Quick Search
TIB KAT MSA 99 is a catalyst based on methane sulfonic acid.
TIB KAT MSA 99 is used in Chemical industry as catalyst and Additive and in Electroplating industry for different applications in plating baths.
TIB KAT MSA 99 is a strong organic acid.
CAS: 75-75-2
MF: CH4O3S
MW: 96.11
EINECS: 200-898-6
Synonyms
acidemethanesulfonique;Kyselina methansulfonova;kyselinamethansulfonova;Methylsulphonicacid;SULFOMETHANE;MSA;METHANE SULFONIC ACID 70%;METHANESULFONIC ACID 4.0 M WITH 0.2%*(W/ V) TRYPTAMI
The chemical oxidation of dimetyl sulfide in the atmosphere leads to the formation of TIB KAT MSA 99 in large quantities.
TIB KAT MSA 99 undergoes biodegradation by forming CO2 and sulphate.
TIB KAT MSA 99 is considered a green acid as it is less toxic and corrosive in comparison to mineral acids.
TIB KAT MSA 99 has been considered a model electrolyte for electrochemical processes.
TIB KAT MSA 99 is an alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl.
TIB KAT MSA 99 has a role as an Escherichia coli metabolite.
TIB KAT MSA 99 is an alkanesulfonic acid and a one-carbon compound.
TIB KAT MSA 99 is a conjugate acid of a methanesulfonate.
TIB KAT MSA 99 is a strong organic acid.
The chemical oxidation of dimetyl sulfide in the atmosphere leads to the formation of TIB KAT MSA 99 in large quantities.
TIB KAT MSA 99 undergoes biodegradation by forming CO2 and sulphate.
TIB KAT MSA 99 is considered a green acid as it is less toxic and corrosive in comparison to mineral acids.
TIB KAT MSA 99 has been considered a model electrolyte for electrochemical processes.
TIB KAT MSA 99 Chemical Properties
Melting point: 17-19 °C (lit.)
Boiling point: 167 °C/10 mmHg (lit.)
Density: 1.475-1.485 g/mL at 20 °C 1.481 g/mL at 25 °C (lit.)
Vapor density: 3.3 (vs air)
Vapor pressure: 1 mm Hg ( 20 °C)
Refractive index: n20/D 1.429(lit.)
Fp: >230 °F
Storage temp.: 2-8°C
Solubility: water: soluble1,000 g/L at 20°C
Pka: -2.6(at 25℃)
Form: Solution
Color: brown
Specific Gravity: 1.48 (18/4℃)
Biological source: synthetic
Water Solubility: Miscible with water. Slightly miscible with benzene and toluene. Immiscible with paraffins.
λmax λ: 240-320 nm Amax: <0.4
Sensitive: Light Sensitive & Hygroscopic
Merck: 14,5954
BRN: 1446024
Stability: Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).
InChIKey: AFVFQIVMOAPDHO-UHFFFAOYSA-N
CAS DataBase Reference: 75-75-2(CAS DataBase Reference)
NIST Chemistry Reference: CH3SO3H(75-75-2)
EPA Substance Registry System: TIB KAT MSA 99 (75-75-2)
TIB KAT MSA 99, the simplest alkanesulfonic acid, is a colorless or slightly brown oily liquid, appearing as solid at low temperatures.
TIB KAT MSA 99 has a melting temperature of 20 °C, the boiling point of 167 °C (13.33 kPa), 122 °C (0.133 kPa), the relative density of 1.4812 (18 ℃) and refractive index 1.4317 (16 ℃).
TIB KAT MSA 99 is soluble in water, alcohol and ether, insoluble in alkanes, benzene and toluene.
TIB KAT MSA 99 will not subject to decomposition in boiling water and hot alkaline solution.
TIB KAT MSA 99 also has strong corrosion effect against the metal iron, copper and lead.
Uses
TIB KAT MSA 99 is a raw material for medicine and pesticide.
TIB KAT MSA 99 can also be used as dehydrating agent, curing accelerator for coating, treating agent for fiber, solvent, catalysis, and esterification as well as polymerization reaction.
TIB KAT MSA 99 can be used as solvent, alkylation, catalyst of esterification and polymerization, also used in medicine and electroplating industry.
TIB KAT MSA 99 can also be applied to oxidation.
TIB KAT MSA 99 is used as a catalyst in organic reactions namely esterification, alkylation and condensation reactions due to its non- volatile nature and solubility in organic solvents.
TIB KAT MSA 99 is also involved in the production of starch esters, wax oxidate esters, benzoic acid esters, phenolic esters, or alkyl esters.
TIB KAT MSA 99 reacts with sodium borohydride in presence of polar solvent tetrahydrofuran to prepare borane-tetrahydrofuran complex.
TIB KAT MSA 99 finds application in batteries, because of its purity and chloride absence.
In pharmaceutical industry, TIB KAT MSA 99 is used for the manufacturing of active pharmaceutical ingredients like telmisartan and eprosartan.
TIB KAT MSA 99 is useful in ion chromatography and is a source of carbon and energy for some gram-negative methylotropic bacteria.
TIB KAT MSA 99 is involved in the deprotection of peptides.
Production method
TIB KAT MSA 99 can be obtained through the nitrate oxidation of thiocyanate methyl.
Nitric acid and negative water are heated carefully to 80-88 °C with fractional addition of methyl thiocyanate and the temperature being automatically rose to about 105 ℃.
After the reaction becomes mild, the reaction was heated to 120 ° C and reacted for 5 hours to obtain a crude product.
The crude product was diluted with exchanged water and adjusted to pH 8-9 by addition of 25% barium hydroxide solution and filtered.
The filtrate is condensed to until crystalline precipitation.
The crystal is washed by methanol to remove the nitrate to obtain the barium methanesulfonate.
TIB KAT MSA 99 is then added to the exchanged water to boiling, add sulfuric acid for decomposition while it is hot, filter and the filtrate was concentrated under vacuum to no water to obtain the finished product.
Another method is that the methyl isothiourea sulfate is successively subject to chlorination, oxidation and hydrolysis to derive the finished product.
Methyl isothiourea sulfate was added to the water; and the chlorine is sent into at 20-25 ° C to until phenomenon such as solution color is turned into yellow; oil layer emerges in the bottom of the bottle; the temperature drop and large number of residual chlorine is discharged from the exhaust pipe; this indicates the end point of the reaction.
The reaction solution was extracted with chloroform.
After drying, the extract was distilled at 60-62 ° C under normal pressure to remove the chloroform, and then further subject to distillation under reduced pressure.
Collect the 60-65 °C (2.67 kPa) fraction was to obtain the methanesulfonyl chloride.
Add the base drop wise under stirring to 80 ℃ hot water and maintain the heat hydrolysis for about 2h, to until the reaction liquid droplets completely disappear.
The reaction solution was concentrated under reduced pressure to a syrupy form, diluted with water, and concentrated under reduced pressure to until no more water was distilled off to obtain methanesulfonic acid.
