THIRAM

Thiram is designed for the rubber industry. 
All grades are white to off white.
Thiram offers fast vulcanization and gives an excellent vulcanization plateau with good heat aging and compression set resistance when used in sulfurless vulcanization systems and EV systems.

CAS Number: 137-26-8
EC Number: 205-286-2
IUPAC Name: dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
Chemical Formula: C6H12N2S4

Other names: 137-26-8, Thiuram, Rezifilm, TMT, Pomarsol, ThirameArasan, Fernasan, Nobecutan, Thioscabin, Thirasan, Aapirol, Tersan, Tetrathiuram disulfide, Tetramethylthiuram, Falitiram, Formalsol, Hexathir, Kregasan, Mercuram, Normersan, Sadoplon, Spotrete, Tetrasipton, Thillate, Thiramad, Aatiram, Atiram, Fermide, Fernide, Hermal, Pomasol, Puralin, Thiosan, Thiotox, Thiulin, Thiulix, Heryl, Pomarsol forte, Methyl tuads, Accelerator T, Methyl Thiram, Fernasan A, Tetramethylthiuram disulphide, Nocceler TT, Arasan-M, Bis(dimethylthiocarbamoyl) disulfide, Thiram B, Arasan-SF, Cyuram DS, Ekagom TB, Hermat TMT, Tetramethylenethiuram disulfide, Accel TMT, Accelerator thiuram, Aceto TETD, Radothiram, Royal TMTD, Tetramethyl-thiram disulfid, Fernacol, Sadoplon 75, Tetramethylthiuram bisulfide, Tetrapom, Thioknock, Thirampa, Thiramum, Anles, Arasan-SF-X, Aules, Thimer, Panoram 75, Tetramethylthiouram disulfide, Tetramethylthiurane disulfide, Arasan 70, Arasan 75, Tersan 75, Thiram 75, Thiram 80, Spotrete-F, TMTDS, Arasan 70-S Red, Tetramethylthioperoxydicarbonic diamide, Methylthiuram disulfide, N,N-Tetramethylthiuram disulfide, Metiurac, Micropearls, Nomersan, Thianosan, Cunitex, Delsan, Thimar, Teramethylthiuram disulfide, Tersantetramethyldiurane sulfide, Pol-Thiuram, Arasan 42-S, Tetramethylthiurum disulfide, Disulfure de tetramethylthiourame, Tetrathiuram disulphide, Sranan-sf-X, Hy-Vic, SQ 1489, Chipco thiram 75, Bis(dimethyl-thiocarbamoyl)-disulfid, Orac TMTD, Tetramethylthioramdisulfide, Tetramethyldiurane sulphite, Thiotox (fungicide), Disulfide, bis(dimethylthiocarbamoyl), Bis((dimethylamino)carbonothioyl) disulfide, Fermide 850, Tetramethyl thiuramdisulfide, Tetramethylthiocarbamoyldisulphide, Thiuramyl, Thylate, Methyl thiuramdisulfide, Bis(dimethylthiocarbamyl) disulfide, Tetramethyl thiurane disulfide, Bis(dimethyl thiocarbamoyl)disulfide, Thirame, Thiramum, Disolfuro di tetrametiltiourame, Tetramethyl thiurane disulphide, Tetramethylenethiuram disulphide, N,N'-(Dithiodicarbonothioyl)bis(N-methylmethanamine), RCRA waste number U244, Flo Pro T Seed Protectant, Tetramethylthiuram bisulphide, Tetramethylthiuran disulfide, Tetramethylthiurum disulfide, NSC-1771, Tetramethyl thiuram disulfide, alpha,alpha'-Dithiobis(dimethylthio)formamide, Thiotex, Thiurad, Tirampa, Tiuramyl, Trametan, Tridipam, Tripomol, Tyradi, Tuads, Tutan, Vulkacit mtic, N,N,N',N'-Tetramethylthiuram disulfide, N,N-Tetramethylthiuram disulphide, Vulkacit thiuram, Thioperoxydicarbonic diamide, tetramethyl-, Thiuram M, Vulkacit TH, Tetramethylthioramdisulfide [Dutch], Vulcafor TMT, Vulcafor TMTD, Bis((dimethylamino)carbonothioyl) disulfide, FMC 2070, Bis(dimethylthiocarbamoyl) disulfide, Tetramethyl-thiram disulfid [German], Formamide, 1,1'-dithiobis(N,N-dimethylthio-, dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate, Zaprawa Nasienna T, [Me2NC(S)S]2, Vancida tm-95, Disulfuro di tetrametiltiourame, Arasan 42S, TUEX, Disolfuro di tetrametiltiourame, Disulfuro di tetrametiltiourame, Disulfure de tetramethylthiourame, NSC1771, Bis(dimethyl-thiocarbamoyl)-disulfid, VUAgT-I-4, NSC-49512, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetramethyl-, NSC-622696, [disulfanediylbis(carbonothioylnitrilo)]tetramethane, Thiuram M rubber accelerator, MLS000069752, MLS002702972, 0D771IS0FH, CHEBI:9495, Thiuram disulfide, tetramethyl-, DTXSID5021332, Thiuram-M, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-, NSC4951, CCG-35460, NSC-59637, NSC622696, TNTD, SQ-1489, NCGC00091563-01, SMR000059023, Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetramethyl-, [dithiobis(carbonothioylnitrilo)]tetramethane, .alpha.,.alpha.'-Dithiobis(dimethylthio)formamide, Caswell No. 856, Granuflo, N,N-dimethyl[(dimethylcarbamothioyl)disulfanyl]carbothioamide, Thiuramin, N,N',N'-Tetramethylthiuram disulfide, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetramethyl-, CAS-137-26-8, Formamide,1'-dithiobis(N,N-dimethylthio-, Bis[(dimethylamino)carbonothioyl] disulfide, Attack, Thiram [ISO], NSC59637, CCRIS 1282, HSDB 863, ENT 987, WLN: 1N1 & YUS & SSYUS & N1 & 1, NSC 1771, EINECS 205-286-2, NSC 49512, NSC 59637, RCRA waste no. U244, EPA Pesticide Chemical Code 079801, NSC 622696, BRN 1725821, tiramo, UNII-0D771IS0FH, BasultraBetoxin, TiradinAccelerant T, AI3-00987, Arasan, Vulkazam S, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N',N'-tetramethyl-, Vanguard GF, Vancide TM, Akrochem TMTD, Perkacit TMTD, Vulkacit DTMT, Robac TMT, Thiram (Tmtd), Rezifilm (TN), Arasan 50 red, Spotrete WP 75, MFCD00008325, Vancide TM-95, Naftocit thiuram 16, Spectrum_001687, Thiram (USAN/INN), Agrichem flowable thiram, THIRAM [HSDB], THIRAM [IARC], THIRAM [INCI], THIRAM [USAN], THIRAM [INN], Spectrum2_001554, Spectrum3_001592, Spectrum4_000860, Spectrum5_001653, THIRAM [WHO-DD], THIRAM [MI], THIRAM [MART.], bmse000928, EC 205-286-2, NCIMech_000272, cid_5455, NCIOpen2_007854, SCHEMBL21144, BSPBio_003184, KBioGR_001499, KBioSS_002167, 4-04-00-00242, BIDD:ER0359, DivK1c_000741, SPECTRUM1503322, SPBio_001428, CHEMBL120563, Thiram [USAN:INN:BSI:ISO], BDBM43362, HMS502F03, KBio1_000741, KBio2_002167, KBio2_004735, KBio2_007303, KBio3_002684, KUAZQDVKQLNFPE-UHFFFAOYSA-, ENT-987, NINDS_000741, HMS1922A12, HMS2093E03, HMS2234B08, HMS3374C05, Pharmakon1600-01503322, Tetramethylthiuram disulfide, 97%, ZINC1532176, Tox21_111150, Tox21_201569, Tox21_301102, NSC758454, s2431, STL264104, (dimethylamino){[(dimethylamino)thioxomethyl]disulfanyl}methane-1-thione, AKOS000120200, bis (dimethyl thiocarbamoyl) disulfide, Bis(dimethylaminothiocarbonyl)disulfide, Tox21_111150_1, bis(dimethylaminothiocarbonyl) disulfide, DB13245, KS-5354

Thiram is a valuable secondary accelerator.
In mercaptan modified polychloroprene cured with ETU, Thiram acts as a scorch retarder without affecting the cure speed.
Thiram is recommended for use in soft compounds due to dispersability.
Thiram is non-staining and non-discoloring. 
Excellent colors are obtained in non-black vulcanizates.

Thiram should be noted that in the application of Dimacit TMTD N-nitrosodimethylamine can be formed by the reaction of dimethylamine, a decomposition product, with nitrosating agents (nitrogen oxides).
Thiram is used as a fungicide, bacteriostat and pesticide. 
Thiram is also used in the processing of rubber and in the blending of lubricant oils. 
Thiram can be found in products such as seed disinfectants, antiseptic sprays, animal repellents, insecticides, wood preservatives, some soaps, rodent repellents and as a nut, fruit and mushroom disinfectant.

Thiram is widely used in rubber processing as an ultra accelerator for low-temperature cures, either alone or as an activator for other accelerators, chiefly the thiazoles.
Thiram can reduce the growth performance of chickens through decreasing liver index, whereas increasing kidney, cardiac, and spleen index, and induces tibial dyschondrolplasia (TD) by changing the expressions of VEGF, HIF-1α and WNT4. 
Thiram is widely used in rubber processing as an ultra accelerator for low-temperature cures and in agriculture as an important pesticide.
Thiram is an accelerator found in the rubber industry.

Thiram appears as a liquid solution of a white crystalline solid. 
Primary hazard is to the environment. 
Immediate steps should be taken to limit spread to the environment. 
Easily penetrates the soil to contaminates groundwater and waterways.
Thiram is an organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. 

Thiram is widely used as a fungicidal seed treatment. 
Thiram has a role as an antibacterial drug, an antiseptic drug and an antifungal agrochemical. 
Thiram contains a dimethyldithiocarbamate. 
Thiram is functionally related to a dimethyldithiocarbamic acid.
Thiram is an ectoparasiticide. 

Thiram is used to prevent fungal diseases in seed and crops. 
Thiram is also used as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. 
Thiram is effective against Stem gall of coriander, damping off, smut of millet, neck rot of onion, etc. 
Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap.
Thiram is a class of organosulfur compounds with the formula (R2NCSS)2.

Many examples are known, but popular ones include R = Me and Et. 
They are disulfides obtained by oxidation of the dithiocarbamates. 
These compounds are used in sulfur vulcanization of rubber as well as pesticides and drugs. 
They are typically white or pale yellow solids that are soluble in organic solvents.
Thiram is a widely used fungicide. 
Thiram is commonly used to treat chronic alcoholism. 

Thiram produces an acute sensitivity to alcohol ingestion by blocking acetaldehyde dehydrogenase conversion of acetaldehyde leading to a higher concentration of the aldehyde in the blood producing symptoms of a severe hangover.
Thiram is an ectoparasiticide. 
Thiram is used in agriculture to prevent fungal diseases in seed and crops. 
Thiram has other applications ranging from use as a topical bactericide to animal repellent.

APPLICATION:
Thiram can be used as a single accelerator, as a secondary accelerator or as a sulphur donor in most sulphur-cured elastomers. 
Scorchy and gives fast cure rates. 
Thiram produces an excellent vulcanisation plateau with good heat aging and compression set resistance in sulphurless and EV cure systems Good color retention is obtained in non-black vulcanisation. 
A valuable secondary accelerator for EPDM. 
Thiram may be used as a retarder in the vulcanisation of polychloroprene rubber with ETU and also be used as bactericide and pesticide.

Rubber and plastic additives
Rubber modification

USES:
Without sulphur (2 -4% on the weight of the gum),
With sulphur in conjunction with zinc oxide and fatty acid as activators (0.1 - 1% TMTD on the weight of the gum),
In conjunction with accelerators such as mercaptobenzothiazole (0.25 – 0.5 TMTD on the weight of the gum).

TECHNICAL INFORMATION:
Appearance: Powder
Physical State: Solid
Solubility: Soluble in CHCl3: 50 mg/ml
Storage: Store at room temperature
Melting Point: 156-158° C (lit.)
Density: 1.43 g/cm3 at 20° C
Refractive Index: n20D 1.68  
pK Values: pKb: 0.87 

STORAGE:
Thiram should be stored in the dry and cooling place with good ventilation, avoiding exposure of the packaged product to direct sunlight.
Store in dry well ventilated place away from foodstuffs.