PRODUCTS

VITAMIN A ACETATE

Vitamin A Acetate is a naturally-occurring fatty acid ester form of retinol (vitamin A) with potential antineoplastic and chemopreventive activities.
Vitamin A Acetate binds to and activates retinoid receptors, inducing cell differentiation and decreasing cell proliferation.
Vitamin A Acetate also inhibits carcinogen-induced neoplastic transformation in some cancer cell types and exhibits immunomodulatory properties.

CAS: 127-47-9
European Community (EC) Number: 204-844-2

Molecular Formula: C22H32O2
Molecular Weight: 328.5 g/mol

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response.
Dietary vitamin A is derived from a variety of carotenoids found in plants.
Vitamin A is enriched in the liver, egg yolks, and the fat component of dairy products.

Vitamin A Acetate, a variant of vitamin A, holds multifaceted applications in the realms of medicine, science, and industry.
Vitamin A Acetate's characteristics include being a colorless, slightly viscous liquid with solubility in most organic solvents.
Naturally occurring, Vitamin A Acetate serves as a precursor to the biologically active form of vitamin A known as retinoic acid.
Vitamin A Acetate's primary uses revolve around dietary supplementation and its longstanding presence in the cosmetics industry.
The precise mechanism of action behind retinyl acetate remains incompletely understood.
However, Vitamin A Acetate is believed to scavenge free radicals.
Furthermore, Vitamin A Acetate is thought to exert influence over gene expression and affect the activity of specific enzymes and proteins.

Retinyl acetate (retinol acetate, vitamin A acetate) is a natural form of vitamin A which is the acetate ester of retinol.
Vitamin A Acetate has potential antineoplastic and chemopreventive activities.

In the United States, Vitamin A Acetate is classified generally recognized as safe (GRAS) in the amounts used to fortify foods with vitamin A.

Also called "The Normaliser", Vitamin A Acetate (Retinol) has attracted great interest in recent years as it is the active agent for treatment of aging skin in beauty care.
Vitamin A promotes the enzyme activity in the skin.
Vitamin A Acetate thickens the epidermis and can regenerate skin prematurely aged by UV-radiation.
Vitamin A Acetate can also assist in increasing the skin's elasticity and the reversal of photodamage.
Vitamin A is widely used in products such as moisturisers, lotions, body butters, shampoos, conditioners, gels and scrubs.
Vitamin A Acetate is particularly good for anti-aging formulations.
Vitamin A is for cosmetic use only.

Vitamin A Acetate promotes collagen synthesis and can reduce the appearance of fine lines and wrinkles.
Additionally, Vitamin A Acetate helps keep pores clear and remove the oil that can lead to blemishes.
Add Vitamin A Acetate to your skincare routine with this ingredient.
Use Vitamin A Acetate to include in your everyday skin cream or any oil-based product to help with oil and blemish control.
This add-on can help you DIY a unique formulation that will enhance your daily routine.

Vitamin A Acetate is recommended for use at up to 1% in formulations.
Vitamin A Acetate is soluble in organic solvents, fats, and mineral oils but is water dispersable.
Stabilize this ingredient with vitamin E (Tocopherol (Vitamin E)) and store the formula in a container which shields it from light.
Vitamin A Acetate is unstable in the presence of acids.

Vitamin A Acetate is a gentler form of vitamin A than retonic acid, found in prescription products.
Store Vitamin A Acetate in a cool dark place for best results.

Vitamin A Acetate is also known as retinyl acetate or retinol acetate and is often used to fortify foods with vitamin A.

Vitamin A Acetate (Retinyl, Retinol) is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.

APPLICATIONS:

Vitamin A Acetate is one of our most popular sources of vitamin A.
Vitamin A Acetate is permitted in the following categories of foods:

• Food supplements (as per Directive 2002/46/EC)

• Fortified foods (as per Regulation 1925/2006)

• Infant formulae and follow on formulae (as per Directive 2006/141/EC)

• Processed cereal-based foods and baby foods for infants and young children (as per Directive 2006/125/EC, Regulation 609/2013)

• Foods for Special Medical Purposes & Total Diet Replacements for Weight Control (as per Regulation 609/2013)

Vitamin A Acetate is made by carrying retinol acetate on carriers and stabilisers (vegetable oils, gum arabic, sucrose, maltodextrin) with a small amount of antioxidant (vitamin E) and anti-caking agent (silicon dioxide) added so that the preparation is cold water soluble.
The preparation is vegetarian and vegan suitable.

Dose

Care should be taken when dosing fat-soluble vitamins and they are less readily excreted as the water-soluble vitamins.

The upper limit for vitamin A (adults) is 3000µmg/day.
The upper limit applies to vitamin A as retinol or retinyl esters.

Vitamin A acetate (also known as retinyl acetate) is a fatty acid ester form of vitamin A with antineoplastic and chemopreventive effect.
Vitamin A Acetate activated retinoid receptor to induce cell differentiation and decrease cell proliferation.
It also exhibited immunomodulatory properties and blocks carcinogen-induced neoplastic transformation.

Retinoid receptors mediate retinoids activities and involved in normal growth and development maintenance, immune response and reproduction.

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A.
The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.
Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Vitamin A Acetate, a variant of vitamin A, holds multifaceted applications in the realms of medicine, science, and industry.
Vitamin A Acetate's characteristics include being a colorless, slightly viscous liquid with solubility in most organic solvents.
Naturally occurring, Vitamin A Acetate serves as a precursor to the biologically active form of vitamin A known as retinoic acid.
Vitamin A Acetate's primary uses revolve around dietary supplementation and its longstanding presence in the cosmetics industry.
The precise mechanism of action behind Vitamin A Acetate remains incompletely understood.
However, Vitamin A Acetate is believed to scavenge free radicals.
Furthermore, Vitamin A Acetate is thought to exert influence over gene expression and affect the activity of specific enzymes and proteins.

Vitamin A (also called retinol) is important for cell growth, immune function, vision and skin and mucosal health.
Although vitamin A does not contribute directly to burning fat, its contribution to overall health makes it so essential that a deficiency would be detrimental during a diet.
First and foremost, there would be a lack of appetite and a tendency to pick up infections - both symptoms that negatively influence the metabolism when vitamin A is missing.
-Supports cell growth
-Strengthens the immune system
-Supports eyesight
-Supports skin and mucosal health

Vitamin A Acetate improves the firmness and resilience of the skin.
Vitamin A Acetate has an anti-wrinkling effect and helps to regenerate UV- damaged skin.
Skin thickness increases significantly, caused by an increase in collagen and procollagen production.
Vitamin A Acetate also increases skin cell growth to heal lesions and scars.
Vitamin A Acetate is also used in anti-acne products for decreasing inflammation of the skin and decreases the sebum production.

Suitable for anti-wrinkle products, day and night creams, anti-acne and sun care products.

Cosmetic benefits

-synthetic production process to obtain Vitamin A Acetate
-in human body vitamin A acetate is transformed to Vitamin A
-content of Vitamin A >= 2 800 000 I.U./g
-use in anti-acne products for decreasing inflammation of the skin
-decreases sebum production
-increases skin cell growth to heal lesions and scars
-helps to regenerate UV damaged skin

SYNONYMS:

RETINYL ACETATE
Vitamin A acetate
Retinol acetate
127-47-9
Retinol, acetate
all-trans-Retinyl acetate
Crystalets
Vitamin A1 acetate
all-trans-Retinol acetate
Vitamin A alcohol acetate
Davitan A 650
Vitamin A ester
all-trans-Vitamin A acetate
Retinol, acetate, all-trans-
O~15~-acetylretinol
NSC 122045
trans-Retinyl acetate
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
RO 1-5275
Retinol acetate [JAN]
trans-Vitamin A acetate
[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
Myvak (VAN)
Myvax (VAN)
3LE3D9D6OY
all-trans-Retinylacetate
DTXSID6021240
CHEBI:32095
Vitamin A acetate (VAN)
Acetic acid, retinyl ester
9-cis,13-cis-Retinol15-Acetate
NSC-122045
NSC-122760
NCGC00090756-09
Retinol Acetate/All-trans-retinyl Acetate
VitaminAacetate
Vitamin A acetate (tritiated)
DTXCID701240
Vitamin A, acetate
Retinol, acetate, labeled with tritium
O(15)-acetylretinol
9-cis Retinol Acetate
Retinyl acetate, all-trans-
CAS-127-47-9
CCRIS 1907
trans-Retinol Acetate
SR-05000001431
EINECS 204-844-2
UNII-3LE3D9D6OY
BRN 1915439
Retinol acetate;Vitamin A acetate
retinyl-acetate
WLN: L6UTJ A1 B1U1Y1 & U2U1Y1 & U2OV1 C1 C1
Vitamin A acetat
29444-27-7
MFCD00019413
ORISTAR RA
9-cis-Retinol acetate;9-cis-Vitamin A acetate
Spectrum5_001195
Spectrum5_002001
Retinol acetate (JP17)
Retinyl (Retinol) Acetate
EC 204-844-2
retinol, O~15~-acetyl-
BSPBio_002833
SPECTRUM1503051
RETINYL ACETATE [INCI]
C22H32O2 (retinol acetate)
CHEMBL486193
VITAMIN A ACETATE [MI]
CHEBI:94695
HMS501K04
RETINOL ACETATE [WHO-DD]
RETINYL ACETATE [USP-RS]
VITAMIN A ACETATE [VANDF]
HMS1922A19
HMS2089G20
Pharmakon1600-01503051
AMY13865
HY-N0679
Retinyl acetate, analytical standard
Tox21_113549
Tox21_201423
Tox21_302737
BDBM50442911
CCG-39564
LMPR01090012
NSC122045
NSC122760
NSC758220
s4083
AKOS015914999
Tox21_113549_1
CS-8187
NSC-758220
3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
IDI1_000522
NCGC00090756-01
NCGC00090756-02
NCGC00090756-03
NCGC00090756-05
NCGC00090756-06
NCGC00090756-07
NCGC00090756-08
NCGC00090756-10
NCGC00090756-11
NCGC00090756-12
NCGC00256509-01
NCGC00258974-01
VITAMIN A (AS ACETATE) [VANDF]
64536-04-5
AC-19999
ALL-(E)-RETINOL ACETATE [WHO-IP]
SBI-0051756.P002
VITAMIN A ACETATE 1.5 M.I.U./G
RO-1-5275
A16783
D01621
H12041
Vitamin A acetate 10 microg/mL in Acetonitrile
AB00052305-02
AB00052305_03
EN300-18533003
EN300-25359996
Vitamin A acetate in gelatin, 500,000 I.U./g
Q7316808
SR-05000001431-1
SR-05000001431-3
W-108382
BRD-K65331431-001-01-3
Vitamin A (acetate), meets USP testing specifications
VITAMIN A (AS ACETATE & BETA CAROTENE) [VANDF]
Retinol acetate, European Pharmacopoeia (EP) Reference Standard
Retinyl acetate, synthetic, crystalline solid or supercooled liquid
Retinyl acetate, United States Pharmacopeia (USP) Reference Standard
Retinyl acetate, solid or viscous liquid, BioReagent, synthetic, suitable for cell culture
Retinyl acetate, synthetic, matrix dispersion, 475,000-650,000 USP units/g
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenyl acetate
3,7-Dimethyl-9-(2,6,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol acetate, (all trans)-
InChI=1/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14
Retinyl Acetate (Vitamin A Acetate), Pharmaceutical Secondary Standard; Certified Reference Material