PRODUCTS

TROMETHAMINE

Tromethamine is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer.
Tromethamine is extensively used in biochemistry and molecular biology.

CAS Number: 77-86-1 (free base)
1185-53-1 (hydrochloride)
6850-28-8 (acetate salt)
EC Number: 201-064-4
Chemical formula: C4H11NO3
Molar mass: 121.136 g·mol−1

SYNONYMS:
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, Addex-Tham, Aminotrimethylolmethane, Aminotris(hydroxymethyl)methane, Methanamine, 1,1,1-tris(hydroxymethyl)-, Pehanorm, Talatrol, Tham-E, Trimethylolaminomethane, Tris, Tris amino, Tris buffer, Tris(hydroxymethyl)aminomethane, Tris(hydroxymethyl)methanamine, Tris(hydroxymethyl)methylamine, Tris-steril, Trisamin, Trisamine, Trisaminol, Trispuffer, Trizma, Trometamol, Trometamole, Tromethane, Tromethanmin, Tutofusin tris, THAM, Apiroserum Tham, Methylamine, 1,1,1-tris(hydroxymethyl)-, 2-(Hydroxymethyl)-2-amino-1,3-propanediol, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, 2-Amino-2-methylol-1,3-propanediol, Tromethamin, Aminotri(hydroxymethyl)methane, TAM, Trigmo base, Triladyl, 2-Amino-2-hydroxymethylpropanediol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris (hydroxymethyl)aminoethane, Tris base, Tris, free base, Trizma base, NSC 6365, Tris (buffering agent), 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol, Tromethamine, Trismat®, Trometamol, TRIS, TRIS Base, Trizma(R) base, BioPerformance Certified, meets EP, USP testing specifications, cell culture tested, >=99.9% (titration), Trizma(R) base, certified reference material for titrimetry, certified by BAM, according to ISO 17025, >=99.5%, Trometamol(Tris),Proteomics Grade, EC 201-064-4, NSC65434, THAM-E COMPONENT TROMETHAMINE, 1,1,1-tris(hydroxymethyl)methanamine, Trometamol(Tris),for molecular biology, NCGC00159412-02, NCGC00159412-04, Tris buffertris-hydroxymethyl-aminomethan, TROMETHAMINE (II), TROMETHAMINE [II], Trometamolum (INN-Latin), Tromethamine (USAN:USP), TROMETAMOL (MART.), TROMETAMOL [MART.], WLN: Q1XZ1Q1Q, 136760-04-8, Trometamol(Tris), inverted exclamation markY99.5%, TROMETHAMINE (USP-RS), TROMETHAMINE [USP-RS], 4-Anilino-1-(2-hydroxyethylamino)anthracene-9,11-dione, Tromethamine [USAN], (tris(hydroxymethyl)aminomethane), [tris(hydroxymethyl)aminomethane], TROMETAMOL (EP MONOGRAPH), TROMETAMOL [EP MONOGRAPH], 1, 2-amino-2-(hydroxymethyl)-, Triladyl, Trigmo base, TROMETHAMINE (USP MONOGRAPH), TROMETHAMINE [USP MONOGRAPH], MFCD00132476, TRIS(HYDROXY-D-METHYL)AMINO-D2-METHANE, 98 ATOM % D, Methanamine,1,1-tris(hydroxymethyl)-, Methylamine,1,1-tris(hydroxymethyl)-, tris(hydroxymethyl)amino methane, .beta.-D-ribo-Hexopyranose, 1,6-anhydro-3-deoxy-2-O-(1-methylethyl)-4-O-(phenylmethyl)-, CAS-77-86-1, Tris(hydroxymethyl)aminomethane, >=99.8%, propane, 2-amino-1,3-dihydroxy-2-hydroxymethyl-, Tris(hydroxymethyl)aminomethane, Electrophoresis Grade, Tris-hydroxymethyl-aminomethan [German], trometamolo, Tromethamin, Aminotri(hydroxymethyl)methane, tris-buffer, tris-amine, Tro.meta.mole, Tris(Hydroxymethyl)-Aminomethane, Tro.meta.mol, 1gng, tris base solution, 83147-39-1, THAM (Standard), TRS, Tromethamine (USP), TRIS Ultrapure, EP, 1h4n, Trometamol (JAN/INN), TROMETAMOL [JAN], TROMETHAMINE [MI], SCHEMBL975, trishydroxymethylmethylamine, THAM (TN), TROMETHAMINE [HSDB], NCIOpen2_000263, NCIOpen2_001720, TROMETAMOL [WHO-DD], TROMETHAMINE [VANDF], Oprea1_677781, trishydroxymethyl aminomethane, tris-hydroxymethyl-methylamine, MLS000028643, tris hydroxymethyl aminomethane, tris-(hydroxymethyl)methylamine, Tris (hydroxymethyl)aminoethane, GTPL7328, tris (hydroxymethyl)aminomethane, CHEMBL1200391, tris (hydroxymethyl) methylamine, HY-D0227C, HY-D0227D, HY-D0227E, HY-D0227R, tris (hydroxymethyl) aminomethane, B05BB03, B05XX02, 2-Amino-2-hydroxymethylpropanediol, HMS3652L05, HMS3885H09, tris-(hydroxymethyl)-amino-methane, TROMETHAMINE [ORANGE BOOK], 2-amino-2-hydroxymethyl-propane-1, Tris-Base, molecular biology grade, BCP05578, HY-D0227, STR03166, Tox21_111645, Tox21_201646, Tox21_303167, BBL000011, NSC-65434, s4176, STK379529, 1,1,1-tris(hydroxymethyl)methylamine, 2-amino-2-methylol-propane-1,3-diol, AKOS000121321, Tox21_111645_1, 1,1,1-Tris(hydroxymethyl)-methylamine, CCG-214012, CS-W018524, DB03754, PB47623, Trizma(R) base, >=99.0% (T), Tris(hydroxymethyl)aminomethane, >=99%, TROMETHAMINE COMPONENT OF THAM-E, NCGC00159412-03, NCGC00159412-05, NCGC00257164-01, NCGC00259195-01, BP-13394, DA-58763, SMR000059179, Tris(hydroxymethyl)aminomethane ACS grade, Tris(hydroxymethyl)aminomethane, ultrapure, 2-amino-2-[hydroxymethyl]-1,3-propandiol, DB-091324, DS-014869, Methanamine, 1, 1,1-tris(hydroxymethyl)-, Tris acidimetric, NIST(R) SRM(R) 723e, A0321, CS-0201542, CS-0201543, CS-0201544, NS00002396, SW219208-1, T2516, TRIS-buffered saline (TBS, 10X) pH 7.4, TRIS-buffered saline (TBS, 10X) pH 7.6, TRIS-buffered saline (TBS, 10X) pH 8.0, TRIS-buffered saline (TBS, 20X) pH 7.4, 2-(Hydroxymethyl)-2-amino-1, 3-propanediol, 2-amino-2-(hydroxyl-methyl)propane-1,3-diol, 2-amino-2-(hydroxymethyl) propane-1,3-diol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol;, 2-Amino-2-(hydroxymethyl)-propane-1,3-diol, EN300-21687, Trizma(R) base, BioUltra, >=99.8% (T), Trizma(R) base, tested according to Ph.Eur., Trometamol (part of FOSFOMYCIN TROMETAMOL), Tromethamine, meets USP testing specifications, C07182, D00396, M02623, P17498, SBI-0653855.0001, AB00443859_03, AB00443859_04, Q413961, Sigma 7-9(R), >=99% (titration), crystalline, SR-01000944234, Trizma(R) base, puriss. p.a., >=99.7% (T), J-610076, SR-01000944234-1, Trizma(R) base, >=99.9% (titration), crystalline, Trizma(R) base, Vetec(TM) reagent grade, >=99%, W-104296, BIRD-K47978074-001-02-4, BIRD-K47978074-001-03-2, Tris(hydroxymethyl)aminomethane, ACS reagent, 99.9%, F0001-1979, Tris(hydroxymethyl)aminomethane, ACS reagent, >=99.8%, Tris(hydroxymethyl)aminomethane, Molecular Biology Grade, TRIS-buffered saline (TBS, 10X, high salt) pH 7.4, Z104509094, Tris(hydroxymethyl)aminomethane, p.a., ACS reagent, 99.8%, Tris(hydroxymethyl)aminomethane, ultrapure grade, >=99.9%, Trizma(R) base, puriss. p.a., buffer substance, >=99.5%, Trometamol, European Pharmacopoeia (EP) Reference Standard, Tris(hydroxymethyl)aminomethane, JIS special grade, >=99.0%, TRIS-buffered saline (TBS, 10X) pH 7.4, for Western blot, InChI=1/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H, Trizma(R) base, anhydrous, free-flowing, Redi-Dri(TM), >=99.9%, Trizma(R) base, BioUltra, for molecular biology, >=99.8% (T), Tromethamine, United States Pharmacopeia (USP) Reference Standard, Trizma(R) base, cell culture tested, >=99.9% (titration), crystalline, Trizma(R) base, BioXtra, pH 10.5-12.0 (1 M in H2O), >=99.9% (titration), Trizma(R) base, Primary Standard and Buffer, >=99.9% (titration), crystalline, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, TRIS, Tris, Tris base, Tris buffer, Trizma, Trisamine, THAM, Tromethamine, Trometamol, Tromethane, Trisaminol, Tris(hydroxymethyl)aminomethane, Trometamol, TROMETHAMINE, 77-86-1, Tris(Hydroxymethyl)aminomethane, Tris, Tham, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, Trisamine, Trizma, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris buffer, Tris base, Tromethane, Tris-base, Trisaminol, Pehanorm, Talatrol, Trisamin, Trispuffer, Tutofusin tris, Addex-tham, Tris-steril, 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, Tris, free base, Trimethylolaminomethane, Aminotrimethylolmethane, Aminotris(hydroxymethyl)methane, Tromethanmin, Tris (buffering agent), Tris Amino, Tris(hydroxymethyl)methanamine, Tris(hydroxymethyl)methylamine, THAM-E, Tromethamolum, Trometamole, Trizma base, Trometamolum, 2-Amino-2-methylol-1,3-propanediol, Caswell No. 036, Tris-hydroxymethylaminomethane, Tri(hydroxymethyl)aminomethane, bakerbond(tm) cyano (cn), NSC 6365, Methylamine, 1,1,1-tris(hydroxymethyl)-, 2-(Hydroxymethyl)-2-amino-1,3-propanediol, ABX (ANTIBODY EXCHANGER), HSDB 3408, Tris-Amino, Methanamine, 1,1,1-tris(hydroxymethyl)-, Trometamolum [INN-Latin], NSC-6365, EINECS 201-064-4, UNII-023C2WHX2V, MFCD00004679, Trometamol [INN], Tris-hydroxymethyl-aminomethan, EPA Pesticide Chemical Code 083901, 023C2WHX2V, CHEBI:9754, WP QUAT (STRONG ANION EXCHANGER), 2-Amino-2-hydroxymethyl-1,3-propanediol, DTXSID2023723, Tris(hydroxymethyly)amino methane, AI3-03948, NSC6365, 126850-03-1, 126850-06-4, 126850-08-6, Tromethamine [USAN:USP], AMINO (NH2) NARROW-PORE MEDIA-NORMAL PHASE, DTXCID503723, tris(hydroxymethyl) aminomethane, 126850-05-3, Tris-(hydroxymethyl)-aminomethane

Tromethamine is an aliphatic compound.
Tromethamine is a pharmaceutical medication that belongs to a class of drugs known as endothelin receptor antagonists.
Tromethamine is primarily used for managing certain cardiovascular and pulmonary conditions.

This guide provides an overview of Tromethamine, including its uses, dosage recommendations, potential side effects, interactions with other medicines, benefits, and frequently asked questions.
Tromethamine is a proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.

Tromethamine is an organic amine proton acceptor.
Tromethamine is a primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group.
Tromethamine is a compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 ℃; pKa = 7.82 at 37 ℃.

Tromethamine has a role as a buffer.
Tromethamine is a triol and a primary amino compound.
Tromethamine is a conjugate base of a member of Htris.

Tromethamine is an organic amine proton acceptor.
Tromethamine is a small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1965 and is indicated for acidosis and has 7 investigational indications.

Tromethamine is indicated for the prevention and correction of metabolic acidosis.
When administered intravenously as a 0.3 M solution, tromethamine acts as a proton acceptor and prevents or corrects acidosis by actively binding hydrogen ions (H+).

Tromethamine binds not only cations of fixed or metabolic acids, but also hydrogen ions of carbonic acid, thus increasing bicarbonate anion (HCO3‾).
TromeThamine also acts as an osmotic diuretic, increasing urine flow, urinary pH, and excretion of fixed acids, carbon dioxide and electrolytes.
A significant fraction of tromethamine (30% at pH 7.40) is not ionized and therefore is capable of reaching equilibrium in total body water.

This portion may penetrate cells and may neutralize acidic ions of the intracellular fluid.
Tris, or tris(hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH2)3CNH2.
Tromethamine is extensively used in biochemistry and molecular biology as a component of buffer solutions such as in TAE and TBE buffers, especially for solutions of nucleic acids.

Tromethamine contains a primary amine and thus undergoes the reactions associated with typical amines, e.g., condensations with aldehydes.
Tris also complexes with metal ions in solution.
In medicine, tromethamine is occasionally used as a drug, given in intensive care for its properties as a buffer for the treatment of severe metabolic acidosis in specific circumstances.

Some medications are formulated as the "tromethamine salt" including Hemabate (carboprost as trometamol salt), and "ketorolac trometamol".
In 2023 a strain of Pseudomonas hunanensis was found to be able to degrade TRIS buffer.
Since Tris' pKa is more strongly temperature dependent, Tromethamine's use is not recommended in biochemical applications requiring consistent pH over a range of temperatures.

Moreover, the temperature dependance of the pKa (and in turn buffer solution pH) makes pH adjustment difficult.
Tromethamine makes blood and urine more alkaline or less acidic.

Tromethamine is used to treat metabolic acidosis, a condition where the body produces too much acid or when the kidneys are not removing enough acid from the body.
Tromethamine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

USES and APPLICATIONS of TROMETHAMINE:
Tromethamine is an oral medication designed to block the action of endothelin, a natural substance in the body that narrows blood vessels.
By inhibiting endothelin, Tromethamine helps to relax blood vessels, improving blood flow and reducing strain on the heart and lungs.
The useful buffer range for Tromethamine (pH 7–9) coincides with the physiological pH typical of most living organisms.

This, and its low cost, make Tromethamine one of the most common buffers in the biology/biochemistry laboratory.
Tromethamine is also used as a primary standard to standardize acid solutions for chemical analysis.
Tromethamine is used to increase permeability of cell membranes.

Tromethamine is a component of the Moderna COVID-19 vaccine and the Pfizer-BioNTech COVID-19 vaccine for use in children 5 through 11 years of age.
Medical: Tromethamine (usually known as THAM in this context) is used as alternative to sodium bicarbonate in the treatment of metabolic acidosis.
Tromethamine is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer.

Because tromethamine (in the form of R-NH2) is a proton acceptor with a pK of 7.8, it is an effective buffer that can be used to maintain the pH of body fluids.
Tromethamine is used to treat or prevent acid problems in the blood.

Tromethamine is used as an emulsifying agent excipient.
Tromethamine belongs to the group of pH-regulators and excipients.

The active substance, Tromethamine, alkalifies and buffers.
Tromethamine is used for the treatment of metabolic azidoses or for the stabilization of finished dosage forms.

Tromethamine is an organic amine proton acceptor.
Tromethamine is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer

Tromethamine affects the balance of water and electrolytes in the body.
Tromethamine is used to treat metabolic acidosis (an electrolyte imbalance).
Metabolic acidosis can have many causes.

Tromethamine often occurs after heart bypass surgery or cardiac arrest.
Tromethamine may also be used for purposes not listed in this medication guide.

-Approved Uses of Tromethamine:
Pulmonary Arterial Hypertension (PAH): Tromethamine is primarily prescribed for treating PAH, a condition where high blood pressure in the lungs makes it difficult for the heart to pump blood efficiently.
Secondary Raynaud’s Phenomenon (Off-label Use): In some cases, Tromethamine is used to reduce the frequency and severity of Raynaud’s episodes.

PREPARATION OF TROMETHAMINE:
Tromethamine is prepared industrially by the exhaustive condensation of nitromethane with formaldehyde under basic conditions (i.e. repeated Henry reactions) to produce the intermediate (HOCH2)3CNO2, which is subsequently hydrogenated to give the final product.

BUFFERING FEATURES OF TROMETHAMINE:
The conjugate acid of Tromethamine has a pKa of 8.07 at 25 °C, which implies that the buffer has an effective pH range between 7.1 and 9.1 (pKa ± 1) at room temperature.

*Buffer details
In general, as temperature decreases from 25 °C to 5 °C the pH of a Tromethamine buffer will increase an average of 0.03 units per degree.

As temperature rises from 25 °C to 37 °C, the pH of a Tromethamine buffer will decrease an average of 0.025 units per degree.
In general, a 10-fold increase in Tromethamine buffer concentration will lead to a 0.05 unit increase in pH and vice versa.

Silver-containing single-junction pH electrodes (e.g., silver chloride electrodes) are incompatible with Tromethamine since an Ag-tris precipitate forms which clogs the junction.
Double-junction electrodes are resistant to this problem, and non-silver containing electrodes are immune.

*Buffer inhibition
Tromethamine inhibits a number of enzymes, and therefore should be used with care when studying proteins.
Tromethamine can also inhibit enzyme activity via chelation of metal ions.

HOW DOES TROMETHAMINE WORK?
Tromethamine works by blocking endothelin receptors (ET-A and ET-B) on the smooth muscles lining blood vessels.
This action reduces blood vessel constriction, improves oxygen delivery to tissues, and alleviates symptoms like breathlessness and fatigue associated with PAH.

PHYSICAL and CHEMICAL PROPERTIES of TROMETHAMINE:
Chemical formula: C4H11NO3
Molar mass: 121.136 g·mol−1
Appearance: White crystalline powder
Density: 1.328g/cm3
Melting point: >175-176 °C (448-449 K)
Boiling point: 219 °C (426 °F; 492 K)
Solubility in water: ~50 g/100 mL (25 °C)
Acidity (pKa): 8.07 (conjugate acid)
CAS Number: 77-86-1 (free base), 1185-53-1 (hydrochloride),
6850-28-8 (acetate salt)
EC Number: 201-064-4
Empirical Formula (Hill Notation): C4H11NO3

CAS Number: 77-86-1
Molecular Weight: 121.14
EC Number: 201-064-4
MDL number: MFCD00004679
UNSPSC Code: 41116107
PubChem Substance ID: 329823332
NACRES: NA.24
Molecular Weight: 121.14 g/mol
XLogP3-AA: -2.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 4

Rotatable Bond Count: 3
Exact Mass: 121.07389321 Da
Monoisotopic Mass: 121.07389321 Da
Topological Polar Surface Area: 86.7 Å²
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 54
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Computed by PubChem
Compound Is Canonicalized: Yes
Physical state: Crystalline
Color: White
Odor: Slight, characteristic
Melting point/freezing point: Melting point/range: 169 °C at ca.1.013 hPa
Initial boiling point and boiling range: 288 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: Not applicable
Autoignition temperature: The substance or mixture is not classified as self heating
Decomposition temperature: 143 °C
pH: 10.2 - 10.6 at 6 g/l at 20 °C
Viscosity:
Viscosity, kinematic: Not applicable
Viscosity, dynamic: No data available
Water solubility: 678 g/l at 20 °C - Completely soluble
Partition coefficient: n-octanol/water log Pow: -2.31 at 20 °C

Vapor pressure: < 0.1 hPa at 20 °C
Density: 1.32 g/cm3 at 20 °C - OECD Test Guideline 109
Relative density: 1.32 at 20.4 °C - OECD Test Guideline 109
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: None
Other safety information: Solubility in other solvents: Ethyl acetate at 20 °C -
Slightly soluble
Formula: C4H11NO3

Molecular weight: 121.1350
IUPAC Standard InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2 Copy
InChI version: 1.06
IUPAC Standard InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N Copy
CAS Registry Number: 77-86-1
Formula: C4H11NO3
Molecular weight: 121.14 g/mol
Molecular size: Small
Controlled Substance: No
Precursor: No
Indications: Blood substitutes and perfusion solutions

FIRST AID MEASURES of TROMETHAMINE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of TROMETHAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of TROMETHAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of TROMETHAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of TROMETHAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of TROMETHAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available