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VANTOCIL IB

Vantocil IB can be used as fungicide and is generally applied as swimming pool bactericide, preservative, all-purpose cleanser, and sanitizer.
Vantocil IB is used in hygiene and sanitation products, sometimes in contact-lens solutions, personal care lines, textiles, swimming pool sanitizers (e.g., Baquacil brand), and other consumer hygiene products containing PHMB in controlled amounts.
Vantocil IB is used primarily as a broad-spectrum bactericide and antimicrobial preservative in many industrial, commercial, and consumer applications.


CAS Number: 27083-27-8
(other registry numbers may appear in databases due to polymer chain length variation, but this is the most commonly referenced CAS)
EC (EINECS) Number: 923-111-4
Active substance: Poly(hexamethylene biguanide) hydrochloride (PHMB)
Molecular Formula: Not fixed
(PHMB is a polymeric substance; therefore, it does not have a single defined molecular formula)
Molecular Weight: Not fixed / variable
(Typical number-average molecular weight is often reported in the range of ~2,000–5,000 g/mol, depending on polymer chain length, but it is not a single exact value)

SYNONYMS:
Poly(hexamethylene biguanide) hydrochloride, PHMB, polyhexanide, polyhexamethylene biguanide, polyhexamethylene guanide hydrochloride, poly(iminocarbonimidoyliminocarbonimidoyliminohexamethylene) hydrochloride, polih exanide, polihexanidum, Cosmoquil CQ, Reputex 20, Baquacil, Vantocil, Vantocil TG, Polihexanide, Poly(hexamethylenebiguanide)hydrochloride, Poly(hexamethylenediguanide)hydrochloride

Vantocil IB has been shown to be very effective against Mycobacterium smegmatis and Mycobacterium intracellularis responsible for tuberculosis in pigs.
Vantocil IB has also been shown to be effective at eradicating Salmonella pullorum, Salmonella typhimurium, Heamophilus gallinarum, Mycoplasma synoviae and pathogenic E.coli, which are responsible for white diarrhoea, respiratory disease and colibacillosis in chickens.


Vantocil IB is a commercial antimicrobial product based on poly(hexamethylene biguanide) hydrochloride, a cationic polymer belonging to the biguanide chemical family.
Vantocil IB is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.


Vantocil IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).
Vantocil IB is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.


Vantocil IB is a branded antimicrobial/disinfectant product widely used in industrial and institutional settings.
The key antimicrobial component of Vantocil IB is poly(hexamethylene biguanide) hydrochloride (PHMB) — a cationic polymer from the biguanide family which exerts antimicrobial effects by interacting with microbial membranes and destabilizing cellular integrity.


Vantocil IB is an aqueous solution.
Vantocil IB is a highly effective preservative for use in a wide variety of applications including oil-in-water and water-in-oil emulsions, industrial reagents, silicone systems, cellulose solutions and oil recovery systems.


Vantocil IB is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.
Vantocil IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).
Vantocil IB has a non-specific mode of biocidal action which means that bacterial resistance is very unlikely to occur.


Vantocil IB is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.
Vantocil IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).
Vantocil IB is an aqueous solution of the powerful antibacterial preservative poly(hexamethylene biguanide) hydrochloride [PHMB], an active offering broad pH tolerance, low foam and good heat stability.


Vantocil IB is a broad spectrum, fast acting bactericide for disinfectants and sanitizers in industrial, institutional, agricultural, food, beverage and domestic disinfection applications.
Vantocil IB is effective in a wide range of industrial disinfection applications, primarily as a solid surface dispersant.


Application areas of Vantocil IB include hospitals, institutions, veterinary establishments, dairies, milking parlors, and other food processing plants.
Vantocil IB is a broad-spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.


Vantocil IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).
Vantocil IB is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.

USES and APPLICATIONS of VANTOCIL IB:
Vantocil IB is effective in a wide range of industrial disinfection applications, primarily as a solid surface disinfectant.
Application areas of Vantocil IB include: Hospitals, Institutions, Veterinary establishments, Dairies, Milking parlors, Poultry hatcheries, Food processing plants, Breweries, Pasteurisers in canned food & beverage bottling plants, Yogurt fermentation, Air-conditioning units, Cheese molds, and Beer glass cleaners.


Long-acting sanitizer; Vantocil IB is broad-spectrum antibacterial and able to kill gram-positive bacteria, gram-negative bacteria, fungi, and saccharomycetes.
Vantocil IB can be used as fungicide and is generally applied as swimming pool bactericide, preservative, all-purpose cleanser, and sanitizer.


Unlike low-molecular-weight disinfectants, Vantocil IB is a polymeric substance, which gives it unique performance characteristics such as prolonged antimicrobial activity and strong affinity for negatively charged surfaces.
Because of its polymeric nature, Vantocil IB does not volatilize and remains effective over extended contact periods.


The antimicrobial performance of Vantocil IB is linked to its interaction with microbial cell membranes.
The positively charged biguanide groups bind to negatively charged components of microbial membranes, leading to membrane destabilization and loss of cellular integrity.


This mechanism allows Vantocil IB to perform effectively at relatively low concentrations compared to many conventional disinfectants.
From a formulation perspective, Vantocil IBB is valued for its stability in aqueous systems.
Vantocil IB maintains activity over a broad pH range and shows good resistance to degradation under normal processing temperatures.


These properties make Vantocil IB suitable for use in liquid formulations where long shelf life and consistent performance are required.
Vantocil IB is also compatible with many surfactants, polymers, and formulation additives, which simplifies its incorporation into complex product systems.


In industrial and institutional environments, Vantocil IB is commonly used in surface hygiene products, equipment sanitation solutions, and preservation of water-based systems.
Vantocil IB is especially useful in applications where microbial growth can compromise product quality, system hygiene, or material integrity.


In addition, Vantocil IB is used as an in-can preservative to protect formulations such as coatings, adhesives, emulsions, and cleaning products from microbial spoilage during storage.
Another notable characteristic of Vantocil IB is its low odor profile and non-volatile behavior, which improve user comfort in indoor applications.


Vantocil IB's effectiveness in both hard and soft water further enhances its versatility across different geographic and industrial settings.
Because Vantocil IB is supplied as an aqueous solution, it can be easily diluted and dosed with standard equipment, supporting precise and reproducible use in manufacturing and sanitation processes.


Overall, Vantocil IB is considered a technically robust antimicrobial solution that combines polymeric stability, formulation flexibility, and reliable performance across a wide range of industrial and commercial hygiene applications.
Specialized Applications: Vantocil IB is used in hygiene and sanitation products, sometimes in contact-lens solutions, personal care lines, textiles, swimming pool sanitizers (e.g., Baquacil brand), and other consumer hygiene products containing PHMB in controlled amounts.


Vantocil IB is used primarily as a broad-spectrum bactericide and antimicrobial preservative in many industrial, commercial, and consumer applications.
Vantocil IB, as a class, is used globally in many sectors due to its broad-spectrum biocidal action, chemical stability, pH tolerance, and compatibility with various formulation systems.


Vantocil IB can be used alone or in combination with other biocides to create products for a wide range of disinfection applications.
Considerable data exists which provides a measure of the intrinsic anti-microbial activity of Vantocil IB, generated via European suspension test protocols relevant to application in Food, Industrial, Domestic and Institutional Hygiene.


Vantocil IB's activity has been further demonstrated under conditions representative of practical use.
However, Vantocil IB is recommended that field tests under practical conditions be undertaken to determine the most cost-effective dose for your application.


Vantocil IB is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.


Vantocil IB can also be used to preserve aqueous-based adhesives (such as animal glues, latex adhesives based on polyvinyl acetate, PVA, starch, dextrin, casein and other glues, and latex adhesives intended for food packaging applications).
Recommended usage level of Vantocil IB is 500-5000 ppm.
Applications of Vantocil IB are varied, and include surface care, fabric care, and automotive care.


-Disinfection & Sanitization uses of Vantocil IB: 
Industrial, institutional, and domestic surface disinfection (e.g., hospitals, clinics, veterinary settings).
Food & beverage facilities for sanitation of food contact surfaces and processing equipment.
Agricultural settings including dairies, milking parlors, breweries, and egg hatcheries.
Water treatment and control of microbial contamination in systems like air-conditioning units.


-Formulation Additive uses of Vantocil IB:
Vantocil IB is used in cleaning products, surface care formulations, fabric care products and specialty industrial cleaners.
Vantocil IB is effective as a preservative in formulations such as adhesives, PVA and silicone emulsions, and various polymer systems.

FUNCTIONS of VANTOCIL IB:
*Anti-Microbial Agent, 
*Dispersant

FEATURES of VANTOCIL IB:
Vantocil IB is based on Arch's highly active biocide poly(hexamethylene biguanide) hydrochloride, also known as PHMB, which provides the following properties of direct relevance for controlling infections in livestock:
*Fast acting bactericide, effective at low concentrations
*Extensive toxicity studies suggest acceptable use
*Retains activity in the presence of organic matter such as
*Active against enveloped RNA, enveloped DNA, naked
*Readily dilutable in hot and cold water
*Provides stable formulations with both acids and alkalis
*Low corrosion, and compatible with common materials of
*Active in both soft and hard water
*Effective and stable over a pH range of 1 - 11
against Gram positive and Gram negative vegetative bacteria.
*At higher concentrations effective against yeasts risk to humans proteins and fats, so providing reliable performance in the presence of organic residues such as chicken faeces and blood DNA and naked RNA viruses construction at typical use levels.

CHARACTERISTICS & BENEFITS of VANTOCIL IB:
Vantocil IB offers a range of practical characteristics:

*Broad Antimicrobial Activity: 
Effective against a wide range of bacteria and microorganisms across many environments.

*Fast Acting: 
Rapid bactericidal action at relatively low usage concentrations.

*pH and Temperature Tolerance: 
Vantocil IB is stable and active in diverse pH ranges and temperatures.

*Compatibility: 
Vantocil IB provides good compatibility with many formulation systems including acidic, alkaline, and hard water conditions.

*Low Foam: 
Vantocil IB is suitable for cleaning systems where minimal foaming is desirable (e.g., CIP systems).

*Formulation Stability: 
Good thermal and chemical stability improves shelf life and efficacy across products.

KEY PROPERTIES of VANTOCIL IB:
Product: VANTOCIL IB (20 % PHMB solution)
Active Ingredient: poly(hexamethylene biguanide) hydrochloride (PHMB)
Physical Form: Liquid, pale yellow, aqueous solution
EC Number: 923-111-4
CAS Numbers: 27083-27-8; 32289-58-0; 133029-32-0 (for PHMB variants)
Major Applications of Vantocil IB: Industrial and institutional disinfectants, sanitizers, formulation preservative, surface care agents, agricultural hygiene systems.

PHYSICAL and CHEMICAL PROPERTIES of VANTOCIL IB:
Physical Form: Liquid, clear to pale yellow solution
Active Agent Content: ~20 % PHMB in water
pH: Typically in the range of 4.0–4.5 at 25 °C
Odor: Low, characteristic
Density: ~1.04 g/cm³ at 25 °C
Boiling Point: Approximately 102 °C
Viscosity: Around 5 mPa·s at 25 °C
Solubility: The solution is miscible with water, and PHMB itself dissolves readily in water
Product Name: VANTOCIL IB
Active Ingredient: poly(hexamethylene biguanide) hydrochloride (PHMB)
CAS Numbers: 27083-27-8, 32289-58-0, 133029-32-0

EC / EINECS Number: 923-111-4
INCI Name: Poly(hexamethylene biguanide) hydrochloride
Chemical Family: Biguanides
Substance / Product: VANTOCIL IB
Active substance: Poly(hexamethylene biguanide) hydrochloride (PHMB)
CAS Number: 27083-27-8
EC Number: 923-111-4
Molecular Formula: Not fixed
Molecular Weight: Not fixed / variable (Typical number-average molecular weight is often reported in the range of ~2,000–5,000 g/mol, depending on polymer chain length, but it is not a single exact value)

FIRST AID MEASURES of VANTOCIL IB:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of VANTOCIL IB:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of VANTOCIL IB:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of VANTOCIL IB:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of VANTOCIL IB:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of VANTOCIL IB:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available


 

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