TRICALCIUM PHOSPHATE

Tricalcium Phosphate is a calcium phosphate salt widely used in food, nutrition, pharmaceutical, and industrial applications as an anti-caking agent, carrier, and calcium and phosphorus source.
Tricalcium Phosphate is commonly identified as E341(iii) in food applications, and Tricalcium Phosphate is valued for very low water solubility, powder flow improvement, and good stability in dry systems.
Tricalcium Phosphate can also be used for calcium fortification, but Tricalcium Phosphate particle size and formulation design must be controlled to manage sedimentation and mouthfeel in sensitive products.

CAS Number: 7758-87-4
EC Number: 231-840-8
Molecular Formula: Ca3(PO4)2
Molecular Weight: 310.18 g/mol

Synonyms: Tricalcium Phosphate, TCP, Tribasic Calcium Phosphate, Calcium Orthophosphate, Calcium Phosphate Tribasic, E341(iii), E341 Tricalcium Phosphate, Tricalcium Phosphate Food Grade, Tricalcium Phosphate Anti-Caking Agent, Tricalcium Phosphate Carrier, Tricalcium Phosphate Calcium Fortifier, Calcium Phosphate E341, Tricalcium Phosphate, TRICALCIUM PHOSPHATE, Tricalcium phosphate, TCP, TCP (Tricalcium Phosphate), Calcium Phosphate Tribasic, Calcium phosphate tribasic, Tribasic Calcium Phosphate, Tribasic calcium phosphate, Calcium Orthophosphate (tribasic), Calcium orthophosphate (tribasic), Tricalcium Orthophosphate, Tricalcium orthophosphate, Orthophosphoric Acid Tricalcium Salt, Tricalcium Salt of Phosphoric Acid, Phosphoric Acid Tricalcium Salt, Calcium Phosphate, Tribasic, Calcium phosphate, tribasic, Ca3(PO4)2, Ca₃(PO₄)₂, E341(iii), E341 (iii), E341iii, E 341(iii), INS 341(iii), Tricalcium Phosphate (E341), Tricalcium Phosphate (E341iii), Tricalcium phosphate (E341) (food additive), Tricalcium phosphate (anti-caking agent), Tricalcium phosphate (flow agent), Tricalcium phosphate (acidity regulator), Tricalcium phosphate (stabilizer), Tricalcium phosphate (mineral supplement) (use context), Tricalcium phosphate powder, Tricalcium phosphate fine powder, Tricalcium phosphate granules, Tricalcium phosphate precipitated, Precipitated tricalcium phosphate

APPLICATIONS

Tricalcium Phosphate is used as an anti-caking agent in powdered foods to improve flow and reduce clumping during storage.
Tricalcium Phosphate is incorporated into seasoning blends to keep powders free-flowing under humid conditions.
Tricalcium Phosphate is used in powdered soup mixes to reduce caking and improve dosing consistency.

Tricalcium Phosphate is used in powdered beverage mixes to improve bulk handling and reduce lump formation.
Tricalcium Phosphate is incorporated into coffee and cocoa drink powders to maintain flow and reduce moisture sensitivity.
Tricalcium Phosphate is used in milk-based drink powders to reduce clumping during storage.

Tricalcium Phosphate is used in salt and spice shakers to reduce clumping and ensure consistent dispensing.
Tricalcium Phosphate is incorporated into powdered sugar products to improve flow and reduce caking.
Tricalcium Phosphate is used in flavor seasoning packets to reduce bridging and maintain consistent dosing.

Tricalcium Phosphate is used as a carrier for flavors, colors, and low-dose actives to improve uniform distribution in dry mixes.
Tricalcium Phosphate is incorporated into vitamin and mineral premixes to improve flow and reduce segregation.
Tricalcium Phosphate is used in food premix manufacturing to improve blending efficiency and handling.

Tricalcium Phosphate is used as a calcium fortifier in cereals and snack powders to increase calcium content with minimal taste impact.
Tricalcium Phosphate is incorporated into nutrition bars and dry blends to deliver calcium and phosphorus in stable form.
Tricalcium Phosphate is used in fortified flour and bakery premixes to support mineral enrichment programs.

Tricalcium Phosphate is used in infant and medical nutrition powders as a calcium and phosphorus source in controlled formulations.
Tricalcium Phosphate is incorporated into meal replacement powders to support mineral fortification and blend stability.
Tricalcium Phosphate is used in sports nutrition powders to improve flow and reduce caking in high-protein blends.

Tricalcium Phosphate is used in confectionery powders to improve flow and reduce stickiness during dry handling.
Tricalcium Phosphate is incorporated into chewing gum base processing as a filler and processing aid in approved applications.
Tricalcium Phosphate is used in tablet-like confectionery to improve compressibility and reduce sticking in tooling.

Tricalcium Phosphate is used in pharmaceuticals as an excipient and diluent to improve powder flow and tablet compression.
Tricalcium Phosphate is incorporated into tablet blends to reduce sticking and improve die filling consistency.
Tricalcium Phosphate is used in capsule fills to improve flowability and uniformity of mineral blends.

Tricalcium Phosphate is used in toothpaste as a mild abrasive and polishing agent in some formulations.
Tricalcium Phosphate is incorporated into oral care powders to provide gentle cleaning and calcium source positioning.
Tricalcium Phosphate is used in dental products where mineral-based abrasives are desired.

Tricalcium Phosphate is used in animal nutrition as a mineral supplement to provide calcium and phosphorus in feed formulations.
Tricalcium Phosphate is incorporated into premixes for livestock and poultry to support bone development and nutrition.
Tricalcium Phosphate is used in aquaculture feeds to provide mineral supplementation in compatible systems.

Tricalcium Phosphate is valued because Tricalcium Phosphate improves powder flow and provides stable calcium and phosphorus fortification while remaining low-reactive in many dry systems.
Tricalcium Phosphate is used as an anti-caking agent in powdered foods.
Tricalcium Phosphate helps keep dry blends free-flowing and reduces clumping during storage.
Tricalcium Phosphate supports consistent dosing in manufacturing and consumer use.

Tricalcium Phosphate is used in table salt and seasoning blends to prevent caking.
Tricalcium Phosphate helps reduce moisture-driven bridging in shaker and pouch products.
Tricalcium Phosphate supports stable flow and uniform sprinkle behavior.

Tricalcium Phosphate is used in powdered spices and spice mixes to improve powder flow.
Tricalcium Phosphate helps prevent lump formation in hygroscopic seasoning systems.
Tricalcium Phosphate supports better blending and packaging efficiency in spice production.

Tricalcium Phosphate is used in powdered beverage mixes to improve scoopability and reduce compaction.
Tricalcium Phosphate helps reduce caking in protein powders, meal replacements, and drink mixes.
Tricalcium Phosphate supports more uniform reconstitution by reducing clumps.

Tricalcium Phosphate is used in instant soups and sauce powders to reduce lumping and improve handling.
Tricalcium Phosphate supports better flow in manufacturing hoppers and fillers.
Tricalcium Phosphate helps improve consumer mixing by reducing powder clumps.

Tricalcium Phosphate is used in coffee creamers and powdered whiteners to prevent caking.
Tricalcium Phosphate helps keep powders loose in humid environments.
Tricalcium Phosphate supports consistent spooning and dispersion in hot drinks.

Tricalcium Phosphate is used in cocoa powders and chocolate drink mixes to reduce caking.
Tricalcium Phosphate helps reduce moisture pickup and powder bridging.
Tricalcium Phosphate supports easier mixing and better dispersion in beverages.

Tricalcium Phosphate is used in powdered sugar and icing mixes to improve free-flow.
Tricalcium Phosphate helps reduce clumping of fine sugar powders.
Tricalcium Phosphate supports improved dosing accuracy in industrial baking.

Tricalcium Phosphate is used in dry nutritional blends and infant nutrition powders as a flow aid where permitted.
Tricalcium Phosphate supports stable powder flow and consistent nutrient distribution.
Tricalcium Phosphate helps maintain manufacturing efficiency in sensitive powder products.

Tricalcium Phosphate is used as a calcium fortificant in foods and beverages.
Tricalcium Phosphate supports calcium enrichment in cereals, bars, and nutrition drinks.
Tricalcium Phosphate helps improve nutritional labeling with minimal taste impact.

Tricalcium Phosphate is used in breakfast cereals to provide calcium fortification.
Tricalcium Phosphate supports stable calcium content through extrusion and drying.
Tricalcium Phosphate helps maintain batch-to-batch nutrient consistency.

Tricalcium Phosphate is used in nutritional bars and functional foods to add calcium and phosphate.
Tricalcium Phosphate supports mineral fortification with good processing stability.
Tricalcium Phosphate helps increase nutrient density without strong sensory impact.

Tricalcium Phosphate is used in plant-based beverages as a calcium source in some formulations.
Tricalcium Phosphate supports fortification of plant milks and vegan shakes.
Tricalcium Phosphate helps improve nutritional equivalence claims versus dairy.

Tricalcium Phosphate is used in powdered drink mixes to deliver calcium fortification.
Tricalcium Phosphate supports calcium claims in sports nutrition powders.
Tricalcium Phosphate helps provide mineral stability during shelf life.

Tricalcium Phosphate is used in dietary supplements as a calcium source.
Tricalcium Phosphate supports calcium tablets, capsules, and chewables.
Tricalcium Phosphate helps provide high calcium loading with stable handling properties.

Tricalcium Phosphate is used as a tableting excipient to improve flow and compression.
Tricalcium Phosphate supports direct compression as a filler and binder.
Tricalcium Phosphate helps reduce sticking and improves tablet hardness in manufacturing.

Tricalcium Phosphate is used in chewable tablets to improve texture and reduce tackiness.
Tricalcium Phosphate supports pleasant mouthfeel in mineral and multivitamin chewables.
Tricalcium Phosphate helps improve hardness while maintaining chewability.

Tricalcium Phosphate is used in toothpaste as a mild abrasive and polishing mineral in some formulations.
Tricalcium Phosphate supports cleaning of tooth surfaces and stain removal.
Tricalcium Phosphate helps improve whitening perception through polishing.

Tricalcium Phosphate is used in tooth powders and dry toothpaste tablets as an abrasive base.
Tricalcium Phosphate supports gentle cleaning in powder oral care products.
Tricalcium Phosphate helps improve flow and dosing of oral care powders.

Tricalcium Phosphate is used in dental care research to support remineralization and sensitivity reduction concepts.
Tricalcium Phosphate supports calcium and phosphate delivery to enamel in experimental systems.
Tricalcium Phosphate helps evaluate tooth repair technologies in oral care R&D.

Tricalcium Phosphate is used in pet food as a mineral supplement.
Tricalcium Phosphate supports calcium and phosphorus nutrition in formulated pet diets.
Tricalcium Phosphate helps maintain mineral balance in dog and cat food.

Tricalcium Phosphate is used in animal feed as a calcium and phosphorus source.
Tricalcium Phosphate supports bone development and metabolic needs in livestock.
Tricalcium Phosphate helps improve ration mineral profile in balanced feeding programs.

Tricalcium Phosphate is used in pharmaceutical manufacturing as an excipient and calcium source in some formulations.
Tricalcium Phosphate supports stable filler function in tablets and capsules.
Tricalcium Phosphate helps reduce segregation by improving powder flow in blends.

Tricalcium Phosphate is used in food processing as a processing aid to improve powder handling in plants.
Tricalcium Phosphate supports reduced bridging in silos and hoppers.
Tricalcium Phosphate helps improve packaging efficiency by reducing flow interruptions.

Tricalcium Phosphate is used in biomedical materials research as a calcium phosphate component in bioceramics.
Tricalcium Phosphate supports bone graft substitute development and osteoconductive composites.
Tricalcium Phosphate helps provide mineral phase similar to bone in biomaterial studies.

Tricalcium Phosphate is used in tissue engineering scaffolds as a ceramic filler to improve osteoconductivity.
Tricalcium Phosphate supports polymer–ceramic composite scaffolds designed for bone repair.
Tricalcium Phosphate helps improve stiffness and bioactivity in experimental scaffolds.

Tricalcium Phosphate is used in 3D printing of bioceramic parts in research and prototype manufacturing.
Tricalcium Phosphate supports printable pastes and slurries for porous bone-like structures.
Tricalcium Phosphate helps form ceramic constructs after drying and sintering.

Tricalcium Phosphate is used in ceramics and glass as a phosphate source in specialty formulations.
Tricalcium Phosphate supports controlled phosphate addition in ceramic bodies.
Tricalcium Phosphate helps tune melting and microstructure in niche ceramic research.

Tricalcium Phosphate is used in fertilizer and soil research as a phosphate mineral source.
Tricalcium Phosphate supports studies of phosphorus availability under different soil pH.
Tricalcium Phosphate helps model slow-release phosphate behavior in soil chemistry.

Tricalcium Phosphate is used in laboratory education to demonstrate calcium phosphate solubility and precipitation chemistry.
Tricalcium Phosphate supports experiments on solubility product and pH effects.
Tricalcium Phosphate helps illustrate mineral chemistry relevant to bones and teeth.

DESCRIPTION

Tricalcium Phosphate is a white, fine powder with very low water solubility, and this low solubility supports Tricalcium Phosphate use as an anti-caking agent and inert carrier in dry blends.
Tricalcium Phosphate reduces caking by separating particles and reducing moisture-driven bridging in hygroscopic powders.
Tricalcium Phosphate is produced in food and pharma grades with controlled purity and particle size, and these parameters strongly influence performance and sensory properties.

Tricalcium Phosphate can provide calcium fortification, but Tricalcium Phosphate may settle in liquid systems, so Tricalcium Phosphate is most suitable for dry foods or for liquids that include stabilizers and controlled particle size.
Tricalcium Phosphate can dissolve more under acidic conditions, so strong acids and chelating agents can affect Tricalcium Phosphate stability and solubility in some formulations.
Tricalcium Phosphate should be stored in tightly closed containers in a cool, dry place to prevent moisture uptake and caking.

Tricalcium Phosphate dust can be generated during handling, so dust control and appropriate PPE are recommended.
Tricalcium Phosphate should be used according to applicable regulations and specifications for the intended market and product category.
Tricalcium Phosphate should be handled with good hygiene practices and kept protected from contamination during storage and transfer.

Tricalcium Phosphate is a calcium phosphate salt commonly represented as Ca3(PO4)2.
Tricalcium Phosphate is typically a white, odorless powder with very low taste impact.
Tricalcium Phosphate is widely used as an anti-caking agent and calcium fortificant in dry foods.

Tricalcium Phosphate has very low solubility in water, so it functions mainly as an insoluble mineral additive.
Tricalcium Phosphate can react slowly under acidic conditions, releasing calcium and phosphate ions.
Tricalcium Phosphate therefore provides buffering and mineral availability behavior depending on pH.

Tricalcium Phosphate improves powder flow by reducing moisture-driven bridging and clumping.
Tricalcium Phosphate performance depends on particle size, surface area, and dosage in the powder system.
Tricalcium Phosphate can also act as a carrier for flavors or vitamins in some dry mixes.

Tricalcium Phosphate is used in supplements and pharmaceuticals as a stable calcium source and excipient.
Tricalcium Phosphate supports direct compression due to good flow and compactibility in suitable grades.
Tricalcium Phosphate is also used in toothpaste as a mild abrasive and polishing mineral.

Tricalcium Phosphate quality specifications vary by food, pharma, and technical grades.
Tricalcium Phosphate specifications commonly control heavy metals, fluoride, insoluble matter, and particle properties.
Tricalcium Phosphate should be stored in tightly closed containers to protect against contamination and moisture.

PROPERTIES

Chemical Formula: Ca3(PO4)2
Molecular Weight: 310.18 g/mol
Common Name: Tricalcium Phosphate
Chemical Type: Calcium phosphate salt; anti-caking agent; carrier; mineral source
Appearance: White powder (grade dependent)
Odor: Odorless
Solubility: Very low solubility in water; increased solubility under acidic conditions (system dependent)
Function: Anti-caking agent, carrier, excipient, calcium and phosphorus source
Particle Size: Grade dependent; influences flow, abrasivity, and beverage sedimentation
Bulk Density: Grade dependent; influenced by milling and granulation
Stability: Stable under dry storage; moisture exposure can cause caking and performance drift
Storage Temperature: 15–25°C, dry, tightly closed
Shelf Life: Typically 24–48 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during handling and powder transfer.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses, and use dust protection as needed.
Avoid generating dust and avoid inhalation of fine powder.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use local exhaust or general ventilation where dust may be generated.
Maintain good airflow during weighing, charging, and blending operations.
Minimize airborne particulate accumulation in enclosed areas.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain free-flowing behavior.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Sweep up spilled material and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with wet wiping if needed to reduce airborne dust.

Handling Precautions:
Select the appropriate grade and particle size for the target application to balance anti-caking performance, mouthfeel, and dispersion behavior.
Validate stability in fortified systems because acids, chelants, and proteins can influence Tricalcium Phosphate behavior.
Rotate stock using FIFO practices to maintain consistent quality and predictable processing performance.