (GLDA) is a biodegradable chelating agent derived from natural raw materials.
It belongs to the class of aminopolycarboxylates and is used in a variety of applications, primarily for its ability to bind metal ions effectively.
Tetrasodium Glutamate Diacetate (GLDA) with a concentration about 47%, it is aminopolycarboxylate-based chelating agent based on the food-approved natural amino acid salt, monosodium L-glutamate, which is produced by biochemical conversion of vegetable material (such as sugar beet waste).
Tetrasodium Glutamate Diacetate (GLDA) is readily biodegradable, with a high solubility over a wide pH range.
Tetrasodium Glutamate Diacetate (GLDA) does not sensitize human skin, demonstrates enhanced biocidal boosting power and improved biodegradability properties.
Compared to phosphates and phosphonates, it is a far more eective chelating agent.
Tetrasodium Glutamate Diacetate (GLDA) is a high-purity versatile and readily biodegradable chelate based on amino acid chemistry.
This natural and renewable product is recommended for use in disinfectants, hard surface cleaners, laundry detergents, dishwashing detergents, shampoos and body washes.
Tetrasodium Glutamate Diacetate (GLDA) usually appears as an odourless white powder that is soluble in water Tetrasodium glutamate diacetate GLDA is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium Glutamate Diacetate (GLDA) is a vegetable-based chelating agent.
Tetrasodium Glutamate Diacetate (GLDA) is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, and other products.
Tetrasodium Glutamate Diacetate (GLDA) can be found in detergents, cleansing wipes, bar soap, and other cleaning products.
Tetrasodium Glutamate Diacetate (GLDA) acts as a stabilizer in cosmetic formulations to prevent natural discoloration in shampoos and gels.
It is a substance consisting of molecules possessing two or more atoms that can bind to the same metal atom to form stable complexes.
In cosmetics they are often used to reduce or prevent reactions catalyzed by trace or impurity metals in formulations.
They also enhance the effect of the preservative in some cases and generally give stability to the formulation.
Tetrasodium Glutamate Diacetate (GLDA) is a high-purity, versatile and readily biodegradable chelator based on L-glutamic acid, a natural and renewable raw material.
Tetrasodium Glutamate Diacetate (GLDA) is in liquid form with a transparent coloration.
It is bio-compatible and bio-degradable.
Tetrasodium Glutamate Diacetate (GLDA) is used to enhance and preserve formulation ingredients and also acts as a heavy metal chelator.
Tetrasodium Glutamate Diacetate (GLDA) is a rinsing aid.
Tetrasodium Glutamate Diacetate (GLDA) is used in sunscreens, facial cleansers, shampoos, makeup, lotions.
Tetrasodium Glutamate Diacetate (GLDA) is a safe synthetic chelating agent with natural origins.
Tetrasodium Glutamate Diacetate (GLDA) also helps to maintain clarity, protect fragrance compounds and prevent rancidity.
Tetrasodium Glutamate Diacetate (GLDA) is used in bath soaps, detergents and non-spray deodorant product.
Tetrasodium Glutamate Diacetate (GLDA) is a multi-purpose, clear, liquid.
Tetrasodium glutamate diacetate GLDA is chelating agent.
Tetrasodium glutamate diacetate GLDA is preservative booster.
Tetrasodium glutamate diacetate GLDA is made from plant material.
Tetrasodium Glutamate Diacetate (GLDA) is a plant-based chelating agent.
Tetrasodium Glutamate Diacetate (GLDA) is the counterpart of EDTA but unlike EDTA, it is extracted from the seed of an Indian plant, Cassia Angustifolia.
Tetrasodium Glutamate Diacetate (GLDA) is native to the Arabias and Somalia and is cultivated in many locations in India.
Tetrasodium Glutamate Diacetate (GLDA) is a substance consisting of molecules possessing two or more atoms that can bind to the same metal atom to form stable complexes.
In cosmetics they are often used to reduce or prevent reactions catalyzed by trace or impurity metals in formulations.
They also enhance the eect of the preservative in some cases and generally give stability to the formulation.
Tetrasodium Glutamate Diacetate (GLDA) is a high-purity, versatile and readily biodegradable chelator based on L-glutamic acid, a natural and renewable raw material.
Tetrasodium Glutamate Diacetate (GLDA) is in liquid form with a transparent coloration.
Tetrasodium Glutamate Diacetate (GLDA) is bio-compatible and bio-degradable.
Since Tetrasodium Glutamate Diacetate (GLDA) is not easily absorbed by the skin, it does not irritate or sensitize it.
The use of Tetrasodium Glutamate Diacetate (GLDA) is approved in the formulation of Bio Natural cosmetics.
Tetrasodium Glutamate Diacetate (GLDA) is a high purity, versatile and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Excellent chelating effectiveness controlling metal catalyzed decomposition.
Reduces water hardness and prevents precipitations.
Boosts performance of preservatives improving shelf life.
Tetrasodium Glutamate Diacetate (GLDA) stabilizes the pH value and is effective in wide pH range.
Tetrasodium Glutamate Diacetate (GLDA) completely biodegradable as compared to phosphates and phosphonates.
Tetrasodium Glutamate Diacetate (GLDA) is an excellent chelator, capable of binding with metal ions like calcium, magnesium, iron, and others.
Readily biodegradable and considered environmentally friendly compared to traditional chelating agents like EDTA or NTA.
Effective over a wide pH range, making it suitable for both acidic and alkaline conditions.
Density: 1.466[at 20℃]
vapor pressure: 80Pa at 20℃
storage temp.: Refrigerator
solubility: Water
form: Colourless Solution
color: Light orange to Yellow to Green
Water Solubility: 650g/L at 21℃
Stability: Hygroscopic
InChI InChI=1/C9H13NO8.Na.H/c11-6(12)2-1-5(9(17)18)10(3-7(13)14)4-8(15)16,,/h5H,1-4H2,(H,11,12)(H,13,14)(H,15,16)(H,17,18),,/t5-,,/s3
InChIKey: VWDYINKBFDHFPJ-WHWWGIJDNA-N
SMILES: N(CC(=O)O)(CC(=O)O)[C@H](C(=O)O)CCC(=O)O.[NaH] |&1:9,r|
Tetrasodium Glutamate Diacetate (GLDA) Connect Chemicals is a nitrilotriacetic acid (NTA)-free and EDTA free chelating agent.
It is non-toxic produced from a naturally occurring amino acid.
It offers enhanced preservative boosting power.
Tetrasodium Glutamate Diacetate (GLDA) is recommended for wash-off formulations, wipes, shaving products, fragrances, toiletries, makeup, skin-, sun, baby & oral care products.
Tetrasodium Glutamate Diacetate (GLDA) is readily biodegradable with a high level of solubility over a wide pH range, thus a greener alternative to many other chelates and phosphates.
Due to the strong chelating ability of calcium and transition metal ions, it can prolong the shelf life of many cosmetic products, as well as stabilize and prevent from discoloration.
Tetrasodium Glutamate Diacetate (GLDA) is a compound used in the production of detergents, cleaners and textile auxiliaries.
In addition, Tetrasodium Glutamate Diacetate (GLDA) also includes many applications in oil eld water treatment, pulp and paper auxiliaries, etc.
Tetrasodium Glutamate Diacetate (GLDA) is a derivative of glutamate.
Tetrasodium Glutamate Diacetate (GLDA) can be obtained by soaking dried medicinal herbs in water for four weeks before drying them.
Tetrasodium Glutamate Diacetate (GLDA) is the main active ingredient in most commercial cleaners and cleaning products.
Tetrasodium Glutamate Diacetate (GLDA) is also used to make certain types of medicines, such as antibiotics and anti-inammatory drugs.
Tetrasodium Glutamate Diacetate (GLDA) can be easily found in many of the products we use, such as detergents, cleaners and textile auxiliaries.
Tetrasodium Glutamate Diacetate (GLDA) can be used to replace EDTA in a 1:1 ratio in many applications and products.
Tetrasodium Glutamate Diacetate (GLDA) also does not sensitise human skin and provides enhanced biocidal/preservative boosting power when compared to commonly used boosters such as EDTA and NTA.
Tetrasodium Glutamate Diacetate (GLDA) can be used in many applications such as industrial and household cleaners for improving the detergency.
Tetrasodium Glutamate Diacetate (GLDA) when added to a formulation can help stabilise the product and prevent discoloration.
In larger quantities it will enhance the cleaning ability and prevent deactivation of active ingredients during use.
Tetrasodium Glutamate Diacetate (GLDA) also reduces the eect of Calcium and Magnesium ions resulting in better surfactant performance.
Tetrasodium glutamate diacetate GLDA is suitable to be used in personal care and cosmetics products, due to the strong chelating
ability of calcium and transition metal ions prolonging the shelf life of many products.
Glutamic acid, an amino acid derived from vegetable sources like sugar beets or wheat, serves as the starting material.
Glutamic acid undergoes esterification to produce a compound known as glutamic acid diethyl ester.
Hydrolysis of the ester yields the final product, Glutamic Acid Diacetic Acid or GLDA.
Tetrasodium Glutamate Diacetate (GLDA) is a high-purity versatile and readily biodegradable chelate based on amino acid chemistry.
This natural and renewable product is recommended for use in disinfectants, hard surface cleaners, laundry detergents, dishwashing detergents, shampoos and body washes.
Tetrasodium Glutamate Diacetate (GLDA) is a plant-based chelating agent.
It is the counterpart of EDTA but unlike EDTA, it is extracted from the seed of an Indian plant, Cassia Angustifolia.
Cassia Angustifolia (angustifolia = narrow leaf) is native to the Arabias and Somalia and is cultivated in many locations in India.
Tetrasodium Glutamate Diacetate (GLDA), or Tetrasodium glutamate diacetate, is a biodegradable chelating agent used in various industries for its exceptional ability to bind to metal ions.
This versatile compound is a derivative of glutamic acid, an amino acid found in living organisms.
Tetrasodium Glutamate Diacetate (GLDA) is highly water-soluble and environmentally friendly, making it a preferred choice for applications where chelation and metal ion control are essential.
Tetrasodium Glutamate Diacetate (GLDA) is biodegradable, which means it breaks down naturally in the environment, posing minimal harm to ecosystems.
It has a high affinity for metal ions, making it effective in preventing metal-related issues such as scale formation and discoloration.
Its biodegradability and low toxicity make it an environmentally friendly option for various applications.
Tetrasodium Glutamate Diacetate (GLDA) is compatible with a wide range of other ingredients, making it a versatile choice for formulation in various products.
Tetrasodium Glutamate Diacetate (GLDA) is more environmentally friendly due to its high biodegradability, making it a preferred choice for green formulations.
It has low toxicity and is safe for use in various applications.
Tetrasodium Glutamate Diacetate (GLDA) is approved for use in various industries, and its safety profile is well-established.
For example, in the cosmetics industry, it is often listed under its INCI name, Tetrasodium Glutamate Diacetate.
Uses Of Tetrasodium Glutamate Diacetate (GLDA):
Tetrasodium Glutamate Diacetate (GLDA) is used in the following products: washing & cleaning products, polishes and waxes, air care products and biocides (e.g. disinfectants, pest control products).
Other release to the environment of Tetrasodium Glutamate Diacetate (GLDA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Release to the environment of Tetrasodium Glutamate Diacetate (GLDA) can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).
Other release to the environment of Tetrasodium Glutamate Diacetate (GLDA) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Tetrasodium Glutamate Diacetate (GLDA) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).
Tetrasodium Glutamate Diacetate (GLDA) is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Tetrasodium Glutamate Diacetate (GLDA) can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid, of substances in closed systems with minimal release and in processing aids at industrial sites.
Tetrasodium Glutamate Diacetate (GLDA) is a key ingredient in many household and industrial cleaning products.
It helps remove mineral deposits and prevents scale buildup in dishwashers, washing machines, and industrial equipment.
In personal care items such as shampoos, soaps, and shower gels, Tetrasodium Glutamate Diacetate (GLDA) is used to improve the stability and effectiveness of these products.
Tetrasodium Glutamate Diacetate (GLDA) is utilized as a food additive in the food industry.
It helps preserve the color, flavor, and quality of various processed foods by chelating metal ions that can cause spoilage or degradation.
Tetrasodium Glutamate Diacetate (GLDA) can be used in agriculture as a chelating agent for soil amendments, ensuring that essential nutrients are available to plants while minimizing nutrient loss due to soil pH or metal ion interactions.
Used in household and industrial cleaning products, including laundry detergents, dishwashing liquids, and surface cleaners.
Improves cleaning efficiency by softening water and preventing scale formation.
Found in cosmetic formulations such as shampoos, conditioners, and skin-care products, where it enhances the stability and effectiveness of the formulations.
Tetrasodium Glutamate Diacetate (GLDA) plays a crucial role in enhancing the performance of cleaning products by chelating metal ions present in hard water, which helps to improve the cleaning efficiency of surfactants by preventing mineral deposits and ensuring that detergents and cleaning agents work effectively even in water with high mineral content.
In household products, such as dishwashing liquids and laundry detergents, Tetrasodium Glutamate Diacetate (GLDA) helps in maintaining fabric quality and the luster of dishes, while in industrial cleaning, it is used to remove scale, rust, and heavy metal residues from equipment and surfaces without causing significant damage to the materials being cleaned.
Used in fertilizers to enhance nutrient availability in the soil.
In the personal care industry, GLDA is widely used in shampoos, conditioners, and skincare products where it acts as a chelating agent to bind trace metal ions that can cause undesirable changes, such as discoloration or reduced efficacy of the formulations, ensuring that the final products remain stable and effective over their shelf life.
Additionally, its ability to prevent mineral buildup makes it particularly valuable in hair care products, where it enhances the performance of active ingredients and helps maintain the natural shine and smoothness of hair.
Tetrasodium Glutamate Diacetate (GLDA) is commonly used in cleaning products to enhance their performance by softening water, removing scale, and improving the action of surfactants.
Found in dishwashing liquids, laundry detergents, and surface cleaners.
Tetrasodium Glutamate Diacetate (GLDA) is used for descaling, removing rust, and cleaning metal surfaces in industrial facilities.
Tetrasodium Glutamate Diacetate (GLDA) included in car wash and detailing products.
Tetrasodium Glutamate Diacetate (GLDA) improves the stability and performance of personal care formulations by chelating metal ions.
Prevents mineral buildup in hair care products.
Tetrasodium Glutamate Diacetate (GLDA) helps maintain product stability and prevents discoloration caused by trace metals.
Tetrasodium Glutamate Diacetate (GLDA) is used in bath salts and body washes for enhanced water-softening properties.
Tetrasodium Glutamate Diacetate (GLDA) is used as a sequestrant and stabilizer in food processing.
Binds metal ions to prevent discoloration, oxidation, and off-flavors in food.
Enhances shelf life by inhibiting microbial growth.
Prevents scale formation in production equipment.
Tetrasodium Glutamate Diacetate (GLDA) is effective in water treatment processes for preventing scale and corrosion.
As a food-grade chelating agent, Tetrasodium Glutamate Diacetate (GLDA) is used to stabilize food products by binding metal ions that can accelerate spoilage, oxidation, or the development of off-flavors, ensuring that the taste, appearance, and nutritional quality of the food remain consistent.
In beverage manufacturing, Tetrasodium Glutamate Diacetate (GLDA) helps maintain the clarity and stability of liquids by preventing the formation of cloudy precipitates caused by metal ions, and it is also used to clean production equipment by removing scale and biofilms, which could otherwise compromise the quality and safety of the beverages.
Tetrasodium Glutamate Diacetate (GLDA) plays an important role in the pulp and paper industry by improving the bleaching process, where it chelates metal ions that catalyze the degradation of cellulose fibers, thereby enhancing the brightness and durability of paper products while reducing the need for harsh chemicals.
Additionally, it helps in maintaining the cleanliness and efficiency of processing equipment by preventing scale and deposit formation, which can lead to costly downtimes and repairs.
Tetrasodium Glutamate Diacetate (GLDA) is increasingly used in environmental cleanup operations due to its ability to chelate and immobilize toxic heavy metals like lead, cadmium, and mercury, making them easier to remove from contaminated soil and water.
Its high biodegradability and low toxicity make it a sustainable choice for remediation projects, particularly in sensitive ecosystems, where traditional chemical agents might pose additional risks to the environment.
Tetrasodium Glutamate Diacetate (GLDA) improves nutrient availability in fertilizers and soil treatments.
Chelates essential micronutrients (e.g., iron, zinc, and manganese) to ensure better plant absorption.
Tetrasodium Glutamate Diacetate (GLDA) enhances soil structure by reducing the impact of hard water.
Used in cleaning and degreasing metal surfaces, including automotive and aerospace components.
Helps in enhanced oil recovery (EOR) and cleaning equipment in oil and gas industries.
Prevents scaling and discoloration during dyeing processes.
Tetrasodium Glutamate Diacetate (GLDA) is favored for eco-friendly formulations due to its high biodegradability and low toxicity.
Tetrasodium Glutamate Diacetate (GLDA) is used in products aimed at reducing environmental impact.
In agriculture, Tetrasodium Glutamate Diacetate (GLDA) enhances the bioavailability of essential micronutrients like iron, zinc, and manganese by chelating these elements, ensuring they remain soluble and easily absorbable by plants, which improves crop yield and quality.
Furthermore, its ability to work effectively across a wide pH range makes it suitable for use in both alkaline and acidic soils, where it helps to correct nutrient deficiencies and promotes healthy plant growth without causing adverse environmental effects.
In industrial processes, Tetrasodium Glutamate Diacetate (GLDA) is utilized as a safer and more sustainable alternative to traditional chelating agents like EDTA, particularly in metal cleaning and descaling operations, where it efficiently removes heavy metal deposits, rust, and limescale from machinery and equipment without causing significant environmental harm.
It is also extensively used in industries like oil and gas for cleaning pipelines, removing deposits, and enhancing the efficiency of drilling fluids, contributing to more sustainable and cost-effective operations.
Safety profile Of Tetrasodium Glutamate Diacetate (GLDA):
The safety of Tetrasodium Glutamate Diacetate (GLDA) was assessed by the Expert Panel for Cosmetic Ingredient Safety (formerly called the Cosmetic Ingredient Review Expert Panel) in 2021.
The Expert Panel concluded that it was safe as used in the present practices of use and concentration in cosmetics and personal care products.
The Expert Panel noted Tetrasodium Glutamate Diacetate (GLDA) is slowly absorbed through the gastrointestinal tract and skin absorption is likely to be even slower.
The Expert Panel also noted the lack of carcinogenicity (cancer-causing potential) data and that it may contain a salt of nitrilotriacetic acid, a category 2B carcinogen according to the International Agency for Research on Cancer (IARC).
However, the concern was mitigated by multiple genotoxicity studies (both in vitro and in vivo), which did not indicate adverse genetic activity at the low concentrations of this ingredient in leave-on products.
