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TRIETHYLHEXYL CITRATE = Tris(2-Ethylhexyl) 2-hydroxypropane-1,2,3-tricarboxylate
CAS Number: 7147-34-4
What is Triethylhexyl Citrate?
Triethylhexyl Citrate is essentially odorless, clear oily liquids.
In cosmetics and personal care products, Triethylhexyl Citrate is mainly used in the formulation of nail care products.
Triethylhexyl Citrate can also be found in eye makeup.
Why is Triethylhexyl Citrate used in cosmetics and personal care products?
Triethylhexyl Citrate can be used as plasticizers for film-forming components.
Triethylhexyl Citrate and Acetyl Triethylhexyl Citrate can also be used as skin softening agents - emollients.
Test: 95.00 - 100.00
Food Chemicals Codex Listed: No
Boiling Point: 537.15°C. @ 760.00 mm Hg (estimated)
Flash Point: 305.00 °F. TCC ( 151.80 °C. ) (estimated)
logP (y/m): 9,970 (est.)
ECHA EINECS - REACH
Pre-Registration: 230-457-3
FDA UNII: ZS6ME39S45
Nikkaji Web: J227.395K
XlogP3-AA: 8.40 (estimated)
Molecular Weight: 528.77072000
Formula: C30 H56 O7
TRIETHYLHEXYL CITRATE is classified as:
plasticizer
plasticizer
skin care
CAS Number 7147-34-4
EINECS/ELINCS No: 230-457-3
COSING REF No: 80355
Chemical/IUPAC Name: Tris(2-Ethylhexyl) 2-hydroxypropane-1,2,3-tricarboxylate
"Good" in all categories.
INCI name: TRIETHYLHEXYL CITRATE
EINECS/ELINCS number: 230-457-3
Functions (INCI)
Emollient: Softens and softens the skin
Plasticizer: Softens and elasticizes another substance that cannot otherwise be easily deformed, dispersed or processed.
Skin care ingredient: Keeps skin in good condition
Triethylhexyl Citrate Non-toxic plasticizer tri(2-ethylhexyl) citrate was synthesized by using citric acid and 2-ethylhexanol as raw material and di(n-butyl)tin oxide as catalyst.
The effects of reaction temperature, catalyst amount, alcohol/acid molar ratio and reaction time on yield were investigated.
The products were analyzed by IR spectroscopy.
Optimum conditions for the synthesis of tri(2-ethylhexyl) citrate from di(n-butyl)tin oxide: molar ratio of 2-ethylhexanol to citric acid, 1 ∶ 3.60; amount of catalyst , 0.5 % of citric acid; reaction time is 120 minutes and reaction temperature is 150~160 ℃ .
Under optimum reaction conditions, the yield can be over 98%.
Triethylhexyl Citrate is the aliphatic ester that fits the formula
It is defined as a clear oily, essentially odorless liquid, soluble in common organic solvents.
Other names for this chemical are as follows:
2-(Acetyloxy)-1,2,3-Propanetriccarboxylic Acid, Triethyl Ester; 1,2,3-Propanetriccarboxylic Acid, 2-(Acetyloxy)-, Triethyl Ester and ATEC; Citric Acid, Acetyl Triethyl Ester; Tricarbalylic Acid, Beta-Acetoxytributyl Ester; Triethyl Acetylcitrate; and Triethyl Citrate, Acetate
Common Name 1,2,3-Propanetriccarboxylic acid, 2-hydroxy-, 1,2,3-tris(2-ethylhexyl) ester
CAS Number 7147-34-4
Molecular Weight 528.76100
Density 0.992g/cm3
Boiling Point 537.1ºC
Molecular Formula C30H56O7
No Melting Point
No MSDS
Flash Point 151.8ºC
Density 0.992g/cm3
Boiling Point 537.1ºC
Molecular Formula C30H56O7
Molecular Weight 528.76100
Flash Point 151.8ºC
Full Mass 528.40300
PSA 99.13000
LogP 6.77650
Refractive Index 1.466
The effect of storing platelets in a new polyvinyl chloride (PVC) plastic material with a butyryl-n-trihexyl citrate (BTHC) plasticizer was evaluated.
Triethylhexyl Citrate, PL 1240 container, ie PVC plastic with a different plasticizer, tri-(ethylhexyl)-tri-melitate, was used as a reference.
pH, pO2, pCO2, glucose, lactate, adenosine triphosphate, total adenine nucleotide content, lactate dehydrogenase and platelet factor 4 (PF4) measurements were made during 5 days of storage.
Similar results were noted when comparing Triethylhexyl Citrate, PL 2209 and PL 1240.
Differences in pO2 and pCO2 indicate higher gas permeability in PL 2209 than in PL 1240.
Significantly higher levels of PF4 were found in Triethylhexyl Citrate, PL 2209, but the difference cannot be attributed to the PL 2209 container itself.
Matched autologous reinfusion studies of 6 normal donors (111Indium), mean recovery values of 41.1% ± 7.4% (PL 2209) and 45.5% ± 7.7% (PL 1240), t1/2 66 ± 13 and 75 ± 5 hours after 5 days of storage gave.
Triethylhexyl Citrate, survival time (linear model) 6.3 ± 1.0 and 6.8 ± 0.7 and survival time (multi-hit model) 6.0 ± 0.7 and 6.5 ± 0.4, respectively day.
Only the difference in survival time (multiple hit) was significantly higher in the PL 1240.
Corrected number increments 12-24 hours after transfusion were 13,300 ± 10,800 (PL 2209) and 13,600 ± 11,600 (PL 1240), and there was no statistically significant difference.
These results suggest that Triethylhexyl Citrate, PL 2209 is an equivalent alternative to PL 1240 for 5 days of platelet storage.
Synonyms :
7147-34-4
triethylhexyl citrate
Tris(2-ethylhexyl) 2-hydroxypropane-1,2,3-tricarboxylate
UNII-ZS6ME39S45
ZS6ME39S45
1,2,3-Propanetriccarboxylic acid, 2-hydroxy-, 1,2,3-tris(2-ethylhexyl) ester
Citric acid, tris(2-ethylhexyl) ester
NSC25386
EINECS 230-457-3
1,2,3-Propanetriccarboxylic acid, 2-hydroxy-, tris(2-ethylhexyl) ester
tri(2-ethylhexyl) citrate
Tris-(2-ethylhexyl)citrate
SCHEMBL722548
DTXSID10991894
MGK 25386
NSC-25386
Q27295870
(3,4-Difluorophenyl)piperidin-4-yl-methanone hydrochloride
