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TCS = TRICLOSAN
CAS NO:3380-34-5
EC NO:222-182-2
Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments.
Triclosan is similar in its uses and mechanism of action to triclocarban.
Triclosans efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.
Triclosan was developed in the 1960s. A 2006 study recommended showering with 2% triclosan as a regimen in surgical units to rid patients' skin of methicillin-resistant Staphylococcus aureus (MRSA). While finding benefit for consumers and no proven risk to human health, but assumed risk of antibiotic resistance, in December 2017, the FDA announced that "consumer antiseptic washes" containing triclosan or 23 other ingredients marketed as antimicrobials were prohibited without pre-market approval.The FDA did find that triclosan in Colgate Total toothpaste helped prevent gingivitis.
Properties
Chemical formula C12H7Cl3O2
Molar mass 289.54 g·mol−1
Appearance White solid
Density 1.49 g/cm3
Melting point 55–57 °C (131–135 °F; 328–330 K)
Boiling point 120 °C (248 °F; 393 K)
Uses
Triclosan was used as a hospital scrub in the 1970s. Since then, it has expanded commercially and is now a common ingredient in soaps (0.10–1.00%), shampoos, deodorants, toothpastes, mouthwashes, cleaning supplies, and pesticides.
It is part of consumer products, including kitchen utensils, toys, bedding, socks, and trash bags.
As of 2017, there were five registrations[further explanation needed] for triclosan with the EPA. The antimicrobial active ingredient is added to a variety of products where it acts to slow or stop the growth of bacteria, fungi, and mildew. In commercial, institutional, and industrial equipment uses, triclosan is incorporated in conveyor belts, fire hoses, dye bath vats, or ice-making equipment as an antimicrobial. Triclosan may be directly applied to commercial HVAC coils, where it prevents microbial growth that contributes to product degradation.
In the United States, by 2000, triclosan and triclocarban (TCC) could be found in 75% of liquid soaps and 29% of bar soaps, and as of 2014 triclosan was used in more than 2,000 consumer products.
In healthcare, triclosan is used in surgical scrubs and hand washes.Use in surgical units is effective with a minimum contact time of approximately two minutes. More recently,[when?] showering with 2% triclosan has become a recommended regimen in surgical units for the decolonization of patients whose skin carries methicillin-resistant Staphylococcus aureus (MRSA). Two small uncontrolled case studies reported the use of triclosan correlated with reduction in MRSA infections.
Triclosan is also used in the coatings for some surgical sutures.There is good evidence these triclosan coated sutures reduce the risk of surgical site infection. The World Health Organization, the American College of Surgeons and the Surgical Infection Society point out the benefit of triclosan-coated sutures in reducing the risk for surgical site infection.
Triclosan has been employed as a selective agent in molecular cloning. A bacterial host transformed by a plasmid harboring a triclosan-resistant mutant FabI gene (mFabI) as a selectable marker can grow in presence of high dose of triclosan in growth media.
Chemical structure and properties
This organic compound is a white powdered solid with a slight aromatic, phenolic odor. Categorized as a polychloro phenoxy phenol, triclosan is a chlorinated aromatic compound that has functional groups representative of both ethers and phenols. Phenols often demonstrate antibacterial properties.
Triclosan is soluble in ethanol, methanol, diethyl ether, and strongly basic solutions such as a 1M sodium hydroxide solution, but only slightly soluble in water.
Triclosan can be synthesized from 2,4-dichlorophenol.
Synthesis
Under a reflux process, 2,4,4'-trichloro-2'-methoxydiphenyl ether is treated with aluminium chloride.
The United States Pharmacopeia formulary has published a monograph for triclosan that sets purity standards.
Mechanism of action
At high concentrations, triclosan acts as a biocide with multiple cytoplasmic and membrane targets. However, at the lower concentrations seen in commercial products, triclosan appears bacteriostatic, and it targets bacteria primarily by inhibiting fatty acid synthesis.
Triclosan binds to bacterial enoyl-acyl carrier protein reductase (ENR) enzyme, which is encoded by the gene fabI. This binding increases the enzyme's affinity for nicotinamide adenine dinucleotide (NAD+). This results in the formation of a stable, ternary complex of ENR-NAD+-triclosan, which is unable to participate in fatty acid synthesis. Fatty acids are necessary for building and reproducing cell membranes. Humans do not have an ENR enzyme and thus are not affected by this mode of action.
Endocrine disruptor
Triclosan has been found to be a weak endocrine disruptor, though the relevance of this to humans is uncertain.The compound has been found to bind with low affinity to both the androgen receptor and the estrogen receptor, where both agonistic and antagonistic responses have been observed.
Efflux pump inducer
Triclosan may upregulate or induce efflux pumps in bacteria causing them to become resistant against variety of other antibiotics.
What Is Triclosan?
Triclosan is an ingredient added to many consumer products intended to reduce or prevent bacterial contamination.
Triclosan is added to some antibacterial soaps and body washes, toothpastes, and some cosmetics—products regulated by the U.S. Food and Drug Administration (FDA).
Triclosan also can be found in clothing, kitchenware, furniture, and toys—products not regulated by the FDA.
Are There Benefits of Triclosan?
For some consumer products, there is evidence that triclosan provides a benefit. In 1997, FDA reviewed extensive effectiveness data on triclosan in Colgate Total toothpaste. The evidence showed that triclosan in that product was effective in preventing gingivitis.
For other products, such as over-the-counter (OTC) consumer antiseptic products, FDA has not received evidence that triclosan provides a benefit to human health. At this time, FDA doesn’t have evidence that triclosan in OTC consumer antibacterial soaps and body washes provides any benefit over washing with regular soap and water.
In December 2017, the FDA issued a final rule regarding certain OTC health-care antiseptic products. As a result, companies will not be able to use triclosan or 23 other active ingredients in these products without premarket review due to insufficient data regarding their safety and effectiveness. The FDA recently issued a final rule on OTC hand sanitizers and will continue to review the three active ingredients commonly used in hand sanitizers.
Triclosan is an aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Triclosan is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Triclosan has a role as an antibacterial agent, a fungicide, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an antimalarial, an EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor, a xenobiotic, a persistent organic pollutant and a drug allergen.
Triclosan is a member of phenols, an aromatic ether, a dichlorobenzene and a member of monochlorobenzenes.
Triclosan is a polychloro phenoxy phenol with antibacterial and antifungal activity.
Triclosan is added to toothpastes to prevent gingivitis and has been added to many household products for its topical antibiotic activity.
USES
-For triclosan (USEPA/OPP Pesticide Code: 054901) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
-Fungicide, bacteriostat.
-Triclosan is highly active against staphylococci and is used as an active agent in deodorants and antiseptic soaps.
-antimicrobial liquid and bar soaps, antiseptics, antimicrobial detergents, skin care and oral care products, for the antimicrobial treatment of plastics and textile products.
IDENTIFICATION AND USE:
Triclosan is a white to off-white crystalline powder.
Triclosan is used as fungicide and bacteriostat.
Triclosan is highly active against staphylococci and is used as an active agent in deodorants and antiseptic soaps.
Triclosan is also used as material preservative for industrial and household plastics and textiles.
Triclosan (2,4,4’ –trichloro-2’-hydroxydiphenyl ether) is an antimicrobial active ingredient incorporated into a variety of products to slow or stop the growth of bacteria, fungi, and mildew.
Triclosan has been used as a pesticide since 1969. Uses of triclosan as a pesticide include:
commercial, institutional, and industrial premises and equipment;
residential and public access premises; and
as a materials preservative.
Triclosan is a chemical with antibacterial properties. For more than 30 years, it has been used in consumer products such as detergents, soaps, skin cleansers, deodorants, lotions, creams, toothpastes, and dishwashing liquids. Triclosan can be added to other materials, such as textiles, to make them resistant to bacterial growth.
Triclosan is a chemical found in a wide range of household products. It:
acts as a preservative
helps to prevent odours
can kill or remove bacteria
stops the growth of bacteria, fungus and mildew
Examples of products that may contain triclosan include:
lotions
hand sanitizers
eye and face makeup
natural health products
fragrances and deodorants
toothpaste and mouthwash
soaps, skin cleansers, and shampoos
What Is Triclosan?
First made as a pesticide, triclosan has been around since the 1960s. In recent years, it made its way into a wide range of personal care items.
Triclosan is best known for its germ-killing power. That's why it has been used in so many hand soaps and body washes.
In water-based products like aftershave and makeup, it is a preservative.
Triclosan also helps fight odor, which is why it's in deodorants and body sprays.
Your toothpaste might have triclosan, too. Colgate Total is the only American Dental Association-approved toothpaste with this ingredient. The FDA approved it after reviewing data showing that it prevents gum disease.
Triclosan is a widely accepted antimicrobial ingredient because of its safety and antimicrobial efficacy.
Triclosan is a unique antimicrobial well suited for use in the health care industry in which mildness is a necessity to protect the health care worker during repeated use and antimicrobial activity is a necessity to protect public health.
Triclosan has demonstrated immediate, persistent, broad-spectrum antimicrobial effectiveness and utility in clinical health care settings.
Triclosan (2,4,4′-trichloro-2′-hydroxydiphenyl ether) is a nonionic, broad spectrum, antimicrobial agent that, because of its favorable safety profile, has been incorporated into a variety of many personal care products, including deodorant soaps, underarm deodorants, shower gels, and health care personnel handwashes.
Triclosan exhibits a moderate degree of substantivity to the skin, and, in many products, it imparts a remnant antimicrobial effect. A new application for triclosan is in oral dentifrices for plaque control. Currently under investigation in the United States, it is approved for oral care application in Canada and many European countries.
Triclosan is an organic compound with a slight phenolic smell.
Triclosan is commonly used as disinfectant or antiseptic to reduce and control bacterial contamination.
Because of its antibacterial properties it is included in many detergents, soaps, deodorants, toothpastes, cosmetics, shaving creams, mouth washes, and cleaning supplies, but also in consumer products, such as kitchen utensils, toys, bedding, socks, and trash bags.
The antimicrobial triclosan is used in a wide range of consumer products ranging from toothpaste, cleansers, socks, and baby toys. A bacteriostatic inhibitor of fatty acid synthesis, triclosan is extremely stable and accumulates in the environment.
Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Triclosan is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. Triclosan is also used in health care settings in surgical scrubs and personnel hand washes.
Triclosan is a biocidal compound with multiple targets in the cytoplasm and membrane. At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis. Triclosan binds to enoyl-acyl carrier protein reductase enzyme (ENR). This complex has increased affinity for NAD+ and forms a ternary complex. This complex is unable to participate in fatty acid synthesis, weakening the cell membrane and causing cell death. Humans do not have an ENR enzyme, and thus are not affected.
Triclosan is the active ingredient in a multitude of health care and consumer products with germicidal properties, which have flooded the market in recent years in response to the public's fear of communicable bacteria.
Although originally thought to kill bacteria by attacking multiple cellular targets, triclosan was recently shown to target a specific bacterial fatty acid biosynthetic enzyme, enoyl-[acyl-carrier protein] reductase, in Gram-negative and Gram-positive bacteria, as well as in the Mycobacteria.
Triclosan resistance mechanisms include target mutations, increased target expression, active efflux from the cell, and enzymatic inactivation/degradation. These are the same types of mechanisms involved in antibiotic resistance and some of them account for the observed cross-resistance with antibiotics in laboratory isolates.
Therefore, there is a link between triclosan and antibiotics, and the widespread use of triclosan-containing antiseptics and disinfectants may indeed aid in development of microbial resistance, in particular cross-resistance to antibiotics.
Application
A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.
Commonly used in:
Antibacterial soaps
Toothpaste
Deodorants
Cosmetics
School supplies (pencils, calculators, scissors)
Plastic toys
Cleaning supplies
Laundry products
Cutting boards
Textiles (clothing, shoes, bedding)
Carpets
Sealants/Adhesives
WHAT IS TRICLOSAN?
Triclosan is an antimicrobial agent found in a wide variety of antibacterial soaps and detergents, as well as in many deodorants, toothpastes, cosmetics, fabrics and plastics.
Triclosan was initially developed as a surgical scrub for medical professionals, but in recent years it has been added to a host of consumer products, from kitchen cutting boards to shoes, in order to kill bacteria and fungus and prevent odors.
FOUND IN: Antibacterial soaps and detergents, toothpaste and tooth whitening products, antiperspirants/deodorants, shaving products, creams, color cosmetics.
Triclosan (TCS) is a multi-purpose antimicrobial agent used as a common ingredient in everyday household personal care and consumer products.
Triclosan (TCS) is a whitish crystalline powder C12H7Cl3O2 that is a phenyl ether derivative used especially formerly as a broad-spectrum antibacterial agent.
Triclosan (TCS) is a commonly used antimicrobial agent that enters wastewater treatment plants (WWTPs) and the environment.
Triclosan is effective against many different bacteria as well as some fungi and protozoa it is widely used as an antiseptic, preservative and disinfectant in healthcare and in many consumer products including cosmetics, household cleaning products, plastic materials, toys and paints.
Triclosan is also included in surface of medical devices, plastic materials, textiles and kitchen utensils where it acts as a bactericide for extended periods of time.
Triclosan is incorporated in cosmetics mainly as a preservative, to stop bacteria from growing on the product and spoiling it.
Triclosan is also used as a biocide in many other personal care products such as deodorants, soaps and shower gels. Another biocidal application of triclosan is in toothpastes and other dental products to control plaque and improve the health of the gums.
Triclosan is used in a wide range of products intended for home use such as liquid soaps, detergents, chopping boards, children’s toys, carpets.
Triclosan and other biocides are increasingly added to clothing articles. The fabrics are treated with chemicals that trap the biocide inside so that they have antibacterial properties over a long period of time.
Triclosan is very effective at killing microorganisms so it is widely used in healthcare. For instance, many of the handwashes in hospitals and the detergents that medical personnel use to scrub up before surgery, contain triclosan.
Triclosan is used mainly in antiperspirants/deodorants, cleansers, and hand sanitizers as a preservative and an anti-bacterial agent.
Triclosan is an antibacterial and anti-fungal agent that slows or stops the growth of germs such as bacteria and mildew.
Triclosan is widely used as an antimicrobial ingredient in surgical hand scrubs and hand washes in hospitals and other healthcare facilities.
In toothpaste, triclosan can help combat the bacteria that cause gingivitis.
Triclosan is found in over-the-counter consumer antiseptic products such as hand wipes, rubs or gels, which can be used to clean hands when water is unavailable.
Triclosan is an antibacterial ingredient that’s added to many consumer products.
Triclosan’s contained in some first aid products, cosmetics, clothing, kitchenware, and toys.
Triclosan’s also found in at least one toothpaste in the United States.
Triclosan is an inhibitor of fatty acid synthase which has demonstrated bacteriostatic, antiseptic, and preservative properties.
Triclosan is a chemical with antibacterial properties that has been used widely in many consumer products for at least the past 20 years.
Triclosan is an ingredient in many detergents, soaps, skin cleansers, deodorants, lotions, creams, toothpastes, and dishwashing liquids.
Triclosan is also used as a material preservative to ward off bacteria, fungus, mildew, and odors in household items like toys, paints, mattresses, clothing, toilet bowls, and furniture fabric.
In terms of chemical structure and properties, triclosan is a white powdered solid with a slight aromatic/phenolic odor.
Triclosan is a chlorinated aromatic compound, which has functional groups representative of both ethers and phenols. Phenols often show anti-bacterial properties.
Triclosan is an antibacterial and antifungal agent that is used in a variety of products to prevent the growth of bacteria, fungus, and mildew, and to prevent odours, some examples include soaps, toothpastes, mouthwashes, deodorants, hand sanitizers, cosmetics, fabrics, plastics and household cleaning products.
Triclosan also has medical and pesticide applications. Questions exist about its use in products and as such it is regulated by the United States, Canada, and the European Union to protect consumers and the environment.
Triclosan is used to kill bacteria.
Triclosan was previously a common ingredient in liquid soaps labeled as “antibacterial” or “antimicrobial,” but this use was banned by the US Food and Drug Administration (FDA) as of September 2017.
Triclosan is still used in other personal care products, such as some toothpaste and cosmetics, although certain companies are phasing it out.
Triclosan is also added to many household products and building materials.
Triclosan is an antimicrobial agent added to a wide array of household products to prevent the growth of bacteria and fungus.
Triclosan has been found in human blood, urine and breast milk.
The chemical is a potential endocrine disruptor in humans.
Triclosan can also have negative impacts on environmental health, including aquatic systems.
What is triclosan?
Triclosan is an antimicrobial agent that is added to household and industrial products to prevent bacterial and fungal growth.
Triclosan’s chemical structure has striking similarities to thyroid hormones and to several known endocrine disruptors including diethylstilbestrol (DES) and bisphenol A (BPA).
Triclosan will be listed as an active ingredient on any product label, since it is considered a pesticide.
What is triclosan?
Triclosan is an antibacterial and antifungal agent.
How is triclosan used?
Triclosan is used as a material preservative and antimicrobial active ingredient in a wide range of cosmetics and personal care products, non-prescription drug products and natural health products.
Triclosan is also registered in Canada as a pesticide for use as a material preservative in the manufacture of textiles, leather, paper, plastic and rubber to stop the growth of bacteria, fungus, mildew, and to prevent odours.
Triclosan is an antibacterial and antifungal chemical agent used to stop the growth of bacteria, fungus and mildew.
Triclosan is found in numerous consumer products such as antibacterial soaps, deodorants, toothpastes, and cosmetics as well as furniture, toys, kitchenware, ...
Triclosan (Irgasan, Cloxifenolum) is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic.
Triclosan is a common synthetic antimicrobial agent incorporated in numerous industrial and personal care products.
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Triclosan is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodo ants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Triclosan is a broad-spectrum antimicrobial compound.
Triclosan was originally used in soaps, antiperspirants, and cosmetic toiletries as a germicide. Today, triclosan is incorporated into toothpaste because of its wide spectrum of antimicrobial activities and low toxicity.
1. Triclosan can be used as antiseptic and fungicide and applied to cosmetics, emulsions and resins; also can be used for the manufacture of disinfection medicated soap. The LD50 of mice subject to oral administration of this product is 4g/kg.
2. Triclosan can be used for the production of top-grade daily chemical product, the disinfectants of medical instrument as well as diet instrument as well as the preparation of the anti-bacterial, deodorant finishing agent of fabric.
3. Triclosan can also be applied to biochemical studies.
Triclosan is a kind of broad-spectrum antimicrobial agents which inhibit the type II fatty acid synthase (FAS-II) of bacteria and parasites, and also inhibits the mammalian fatty acid synthase (FASN), and may also have anticancer activity
Triclosan is colorless and long needle-like crystals with a melting point being around 54-57.3 ℃ (60-61 ℃).
Triclosan is slightly soluble in water and soluble in ethanol, acetone, ethyl ether and alkali solution.
Triclosan has a chloro-phenol odor.
Triclosan is an efficient broad-spectrum topical antimicrobial disinfectant which is normally white or off-white crystalline powder.
Triclosan has a slightly phenolic odor.
Triclosan is insoluble in water but easily soluble in organic solvents and alkali.
Triclosan has a relative stable chemical property and is heating-resistant and also resistant to acid and alkali hydrolysis without generating any symptoms of the toxicity and environmental pollution.
Triclosan is internationally recognized as a fungicide variety with specific efficacy.
Triclosan can kill bacteria such as Staphylococcus aureus, Escherichia coli and fungi such as Candida albicans.
Triclosan (CAS: 3380-34-5) is a chemical ingredient added to many consumer products designed to reduce or prevent bacterial contamination. This compound is present in some shower gels, toothpastes, detergents and cosmetic products.
Triclosan can also be found in children’s clothing, dishes, furniture and toys.
The use of triclosan (CAS: 3380-34-5) is frequently questioned. This common chemical is the subject of much research as it could pose a risk to public health and the environment.
About this substance
Helpful information
Triclosan is registered under the REACH Regulation but is not currently being manufactured in and / or imported to the European Economic Area.
Triclosan is used by consumers, in formulation or re-packing and in manufacturing.
Consumer Uses
Triclosan is used in the following products: cosmetics and personal care products.
Other release to the environment of Triclosan is likely to occur from: indoor use as reactive substance.
Article service life
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using this substance. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Release to the environment of this substance can occur from industrial use: formulation of mixtures.
Uses at industrial sites
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using this substance. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Manufacture
Release to the environment of Triclosan can occur from industrial use: manufacturing of the substance.
IUPAC NAMES:
2, 4, 4’ – Trichloro – 2’-hydroxy diphenyl ether (Triclosan)
2,4,4'-trichloro-2'-hydroxy-diphenyl-ether
2,4,4'-Trichloro-2'-hydroxydiphenyl Ether
2,4,4'-Trichloro-2'-hydroxydiphenyl ether
5-chloro-2-(2,4-dichlorophenoxy) phenol
5-Chloro-2-(2,4-dichlorophenoxy)phenol
5-chloro-2-(2,4-dichlorophenoxy)phenol
Irgasan
Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-
TRICLOSAN
Triclosan
triclosan
triclosan-
SYNONYMS:
2,4,4'-Trichloro-2'-hydroxydiphenyl Ether
2,4,4'-trichloro-2'-hydroxydiphenylether
222-182-2 [EINECS]
2988
3380-34-5 [RN]
4NM5039Y5X
5-Chlor-2-(2,4-dichlorphenoxy)benzolol [German]
5-Chlor-2-(2,4-dichlorphenoxy)phenol [German] [ACD/IUPAC Name]
5-chloro-2-(2,4-dichlorophenoxy)-phenol
5-Chloro-2-(2,4-dichlorophenoxy)phenol [ACD/IUPAC Name]
5-Chloro-2-(2,4-dichlorophénoxy)phénol [French] [ACD/IUPAC Name]
Cloxifenol
Irgasan (Triclosan)
Irgasan CH 3635
Irgasan DP 30
Irgasan DP 3000
Irgasan PE 30
Irgasan PG 60
KO1100000
MFCD00800992 [MDL number]
Microban B
Phenol, 5-chloro-2-(2,4-dichlorophenoxy)- [ACD/Index Name]
Ster-Zac
TCCP
ThDP
Tinosan AM 100
Triclosan [Wiki]
triclosanum [INN_la]
Ultrafresh NM 100
Vinyzene DP 7000
Yujiexin
Zilesan UV
2-(2,4-dichlorophenoxy)-5-chlorophenol
2,4,4'-Trichloro-2'-hydroxydiphenyl ether
2,4,4′-Trichloro-2′-hydroxydiphenyl ether
2,4,4'-Trichloro-2'-hydroxy diphenyl ether
2,4,4-trichloro-2-hydroxydiphenyl ether
2,4,4'-trichloro-2'-hydroxydiphenylethe
2-[2,4-bis(chloranyl)phenoxy]-5-chloranyl-phenol
2-Hydroxy-2',4,4'-trichlorodiphenyl Ether
