TRIACETIN IBC

Synonyms:
1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glyceryl triacetate; TRİ ASETİN; TRİASETİN; TRI ACETIN; TRIACETIN; tri asetin; triasetin; triacetin; tri acetin;Triacetin; Glyceryl triacetate; 102-76-1; Glycerol triacetate; Glycerin triacetate; Enzactin ;1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glyceryl triacetate;Triacetin;1,2,3-Triacetoxypropane;1,2,3-Propantriyl-triacetat;1,2,3-Propanetriyl triacetate;1,2,3-Propanetriol, triacetate;1,2,3-Propanetriol triacetate;acetic acid 1,2,3-propane triyl ester;2-acetyloxy-1-(acetyloxymethyl)ethyl acetate; 2-(acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;captex 500; 1,3-diacetyloxypropan-2-yl acetate; enzactin; fungacetin;glycerin triacetate; glycerol triacetate; glyceryl triacetate;1,2,3-propane triol triacetate; 1,2,3-    propane triyl triacetate propane-1,2,3-triyl triacetate;1,2,3-propanetriol triacetate;1,2,3-propanetriol, triacetate;1,2,3-propanetriyl triacetate;(tri-)acetin;triacetin EP grade;triacetin FCC;triacetin food grade;triacetin regular grade;triacetin synthetic;triacetinUSP;triacetine;1,2,3-triacetoxypropane;triacetyl glycerine;triacetyl glycerol;triacetylglycerol;vanay;1,2,3 propanedioltriacetate;1,2,3-propanedioltriethanoate;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;Acetin, tri-;Enzactin;femanumber2007;Fungacetin;Glycerol triacetate tributyrin;tri asetin; triasetin; tri acetin; triacetin; TRIACETIN; TRI ACETIN;Glyceryl triacetate, 1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glycerol triacetate;Glyceryl triacetate, INS No. 1518 ;ENZACTIN, GLYCERYL TRIACETATE, TRIACETYL GLYCERINE;1,2,3-Propanetriol triacetate; 1,2,3-Propanetriyl triacetate    ;1,2,3-Triacetoxypropane;1,2,3-Triacetylglycerol;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate; Enzactin;Triacetin;Triacetyl glycerol;Triacetyl glycerol;Triacetylglycerol;triacetin;Glycerol triacetate;Glyceryl triacetate;102-76-1;Glycerin triacetate;Enzactin;Triacetine;Triacetylglycerol;Fungacetin;Triacetyl glycerine;Glyped;Vanay;Kesscoflex TRA;Kodaflex triacetin;Acetin, tri-;1,2,3-Propanetriol, triacetate;1,2,3-triacetoxypropane;Triacetinum;Triacetina;1,2,3-Propanetriol triacetate;1,2,3-Triacetylglycerol;1,2,3-Propanetriyl triacetate;FEMA Number 2007;Triacetine [INN-French];Triacetinum [INN-Latin];Triacetina [INN-Spanish];Triacetyl glycerin;NSC 4796;UNII-XHX3C3X673;FEMA No. 2007;HSDB 585;1,2,3-Propanetriol, 1,2,3-triacetate;propane-1,2,3-triyl triacetate;EINECS 203-051-9;1,2,3-triacetyl-glycerol;BRN 1792353;2,3-diacetyloxypropyl acetate;1,2,3-triacetyl-sn-glycerol;AI3-00661;CHEBI:9661;Glycerol triacetate (Triacetin);C9H14O6;URAYPUMNDPQOKB-UHFFFAOYSA-N;Acetic, 1,2,3-propanetriyl ester;MFCD00008716;SBB060703;1,3-bis(acetyloxy)propan-2-yl acetate;NCGC00091612-04;E1518;DSSTox_CID_6691;DSSTox_RID_78184;DSSTox_GSID_26691;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;triacetylglycerin;Triacetyl glycerol;Triacetin [INN];CAS-102-76-1;2-acetyloxy-1-(acetyloxymethyl)ethyl acetate;CCRIS 9355;EOIEyOOEao yen;EOIEy xEao yen;Glycerine triacetate;Triacetin, 99%;TRIACETIN (GLYCEROL TRIACETATE);Spectrum_000881;Triacetin (USP/INN);ENZACTIN (TN); AC1L1KKQ; AC1Q1LBU; Spectrum2_000939; Spectrum3_001368; Spectrum4_000362;Spectrum5_001376;ACMC-1C1GI;Triacetin, >=99.5%;AC1Q1L9A;SCHEMBL3870;BSPBio_002896;KBioGR_000823;KBioSS_001361;4-02-00-00253 (Beilstein Handbook Reference);KSC176O0H;MLS002152946;1,3-Propanetriol, triacetate;DivK1c_000740;Glyceryl triacetate, >=99%;SPECTRUM1500585;Triacetin, analytical standard;SPBio_000878;Triacetin, 99%, FCC, FG; XHX3C3X673; CHEMBL1489254; DTXSID3026691; CTK0H6703;HMS502E22; KBio1_000740;KBio2_001361; KBio2_003929;KBio2_006497;KBio3_002116;EBD5636;NSC4796;MolPort-001-787-791;NINDS_000740;Ey x(3/4)<<; HMS1921G05; HMS2092O09; HMS2232I22; Pharmakon1600-01500585;Glycerol triacetate, 99% 500g;Triacetin USP FCC EP Kosher Tech;HY-B0896;NSC-4796;ZINC1530705;  Tox21_111155;Tox21_201745; Tox21_300111;WLN: 1VO1YOV1 & 1OV1;ANW-14741;CCG 39680;LMGL03012615;NSC757364;ZINC01530705;AKOS009028851;Tox21_111155_1;Glyceryl triacetate, >=99.0% (GC);LS-2356,MCULE-6622854116;NSC-757364;RP27112;RTR-033474;IDI1_000740;NCGC00091612-01;NCGC00091612-02;NCGC00091612-03;NCGC00091612-05;NCGC00091612-06;NCGC00091612-07;NCGC00091612-09;NCGC00254207-01;NCGC00259294-01;CJ-05210;CJ-24005; OR025848; OR195125;OR195126;S168;SMR001224538;SBI-0051540.P002;TR-033474;Triacetin (1,2,3-Propanetriol triacetate);G0086,ST51046833;EN300-19216,D00384;E 1518;AB00052112_06,SR-05000002079;I14-2610;J-000781;SR-05000002079-1;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate #;Z1258578263;Triacetin, GTA F.G (1,2,3-PROPANETRIOL TRIACETATE);Triacetin, United States Pharmacopeia (USP) Reference Standard;Triacetin, pharmaceutical secondary standard; traceable to USP, PhEur;1,2,3-Propanetriol triacetate; 1,2,3-Triacetoxypropane; 1,2,3-Triacetylglycerol; Glycerol triacetate;;InChI=1/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H;acetic acid 1,2,3-propane triyl ester;2-acetyloxy-1-(acetyloxymethyl)ethyl acetate;2-(acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;captex 500;1,3-diacetyloxypropan-2-yl acetate;enzactin;fungacetin;glycerin triacetate;glycerol triacetate;glyceryl triacetate;1,2,3propane triol triacetate;1,2,3-propane triyl triacetate;propane-1,2,3-triyl triacetate;1,2,3-propanetriol triacetate;1,2,3-propanetriol, triacetate;1,2,3-propanetriyl triacetate;(tri-)acetin;triacetin EP grade;triacetin FCC;triacetin regular grade;triacetin synthetic;triacetin USP;triacetine;1,2,3-triacetoxypropane;triacetyl glycerine;triacetyl; glycerol; triacetylglycerol; vanay; Acetin TP LXS; 51035; Glycerinetriacetate; Glyceroltriacetate; Triacetin ,1,2,3-Propanetriol triacetate;1,2,3-Propanetriol, triacetate [ACD/Index Name];1,2,3-Propanetriyl triacetate [ACD/IUPAC Name];1,2,3-Propantriyl-triacetat [German] [ACD/IUPAC Name];1,2,3-Triacetoxypropane;102-76-1 [RN];1VO1YOV1&1OV1 [WLN];203-051-9 [EINECS];glycerol triacetate;Propane-1,2,3-triyl triacetate;Triacétate de 1,2,3-propanetriyle [French] [ACD/IUPAC Name];triacetina [Spanish]; [2-acetoxy-1-(acetoxymethyl)ethyl] acetate;1,2,3-PROPANETRIOL ACETATE;1,2,3-Propanetriol triacetate, 9CI;1,2,3-Propanetriol, 1,2,3-triacetate;1,2,3-triacetylglycerol;1,3-bis(acetyloxy)propan-2-yl acetate;1,3-diacetyloxypropan-2-yl acetate;1,3-diacetyloxypropan-2-yl ethanoate;1792353;2-(acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;2,3-diacetoxypropyl acetate;2,3-diacetyloxypropyl acetate;2-acetyloxy-1-(acetyloxymethyl)ethyl acetate;4-02-00-00253 (Beilstein Handbook Reference) [Beilstein];acetic acid [2-acetoxy-1-(acetoxymethyl)ethyl] ester;Acetic, 1,2,3-propanetriyl ester;Acetin, tri-;Blekin;BSPBio_002896;carbonic acid [4-[[2-[[(4-ethoxycarbonyloxy-3-methoxyphenyl)-oxomethyl]amino]ethylamino]-oxomethyl]-2-methoxyphenyl] ethyl ester;E 1518;E1518;E-1518;EINECS 203-051-9;Enzacetin;ENZACTIN [Trade name];Enzactin (TN);Estol1581;Euzactin;FEMA2007;Fungacet;Fungacetin;Glycerintriacetate;Glycerol triacetate (Triacetin);Glycerol triacetate tributyrin;Glyceryl triacetate;Glyceryl triacetate;Glyceryl triacetate;1,2,3-Triacetoxypropane;Glyped;IDI1_000740;InChI=1/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H;Kesscoflex TRA;Kodaflex triacetin;MFCD00008716 [MDL number];Motisil;NCGC00091612-02;NCGC00091612-03;NCGC00091612-04;Pharmakon1600-01500585;SPECTRUM1500585;Spectrum5_001376;Tri-Acetin;TRIACETIN (GLYCEROL TRIACETATE);Triacetin (USP);Triacetin (usp/inn);Triacetin [inn],Triacetin USP FCC EP Kosher Tech;Triacetin, 8CI, BAN, INN, USAN;Triacetin, GTA F.G (1,2,3-PROPANETRIOL TRIACETATE);triacetin; triacetina; triacetine;triacetinum;Triacetina;Triaceti[INNSpanish];Triacetine;Triacetine [INN-French];Triacetinum;Triacetinum [INN-Latin];Triacetyl glycerin;Triacetyl glycerine;Triacetyl glycerol;triacetylglycerol;UNII:XHX3C3X673;UNII-XHX3C3X673;VANAY;WLN: 1VO1YOV1 & 1OV1;?????? [Chinese];TRI-) ACETIN; 1,2,3-PROPANETRIOL TRIACETATE; 1,2,3-PROPANETRIYL ESTER ACETIC; 1,2,3PROPANETRIOL, TRIACETATE; ACETIC, 1,2,3-PROPANETRIYL ESTER; GLYCERYL TRIACETATE; 1,2,3-PROPANETRIOL TRIACETATE; ENZACTIN; FUNGACETIN; GLYCERIN TRIACETATE; GLYCEROL TRIACETATE;Glycerol triacetate; Glycerol, acetylated; 1,2,3-Propanetriol, triacetate; Acetin, tri-; Enzactin; Fungacetin; Glycerin triacetate; Glyceryl triacetate; Glyped; Kesscoflex TRA; Triacetine; Vanay; Kodaflex triacetin; Triacetyl glycerine; Triacetyl glycerin; Triacetyl glycerol; 1,2,3-Propanetriol, 1,2,3-triacetate; NSC 4796; 2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;1,2,3-propanedioltriacetate;1,2,3-propanedioltriethanoate;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;Acetin, tri-;Enzactin;femanumber2007;Fungacetin;Glycerol triacetate tributyrin;Glyceryl triacetate;Acetic acid 1,2,3-propane triyl ester;1,3-    diacetyloxypropan-2-yl acetate;Enzactin;Fungacetin;Glycerin triacetate;Glycerol triacetate;Glyceryl triacetate;1,2,3-propane triol triacetate;1,2,3-propane triyl triacetate;(tri-)acetin;Triacetine;Triacetyl glycerine;Triacetyl glycerol;Vanay;1,2,3-propanedioltriacetate;1,2,3-propanedioltriethanoate;2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate;Acetin, tri-;Enzactin;femanumber2007;Fungacetin;Glycerol triacetate tributyrin; TRIACETIN DRUM; TRIACETIN; TRİACETİN DRUM; TRİACETİN; Triacétine; La Triacétine;trıacetın;  Triacétine IBC; TRİACETİNE IBC

TRIACETIN IBC

Basic information
Product name: triacetin
Triacetin CAS #: 102-76-1
Molecular formula of triacetin: C9H14O6
Molecular Weight of Triacetin: 218.20400
Other name for triacetin: 1,2,3-propanetriol, triacetate; Glycerol triacetate; Glyped; 2,3-diacetyloxypropyl acetate; 1,2,3-propanetriol triacetate ;; Glyceryl triacetate; Glycerin triacetate; 1,2,3-triacetylglycerol; Enzactin; Glycerol triacetate; Triacetyl glycerin; 1,2,3-triacetoxypropane; Fungacetin; Triacetin; Glycerin triacetate
LogP: 0.2
PSA: 78.90000
Property of triacetin
Clear, colorless oily liquid with a bitter taste, non-toxic, slightly soluble in water, soluble in many kinds of organic solvents. Boiling point: 258 ℃ (0.101mpa), flash point (near) 138 ℃ ， Melting point: 3 ℃ (101.3 KPa).

Use of triacetin
The product is an environmentally friendly plasticizer that does not contain phthalates. It complies with the environmental standards of the European Union, the United States and other developed countries. It is mainly used for cigarette filter tips which is a plasticizer of cellulose diacetate, also used in flavorings, cosmetic fixatives. In addition, it can be used as a plasticizer and as a solvent for printing ink, nitrocellulose, cellulose acetate, ethyecellulose and ellulose acetate butyrate. In casting, it is used as a hardener for casting sand.

TRIACETİNE
triacetin-tech
Widely used as a plasticizer in applications ranging from cigarette filters to chewing gum. Used as a solvent and fixer in the aroma and perfume industry.

Applications of triacetin
Pharmaceutical, Food, Solvent / carrier in aroma and perfumes, Plasticizer - Cigarette filters, Plasticizer - chewing gum base, Adhesives

Triacetin (food / pharmaceutical grade) is also known as:
1,2,3-propanetriol, triacetate, 1,2,3-triacetoxypropane, enzactin, fungacetin, glycerin triacetate, glycerol triacetate, glyceryl triacetate, glycerol, triacetin

Properties
Odor Description: Very low odor
Appearance: Clear, colorless liquid

Triacetin CAS number 102-76-1

Chemical identifiers of triacetin
Triacetin CAS # 102-76-1
Molecular formula of triacetin C9H14O6
Molecular Weight of triacetin (g / mol) 218.21
InChI Key of triacetin URAYPUMNDPQOKB-UHFFFAOYSA-N
Synonym triacetin, glyceryl triacetate, glycerol triacetate, glycerin triacetate, enzactin, triacetine, triacetylglycerol, fungacetin, glyped, triacetyl glycerineShow less
PubChem CID 5541
ChEBI CHEBI: 9661
IUPAC Name 2,3-Diacetyloxypropyl Acetate
SMILES CC (= O) OCC (COC (= O) C) OC (= O) C

Triacetin
Illustrative image of the article Triacetin
Identification
IUPAC name 1,3-diacetyloxypropan-2-yl acetate
Synonyms
Glyceryl triacetate
Glycerin triacetate
1,2,3-Triacetoxypropane
Enzactin

Triacetin CAS RN 102-76-1
ECHA No of Triacetin 100.002.775
Triacetin EC No 203-051-9
PubChem for triacetin 5541 [archive]
E number of triacetin E1518
FEMA 2007

Appearance of colorless, oily liquid triacetin 2.
Chemical properties of triacetin
Crude formula of triacetin C9H14O6 [Isomers]
Molar mass of triacetin3 218.2039 ± 0.01 g / mol
C 49.54%, H 6.47%, O 43.99%,
pKa
pH of triacetin 5 to 6 (50 g l-1)
Physical properties of triacetin
Melting temperature −78 ° C2
Boiling temperature 258 to 260 ° C2
Solubility of triacetin Soluble in water (64 g · l − 1 at 20 ° C),
ethanol, ether and chloroform.
Density of triacetin1.16 gcm-32
Self-ignition temperature of triacetin 433 ° C2
Flash point of triacetin 138 ° C (closed cup) 2
153 ° C (open cup)
Explosive limits in air of triacetin 1.1 - 7.7 Vol%
Saturating vapor pressure at 25 ° C: 0.33 Pa2
Thermochemistry
Cp
[+]
Precautions
NFPA 704
NFPA 704 Symbol

100
Directive 67/548 / EEC
Irritant
Xi
[+]
S-phrases: 23, 24/25,
Ecotoxicology
LD50 1.1 gkg-1 (mouse, oral) 5
1.6 g kg-1 (mouse, i.v.) 5
2.3 g kg-1 (mouse, s.c.) 5
1.4 g kg-1 (mouse, i.p.) 5
1.5 g kg-1 (dog, i.v.)
0.75 g kg-1 (rabbit, i.v.)
Related compounds
Other compounds
acetic acid

SI and CNTP units, unless otherwise indicated.
modify Consult the model documentation
Triacetin or glyceryl triacetate is an artificial compound with multiple applications.

Chemistry
Triacetin is a triester of glycerol and acetic acid. It is the smallest of the triglycerides (acylglycerol) after glyceryl triformate, however it is artificial. This triglyceride is obtained by esterification of natural glycerin or from petrochemicals with acetic anhydride.

Its chemical formula is C9H14O6 and its molar mass is 218.21 g / mol6.

Triacetin is a colorless liquid with an oily consistency with a faint oily, ethereal and fruity odor6.

Uses
Food

triacetin is used as a food additive for its humectant property under the number E15187.

Like propylene glycol and ethanol, it is used in food flavorings as a solvent and excipient (fema-GRAS number 20076). Its last evaluation by JECFA dates from 2002 (Session 59).

Fuel
Triacetin is also used as a fuel adjuvant to reduce knocking and improve the cold resistance and viscosity of biodiesels.

Medicines
Triacetin is an excipient used as a plasticizer in polymer blends used for the film coating of tablets8.

Triacetin has antimycotic activity5. This activity seems to be linked to the gradual release of acetic acid by hydrolysis of triacetin9 by the esterases of the microscopic fungi responsible for mycoses. Triacetin was marketed from 1956 under the trade name of Fungacetin, in the form of an aerosol, a cream or a powder to be applied to the skin10.

Other
Triacetin is also an additive used in processed tobacco for cigarettes, fine cut tobacco, pipe tobacco, snuff, chewing tobacco and cigars11.

In the late 1960s, triacetin was considered a possible source of long-term dietary energy for space missions12, after being tested on rats13.

Triacetin
CAS No: 102-76-1 - Triacetin
 "Good" in all categories.
INCI name: TRIACETIN
Chemical name: Triacetin
EINECS / ELINCS number: 203-051-9
Food additive: E1518
Its functions (INCI)
Antimicrobial: Helps slow the growth of microorganisms on the skin and suppresses the growth of microbes
Film forming agent: Produces a continuous film on the skin, hair or nails
Masking Agent: Reduces or inhibits the basic odor or taste of the product
Plasticizer: Softens and suppresses another substance that otherwise could not be easily deformed, dispersed or worked
Solvent: Dissolves other substances
Triacetin is present in 0.11% of cosmetics.
Foundation (0.79%)

Glycerol triacetate
Inci name
Triacetin
French name
Glycerol triacetate
CAS number.
102-76-1
EC No.
203-051-9
Other appellations
Triacetin
Origins
Vegetable
Synthetic
CosIng functions
Antimicrobial agent
Film-forming agent
Masking agent
Plasticizer
Solvent
Can be used in the composition of perfumes

Triacetin
Regulatory Process Names 2 CAS Names 1 IUPAC Names 5 Trade Names 11 Other Identifiers 2
Print the information cardOpen the short profileRegulatory obligations relating to open substances
Substance identity
Help me
EC No / List: 203-051-9

CAS number: 102-76-1

Mol. formula: C9H14O6

formula
Hazard classification and labeling
Help me
According to the notifications provided by companies to ECHA in REACH registrations, no hazards have been classified.

About this substance
Useful information
This substance is manufactured and / or imported into the European Economic Area at the rate of 10,000 to 100,000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or repackaging, on industrial sites and in manufacturing.

Consumer uses
This substance is used in the following products: adhesives and sealants, perfumes and perfumes, air care products, shoe polishes and waxes, washing and cleaning products, cosmetics and personal care products, biocides (e.g. disinfectants, products pest control), coating products, inks and toners and polymers. Release to the environment of this substance may occur as a result of industrial use: formulation into materials. Further releases to the environment of this substance are likely to occur from: indoor use (for example, machine wash liquids / detergents, automotive care products, paints and coatings or adhesives , perfumes and air fresheners), outdoor use, indoor use long-lasting materials with a low release rate (e.g. flooring, furniture, toys, building materials, curtains, shoes, leather products, paper and cardboard products, electronic equipment), outdoor use in long-lived materials with low release rate (e.g. metal, wood and plastic construction and building materials) and interior use in long-lived materials with a high release rate (eg, release of fabrics, textiles during washing, removal of interior paints).

Article life
Other releases to the environment of this substance are likely to occur from: use n inside long-lived materials with low rejection rates (e.g. flooring, furniture, toys, building materials, curtains, shoes, leather products, paper and cardboard products, electronic equipment), outdoor use in long-lived, low-release materials (e.g. metal, wood and plastic building and construction materials) and indoor use in long-lived materials with high release rate (eg release of fabrics, textiles during washing, removal of interior paints).
This substance can be found in products with materials based on: paper (eg, tissues, feminine hygiene products, diapers, books, magazines, wallpaper), wood (eg, floors, furniture, toys ) and plastic (eg packaging and storage of food, toys, cell phones).
This substance is intended to be released from perfumes: clothing, eraser, toys, paper products and CDs.
Generalized uses by professionals
This substance is used in the following products: washing and cleaning products, adhesives and sealants, polishes and waxes, and cosmetics and personal care products.
This substance is used in the following fields: health services and formulation of mixtures and / or repackaging.
This substance is used in the manufacture of: chemicals.
Further releases to the environment of this substance are likely to occur from: indoor use (for example, machine wash liquids / detergents, automotive care products, paints and coatings or adhesives , perfumes and air fresheners) and outdoors.
Formulation or repackaging
This substance is used in the following products: adhesives and sealants, cosmetics and personal care products, perfumes and fragrances, coatings, inks and toners, pharmaceuticals, washing and cleaning products and polymers.
The release to the environment of this substance may result from industrial use: formulation of mixtures, formulation in materials, manufacture of the substance, as an intermediate step in the subsequent manufacture of another substance (use of intermediates) and as a technological aid.
Uses on industrial sites
This substance is used in the following products: adhesives and sealants, washing and cleaning products, coating products, cosmetics and personal care products, inks and toners, perfumes and fragrances, polymers and air care products.
This substance is used in the following fields: formulation of mixtures and / or repackaging, health services and building and construction work.
This substance is used in the manufacture of: chemicals and furniture.
The release to the environment of this substance may result from industrial use: in the production of articles, in processing aids at industrial sites, the formulation of mixtures, as an intermediate step in the subsequent manufacture of another substance (use of intermediates), substances in closed systems with minimal release systems, as processing aid and manufacture of the substance.
Further releases to the environment of this substance are likely to occur from: indoor use (for example, machine wash liquids / detergents, automotive care products, paints and coatings or adhesives , perfumes and fresh air)

Manufacturing
The release to the environment of this substance may result from industrial use: manufacture of the substance, formulation of mixtures, for thermoplastic manufacture, of substances in closed systems with minimal release, in processing aids at industrial sites , as an intermediate step in the subsequent manufacture of another substance (use of intermediates), as a processing aid and in the production of articles.

Triacetin, also known as glyceryl triacetate, is reported to function as a biocide, plasticizer, and cosmetic solvent in cosmetic formulations, at concentrations ranging from 0.8% to 4.0%. It is a commonly used medium for aromas and fragrances. Triacetin has been recognized as a generally recognized safe human food ingredient (GRAS) by the Food and Drug Administration (FDA). Triacetin was not toxic to animals during acute oral or dermal exposures, in short-term inhalation or parenteral studies, or in subchronic feeding and inhalation studies. The triacetin was, at most, slightly irritating to the skin guinea pig. However, in one study, it caused erythema, slight edema, alopecia and scaling, and caused some irritation in rabbit eyes. Triacetin was not sensitizing in guinea pigs. Triacetin was not an irritant or sensitizer in a clinical maximization study, and only very mild reactions were seen in a Duhring chamber test using 50% dilution. In humans, triacetin is believed to have caused eye irritation but no injury. Triacetin was not mutagenic. Although there are no data available on reproductive and developmental toxicity, triacetin was rapidly metabolized to glycerol and acetic acid and these chemicals were not developmental toxins. Reports of 1,2-glyceryl diesters, which may be present in triacetin, affecting cell growth and proliferation have raised the possibility of hyperplasia and / or tumor promotion. The Cosmetic Ingredients Review (CIR) expert group, however, concluded that the effects of 1,2-glyceryl diesters on cell growth and proliferation require longer ester chains on the glycerin backbone. than those present when acetic acid is esterified with glycerin, as in triacetin. . Based on the information available, the CIR expert group concluded that triacetin is safe when used in cosmetic formulations. 1,2,3-Triacetoxypropane triglyceride is more generally known as triacetin and glycerin triacetate. It is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride. [6] It is a colorless, viscous, odorless liquid with a high boiling point. Triacetin (C9H14O6), also known as glyceryl triacetate, is a pharmaceutical excipient used in the manufacture of capsules and tablets , and has been used as a humectant, plasticizer and solvent. It is a liquid, and has been approved by the FDA as a food additive. Triacetin is a water soluble short chain triglyceride that may also act as a parenteral nutrient according to animal studies. [1] [2] It is also used in the perfume and cosmetic industries. Triacetin is a transparent, colorless acetate ester used to plasticize synthetic rubber and cellulose derivatives. Triacetin is easily soluble in aromatic hydrocarbons and most organic solvents. It is insoluble in aliphatic hydrocarbons, mineral oils, and vegetable and animal oils. It has low solubility in water. Triacetin, also known as enzactin or E1518, belongs to the class of organic compounds called triacylglycerols. They are glycerides made up of three chains of fatty acids covalently linked to a glycerol molecule by ester bonds. Thus, triacetin is considered a lipid molecule of triradylglycerol. Triacetin exists as a liquid, soluble (in water) and an extremely weak basic compound (mostly neutral) (based on its pKa). Triacetin has been found in human adipose tissue and has also been mainly detected in blood. Within the cell, triacetin is mainly localized in the cytoplasm and adiposome. Triacetin can be biosynthesized from acetic acid. Triacetin is a sweet, bitter, and clean tasting compound that can be found in fruits and papaya. This makes triacetin a potential biomarker for the consumption of these food products.

Uses

It is an artificial chemical compound, commonly used as a food additive, for example as a solvent in flavors, and for its moisturizing function, with the number E E1518 and the Australian approval code A1518. It is used as an excipient in pharmaceuticals, where it is used as a humectant, plasticizer and as a solvent. Triacetin can also be used as a fuel additive as an anti-knock agent that can reduce engine knock in gasoline and improve the cold and viscosity properties of biodiesel. In a 1994 report published by five major cigarette companies , triacetin was among the 599 additives for cigarettes. Triacetin is applied to the filter as a plasticizer and has been seen as a possible source of food energy in artificial food regeneration systems during long space missions. It is believed to be safe to get more than half of the dietary energy of triacetin.

Triacetin and two types of acetooleins have been shown to have no  toxic effects in long-term rat feeding tests at levels several orders of magnitude higher than those to which consumers are exposed. Three types of acetostearins were found to have no toxic effects in long-term feeding tests in rats at levels up to 5g per kg per day. This contrasts with human consumption estimated at a fraction of a milligram per kg per day. Triacetin ibc is recognized that at an even higher feed level (10g per kg per day), male rats developed testicular atrophy and female rats developed uterine discoloration. However, such a level which would amount to 50 g or more for an infant and 600 g for an adult per day, is considerably higher than what would be possible in the consumption of foods to which acetostearins are added for functional purposes.