TSGD (TETRASODIUM GLUTAMATE DIACETATE)

TSGD (Tetrasodium Glutamate Diacetate) is a biodegradable chelating agent used as a sequestrant and stabilizer in cleaning, personal care, and industrial formulations, and TSGD (Tetrasodium Glutamate Diacetate) is valued for strong binding of hardness ions and transition metals with improved environmental profile compared with traditional EDTA systems.
TSGD (Tetrasodium Glutamate Diacetate) helps control calcium, magnesium, iron, and other metal ions that can reduce surfactant performance, cause haze, catalyze oxidation, or form scale, and TSGD (Tetrasodium Glutamate Diacetate) is widely used in detergents, household and institutional cleaners, personal care products, and water-based formulations where metal control improves stability and cleaning efficiency.
TSGD (Tetrasodium Glutamate Diacetate) is typically supplied as a clear aqueous solution or as a white to off-white powder depending on grade, and TSGD (Tetrasodium Glutamate Diacetate) performance depends on active content, pH, dosage, and the hardness load of the water or formulation.

CAS Number: 51981-21-6 (commonly associated)
EC Number: 257-573-7 (commonly associated)
Molecular Formula: C9H9NNa4O8
Molecular Weight: 351.09 g/mol

Synonyms: TSGD (Tetrasodium Glutamate Diacetate), Tetrasodium Glutamate Diacetate, GLDA-Na4, Tetrasodium GLDA, Glutamic Acid N,N-Diacetic Acid Tetrasodium Salt, GLDA Tetrasodium Salt, Biodegradable Chelating Agent GLDA, TSGD Chelator, Metal Sequestrant GLDA, Hard Water Chelator, GLDA Sequestrant, Tetrasodium Glutamate Diacetate Powder, TSGD, Tetrasodium Glutamate Diacetate, Tetrasodium Glutamate Diacetate Powder, GLDA Tetrasodium Salt, Glutamic Acid Diacetic Acid Tetrasodium Salt, L-Glutamic Acid N,N-Diacetic Acid Tetrasodium Salt, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, Tetrasodium N,N-Bis(carboxymethyl)glutamate, Tetrasodium N,N-Dicarboxymethyl Glutamate, Tetrasodium Glutamate-N,N-Diacetate, Glutamate Diacetate Tetrasodium Salt, Sodium Glutamate Diacetate, Tetrasodium GLDA, GLDA-Na4, GLDA Na4, Tetrasodium L-Glutamate Diacetate, L-GLDA Tetrasodium Salt, L-Glutamic Acid Diacetate Tetrasodium Salt, Tetrasodium Glutamic Acid Diacetate, Tetrasodium Salt of Glutamic Acid Diacetic Acid, N,N-Diacetic Acid Glutamate Tetrasodium Salt, Glutamate N,N-Diacetate Tetrasodium Salt, Biodegradable Chelating Agent GLDA, GLDA Chelating Agent, TSGD Chelating Agent, Tetrasodium Glutamate Diacetate Chelator, Tetrasodium Glutamate Diacetate Sequestrant, Tetrasodium Glutamate Diacetate Complexing Agent, GLDA Sequestrant, GLDA Complexing Agent, GLDA Builder, GLDA Detergent Builder, Tetrasodium Glutamate Diacetate Builder, Tetrasodium Glutamate Diacetate Detergent Additive

APPLICATIONS

TSGD (Tetrasodium Glutamate Diacetate) is used in laundry detergents to bind calcium and magnesium and improve cleaning performance in hard water.
TSGD (Tetrasodium Glutamate Diacetate) is incorporated into liquid detergents to reduce soap scum formation and improve surfactant efficiency.
TSGD (Tetrasodium Glutamate Diacetate) is used in powder detergents to improve builder performance and reduce redeposition in compatible systems.

TSGD (Tetrasodium Glutamate Diacetate) is used in dishwashing formulations to reduce filming and spotting by controlling hardness ions.
TSGD (Tetrasodium Glutamate Diacetate) is incorporated into automatic dishwashing products in selected applications to improve scale control and cleaning consistency.
TSGD (Tetrasodium Glutamate Diacetate) is used in rinse aids in selected formulations to improve clarity and reduce mineral residue.

TSGD (Tetrasodium Glutamate Diacetate) is used in household and institutional cleaners to improve performance in hard water and reduce scale formation.
TSGD (Tetrasodium Glutamate Diacetate) is incorporated into bathroom and kitchen cleaners to bind calcium and prevent re-precipitation of soils.
TSGD (Tetrasodium Glutamate Diacetate) is used in descaling-adjacent cleaners in selected applications to improve mineral control and stability.

TSGD (Tetrasodium Glutamate Diacetate) is used in personal care products to bind trace metals and improve preservative performance and color stability.
TSGD (Tetrasodium Glutamate Diacetate) is incorporated into shampoos and body washes to reduce metal-catalyzed oxidation and reduce discoloration in compatible formulations.
TSGD (Tetrasodium Glutamate Diacetate) is used in creams and lotions in selected applications to improve stability and reduce rancidity of sensitive ingredients.

TSGD (Tetrasodium Glutamate Diacetate) is used in industrial water-based formulations where metal ion control improves stability, reduces precipitation, and improves product appearance.
TSGD (Tetrasodium Glutamate Diacetate) is incorporated into water treatment and cleaning-in-place systems in selected applications to improve hardness control and reduce deposits.
TSGD (Tetrasodium Glutamate Diacetate) is valued because TSGD (Tetrasodium Glutamate Diacetate) provides strong chelation with improved biodegradability, supporting stable, high-performing formulations in hard-water environments.

TSGD (Tetrasodium Glutamate Diacetate) is used as a biodegradable chelating agent in cleaning formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps bind calcium, magnesium, iron, and other metal ions.
TSGD (Tetrasodium Glutamate Diacetate) is used in household detergent formulations.
TSGD (Tetrasodium Glutamate Diacetate) improves cleaning performance in hard-water conditions.

TSGD (Tetrasodium Glutamate Diacetate) is used in automatic dishwashing detergents.
TSGD (Tetrasodium Glutamate Diacetate) helps reduce spotting, filming, and mineral deposits on dishes.
TSGD (Tetrasodium Glutamate Diacetate) is used in laundry detergent formulations.
TSGD (Tetrasodium Glutamate Diacetate) supports soil removal and fabric cleanliness in mineral-rich water.

TSGD (Tetrasodium Glutamate Diacetate) is used in liquid cleaning products.
TSGD (Tetrasodium Glutamate Diacetate) helps stabilize formulations by controlling trace metal impurities.
TSGD (Tetrasodium Glutamate Diacetate) is used in hard-surface cleaners.
TSGD (Tetrasodium Glutamate Diacetate) improves removal of scale, soap scum, and mineral residues.

TSGD (Tetrasodium Glutamate Diacetate) is used in bathroom cleaning formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps remove calcium-based deposits from tiles, sinks, and fixtures.
TSGD (Tetrasodium Glutamate Diacetate) is used in kitchen cleaning products.
TSGD (Tetrasodium Glutamate Diacetate) supports grease removal and mineral deposit control.

TSGD (Tetrasodium Glutamate Diacetate) is used in industrial and institutional cleaning products.
TSGD (Tetrasodium Glutamate Diacetate) improves cleaning efficiency in alkaline and neutral systems.
TSGD (Tetrasodium Glutamate Diacetate) is used in food-processing equipment cleaners.
TSGD (Tetrasodium Glutamate Diacetate) helps remove mineral scale and processing residues.

TSGD (Tetrasodium Glutamate Diacetate) is used in dairy equipment cleaning.
TSGD (Tetrasodium Glutamate Diacetate) helps control milkstone and calcium deposits.
TSGD (Tetrasodium Glutamate Diacetate) is used in beverage plant cleaning systems.
TSGD (Tetrasodium Glutamate Diacetate) supports cleaning of tanks, lines, and filling equipment.

TSGD (Tetrasodium Glutamate Diacetate) is used in bottle-washing formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps prevent redeposition of mineral soils during washing.
TSGD (Tetrasodium Glutamate Diacetate) is used in personal care formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps improve stability by binding trace metal ions.

TSGD (Tetrasodium Glutamate Diacetate) is used in shampoos and body washes.
TSGD (Tetrasodium Glutamate Diacetate) helps improve product clarity and performance in hard water.
TSGD (Tetrasodium Glutamate Diacetate) is used in liquid soaps and cleansing gels.
TSGD (Tetrasodium Glutamate Diacetate) supports formulation stability and prevents metal-catalyzed discoloration.

TSGD (Tetrasodium Glutamate Diacetate) is used in cosmetic creams and lotions.
TSGD (Tetrasodium Glutamate Diacetate) helps protect sensitive ingredients from metal ion effects.
TSGD (Tetrasodium Glutamate Diacetate) is used in textile processing.
TSGD (Tetrasodium Glutamate Diacetate) helps control metal ions during scouring, bleaching, and dyeing.

TSGD (Tetrasodium Glutamate Diacetate) is used in pulp and paper processing.
TSGD (Tetrasodium Glutamate Diacetate) helps stabilize peroxide bleaching systems.
TSGD (Tetrasodium Glutamate Diacetate) is used in water treatment applications.
TSGD (Tetrasodium Glutamate Diacetate) supports control of hardness ions and trace metals.

TSGD (Tetrasodium Glutamate Diacetate) is used in agricultural formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps keep micronutrient metals soluble in compatible systems.
TSGD (Tetrasodium Glutamate Diacetate) is used in fertilizer formulations.
TSGD (Tetrasodium Glutamate Diacetate) supports availability of chelated trace elements.

TSGD (Tetrasodium Glutamate Diacetate) is used in metal cleaning formulations.
TSGD (Tetrasodium Glutamate Diacetate) helps remove oxide residues and metal contamination.
TSGD (Tetrasodium Glutamate Diacetate) is used in environmentally preferred cleaning products.
TSGD (Tetrasodium Glutamate Diacetate) supports replacement of less biodegradable chelating agents in many formulations.

TSGD (Tetrasodium Glutamate Diacetate) is used in formulations requiring strong chelation and improved environmental profile.

DESCRIPTION

TSGD (Tetrasodium Glutamate Diacetate) is the tetrasodium salt of glutamic acid diacetic acid, and TSGD (Tetrasodium Glutamate Diacetate) is a polycarboxylate-type chelator derived from amino acid chemistry.
TSGD (Tetrasodium Glutamate Diacetate) forms stable complexes with calcium, magnesium, and many transition metals, and this reduces scale formation and improves cleaning performance by keeping metals in solution.
TSGD (Tetrasodium Glutamate Diacetate) chelation performance depends on pH, and higher pH generally increases complexation strength and improves hardness control in alkaline cleaning systems.

TSGD (Tetrasodium Glutamate Diacetate) is often selected as an alternative to EDTA because TSGD (Tetrasodium Glutamate Diacetate) is readily biodegradable under many conditions, supporting improved environmental profile for formulated products.
TSGD (Tetrasodium Glutamate Diacetate) can improve stability of formulations by reducing metal-catalyzed oxidation and discoloration, and this supports better fragrance and color stability.
TSGD (Tetrasodium Glutamate Diacetate) should be used according to applicable regulations and good manufacturing practices for the target market and product category.

TSGD (Tetrasodium Glutamate Diacetate) is typically supplied as an alkaline solution or powder, and active content and sodium contribution must be considered in formulation design.
TSGD (Tetrasodium Glutamate Diacetate) should be stored in tightly closed containers to prevent contamination and water loss for solutions.
TSGD (Tetrasodium Glutamate Diacetate) should be protected from excessive heat and extreme conditions that can affect stability and handling.

TSGD (Tetrasodium Glutamate Diacetate) is a tetrasodium salt of glutamic acid diacetate.
TSGD (Tetrasodium Glutamate Diacetate) is a biodegradable aminocarboxylate chelating agent.
TSGD (Tetrasodium Glutamate Diacetate) is commonly used as an alternative to traditional chelants such as EDTA.
TSGD (Tetrasodium Glutamate Diacetate) is valued for strong metal-binding performance.

TSGD (Tetrasodium Glutamate Diacetate) is typically supplied as an aqueous solution or solid powder depending on grade.
TSGD (Tetrasodium Glutamate Diacetate) is highly soluble in water.
TSGD (Tetrasodium Glutamate Diacetate) is effective over a broad pH range.
TSGD (Tetrasodium Glutamate Diacetate) works by forming stable complexes with multivalent metal ions.

TSGD (Tetrasodium Glutamate Diacetate) can bind calcium, magnesium, iron, copper, manganese, and other trace metals.
TSGD (Tetrasodium Glutamate Diacetate) helps reduce problems caused by water hardness.
TSGD (Tetrasodium Glutamate Diacetate) helps prevent metal-catalyzed degradation of sensitive formulation ingredients.
TSGD (Tetrasodium Glutamate Diacetate) can improve stability, clarity, and cleaning efficiency in aqueous systems.

TSGD (Tetrasodium Glutamate Diacetate) is compatible with many surfactants, builders, alkaline agents, and formulation additives.
TSGD (Tetrasodium Glutamate Diacetate) performance depends on pH, dosage, temperature, and metal ion concentration.
TSGD (Tetrasodium Glutamate Diacetate) is selected when biodegradability and chelation strength are both important.
TSGD (Tetrasodium Glutamate Diacetate) can support phosphate-free and environmentally conscious formulation strategies.

TSGD (Tetrasodium Glutamate Diacetate) should be stored in tightly closed containers.
TSGD (Tetrasodium Glutamate Diacetate) should be protected from contamination and extreme storage conditions.
TSGD (Tetrasodium Glutamate Diacetate) should be handled according to the supplier safety data sheet.
TSGD (Tetrasodium Glutamate Diacetate) may irritate eyes or skin depending on concentration and exposure conditions.

TSGD (Tetrasodium Glutamate Diacetate) quality may be defined by active content, pH, color, density, and chelation value.
TSGD (Tetrasodium Glutamate Diacetate) is important in cleaning, personal care, agriculture, textile, paper, and water treatment applications.
TSGD (Tetrasodium Glutamate Diacetate) is valued for combining effective sequestration with improved environmental compatibility.
TSGD (Tetrasodium Glutamate Diacetate) supports modern formulations requiring reliable metal ion control.

TSGD (Tetrasodium Glutamate Diacetate) is selected when high-performance biodegradable chelation is required.

PROPERTIES

Chemical Formula: C9H9NNa4O8
Molecular Weight: 351.09 g/mol
Common Name: TSGD (Tetrasodium Glutamate Diacetate); GLDA-Na4
Chemical Type: Biodegradable chelating agent; sequestrant; builder (formulation dependent)
Appearance: Clear aqueous solution or white to off-white powder (grade dependent)
Odor: Mild characteristic odor
Solubility: Highly soluble in water
Chelation: Strong binding for Ca, Mg, Fe, Cu, Mn, and other metal ions
pH (solution): Alkaline (grade dependent; often supplied at high pH)
Stability: Stable under recommended storage; compatibility depends on formulation pH and surfactant system
Storage Temperature: 5–30°C, tightly closed
Shelf Life: Typically 12–36 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust or mists are inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during powder handling and aerosols during spraying.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a significant amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses for bulk handling.
Avoid splashing into eyes and avoid prolonged skin contact, especially for alkaline solutions.
Use clean equipment and good hygiene practices to prevent contamination.

Ventilation:
Use general ventilation for normal handling.
Use local exhaust where dust may be generated during powder transfer.
Avoid aerosol formation in enclosed spaces without adequate airflow.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from contamination and extreme heat; prevent freezing for liquid grades if applicable.
Keep away from strong acids because acidification can change performance and can release heat in neutralization.

Spill and Leak Procedures:
Contain spill and absorb with inert material for liquids.
Sweep up spilled powder and avoid dust generation for solid grades.
Dispose of waste according to local regulations and facility procedures.

Handling Precautions:
Optimize dosage because TSGD (Tetrasodium Glutamate Diacetate) influences hardness control, stability, and sodium load in the final formulation.
Match pH and system design because chelation strength and compatibility depend on pH and surfactant interactions.
Rotate stock using FIFO practices to maintain consistent quality and predictable chelation performance.