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CAS Number: 32289-58-0
Synonyms:
Polihexanide
Poly(hexamethylenebiguanide)hydrochloride
Poly(hexamethylenediguanide)hydrochloride
PHMB
Chemical Profile:
Chemical Family: Biguanides
Functions: Anti-Microbial Agent, Dispersant
Physical Form: Aqueous solution of PHMB (20% w/w active agent content)
pH Value (25°C): 4.0 - 4.5
Viscosity (at 25°C): 5 mPas
Boiling Point: 102 °C
Density (at 25°C): 1.04
Flash Point: Boils without flashing
Odor: Low Characteristic
Antimicrobial Properties:
VANTOCIL IB has a non-specific mode of biocidal action which means that bacterial resistance is very unlikely to occur . It is effective and stable over pH range 1-11 .
Minimum Inhibitory Concentrations (MIC) :
Micro-organism, Strain No., VANTOCIL IB (ppm product)
Bacteria, ,
Bacillus subtilis, NCIB 3610, 1.5
Enterobacter cloacae, NCIB 8271, 40
Escherichia coli 0157:H7, NCTC 12900, 80
Legionella pneumophila, -, 5
Listeria monocytogenes, ATCC 15313, 30
Proteus vulgaris, NCTC 4175, 40
Pseudomonas aeruginosa, ATCC 15442, 40
Pseudomonas putida, -, 25
Salmonella choleraesius, ATCC 13311, 120
Salmonella typhimurium, ATCC 14028, 160
Staphylococcus aureus, ATCC 6538, 30
Streptococcus faecalis, -, 5
Streptococcus lactis, NCTC 7944, 20
Yeasts, ,
Candida albicans, ATCC 10231, 300
Rhodotorula rubra, NCYC 1659, 7.5
Saccharomyces cerevisiae, ATCC 9763, 300
Amoeba, ,
Acanthamoeba polyphaga, -, 5
Applications :
VANTOCIL IB Antimicrobial is used in several industries, including home care and institutional and industrial applications:
Home Care Sector:
Air care products
Carpet and upholstery cleaners
Dishwashing formulations
Laundry and fabric care products
Surface care formulas
Institutional and Industrial Care:
Vehicle and machinery upkeep
Institutional and catering sanitation
Industrial cleaning
Food facility cleaning and sanitization
Specific Application Areas Include :
Hospitals
Institutions
Veterinary establishments
Dairies
Milking parlors
Poultry hatcheries
Food processing plants
Breweries
Pasteurisers in canned food & beverage bottling plants
Yogurt fermentation
Air-conditioning units
Cheese molds
Beer glass cleaners
Recommended Use Levels :
Application Area, % VANTOCIL IB (w/w) in sanitiser use solution
Disinfection of pre-cleaned solid surfaces (Hospitals, Food Processing, Veterinary establishments, Poultry hatcheries), 0.1-0.2
Water treatment applications (Air conditioning), 0.01-0.1
Fermentation equipment (Yogurt, Cheese molds), 0.3-0.5
Acid descaler sanitiser (Milking parlors, Breweries), 0.4-0.7
Tunnel pasteurization (Canning and bottling plants), 0.005-0.01
Compatibility :
Compatible with: Nonionic surfactants, glycols, glycol ethers, most strong acids, and common chelating agents such as EDTA, NTA, IDS
Limited compatibility with: Anionic surfactants, strong alkalis, complex phosphates, and strong oxidisers
Foaming Properties:
Has significantly less tendency to foam than quaternary ammonium compounds. PHMB is not surface active .
Regulatory Compliance :
The components of VANTOCIL IB Antimicrobial are in compliance with:
EINECS (European Union)
TSCA (USA)
ACOIN/AICS (Australia)
ENCS (Japan)
DSL (Canada)
Korean Inventory
Certifications: Design for Environment (DfE), EPA Registered, Halal, IECIC (China), ISO 9001
Storage:
Stable under normal conditions of storage down to 0°C. If frozen, allow to thaw at room temperature and stir thoroughly before use. Active agent is heat-stable and non-volatile
SAFETY INFORMATION ABOUT VANTOCIL IB
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
