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Triacetin is a colorless, oily liquid of slight fatty odor and bitter taste. Triacetin is soluble with water and is miscible with alcohol and ether. Triacetin functions in foods as a humectant and solvent.
CAS NO: 102-76-1
IUPAC NAME:
1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glyceryl triacetate; ; 1,3-bis(acetyloxy)propan-2-yl acetate; 1,3-diacetyloxypropan-2-yl acetate; 2,3-diacetyloxypropyl acetate; propane-1,2,3-triyl triacetate; Triacetin; triacetin
TRADE NAME:
1,2,3-Propanetriol triacetate; acetine tp lxs 51035; Edenor GTA; Glyceryl triacetate; Palmester; TRIACETIN; Triacetin; triacetin; Triacetin FCC; Triacetin H; Triacetin P; Triacetin PH EP; Triacetin PH USP; Triacetin S
OTHER NAME:
102-76-1; 2102168-03-4
SYNONYM :
Triacetin; Glyceryl triacetate; 102-76-1; Glycerol triacetate; Glycerin triacetate; Enzactin; Triacetine UNII-XHX3C3X673; FEMA No. 2007; HSDB 585; Triacetin (USP/INN); Acetic, 1,2,3-propanetriyl ester; ENZACTIN (TN); EINECS 203-051-9; 1,2,3-triacetyl-glycerol; TRIACETIN (GLYCEROL TRIACETATE); 2-(Acetyloxy)-1- [(acetyloxy)methyl] ethyl acetate; BRN 1792353; 2,3-diacetyloxypropyl acetate; Spectrum2_000939; Spectrum3_001368; Spectrum4_000362; Spectrum5_001376; CMC-1C1GI; D0Q6DX; EC 203-051-9; Triacetin, >=99.5%; AC1Q1L9A; SCHEMBL3870; BSPBio_002896; Glycerol triacetate tributyrin; KBioGR_000823; KBioSS_001361; 4-02-00-00253; KSC176O0H; MLS002152946; 1,3-Propanetriol, triacetate; DivK1c_000740; Glyceryl triacetate, >=99%; SPECTRUM1500585; Triacetin, analytical standard; SPBio_000878; Triacetin, 99%, FCC, FG; CHEMBL1489254; DTXSID3026691; CTK0H6703; FEMA 2007; HMS502E22; KBio1_000740; KBio2_001361; KBio2_003929; KBio2_006497; KBio3_002116; KS-00000YQB
Under suitable conditions, Triacetin can be stored for one year. Triacetin can be stored in a stainless steel tank. Triacetin is readily soluble in aromatic hydrocarbons and most organic solvents. Triacetin is insoluble in aliphatic hydrocarbons, mineral oils, and vegetable and animal oils. Solubility in water is low.
Triacetin is used for the solidification of acetyl cellulose fibres in the manufacture of cigarette filters. The water content must be kept constant to achieve constant solidification. Triacetin is also used as a support for flavourings and essences in the food industry and as a plasticiser for chewing gum. In technical applications, Triacetin is used for example as a core sand binder in the metal foundry sector. Another application is inks and printing inks. Triacetin is used as a highlyeffective plasticiser for cellulose-based plastics.
Triacetin is water transparent, odorless liquid. Triacetin is low viscosity, miscible with organic solvents. It is insoluble in water and vegetable oils. It should be stored in a dry and cool place (max. 30 oC). Triacetin does not lose its properties for 12 months in its original package. Triacetin is used as a solvent and plasticizer.
Triacetin is used in perfumery, tanning, food additives, as a gelatinizing agent, explosives, cosmetics and external medicine. Tiacetin is used as an ingredient in many food and cosmetic products. Its strong solubility and low volatility make it a good solvent and fixative for many flavors and essences. It is a solvent aid in oleoresins, especially in alcohol-free concentrates. One of its most important uses is as a plasticizer in a chewing gum. Triacetin is plasticizer and water binder in cigarette films.
Food grade triacetin; Triacetin is used in animal foods, sweeteners, food grade plasticizer, moisture retainer, color cosmetics / skin care products, as a food additive, food packaging and as a solvent. Triacetin has been considered safe for use in human and animal foods. Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
Triacetin has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. Triacetin has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug. Triacetin derives from an acetic acid. Triacetin can be mixed with ethanol, ether, benzene, chloroform and other organic solvents, soluble in acetone, insoluble in mineral oil. Slightly soluble in water. 5.9 g / 100 ml water solubility at 25 ° C.
Triacetin is a water-transparent, odorless liquid. Triacetin is low viscosity, miscible with organic solvents. Triacetin is insoluble in water and vegetable oils. Triacetin should be stored in a dry and cool place (max. 30 oC). It does not lose its properties for 12 months in its original package. Triacetin is used as a solvent and plasticizer. Triacetin is used in perfumery, tanning, food additives, as a gelatinizing agent, explosives, cosmetics and external medicine.
Tiacetin is used as an ingredient in many food and cosmetic products. Its strong solubility and low volatility make it a good solvent and fixative for many flavors and essences. Triacetin is a solvent aid in oleoresins, especially in alcohol-free concentrates. One of its most important uses is as a plasticizer in a chewing gum. Triacetin is plasticizer and water binder in cigarette films. Food grade triacetin; as food additive in animal foods, sweeteners, food grade plasticizer, moisture retainer, color cosmetics / skin care products,
Triacetin is used in food packaging and as a solvent. Triacetin has been considered safe for use in human and animal foods. Triacetin is an aromatic chemical compound commonly used as a food additive. For example, Triacetin is used as a solvent and moisturizer in sweeteners. Triacetin is also used as moisture retainer, plasticizer and solvent auxiliary in pharmaceutical products.
Triacetin is used as an ingredient in many food and cosmetic products. Its high solubility and low volatility make triacetin a good solvent and stabilizer for many flavors and odors. One of its main uses is in chewing gum as a plasticizer. The United States Food and Drug Administration has confirmed that triacetin is generally considered safe for use in human food.
Triacetin is also considered safe for use in animal feed, as an insecticide and in food packaging. Triacetin can also be used as an anti-knock agent in gasoline, which reduces engine kick and improves the cold and viscosity properties of biodiesel.
The triglyceride 1, 2, 3-triacetoxypropane is more generally known as triacetin and glycerin triacetate. Triacetin is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride. Triacetin is a colorless, viscous and odorless liquid with a high boiling point. Triacetin (glyceryl triacetate) is used as an ingredient in many food and cosmetic products. Its high solvency power and low volatility make triacetin a good solvent and fixative for many flavors and fragrances.
One of its main uses is as a plasticizer in chewing gum. The United States Food and Drug Administration affirmed triacetin as generally recognized as safe (GRAS) for use in human food. Triacetin is also generally recognized as safe in animal feeds, as a pesticide adjuvant, and in food packaging. Triacetin is a triester of glycerin and acetic acid.
Triacetin has been used for over 75 years for a wide range of uses, including cosmetic biocide (most often as a fungicide), plasticizer, solvent in cosmetic formulas, food additive (as a flavoring agent and adjuvant), and as a binder for combustible material in solid-rocket propellants.
Triacetin is also known as glyceryl triacetate, glycerol triacetate, glycerin triacetate, glycerine triacetate, triacetyl glycerine, acetin-tri, 1,2,3-triacetoxypropane, 1,2,3-propanetriol triacetate, 1,2,3-propanetriyl triacetate, and acetic-1,2,3-prepanetriyl ester. Common trade names include Enzactin, Fungacetin, Glyped, Kesscoflex TRA, and Vanay. It is a colorless, oily liquid that, although is most often synthesized, can be found naturally in cod-liver oil, butter, and other fats.
Reflecting its chemical nature and its widespread use as a Food and Drug Administration generally recognized as safe food additive, there is no U.S. Environmental Protection Agency Integrated Risk Information System record on triacetin, and no threshold limit values have been established to protect occupationally exposed workers to the compound. The only limitation on triacetin is Good Manufacturing Practice (GMP) requirements set by the FDA.
The potential environmental effects of triacetin are of particular interest because Triacetin is a high production volume chemical. Japan, the leading producer of triacetin, was estimated to produce 5,000 tons per year, compared to the global production of about 10,000 to 50,000 t/yr.
One Japanese production site that produced 2,000 t/yr was estimated to release about 1,440 kilograms per year (kg/yr) through wastewater. In the United States, Shackelford and Keith detected triacetin in samples collected from the Tennessee River, but no concentration levels were reported. Triacetin is a colorless, oily liquid of slight fatty odor and bitter taste. Triacetin is soluble with water and is miscible with alcohol and ether.
Triacetin functions in foods as a humectant and solvent. Triacetin is prepared by the esterification of glycerin with acetic anhydride. Triacetin is mainly used as a hydrophilic plasticizer in both aqueous and solvent-based polymeric coating of capsules, tablets, beads, and granules; typical concentrations used are 10–35% w/w. Triacetin is used in cosmetics, perfumery, and foods as a solvent and as a fixative in the formulation of perfumes and flavors.
Triacetin is a component of cigarette filters, which induced a contact dermatitis in a worker at a cigarette manufactory. Triacetin is an artificial chemical compound, commonly used as a food additive, for example as a solvent in flavors, and for its moisturizing function, with the number E E1518 and the Australian approval code A1518.
Triacetin is used as an excipient in pharmaceuticals, where Triacetin is used as a humectant, plasticizer and as a solvent. Triacetin can also be used as a fuel additive as an anti-knock agent that can reduce engine knock in gasoline and improve the cold and viscosity properties of biodiesel.
In a 1994 report published by five major cigarette companies , triacetin was among the 599 additives for cigarettes. Triacetin is applied to the filter as a plasticizer and has been seen as a possible source of food energy in artificial food regeneration systems during long space missions. Triacetin is believed to be safe to get more than half of the dietary energy of triacetin.
Triacetin and two types of acetooleins have been shown to have no toxic effects in long-term rat feeding tests at levels several orders of magnitude higher than those to which consumers are exposed. Three types of acetostearins were found to have no toxic effects in long-term feeding tests in rats at levels up to 5g per kg per day.
This contrasts with human consumption estimated at a fraction of a milligram per kg per day. Triacetin ibc is recognized that at an even higher feed level (10g per kg per day), male rats developed testicular atrophy and female rats developed uterine discoloration. However, such a level which would amount to 50 g or more for an infant and 600 g for an adult per day, is considerably higher than what would be possible in the consumption of foods to which acetostearins are added for functional purposes.
Triacetin can be derived from the esterification of glycerol and acetic acid. After preheating glycerol to 50-60 ° C, add acetic acid, benzene and sulfuric acid. Heat and stir for refluxing dehydration, and recycle the benzene. Then add acetic anhydride for heating of 4h. After cooling, the mixture was neutralized with 5% sodium carbonate to pH 7, and the crude layer was dried and the crude oil was dried with calcium chloride.
Distill under reduced pressure, collect the 128-131 ° C (0.93 kPa) fraction, namely glycerol triacetate. Triacetin (C8H14O6), also known as 1,2,3-propanetriol triacetate or glyceryl triacetate, is the triester of glycerin and acetic acid. Triacetin can be prepared by heating glycerin with acetic anhydride alone or in the presence of finely divided potassium hydrogen sulfate. Triacetin can also be prepared by the reaction of oxygen with a liquid-phase mixture of allyl acetate and acetic acid using a bromide salt as a catalyst. Triacetin has a very faint, fruity odor.
Triacetin has a mild, sweet taste that is bitter above 0.05%. Triacetin, a component of cigarette filters, induced a contact dermatitis in a worker at a cigarette manufacturers. Triacetin is prepared by the esterification of glycerin with acetic anhydride. Triacetin is stable and should be stored in a well-closed, nonmetallic container, in a cool, dry place.
Triacetin is incompatible with metals and may react with oxidizing agents. Triacetin may destroy rayon fabric. Triacetin (triacetin) is an aromatic chemical compound commonly used as a food additive. For example, it is used as a solvent and moisturizer in sweeteners. It is also used as moisture retainer, plasticizer and solvent auxiliary in pharmaceutical products.
Triacetin (triacetin) (glyceryl triacetate) is used as an ingredient in many food and cosmetic products. Its high solubility and low volatility make triacetin a good solvent and stabilizer for many flavors and odors. One of its main uses is in chewing gum as a plasticizer. The United States Food and Drug Administration has confirmed that triacetin is generally considered safe (GRAS) for use in human food.
Triacetin is also considered safe for use in animal feed, as an insecticide and in food packaging. Triacetin can also be used as an anti-knock agent in gasoline that reduces engine kick and improves the cold and viscosity properties of biodiesel. Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. Triacetin has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug. Triacetin derives from an acetic acid.
