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TYLOSE MHB 3000 P2 is used as a liquid loss additive. Among the various solutions required for drilling, completion, cementing and crushing, TYLOSE MHB 3000 P2 provides good uidity and stability to mud.
TYLOSE MHB 3000 P2 is used as a binder, thickener, stabilizer and dispersant in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 stabilizes the latex paint and increases the viscosity of the component.
CAS Number: 9004-62-0
Molecular Formula: C29H52O21
EINECS Number: 618-387-5
Synonyms: 9004-62-0, Cellulose, 2-hydroxyethyl ether, 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4, hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol, Hydroxyethyl-cellulose
SCHEMBL23306563, DTXSID60873934, CWSZBVAUYPTXTG-UHFFFAOYSA-N, DA-643212-hydroxyethylcelluloseether, ah15, aw15(polysaccharide), aw15[polysaccharide], bl15, cellosize, The blood coHydroxyethyl cellulose etherngeals the appearance board, 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
TYLOSE MHB 3000 P2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +.
Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid.
The role of thickener in the aqueous ink is thickened.
The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink.
Thickening agent is a TYLOSE MHB 3000 P2-based material and (or) polyvinyl alcohol substances.
TYLOSE MHB 3000 P2 substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Hydroxyethyl cellulose and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic cellulose ether derived from natural polymers such as wood pulp or cotton.
Specifically, TYLOSE MHB 3000 P2 is classified as methyl hydroxyethyl cellulose (MHEC), known for its high degree of etherification.
This chemical modification enhances its solubility and functional properties, making it a versatile additive in various industrial applications.
In the construction industry, TYLOSE MHB 3000 P2 serves as a highly efficient water retention agent, adhesive, film-forming agent, and stabilizer.
Its inclusion in cement-based products, such as tile adhesives and single-coat applications, ensures rapid consistency development, high water retention, and improved workability, while maintaining moderate sag resistance and water demand.
These characteristics contribute to the durability and performance of construction materials.
In the paint and coatings sector, TYLOSE MHB 3000 P2 is valued for its ability to enhance gloss appearance, pigment compatibility, and water retention.
TYLOSE MHB 3000 P2 imparts moderate anti-splash properties, pseudoplasticity, thickening effects, and wet rubbing resistance, making it particularly suitable for interior paints, solid paints, exterior paints, powder paints, cement paints, glazes, and distempers.
TYLOSE MHB 3000 P2s versatility allows for tailored modifications to meet specific customer requirements, ensuring optimal performance across different formulations.
TYLOSE MHB 3000 P2 is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water.
Insoluble in common organic solvents.
Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding.
Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte.
TYLOSE MHB 3000 P2 is used as a binder, thickener, stabilizer TYLOSE MHB 3000 and dispersant in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 has good compatibility with other ingredients in the components such as pigments, excipients, llers and salts.
The high viscosity TYLOSE MHB 3000 P2 is mainly used as an adhesive for nishing and nishing uids in oil drilling.
TYLOSE MHB 3000 P2 Provides easy application with its shear strength and binding eect in products with its feature of holding water in its structure.
TYLOSE MHB 3000 P2 Helps create movies. TYLOSE MHB 3000 P2 is used as a thickener in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 is prepared from alkali cellulose and ethylene oxide.
It may be noted that the hydroxyethyl group itself can react with ethylene oxide so that side-chains of varying length may be present in the product.
Commercial materials generally contain between 1.4 and 2.0 ethylene oxide residues per glucose residue and have a degree of substitution of about 0.8-1.0.
TYLOSE MHB 3000 P2 in the latex paint composition prevents the gel from gelling, contributes to its dispersion, stabilizes the latex paint and increases the viscosity of the component.
TYLOSE MHB 3000 P2 has good compatibility with other materials such as pigments, auxiliary substances, llers and salts in its components.
Coatings thickened with TYLOSE MHB 3000 P2 have good rheology at various cutting speeds and are pseudoplastic.
TYLOSE MHB 3000 P2 is also named as methyl hydroxyethyl cellulose (MHEC).
TYLOSE MHB 3000 P2 is a white, grayish-white, or yellowish-white granules.
TYLOSE MHB 3000 P2 is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose.
TYLOSE MHB 3000 P2 is produced from a natural renewable polymer such as wood pulp or cotton.
TYLOSE MHB 3000 P2 can be used as a highly ecient water retention agent, adhesives and lm-forming agent, stabilizer, etc.
TYLOSE MHB 3000 P2 is widely used in dierent industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.
TYLOSE MHB 3000 P2 can be modied according to customers’ requirement and still have its good anti-sagging property and good workability after modication.
TYLOSE MHB 3000 P2 is used by the oil and gas industry for a variety of applications such as rheology modication in uids for drilling and completion of oil and gas wells.
TYLOSE MHB 3000 P2 is well suited for dierent oileld applications
In addition, TYLOSE MHB 3000 P2 is used in hydraulic fracturing and is an eective uid loss additive in well cements.
TYLOSE MHB 3000 P2 is compatible with most additives such as biocides, antifoam agents, oxygen scavengers, uid loss control additives and retarders.
As a naturally derived polymer, TYLOSE MHB 3000 P2 is readily biodegradable.
TYLOSE MHB 3000 P2 grades are used as a viscosity agent in drilling uids, especially heavy brines for nishing and working operations.
TYLOSE MHB 3000 P2 is perfectly suited for the viscosity of these liquids as it forms stable solutions with high salt concentrations.
The use of TYLOSE MHB 3000 P2 provides other benets such as higher drilling speeds and increased oil production and can be broken down easily with chemical and enzyme based breakers.
The selection of TYLOSE MHB 3000 P2 grades depends on the application and requirements, the most commonly used grades are the
TYLOSE MHB 3000 P2 grades.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic, chemically modied hydroxyethyl cellulose in the form of granules with special etherication.
TYLOSE MHB 3000 P2 exhibits increased biostability, very high gloss appearance and pigment compatibility, excellent anti-splash properties, low pseudoplasticity, moderate thickening eects and water retention and high wet scrubbing resistance.
This grade of hydroxyethyl cellulose is particularly well suited for use in interior paint applications.
TYLOSE MHB 3000 P2 is a water soluble, nonionic, highly etheried hydroxyethyl cellulose powder.
TYLOSE MHB 3000 P2 shows increased biostability, rapid consistency development, high gloss appearance, pigment compatibility and water retention, low sag resistance and water demand, and moderate anti-splash properties, thickening eects and inuence on cement hydration.
This hydroxyethyl cellulose grade is particularly well suited for use in tinter, emulsion grouting and rubber glove applications.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic, highly etheried hydroxyethyl cellulose powder.
TYLOSE MHB 3000 P2 exhibits increased biostability, moderate thickening eects, high solution clarity, rapid consistency development, high gloss appearance and pigment compatibility, and low sag resistance and water demand.
This grade of hydroxyethyl cellulose is ideal for use in emulsion decorative plasters, glazes, powder and solid paints, colorants, liquid detergents and toilet cleaners / wc gels.
Melting point: 288-290 °C (dec.)
Density: 0.75 g/mL at 25 °C (lit.)
Bulk density: 350 kg/m³
Storage temp.: 2-8°C
Solubility: H₂O: ≤5 wt. % at 20 °C
Form: Powder
Color: Light brown powder
Odor: Odorless
pH: pH (20g/L, 25℃): 5.0～8.0
Biological source: Rabbit
Viscosity: ~270 mPas at 20°C
Water Solubility: Almost transparency
Merck: 14,4673
TYLOSE MHB 3000 P2 is soluble in hot or cold water, and does not precipitate at high temperature or boiling, so it has a wide range of solubility and viscosity characteristics, as well as non-thermal gelling properties.
TYLOSE MHB 3000 P2 is a non-ionic polymer material , can coexist with a wide range of other water-soluble polymers, surfactants, and salts, and is an excellent colloidal thickener for high-concentration dielectric solutions.
The water retention capacity of hydroxyethyl cellulose is twice that of methyl cellulose, and it has better flow regulation; the dispersing ability of hydroxyethyl cellulose is comparable to that of methyl cellulose and hydroxypropyl methyl cellulose
The specific dispersing ability is the worst, but the protective colloid ability is the strongest.
A purified form of cellulose is reacted with sodium hydroxide to produce a swollen alkali cellulose, which is chemically more reactive than untreated cellulose.
The alkali cellulose is then reacted with ethylene oxide to produce a series of hydroxyethyl cellulose ethers.
The manner in which ethylene oxide is added to cellulose can be described by two terms, the degree of substitution (DS) and the molar substitution (MS).
The DS designates the average number of hydroxyl positions on the anhydroglucose unit that have been reacted with ethylene oxide.
Since each anhydroglucose unit of the cellulose molecule has three hydroxyl groups, the maximum value for DS is 3.
TYLOSE MHB 3000 P2 is defined as the average number of ethylene oxide molecules that have reacted with each anhydroglucose unit.
Once a hydroxyethyl group is attached to each unit, it can further react with additional groups in an end-to-end formation.
This reaction can continue and there is no theoretical limit for MS.
TYLOSE MHB 3000 P2 prevents the pigment from gelling in the latex paint composition, contributes to its dispersion, stabilizes the latex paint and increases the viscosity of the component.
TYLOSE MHB 3000 P2 has good compatibility with other ingredients in the components such as pigments, excipients, llers and salts.
When the pH of the TYLOSE MHB 3000 P2 water solution is between 2 and 12, the viscosity is stable.
If TYLOSE MHB 3000 P2 exceeds this range, acidic or alkaline oxidative degradation will occur and viscosity will decrease.
TYLOSE MHB 3000 P2 It has thickening feature.
TYLOSE MHB 3000 P2 has the adhesive feature.
TYLOSE MHB 3000 P2 has the ability to form dispersion.
TYLOSE MHB 3000 P2 has lm formation and suspension properties.
The viscosity of the TYLOSE MHB 3000 P2 aqueous solution decreases as the temperature increases, and the viscosity can be recovered when the temperature drops to the original temperature.
TYLOSE MHB 3000 P2 If there is no high salt concentration, when the solution is heated to boiling point, no gel or precipitate is formed; ie TYLOSE MHB 3000 P2 is very resistant to temperature.
TYLOSE MHB 3000 P2 aqueous solution is a nonionic system and can be used for other water soluble polymers, surfactants, salts, etc. can be found together with.
Therefore TYLOSE MHB 3000 P2 is widely used in the daily chemical industry TYLOSE MHB 3000 P2 is used as a binder in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 is used as a thickener in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 is used as a stabilizer in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 is used as a dispenser in toothpaste, detergent and cosmetic products.
Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin.
The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin.
TYLOSE MHB 3000 P2 is insoluble in most organic solvents.
TYLOSE MHB 3000 P2 is incompatible with zein and partially compatible with the following water-soluble compounds: casein; gelatin; methylcellulose; polyvinyl alcohol, and starch.
TYLOSE MHB 3000 P2 can be used with a wide variety of watersoluble antimicrobial preservatives.
However, sodium pentachlorophenate produces an immediate increase in viscosity when added to hydroxyethyl cellulose solutions.
TYLOSE MHB 3000 P2 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions.
For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate.
Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate.
Natrosol 150 is generally more tolerant of dissolved salts than is Natrosol 250.
TYLOSE MHB 3000 P2 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions.
TYLOSE MHB 3000 P2 is not currently approved for use in food products in Europe or the USA, although it is permitted for use in indirect applications such as packaging.
This restriction is due to the high levels of ethylene glycol residues that are formed during the manufacturing process.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic, modied methyl hydroxyethyl cellulose powder with standard etherication.
TYLOSE MHB 3000 P2 shows very fast consistency development, moderate sag resistance and water demand, very high water retention and low impact on cement hydration.
This grade of methyl hydroxyethyl cellulose is particularly well suited for use in single coat cement, cement tile adhesive, gypsum mounting binder and gypsum glaze compound applications.
TYLOSE MHB 3000 P2 is also named as methyl hydroxyethyl cellulose (MHEC).
TYLOSE MHB 3000 P2 is a white, grayish-white, or yellowish-white granules.
TYLOSE MHB 3000 P2 is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose.
Beyond construction and coatings, TYLOSE MHB 3000 P2 finds applications in oil drilling, pharmaceuticals, and other industrial processes.
Its surface-active properties enable it to function effectively as a dispersant, protective agent, and emulsifier in aqueous solutions.
Furthermore, it exhibits increased biostability, rapid consistency development, high solution clarity, thermal stability, and low sag resistance and water demand, making it ideal for use in emulsion tile adhesives, exterior and interior paints, silicone resin paints, drilling fluids, non-woven fabrics, and wash fluids.
These attributes underscore its role in enhancing the efficiency and quality of various industrial applications.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic hydroxyethyl cellulose powder with standard etherication.
TYLOSE MHB 3000 P2 exhibits a high gloss appearance, pigment compatibility and water retention, and moderate anti-splash properties, pseudoplasticity, thickening eects and wet rubbing resistance.
This grade of hydroxyethyl cellulose is particularly well suited for use in silicate and solid paint applications.
TYLOSE MHB 3000 P2 is a water-soluble, non-ionic, highly etheried methyl hydroxypropyl cellulose in granule form.
TYLOSE MHB 3000 P2 provides good protective colloidal eects and particle size control.
This type of methyl hydroxypropyl cellulose is particularly well suited for use in rubber glove, seed coating and PVC suspension polymerization applications
Production methods Of TYLOSE MHB 3000 P2:
Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give TYLOSE MHB 3000 P2.
The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour.
Squeezed water containing soda to 1: 2.8, pulverized.
Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle.
Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Hydroxyethyl cellulose was obtained.
The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging.
Then washed with water, centrifugal dewatering, dryed, milled to obtain TYLOSE MHB 3000 P2.
Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300.
The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze.
Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into.
In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Hydroxyethyl cellulose.
The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Hydroxyethyl cellulose.
Uses Of TYLOSE MHB 3000 P2:
TYLOSE MHB 3000 P2 is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride.
Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry.
Glazing in ceramic industry and toothpaste binder.
Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent.
TYLOSE MHB 3000 P2 is used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid.
Also can be used for filtrate reducer of oil well cement.
Cross-linking with the polyvalent metal ions into a gel.
As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion.
Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides.
There are many uses in oil exploitation and machinery industry.
As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc.
TYLOSE MHB 3000 P2 is a thickener, protective colloid, binder, stabilizer, and suspending agent.
TYLOSE MHB 3000 P2 is obtained from wood pulp Copyright 2014 Cengage Learning.
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TYLOSE MHB 3000 P2 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations.
TYLOSE MHB 3000 P2 is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.
It is present in lubricant preparations for dry eye, contact lens care, and dry mouth.
The concentration of TYLOSE MHB 3000 P2 used in a formulation is dependent upon the solvent and the molecular weight of the grade.
TYLOSE MHB 3000 P2 is also widely used in cosmetics.
TYLOSE MHB 3000 P2 Used in paint removers.
TYLOSE MHB 3000 P2 Used as chang fuel thickener.
TYLOSE MHB 3000 P2 is used as a binder, thickener, stabilizer and dispersant in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 Provides easy application with its shear strength and binding eect in products with its feature of holding water in its structure.
High viscosity TYLOSE MHB 3000 P2 is mainly used as an adhesive for nishing and nishing uids in oil drilling.
Low viscosity TYLOSE MHB 3000 P2 is used as a uid loss additive.
Among the various solutions required for drilling, nishing, cementing and crushing, TYLOSE MHB 3000 P2 provides good uidity and stability to the mud.
TYLOSE MHB 3000 P2 is used as binder, thickener, stabilizer and dispersant in toothpaste, detergent and cosmetic products.
TYLOSE MHB 3000 P2 is a highly versatile methyl hydroxyethyl cellulose (MHEC) that serves as a crucial additive in multiple industries, including construction, paints and coatings, pharmaceuticals, and oil drilling.
Due to its water retention, thickening, adhesion, and stabilizing properties, it significantly enhances the performance, workability, and durability of various products.
In the construction industry, TYLOSE MHB 3000 P2 is widely used as a key ingredient in cement-based formulations, such as tile adhesives, plasters, self-leveling compounds, and mortars. Its excellent water retention capability ensures optimal hydration of cement and gypsum, preventing premature drying and improving workability.
Additionally, it enhances adhesion strength, reduces material sagging, and allows for smoother application, leading to superior bonding and durability of the final structures.
In the paints and coatings industry, TYLOSE MHB 3000 P2 plays an essential role in improving the viscosity, consistency, and stability of water-based paints.
It enhances paint application by increasing viscosity, preventing pigment settling, and promoting even film formation.
TYLOSE MHB 3000 P2 contributes to excellent water retention, which is crucial in preventing cracks and ensuring long-lasting, high-quality finishes.
This cellulose ether is particularly beneficial in interior and exterior wall paints, silicone resin coatings, cement paints, and powder coatings, as it provides better coverage, enhanced resistance to splattering, and improved scrub resistance.
In oil drilling applications, TYLOSE MHB 3000 P2 functions as a thickening and stabilizing agent in drilling fluids and wash solutions.
TYLOSE MHB 3000 P2 helps control fluid viscosity, reduces fluid loss, and improves suspension properties, ensuring efficient drilling operations.
By preventing excessive water loss and maintaining the stability of drilling mud, it enhances the effectiveness of wellbore stabilization and protects drilling equipment from clogging and wear.
In the pharmaceutical and personal care industries, TYLOSE MHB 3000 P2 is used as a binder, film-forming agent, and viscosity modifier in tablet formulations, gels, lotions, and creams.
TYLOSE MHB 3000 P2s biocompatibility and non-toxic nature make it suitable for pharmaceutical applications where controlled release, smooth texture, and stability are essential.
TYLOSE MHB 3000 P2 highlight its importance as a functional ingredient across various industries.
Its ability to improve workability, water retention, adhesion, and viscosity makes it a critical component in construction materials, paints, drilling fluids, and pharmaceutical formulations, ultimately contributing to enhanced product performance and efficiency.
Storage Of TYLOSE MHB 3000 P2:
TYLOSE MHB 3000 P2 powder is a stable though hygroscopic material.
Aqueous solutions of hydroxyethyl cellulose are relatively stable at pH 2–12 with the viscosity of solutions being largely unaffected.
However, solutions are less stable below pH 5 owing to hydrolysis.
At high pH, oxidation may occur.
Increasing the temperature reduces the viscosity of aqueous TYLOSE MHB 3000 P2 solutions.
However, on cooling, the original viscosity is restored.
Solutions may be subjected to freeze–thawing, high-temperature storage, or boiling without precipitation or gelation occurring.
TYLOSE MHB 3000 P2 is subject to enzymatic degradation, with consequent loss in viscosity of its solutions.
Enzymes that catalyze this degradation are produced by many bacteria and fungi present in the environment.
For prolonged storage, an antimicrobial preservative should therefore be added to aqueous solutions.
Aqueous solutions of hydroxyethyl cellulose may also be sterilized by autoclaving.
TYLOSE MHB 3000 P2 powder should be stored in a well-closed container, in a cool, dry place.
Safety Profile Of TYLOSE MHB 3000 P2:
TYLOSE MHB 3000 P2 is primarily used in ophthalmic and topical pharmaceutical formulations.
It is generally regarded as an essentially nontoxic and nonirritant material.
Acute and subacute oral toxicity studies in rats have shown no toxic effects attributable to hydroxyethyl cellulose consumption, the hydroxyethyl cellulose being neither absorbed nor hydrolyzed in the rat gastrointestinal tract.
However, although used in oral pharmaceutical formulations, TYLOSE MHB 3000 P2 has not been approved for direct use in food products.
Glyoxal-treated TYLOSE MHB 3000 P2 is not recommended for use in oral pharmaceutical formulations or topical preparations that may be used on mucous membranes.
TYLOSE MHB 3000 P2 is also not recommended for use in parenteral products.
