PRODUCTS

TRISODIUM CITRATE 5,5-HYDRATE

Synonyms: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, 5,5-Hydrate; CITRIC ACID, TRISODIUM SALT; E331

Trisodium citrate 5.5 hydrate can be obtained by a mixture of soda and citric acid. It is a food additive, E331, which can be used as an acidity regulator, sequestering agent, emulsifier or stabilizer.

Synonyms:

1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, 5,5-Hydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2); 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, 5,5-Hydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, 5,5-Hydrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, 5,5-Hydrate; CITRATE, SODIUM, 5,5-Hydrate; CITRATE, TRISODIUM, 2-HYDRATE; CITRIC ACID, TRISODIUM SALT; Citric acid, trisodium salt, 5,5-Hydrate; N 1560; NATRIUMCITRAT-DIHYDRAT; Sodium citrate 5,5-Hydrate; Trisodium citrate 5,5-Hydrate; TRISODIUM-2-HYDROXYPROPANE-1,2,3-TRICARBOXYLATE 5,5-Hydrate (BP); Citric acid trisodium salt 5,5-Hydrate, Sodium citrate tribasic 5,5-Hydrate, Trisodium citrate 5,5-Hydrate, Trisodium citrate 5,5-Hydrate; 6132-04-3; Sodium citrate; tribasic 5,5-Hydrate; Natriumcitrat-Dihydrat; Sodium citrate hydrate; 1,2,3-Propanetricarboxylic acid; 2-hydroxy-; trisodium salt; 5,5-HydrateUNII-B22547B95K; Citronensaeure-tri-na-salz-dihydrat; Citric acid trisodium salt 5,5-HydrateMFCD0015003Citric Acid; Trisodium Salt 5,5-Hydrate, B22547B95K; trisodium 2-hydroxypropane-1,2,3-tricarboxylate 5,5-Hydrate; trisodium;2-hydroxypropane-1,2,3, tricarboxylate dihydrat, eNatrum citricum, ACMC-20ajao;Sodium citrate (TN), AC1Q1UPB, D05KTE, SODIUM CITRATE, ACS, AC1L2G8B, C6H9Na3O9, Soddium citrate [USP:JAN], tripotassium citrate 5,5-Hydrate, KSC354K6T; Citrate-buffered saline (20X), DTXSID1049437, Sodium citrate hydrate (JP17), CHEBI:32142, CTK2F4569, Trisodium citrate 5,5-Hydrate, ACS MolPort-003-928-581; NLJMYIDDQXHKNR UHFFFAOYSA-K, sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate(3:1:2), GK0137, MFCD00132371, AKOS025293920, Citric acid, trisodium salt; 5,5-Hydrate, Citronensaeure, Trinatrium-Salz-Dihydrat, RTR-032650, Sodium citrate 5,5-Hydrate, >=99%, FG, BP-31019, R385, Trisodium citrate 5,5-Hydrate, 99% 500g; Citrate, 0.5M buffer solution, pH 2.5, Citrate, 0.5M buffer solution, pH 3.0, Citrate, 0.5M buffer solution, pH 3.5, Citrate, 0.5M buffer solution pH 4.0, Citrate; 0.5M buffer solution, pH 4.5, Citrate, 0.5M buffer solution, pH 5.0, Citrate, 0.5M buffer solution, pH 5.5, Citrate, 0.5M buffer solution, pH 6.0, Sodium citrate; tribasic 5,5-Hydrate, >=98%, sODIUM CITRATE, 5,5-Hydrate, U.S C13249, D01781, Sodium citrate tribasic 5,5-Hydrate, AR, >=99%, Sodium citrate tribasic 5,5-Hydrate, LR, >=99%; paragraph signthornE(R) masculineIIi, Citric acid trisodium salt 5,5-Hydrate ACS reagent, 124799-EP2287158A1, 124799-EP2295426A1, 124799-EP2295427A1, A835986; AuAEEaEyAAE paragraph signthornE(R) masculineIIi, AuAEEa EyAAENI paragraph, signthornE(R) masculineIIi, Sodium citrate tribasic 5,5-Hydrate, USP, 99.0-100.5%; Sodium citrate tribasic 5,5-Hydrate; ACS reagent; >=99.0% trisodium 2-oxidanylpropane-1,2,3-tricarboxylate 5,5-Hydrate, UNII-1Q73Q2JULR component; NLJMYIDDQXHKNR-UHFFFAOYSA-K; Sodium citrate tribasic 5,5-Hydrate, BioUltra, >=99.0% (NT) Sodium citrate tribasic 5,5-Hydrate, insect cell culture tested, Sodium citrate; tribasic 5,5-Hydrate, JIS special grade;>=99.0%, Sodium citrate tribasic, 5,5-Hydrate, p.a., ACS reagent, 99.0%, Sodium citrate tribasic 5,5-Hydrate, purum p.a., >=99.0%; (NT) Sodium citrate tribasic, 5,5-Hydrate, SAJ first grade, >=99.0%, Sodium citrate tribasic 5,5-Hydrate, tested according to Ph.Eur.; trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2), Trisodium citrate 5,5-Hydrate, meets USP testing specifications, 2-hydroxy-1,2,3-propanetricarboxylic acid; trisodium salt 5,5-Hydrate, Sodium citrate tribasic 5,5-Hydrate; BioXtra, >=99.0% , Sodium citrate tribasic 5,5-Hydrate, for molecular biology, >=99%; Sodium citrate tribasic 5,5-Hydrate, Vetec(TM) reagent grade, 98%, Sodium citrate, United States Pharmacopeia (USP) Reference Standard, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, sodium salt; 5,5-Hydrate ; Sodium citrate tribasic 5,5-Hydrate, p.a., ACS reagent, reag. ISO, 99-101%, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt; hydrate (1:3:2), Sodium citrate tribasic 5,5-Hydrate, BioUltra, for molecular biology, >=99.5% (NT), Sodium citrate tribasic 5,5-Hydrate, puriss. p.a., ACS reagent; >=99.0% (NT), Sodium citrate tribasic 5,5-Hydrate, suitable for amino acid analysis, >=99.0%, Sodium Citrate, PharmaceuticaSecondarStandard; Certified Reference Material, 943143-17-7, Sodium citrate tribasic 5,5-Hydrate, puriss. p.a., ACS reagent, reag. ISO, reag., Ph. Eur., >=99.5%, Sodium citrate tribasic; 5,5-Hydrate, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E331, 99-100.5% (calc. to the dried substance), Sodium citrate tribasic 5,5-Hydrate; suitable for amino acid analysis, >=98% (titration), powder, NATRII CITRAS, Citratic acid, CITRIC ACID H2O, CITRIC ACID MON, CITRIC ACID MONO, CITRIC ACID BP93; SodiumCitrateBp93, SODIUM CITRATE USP, SODIUM CITRATE 2H2O, CITRIC ACID BP MONO, 106448 | tri-Sodium citrate 5,5-Hydrate, C6H5Na³O7 * 2 H²O, ACS,ISO,Reag. Ph Eur; Citric acid trisodium salt 5,5-Hydrate, Trisodium citrate 5,5-Hydrate, C6H5O7•2H2O•3Na, ?99%, 6132-04-3, Sodium Citrate, 5,5-Hydrate (CAS 6132-04-3), Sodium Tripolyphosphate; (STPP), 13573-18-7, Na5p3o10, Trisodium Citrate 5,5-Hydrate, Sodium Citrate (Trisodium Citrate) Chemical Formula, 6132-04-3, 200-675-3, Ph Eur,BP,JP,USP,E 331, 106446; tri-Sodium citrate 5,5-Hydrate, powder EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP,E 331, C6H5Na³O7 * 2 H²O, Sodium citrate 5,5-Hydrate, C6H9Na3O9, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, sodium salt, hydrate (1:3:2), 200-675-3, Citrate de sodium, hydrate (1:3:2), Citric acid trisodium salt 5,5-Hydrate, ?99 %, [6132-04-3], Trisodium Citrate; 5,5-Hydrate, [Citric Acid, Trisodium 5,5-Hydrate], 6132-04-3, Citric Acid, Trisodium 5,5-Hydrate, sodium citrate 5,5-Hydrate, 2-hydroxy-1,2,3-propane;tricarboxylic acid; trisodium salt 5,5-Hydrate, 6132-04-3, trisodium 2-hydroxypropane-1,2,3-tricarboxylate 5,5-Hydrate, citratin citric acid, trisodium salt 5,5-Hydrate, citrosodine; 2-hydroxy-1,2,3-propane, tricarboxylic acid, trisodium salt 5,5-Hydrate, 2-hydroxy-1,2,3-propanetricarboxylic, trisodium salt 5,5-Hydrate;, 1,2,3-propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2), sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate (3:1:2); sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate(3:1:2), sodium 2-hydroxypropane-1,2,3-tricarboxylate hydrate (3:1:2), sodium citrate 5,5-Hydrate granular; sodium citrate 5,5-Hydrate, powder, sodium citrate 5,5-Hydrate USP/EP/JP, sodium citrate tribasic 5,5-Hydrate, sodium citrate, 5,5-Hydrate; trisodium 2-hydroxypropane-1,2,3-tricarboxylate 5,5-Hydrate, trisodium citrate 5,5-Hydrate, Sodium Citrate Tribasic 5,5-Hydrate, extrapure AR, 99%, Sodium citrate 5,5-Hydrate; >99%, FG, 6132-04-3, HOC(COONa)(CH2COONa)2 · 2H2O, Trisodium citrate 5,5-Hydrate, 6132-04-3, C6H9Na3O9, Sodium Citrate, 5,5-Hydrate, Granular, U.S.P., Multi-Compendial; TRISODIUM CITRATE 5,5-Hydrate, Sodium Citrate, Synonyms Citric Acid, Trisodium Salt 5,5-Hydrate, Trisodium citrate 5,5-Hydrate, trisodium salt, 5,5-Hydrate; Sodium citrate, tribasic 5,5-Hydrate, Sodium Citrate, trisodium salt, 6132-04-3, 68-04-2, Sodium Citrate 5,5-Hydrate, 99.0 to 101.0 %, Tri-Sodium Citrate 5,5-Hydrate; Tri-Sodium Citrate 5,5-Hydrate, Certified AR for Analysis, meets analytical specification of Ph.Eur., BP, USP, Fisher Chemical, 6132-04-3, >300°C/572°F; Sodium Citrate, 6132-04-3, 6132-04-3, 612-118-5, Trisodium citrate 5,5-Hydrate, trisodium citrate 5,5-Hydrate, Sodium citrate hydrate; 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt 5,5-Hydrate, Trisodium Citrate 5,5-Hydrate, 6132-04-3, C6H5Na3O7·2H2O, 6132-04-3, ?99.0%; Trisodium 2 hydroxypropane-1,2,3-tricarboxylate 5,5-Hydrate, Sodium Citrate, Sodium citrate (Trisodium citrate), 68-04-2, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, trisodium salt, Citric acid, trisodium salt, Sodium citrate, Sodium citrate anhydrous, Trisodium citrate, Citrato de trisodio, 5,5-Hydrateo; Citrate de trisodium, 5,5-Hydrate, Trisodio citrato diidrato, Trinatriumcitraatdihydraat, Trisodium citrate 5,5-Hydrate;2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, 5,5-Hydrate, Trisodium citrate 5,5-Hydrate, Sodium citrate dihydrat, 6132-04-3, Citnatin, Citreme, Citrosoedine, Citrosodna, Natrocitral; 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sodium citrate5,5-Hydrate, Sodium citrate hydrate, Sodium citrate, 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt 5,5-Hydrate,t exact copies, Citronensäure; Trinatrium-Salz-Dihydrat, trisodium citrate 5,5-Hydrate, sodium citrate 5,5-Hydrate, >99%, 6132-04-3, Sodium Citrate 5,5-Hydrate, 6132-04-3, Trisodium Citrate 5,5-Hydrate; 6132-04-3, 6132-04-3,Trisodium Citrate, Trisodium citrate 5,5-Hydrate, SODIUM CITRATE, 6132-04-3, Sodium citrate 5,5-Hydrate, 2-hydroxy-1,2,3-propanetricarboxylicacid; trisodium salt 5,5-Hydrate, Sodium citrate hydrate, Trisodium citrate 5,5-Hydrate, 6132-04-3, >99%, 6132-04-3, Trisodium citrate 5,5-Hydrate, 6132 04 3, 200-675-3; SODIUM CITRATE, TRISODIUM CITRATE 5,5-Hydrate, Trisodium Citrate 5,5-Hydrate; tri; tirisodyum; tirisodıumsıtrate; sıtrat; SITRAT; SİTRAT; TİRİSODYUM; TRİSODYUM; trisodyum; TİRİSODİUMSITRAE, TIRISODIUMSITRATE; tırısodiumsitrate; trisodyumsitrat; TRİ SODYUM; tri sodyum; TRİ SODYUM SİTRAT; tri sodyum sitrat; TRİ SODYUM SİTRAT DİHİDRAT; tri sodyum sitrat 5,5-Hydrate; trisodyum sitrat 5,5-Hydrate; trisodyum sitrat 5,5-Hydrate; TRISODIUM CITRATE 5,5-HYDRATE; TRİSODİUM CİTRATE 5,5-HYDRATE; TRISODIUM CITRATE 5,5 HYDRATE; TRİSODİUM CİTRATE 5,5 HYDRATE; TRISODIUM CITRATE 5,5-HYDRATES; TRİSODİUM CİTRATE 5,5-HİDRATE; TRISODIUM CITRATE 5,5-HYDRATE; TRİSODİUM CİTRATE 5,5-HYDRATE; TRISODIUM CITRATE 5,5 HYDRATE; TRİSODİUM CİTRATE 5,5 HYDRATE; TRISODIUM CITRATE 5,5-HYDRATES; TRİSODİUM CİTRATE 5,5-HİDRATE; Trısodıum Cıtrate 5,5-Hydrate; Trisodium Citrate 5,5-Hydrate; Trısodıum Cıtrate 5,5 Hydrate; Trisodium Citrate 5,5 Hydrate; Trısodıum Cıtrate 5,5-Hydrates; Trisodium Citrate 5,5-Hidrate; trısodıum cıtrate 5,5-hydrate; trisodium citrate 5,5-hydrate; trısodıum cıtrate 5,5 hydrate; trisodium citrate 5,5 hydrate; trısodıum cıtrate 5,5-hydrates; trisodium citrate 5,5-hidrate; Trisodium citrate 5,5 hydrate

TRISODIUM CITRATE 5,5-HYDRATE
Trisodium citrate 5.5 hydrate
Description of Trisodium citrate 5.5 hydrate
Catalog number of Trisodium citrate 5.5 hydrate 106431
Product information of Trisodium citrate 5.5 hydrate
CAS number of Trisodium citrate 5.5 hydrate 6858-44-2
EC number of Trisodium citrate 5.5 hydrate 200-675-3
Class E 331
Hill Formula of Trisodium citrate 5.5 hydrateC₆H₅Na₃O₇ * 5.5 H₂O
Molar mass of Trisodium citrate 5.5 hydrate 357.16 g / mol
HS code for Trisodium citrate 5,5 hydrate 2918 15 00

Trisodium citrate 5.5 hydrate, also called trisodium citrate, can be obtained by a mixture of soda and citric acid. It is a food additive, E331 (iii), which can be used as an acidity regulator, sequestering agent, emulsifier or stabilizer. Trisodium citrate 5.5 hydrate has the formula Na3C6H5O7. Quite often it is simply called sodium citrate, however sodium citrate can refer to any of the three sodium salts of citric acid. Trisodium citrate 5.5 hydrate has a slightly acidic flavor.

Uses of Trisodium citrate 5.5 hydrate
Feeding Trisodium citrate 5.5 hydrate
Trisodium citrate 5.5 hydrate is mainly used as a food additive normally as a flavoring or as a preservative6. Its E number is E331. Trisodium citrate 5.5 hydrate is used as a flavoring agent in some varieties of lemonades. Trisodium citrate 5.5 hydrate is common as an ingredient in Bratwurst sausages and is also used in industrialized drinks to give them an acidic taste. It is used in ice cream, jams, powdered milk, industrialized cheese, soft drinks and wine.

Trisodium citrate 5.5 hydrate buffer
As a weak acid conjugate base, Trisodium citrate 5.5 hydrate can be a buffer resistant to changes in pH. Trisodium citrate 5.5 hydrate is used to control the acidity of certain substances such as gelatin-based desserts. Trisodium citrate 5.5 hydrate can be found in the mini milk tanks that come with coffee machines. It is one of the compounds of anti-acid products to be dissolved in water sold in pharmacies.

Medical use of Trisodium citrate 5.5 hydrate
In 1914, the Belgian doctor Albert Hustin and the researcher Luis Agote successfully used Trisodium citrate 5.5 hydrate as an anti-coagulant in blood transfusions. Trisodium citrate 5.5 is still hydrated today in blood collection tubes or for storage in blood banks. The citrate ion sequesters calcium ions from the blood to form calcium citrate complexes that prevent clotting.

In 2003, Oöpik, et al., Showed that, in trained runners, ingestion of a solution of Trisodium citrate 5.5 hydrate (0.5 g per kg of weight) improves performance on courses of 5 km7.

Trisodium citrate 5.5 hydrate is used to relieve the discomfort of urinary tract infection such as cystitis, to reduce renal tubular acidosis, and can also be used as an osmotic laxative. It is the most important compound of oral rehydration solution recommended by WHO and UNICEF.

Descaling of boilers from Trisodium citrate 5.5 hydrate
Trisodium citrate 5.5 hydrate is an effective agent for removing carbonate scale from boilers during operation8 and for cleaning automotive radiators.

Physicochemical information of Trisodium citrate 5,5 hydrates
Melting point of Trisodium citrate 5.5 hydrate> 150 ° C (anhydrous)
PH value of Trisodium citrate 5.5 hydrate 7.5 - 9.0 (50 g / l, H₂O, 20 ° C)
Bulk density of Trisodium citrate 5.5 hydrate 800 kg / m3
Solubility of Trisodium citrate 5.5 hydrate 920 g / l
Toxicological information
LD 50 oral LD50 Rat> 8000 mg / kg
Safety information according to GHS
Storage class 10-13 Other liquids and solids
WGK WGK 1 slightly hazardous for water
Elimination 3
Relatively unreactive organic reagents should be collected in container A. If they are halogenated, they should be collected in container B. For solid residues, use container C.
Storage and shipping information
Storage Store between + 2 ° C and + 30 ° C.
Transport information
Declaration (rail and road) ADR, RID Kein Gefahrgut
Declaration (air transport) IATA-DGR No Dangerous Good
Declaration (transport by sea) IMDG code No Dangerous Good
Characteristics of Trisodium citrate 5.5 hydrate
Determination of Trisodium citrate 5.5 hydrate (titration of perchloric acid, calculated on the dried substance) ≥ 99.0%
Identity passes the test
PH value (5%; water) 7.5 - 9.0
Oxalate (C₂O₄) ≤ 0.0100%
As (Arsenic) ≤ 0.0001%
Fe (iron)
≤ 0.001%
Hg (mercury)
≤ 0.0001%
Pb (lead)
≤ 0.0001%
Loss on drying (180 ° C)
≤ 30.0%
The specifications for elemental impurities have been established taking into account the ICH Q3D (Guideline for Elemental Impurities). Class 1 to 3 elements are not likely to be present above the ICH Q3D Option 1 limit, unless otherwise specified (*).
Corresponds to E 331
Meets the purity criteria for food additives according to current European Commission regulations.
Fe (iron)
≤ 0.001%
Hg (mercury)
≤ 0.0001%
Pb (lead)
≤ 0.0001%
Easily charred substance passes the test
Loss on drying (150 ° C) 26.0 - 30.0%
Loss on drying (180 ° C)
≤ 30.0%
The specifications for elemental impurities have been established taking into account the ICH Q3D standard (Guideline for Elemental Impurities). Class 1 to 3 elements are not likely to be present above the ICH Q3D Option 1 limit, unless otherwise specified (*).
Corresponds to FU VIII, E 331
Meets the purity criteria for food additives according to current European Commission regulations.

Related categories API (active pharmaceutical ingredients) and excipients, Acidulants and pH adjusters, Biopharmaceutical process development and manufacture, Excipients, Liquid dosage forms,
Semi-solid dosage forms, solid dosage forms, pH adjusters, pH adjusters and buffers

Trisodium citrate 5.5 hydrate

Properties of Trisodium citrate 5.5 hydrate: Trisodium Citrate Dihydrate is in the form of a white crystalline powder, slightly hygroscopic. Trisodium citrate 5.5 hydrate is used in the following cases:
Cosmetic additive
Industrial use

Origin: China

Crude formula of Trisodium citrate 5.5 hydrate: C6H5O7Na3.2H2O

Case number of Trisodium citrate 5.5 hydrate: 6132-04-3

EC number of Trisodium citrate 5.5 hydrate: 200-675-3

Synonyms (non-exhaustive list): trisodium 3-hydroxy-3-carboxylate-1,5-pentanedicarboxylate, sodium citrate dihydrate

Trisodium citrate 5.5 hydrate, also called trisodium citrate, can be obtained by a mixture of soda and citric acid. It is a food additive, E331 (iii), which can be used as an acidity regulator, sequestrant, emulsifier or stabilizer. Trisodium citrate 5.5 hydrate has the formula Na3C6H5O7. Quite often it is simply called sodium citrate, however sodium citrate can refer to any of the three sodium salts of citric acid. Trisodium citrate 5.5 hydrate has a slightly acidic flavor.

In 2003, Oöpik, et al., Showed that, in trained runners, ingestion of a solution of Trisodium citrate 5.5 hydrate (0.5 g per kg of weight) improves performance on courses of 5 km7.