PRODUCTS

TETRASODIUM N,N-BIS(CARBOXYLATOMETHYL)-L-GLUTAMATE

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a biodegradable, high-performance chelating agent derived from natural, renewable raw materials, making it an eco-friendly alternative to traditional chelating agents such as EDTA, NTA, and phosphates.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is highly effective at low concentrations across a wide pH range, enhancing product stability and preventing discoloration in formulations.
With excellent biodegradability and a non-toxic profile, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate supports environmentally friendly and sustainable applications in cosmetics, detergents, and industrial cleaners.

CAS Number: 51981-21-6
EC Number: 257-573-7
Molecular Formula: C9H9NO8Na4
Molecular Weight: 351.07 g/mol

Synonyms: GLDA 4NA %47 , TETRASODIUM GLUTAMATE DIACETATE %47 , Chelating agent GLDA %47 , Potassium molybdate 13446-49-6;6-dioxo-3-piperidinyl)-5-fluoro-, TETRASODIUM DICARBOXYMETHYL GLUTAMATE %47 , Tetrasodium glutamate diacetate (GLDA) %47 , Tetrasodium N,N-bis(carboxylatomethyl) %47 , Tetrasodium glutamate diacetate (GLDA), Tetrasodium N,N-bis(carboxylatomethyl), (2S)-2-[Bis(carboxylatométhyl)amino]pentanedioate de tétrasodium , 257-573-7 , L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4) , Tetranatrium-(2S)-2-[bis(carboxylatomethyl)amino]pentandioat , 51981-21-6, tetrasodium glutamate diacetate %47, GLDA %47, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, 5EHL50I4MY, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), EINECS 257-573-7, EC 257-573-7, TETRASODIUM GLUTAMATE DIACETATE %47, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT %47, Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT %47, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT %47, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT %47, tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate), GLDA %47, TETRASODIUM GLUTAMATE DIACETATE %47, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, Chelating agent GLDA %47, Potassium molybdate 13446-49-6;6-dioxo-3-piperidinyl)-5-fluoro-, TETRASODIUM DICARBOXYMETHYL GLUTAMATE %47, Tetrasodium (2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, 51981-21-6, MFCD01862262, N, N-Bis(Carboxymethyl)-L-glutamic acid tetrasodium salt, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt, N,N-bis-(Carboxymethyl)-L-glutamic acid tetrasodiumn salt, Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, TETRASODIUM GLUTAMATE DIACETATE, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, TETRASODIUM N,N-BIS(CARBOXYMETHYL)-L-GLUTAMATE

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a biodegradable, high-performance chelating agent widely used in various industrial and consumer applications.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is derived from natural, renewable raw materials, making it an eco-friendly alternative to traditional chelating agents such as EDTA, NTA, and phosphates.

The "4NA" refers to its tetrasodium salt form, while "47%" indicates its concentration in aqueous solution, ensuring ease of handling and formulation in liquid products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is known for its exceptional chelating ability, effectively binding to metal ions such as calcium, magnesium, iron, and heavy metals.

This property prevents undesirable reactions caused by metal ions in formulations, enhancing the stability and performance of products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate's versatility and excellent solubility across a wide pH range (from acidic to alkaline) make it suitable for use in detergents, personal care products, industrial cleaners, and agricultural formulations.

Compared to conventional chelating agents, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate exhibits improved biodegradability, meeting stringent environmental standards and reducing the ecological footprint of end products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate's mild nature and non-toxic profile make it compatible with sensitive skin, making it a preferred choice in cosmetics and personal care applications.

Additionally, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate improves the efficacy of active ingredients, enhances stain removal in detergents, and boosts cleaning performance in industrial and household cleaning solutions.
The chelating agent also finds applications in water treatment, where it prevents scale formation and enhances the efficiency of water-softening processes.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate's high thermal and chemical stability ensures reliable performance even under harsh conditions, such as high temperatures and strong alkaline environments.
Overall, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate offers a sustainable, efficient, and multifunctional solution for industries seeking to balance performance with environmental responsibility.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, and other products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in detergents, cleansing wipes, bar soap, and other cleaning products.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate usually appears as an odourless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a safe synthetic chelating agent with natural origins.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a rinsing aid.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is readily biodegradable
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can be considered as one of the most environmentally friendly chelators without compromising product performance.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a concentrated aqueous solution of an amino acid based natural chelating agent.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is highly effective at low concentrations of water at a very wide acidic and alkaline pH range.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is readily biodegradable and can be considered as one of the most environmentally friendly chelators without compromising product performance.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a NTA-free, environmental friendly and biodegradable chelating agent based on natural source.
As an alternative to NTA and EDTA the chelating Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in industrial and household cleaners for improving the detergency.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a strong chelating agent for metal ions, which can form stable and water-soluble complex compounds.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can easily be used in a wide pH-range.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used to enhance and preservative the formulation’s ingredients and also acts as a heavy metal chelating agent.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a chelating agent and preservative enhancer.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in cosmetics mainly because of its ability to boost the effectiveness of other preservatives.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is also used to stabilise the ingredients of cosmetic formulations, preventing the natural discolouration of shampoos and gels.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is made from plant material, readily biodegradable, with high solubility over a wide pH range

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a naturally and sustainably produced sequestrant derived from the Amino Acid Glutamic acid.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamateis Tetrasodium Glutamate Diacetate with a concentration about 47%
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is aminopolycarboxylate-based chelating agent based on the food-approved natural amino acid salt

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is monosodium L-glutamate, which is produced by biochemical conversion of vegetable material (such as sugar beet waste).
This results in a good biological breakdown as is confirmed biodegradability test.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is readily biodegradable, with a high solubility over a wide pH range.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate does not sensitize human skin

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can be used in many applications such as industrial and household cleaners for improving the detergency.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate when added to a formulation can help stabilise the product and prevent discoloration.

In larger quantities Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate will enhance the cleaning ability and prevent deactivation of active ingredients during use.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate also reduces the effect of Calcium and Magnesium ions resulting in better surfactant performance.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is suitable to be used in personal care and cosmetics products, due to the strong chelating ability of calcium and transition metal ions prolonging the shelf life of many products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, and other products.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in detergents, cleansing wipes, bar soap, and other cleaning products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a rinsing aid.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can easily be used in a wide pH-range.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate also helps to maintain clarity, protect fragrance compounds and prevent rancidity.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in bath soaps, detergents and non-spray deodorant product.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate widely used in personal care, cleaning and detergents, industrial cleaning and oil industry.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a chelating agent that binds to metal ions.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is made from plant material.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate usually appears as an odourless white powder that is soluble in water.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used as a multi-purpose, clear, liquid chelating agent and preservative booster.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a powerful chelating agent made from natural, biodegradable, renewable raw materials and also functions as an effective preservative booster.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate complexes hard water ions effectively whilst retaining its high chelating value at elevated temperatures compared to other chelating agents.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can be used as a more sustainable alternative to phosphonates and commonly used chelating agents (NTA and EDTA) in a wide number of applications.

Produced from a naturally occurring amino acid, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is readily biodegradable with a high level of solubility over a wide pH range and is thus a greener alternative to many other chelates.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can be used to replace EDTA in a 1:1 ratio in many applications and products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate also does not sensitise human skin and provides enhanced biocidal/preservative boosting power when compared to commonly used boosters such as EDTA and NTA.

Uses of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate also helps to maintain clarity, protect fragrance compounds and prevent rancidity.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in bath soaps, detergents and non-spray deodorant product.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in boost the effectiveness of preservatives.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate widely used in personal care, cleaning and detergents, industrial cleaning and oil industry.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a chelating agent that binds to metal ions.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a multi-purpose, clear, liquid.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is chelating agent.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is preservative booster.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is made from plant material.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate demonstrates enhanced biocidal boosting power and improved biodegradability properties.
Compared to phosphates and phosphonates, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is a far more effective chelating agent.

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, and other products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can be found in detergents, cleansing wipes, bar soap, and other cleaning products

Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate usually appears as an odourless white powder that is soluble in water
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used as a multi-purpose, clear, liquid chelating agent and preservative booster.

Detergents and Cleaning Products:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate acts as a chelating agent to enhance stain removal and cleaning efficacy.
Prevents redeposition of dirt and minerals on surfaces during cleaning.
Effective in laundry detergents, dishwashing liquids, and multi-purpose cleaners.

Personal Care and Cosmetics:
Stabilizes formulations by binding metal ions that could degrade products.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in shampoos, conditioners, and facial cleansers to enhance mildness and efficacy.
Compatible with sensitive skin due to Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate's non-toxic and gentle nature.

Industrial Applications:
Improves the performance of industrial cleaners by preventing scale formation.
Enhances the stability of alkaline and acidic cleaning solutions.
Suitable for applications such as metal cleaning, degreasing, and car washing products.

Agriculture
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in agricultural formulations to improve nutrient availability by chelating essential metal ions.
Helps stabilize micronutrient solutions in fertilizers.

Water Treatment:
Prevents scale formation and buildup in water systems by chelating calcium and magnesium ions.
Enhances the efficiency of water-softening processes in industrial and domestic settings.

Food Industry:
Approved for use in certain food applications as a sequestrant and stabilizer.
Improves shelf life and quality by preventing discoloration and oxidative degradation.

Pharmaceuticals and Biotechnology:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate acts as a stabilizer in drug formulations.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in laboratory applications for metal ion chelation in experimental procedures.

Eco-Friendly Applications:
Suitable for biodegradable and environmentally sustainable product formulations.
Provides a green alternative to traditional chelating agents like EDTA and phosphates.

Consumer Uses:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used in the following products: washing & cleaning products, polishes and waxes, air care products and biocides (e.g. disinfectants, pest control products).
Other release to the environment of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Widespread uses by professional workers:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Other release to the environment of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Uses at industrial sites:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid, of substances in closed systems with minimal release and in processing aids at industrial sites.

Applications of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
Automatic dishwash tabs, gels and capsules
Cleaning products
Cosmetics
Descaling
Personal care
Industrial cleaning
Pulp bleaching
Water treatment
Industrial detergents and cleaners
Hard surface cleaners
Dishwashing detergents
Laundry detergents HDL and LDL
Paper industry
Cosmetic/ personal care products
Textile auxiliaries
Preservative booster

Benefits of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
biodegradable & non toxic
Scale prevention and removal
Improves the bleaching process
Produced from Bio-based raw material (L-Glutamic acid)

Production of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
The production of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate involves a series of chemical reactions and purification steps designed to yield a high-performance, biodegradable chelating agent derived from natural, renewable resources.
GLDA, a derivative of glutamic acid, is synthesized primarily using processes that emphasize sustainability and eco-friendliness.

Raw Materials:
The key raw material for GLDA production is L-glutamic acid, an amino acid that can be sourced from renewable agricultural products such as corn, sugarcane, or molasses.
This ensures that the process aligns with green chemistry principles.
Additional reagents include acetic acid, caustic soda (sodium hydroxide), and formaldehyde, which are used to achieve the desired chemical transformations.

Synthesis Process:

The production involves the following key steps:

Derivatization of Glutamic Acid:
Glutamic acid is reacted with acetic acid and formaldehyde under controlled conditions to introduce the diacetate functional groups.
This reaction forms glutamic diacetate, a precursor to the chelating agent.

Neutralization:
The intermediate glutamic diacetate is neutralized with sodium hydroxide (NaOH) to form the tetrasodium salt of glutamic diacetate.
This step ensures the final product is in its highly soluble sodium salt form, suitable for liquid formulations.

Dilution to Desired Concentration:
The resulting tetrasodium glutamate diacetate solution is adjusted to a 47% concentration in water.
This concentration provides an optimal balance of chelating efficiency, ease of handling, and compatibility with various formulations.

Purification and Quality Control:

Purification:
The solution is subjected to filtration to remove any insoluble impurities and ensure a clear, high-purity product.
Advanced techniques, such as ion-exchange filtration, may be used to eliminate residual unreacted materials.

Quality Testing:
Stringent quality checks are performed to ensure compliance with specifications.
Parameters such as concentration, pH, metal-binding capacity, and biodegradability are verified.

Environmental Considerations:

The production of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is designed to minimize environmental impact:
Renewable raw materials reduce reliance on petrochemicals.
The process generates low waste and utilizes water as the primary solvent.
Byproducts are minimal and typically non-toxic, supporting sustainable manufacturing practices.

Packaging and Storage:
The final product is packaged in corrosion-resistant containers, such as high-density polyethylene (HDPE) drums or intermediate bulk containers (IBCs), to prevent contamination and maintain product integrity.
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate is then stored in cool, dry conditions away from direct sunlight to preserve its stability.

Industrial Scale Production:
On an industrial scale, the process is carried out in reactors with precise temperature and pH controls to ensure high yields and consistent product quality.
Automation and monitoring systems help optimize the process and reduce energy consumption.

The production of Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate exemplifies the shift towards sustainable and green chemistry practices, providing a chelating agent that meets modern environmental and performance standards while serving diverse industrial applications.

Handling and Storage of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Handling:
Use with adequate ventilation to prevent inhalation of mists.
Avoid contact with eyes, skin, and clothing.

Wear appropriate personal protective equipment (PPE).
Wash thoroughly after handling.
Prevent release into the environment.

Storage:
Store in a cool, dry, and well-ventilated area.
Keep container tightly closed when not in use.

Protect from direct sunlight and extreme temperatures.
Avoid storage near incompatible materials like strong oxidizers or acids.

Stability and Reactivity of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Chemical Stability:
Stable under normal temperature and storage conditions.

Conditions to Avoid:
Avoid extreme heat, freezing, and exposure to incompatible substances.

Incompatible Materials:
Strong oxidizing agents, strong acids, and reactive metals.

Hazardous Decomposition Products:
May produce carbon oxides (CO and CO₂) and nitrogen oxides under combustion.

First Aid Measures of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes.
Remove contact lenses if present and easy to do.
Seek medical attention if irritation persists.

Skin Contact:
Wash affected area with soap and water.
Remove contaminated clothing and wash before reuse.
Seek medical attention if irritation develops.

Inhalation:
Move to fresh air.
If breathing difficulty occurs, seek medical assistance.
Administer artificial respiration if breathing stops.

Ingestion:
Rinse mouth with water.
Do not induce vomiting unless instructed by medical personnel.
Seek medical attention immediately.

Firefighting Measures of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Suitable Extinguishing Media:
Water spray, foam, dry chemical, or CO₂.

Special Protective Equipment for Firefighters:
Use self-contained breathing apparatus (SCBA) and full protective gear.

Fire Hazards:
Not considered flammable.
Combustion may release toxic gases such as carbon oxides and nitrogen oxides.

Specific Firefighting Measures:
Cool exposed containers with water spray to prevent overheating.

Accidental Release Measures of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Personal Precautions:
Use PPE such as gloves, safety goggles, and respiratory protection if needed.
Avoid direct contact with spilled material.

Environmental Precautions:
Prevent entry into waterways, sewers, and soil.
Notify authorities if large quantities are released.

Containment and Cleanup:
Absorb with inert material like sand, earth, or vermiculite.
Collect in suitable, labeled containers for proper disposal.
Wash the area thoroughly after cleanup.

Exposure Controls/Personal Protective Measures of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Engineering Controls:
Use local exhaust ventilation to minimize exposure.
Ensure good general ventilation in the work area.

Personal Protective Equipment (PPE):

Eye/Face Protection:
Safety goggles or face shield.

Skin Protection:
Chemical-resistant gloves and protective clothing.

Respiratory Protection:
Approved respirator if mists or vapors are present.

Footwear:
Closed-toe, chemical-resistant footwear.

Exposure Limits:
No specific occupational exposure limits established.
Use general guidelines for safe handling.

Hygiene Measures:
Wash hands, face, and exposed areas thoroughly after handling.
Avoid eating, drinking, or smoking during use.

Identifiers of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
CAS NUMBER: 51981-21-6
EC NUMBER: 257-573-7
MOLECULAR FORMULA: C9H9NNa4O8
MOLECULAR WEIGHT: 351.13
IUPAC NAME: tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate

Molecular Formula: C9H9NO8Na4
Molecular Weight: 351.1
CAS No.: 51981-21-6

CAS Number: 51981-21-6
Molecular Formula: C9H9NO8Na4
Molecular Weight: 351.07 g/mol
EC Number: 257-573-7
Functional groups: Carboxylic acid salts, diacetate groups
IUPAC Name: Tetrasodium 2-[bis(carboxylatomethyl)amino]pentanedioate
PubChem CID: 6328359

InChI: InChI=1S/C9H13NO8.4Na/c11-7(12)3-6(4-8(13)14)10(5-9(15)16)2-1-10;;;;/h6H,1-5H2,(H,11,12)(H,13,14)(H,15,16);;;;/q;4*+1/p-4
InChI Key: VSFCKIRHTDREHO-UHFFFAOYSA-J
SMILES: C(C(=O)O)C(C(=O)O)N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+]
CAS Number: 51981-21-6
Exact Mass: 350.993 g/mol
Monoisotopic Mass: 350.993 g/mol
UNII Code: 7M6EZX9CLT

Properties of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
Concentration: 47% aqueous solution
pH (1% solution): 11–12
Appearance: Clear to pale yellow liquid
Solubility: Highly soluble in water

Molecular Weight: 351.13
Exact Mass: 350.99189337
Monoisotopic Mass: 350.99189337
Topological Polar Surface Area: 164 Å²
Density: 1.466
Vapor Pressure: 80Pa
StorageTemperature: Refrigerator
Solubility: Soluble in Water
Form: Colourless Solution
Color: Light orange to Yellow to Green
Water Solubility: 650g/L
Physical Description: Pellets or Large Crystals

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 5
Heavy Atom Count: 22
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes

Specifications of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:
Appearance: Clear to pale yellow liquid
Odor: Odorless or faint characteristic odor
pH (1% Solution): 11.0–12.0
Density: ~1.28 g/cm³ at 20°C
Solubility: Completely soluble in water
Boiling Point: ~100°C (aqueous solution)
Freezing Point: <0°C

GLDA Content: 46–48%
Tetrasodium Salt Content: ~100% of GLDA present
Impurities: Minimal, typically <0.5% by weight

Names of Tetrasodium N,N-Bis(Carboxylatomethyl)-L-Glutamate:

Regulatory process name:
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate

IUPAC names:
Glutamic acid, N,N-diacetic acid, tetrasodium salt
N,N-dicarboxymethyl L-glutamic acid tetra sodium salt
tetrasodium (2S)-2-[bis(carboxylatomethyl)amino]pentanedioate
tetrasodium (2S)-2-[bis(carboxymethyl)amino]pentanedioate
tetrasodium (S)-2-[bis(carboxylatomethyl)amino]pentanedioate
tetrasodium 2-[bis(carboxylatomethyl)amino]pentanedioate
Tetrasodium Glutamate Diacetate
Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate
tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate

Trade names:
Dissolvine GL-38
Dissolvine GL-45-SLA
Dissolvine GL-47-S
Dissolvine Gl-74 (old trade name)
Dissolvine GL-PD
Dissolvine GL-PD-S
GLDA
GLDA 4Na
Nervanaid GBS5 (old trade name)
Tetrasodium N,N-bis(carboxylatomethyl)-Lglutamate (GLDA-4NA)

Other identifier:
51981-21-6