PRODUCTS

VITAMIN B6

Vitamin B6 is a water-soluble member of the B-complex vitamin family that plays an indispensable role in human metabolism and overall health.
Vitamin B6, principally in its biologically active coenzyme form pyridoxal-5′-phosphate (PLP), is involved in more than one hundred enzymatic reactions, including amino acid metabolism, neurotransmitter synthesis, glycogen breakdown, hemoglobin production, and modulation of steroid hormone action.
Vitamin B6’s biochemical versatility and necessity for vital metabolic pathways make it one of the cornerstone vitamins for maintaining physiological balance, neurological health, and overall well-being.

CAS Number: 65-23-6
EC Number: 200-603-0
Molecular Formula: C₈H₁₁NO₃
Molecular Weight: 169.18 g/mol

Synonyms: pyridoxine, vitamin B6, Pyridoxol, Gravidox, Pyridoxin, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, Hydoxin, Adermine, Pyridoxolum, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, Pyridoxinum, Piridossina , 3-Hydroxy-4,5-dimethylol-alpha-picoline, Pyridoxinum , Piridossina, Pyridoxine , Aderoxine, 2-Picoline-4,5-dimethanol, 3-hydroxy-, (5-Hydroxy-6-methylpyridine-3,4-diyl)dimethanol, 2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine, Hexa-Betalin, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, 2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine, Pyridoxin hydrochloride, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, Pyridoxine free base, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German], 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol, 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, Adermin hydrochloride, Pyridoxinum hydrochloricum, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin, Pyridoxine hydrogen chloride, 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine, Adermin, Bezatin, Pirivitol, Infuvite Pediatric, Pyridoxine (Vit B6), M.V.I.-12 Lyophilized, Pridoxine, VitaminB6, Pyridoxine, Beesix , nchembio.93-comp1, Becilan , Benadon , Hexobion , Vitamin B6 , Pyridoxol, Vitamin B6, Pyridoxol; Vitamin B6, Hexabetalin , Vitamin b6,hydrochloride, Pyridoxol, Vitamin B6, Gravidox, Pharmakon1600-01505453, 3-hydroxy-2-Picoline-4,5-dimethanol, Vitamin B6 100 microg/mL in Methanol, 3-Hydroxy-4,5-dimethylol-.alpha.-picoline, 4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol, 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol #, 2-Methyl-3-oxylato-4,5-bis(hydroxymethyl)pyridinium, 2-methyl-3-hydroxy-4-hydroxymethyl-5-hydroxymethyl pyridine

Vitamin B6 is a water-soluble vitamin that plays a vital role in amino acid, glucose, and lipid metabolism.
Vitamin B6 typically occurs as a white, crystalline powder with a slightly bitter taste and is stable under normal conditions but sensitive to light and heat.

Functionally, Vitamin B6 serves as a precursor to the active coenzyme form, pyridoxal-5′-phosphate (PLP), which participates in numerous enzymatic reactions, including neurotransmitter synthesis (serotonin, dopamine, GABA), hemoglobin production, and the conversion of tryptophan to niacin.
Vitamin B6 is widely found in foods such as poultry, fish, bananas, fortified cereals, and legumes.

Due to its essential role in nervous system function and red blood cell formation, Vitamin B6 deficiency can result in symptoms such as irritability, confusion, anemia, and peripheral neuropathy, while excessive supplementation may cause sensory nerve damage.
Vitamin B6's broad metabolic importance makes Vitamin B6 a critical nutrient for overall health and biochemical balance.

Vitamin B6 plays an important role in the body.
Vitamin B6 is needed to maintain the health of nerves, skin, and red blood cells.

Vitamin B6 has been used to prevent or treat a certain nerve disorder (peripheral neuropathy) caused by certain medications (such as isoniazid).
Vitamin B6 has also been used to treat certain hereditary disorders (such as xanthurenic aciduria, hyperoxaluria, homocystinuria).

Vitamin B6 plays an important role in the body.
Vitamin B6 is needed to maintain the health of nerves, skin, and red blood cells.

Vitamin B6 is required by your body for utilization of energy in the foods you eat, production of red blood cells, and proper functioning of nerves.
As a supplement Vitamin B6 is used to treat and prevent Vitamin B6 deficiency, sideroblastic anaemia, Vitamin B6-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.

Vitamin B6 is used by mouth or by injection.
Vitamin B6 is usually well tolerated.

Vitamin B6 is a water-soluble vitamin that your body needs for several functions.
Vitamin B6’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.

Vitamin B6 is a water-soluble member of the B-complex vitamin family that plays an indispensable role in human metabolism and overall health.
Chemically, Vitamin B6 belongs to a group of related compounds including pyridoxal and pyridoxamine, all of which can be converted in the body into the active coenzyme form, pyridoxal-5′-phosphate (PLP).

Vitamin B6 is essential for more than one hundred enzymatic reactions, particularly those involved in amino acid metabolism, neurotransmitter synthesis, glycogen breakdown, hemoglobin production, and modulation of steroid hormone action.
For example, PLP is required for the synthesis of key neurotransmitters such as serotonin, dopamine, norepinephrine, and gamma-aminobutyric acid (GABA), which are critical for mood regulation, cognition, and normal nervous system function.
Vitamin B6 also supports the conversion of tryptophan into niacin, linking Vitamin B6 to the maintenance of healthy skin, energy metabolism, and proper functioning of the immune system.

From a nutritional standpoint, Vitamin B6 is widely distributed in both plant and animal foods, with rich sources including poultry, fish, organ meats, fortified cereals, bananas, nuts, seeds, and legumes.
Because Vitamin B6 is water-soluble, the vitamin is not stored extensively in the body, making regular dietary intake important to prevent deficiency.

Insufficient levels of Vitamin B6 can manifest as irritability, depression, confusion, impaired immune response, glossitis, microcytic anemia, and peripheral neuropathy, particularly when combined with deficiencies of other B vitamins.
On the other hand, excessive intake, usually from long-term supplementation at high doses, can lead to neurotoxicity characterized by sensory nerve damage, numbness, and tingling in the extremities.

Clinically, Vitamin B6 supplementation has been studied for its potential benefits in conditions such as premenstrual syndrome (PMS), morning sickness during pregnancy, carpal tunnel syndrome, homocysteine regulation in cardiovascular disease, and certain types of epilepsy.
While research is ongoing, Vitamin B6's established role in neurotransmitter synthesis and hemoglobin metabolism underscores its therapeutic importance.
In industry, Vitamin B6 is widely used to fortify foods and dietary supplements, helping to ensure adequate intake in populations with limited dietary diversity.

Physically, Vitamin B6 appears as a white crystalline powder with a mildly bitter taste, soluble in water, and stable under normal storage conditions though sensitive to prolonged exposure to light and heat.
Vitamin B6's biochemical versatility and necessity for vital metabolic pathways make it one of the cornerstone vitamins for maintaining physiological balance, neurological health, and overall well-being.

Vitamin B6 is a monohydroxypyridine, a member of methylpyridines and a hydroxymethylpyridine.
Vitamin B6 an important water-soluble vitamin that is naturally present in many foods.

As Vitamin B6's classification as a vitamin implies are essential nutrients required for normal functioning of many biological systems within the body.
While many plants and microorganisms are able to synthesize Vitamin B6 through endogenous biological processes, animals must obtain it through their diet.

More specifically, Vitamin B6 is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid.
Vitamin B6 is collective term for a group of three related compounds, Vitamin B6, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, Vitamin B6 5'-phosphate, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate.

Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).
Vitamin B6 is also used in combination with for the treatment of nausea and vomiting in pregnancy.

Vitamin B6 is a hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2.
The 4-methanol form of Vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.

Vitamin B6 has a role as:
A cofactor,
A human metabolite,
A Saccharomyces cerevisiae metabolite,
An Escherichia coli metabolite
A mouse metabolite

Market Overview of Vitamin B6:
The global Vitamin B6 market is on a steady growth trajectory, fueled by rising consumer awareness of preventive health, the widespread adoption of dietary supplements, and the increasing use of Vitamin B6 in fortified foods, pharmaceuticals, and animal feed.
Market size estimates vary across reports, ranging from about US $90 million to over US $700 million, with projected compound annual growth rates (CAGR) between 4.5% and 9% over the next decade.

North America currently represents the largest market share due to high supplement consumption, while the Asia-Pacific region, particularly China, is emerging as the fastest-growing hub thanks to urbanization, dietary shifts, and strong manufacturing capacity.
Tablets remain the most dominant product form, followed by capsules, syrups, and injectable preparations, with online distribution channels gaining significant momentum alongside traditional pharmacies.

Recent trends indicate moderate global production growth led by Chinese manufacturers, coupled with some price volatility—such as a recent 5.7% decline in North American spot prices.
The competitive landscape is shaped by leading global players like DSM, Lonza, BASF, and Merck, which continue to invest in capacity expansion, new product launches, and strategic partnerships.
Overall, the Vitamin B6 market reflects a balance of consistent demand from health-conscious consumers and evolving applications across multiple industries, ensuring its continued expansion in the years ahead.

Uses of Vitamin B6:
Vitamin B6 is important for many processes in the body.
Vitamin B6 is also used to treat a certain type of anemia (lack of red blood cells).
Vitamin B6 injection is also used to treat some types of seizure in babies.

Vitamin B6 taken by mouth (oral) is available without a prescription.
Injectable Vitamin B6 must be given by a healthcare professional.

Vitamin B6 is required by your body for utilization of energy in the foods you eat, production of red blood cells, and proper functioning of nerves.
Vitamin B6 found commonly in food and used as a dietary supplement.
As a supplement Vitamin B6 is used to treat and prevent Vitamin B6 deficiency, sideroblastic anaemia, Vitamin B6-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.

Vitamin B6 is used by mouth or by injection.
Vitamin B6 is usually well tolerated.

Vitamin B6 is in the vitamin B family of vitamins.
Vitamin B6 is required by the body to metabolise amino acids, carbohydrates, and lipids.
Sources in the diet include fruit, vegetables, and grain

Vitamin B6 is a vitamin used for preventing and treating low levels of Vitamin B6 (Vitamin B6 deficiency) and the "tired blood" (anemia) that may result.
Vitamin B6 is also used for heart disease; high cholesterol; reducing blood levels of homocysteine.

Vitamin B6, or Vitamin B6, is a water-soluble vitamin found naturally in many foods, as well as added to foods and supplements.
Vitamin B6 is the active coenzyme form and most common measure of B6 blood levels in the body.

Vitamin B6 is a coenzyme that assists more than 100 enzymes to perform various functions, including the breakdown of proteins, carbohydrates, and fats; maintaining normal levels of homocysteine (since high levels can cause heart problems);
Vitamin B6 is supporting immune function and brain health.

Food Sources:
Vitamin B6 is found in a variety of animal and plant foods.
Beef liver
Tuna
Salmon
Fortified cereals
Chickpeas
Poultry
Some vegetables and fruits, especially dark leafy greens, bananas, papayas, oranges, and cantaloupe

Medical Uses:
As a treatment (oral or injection), Vitamin B6 is used to treat or prevent Vitamin B6 deficiency, sideroblastic anaemia, Vitamin B6-dependent epilepsy, certain metabolic disorders, side effects of isoniazid treatment and certain types of mushroom poisoning.
Isoniazid is an antibiotic used for the treatment of tuberculosis.

Co-treatment with Vitamin B6 alleviates the numbness.
Vitamin B6-dependent epilepsy is a type of rare infant epilepsy that does not improve with typical anti-seizure medications.
Vitamin B6 in combination with doxylamine is used as a treatment for morning sickness in pregnant women.

Mechanism of it:
Vitamin B6 is in the vitamin B family of vitamins.
Vitamin B6 is required by the body to make amino acids, carbohydrates, and lipids.

Sources in the diet include fruit, vegetables, and grain.
Vitamin B6 is also required for muscle phosphorylase activity associated with glycogen metabolism.

Your body cannot produce Vitamin B6, so you must obtain it from foods or supplements.
Most people get enough Vitamin B6 through their diet, but certain populations may be at risk for deficiency.
Consuming adequate amounts of Vitamin B6 is important for optimal health and may even prevent and treat chronic diseases

Human Nutrition & Health:
Vitamin B6 acts as an essential coenzyme (pyridoxal-5′-phosphate) for over 100 enzymatic reactions.
Vitamin B6 supports amino acid metabolism, neurotransmitter synthesis (serotonin, dopamine, GABA), and hemoglobin production.

Vitamin B6 helps regulate homocysteine levels, reducing cardiovascular risk.
Vitamin B6 is used in the management of premenstrual syndrome (PMS), morning sickness during pregnancy, carpal tunnel syndrome, and certain seizure disorders.

Pharmaceutical Industry:
Vitamin B6 is formulated in tablets, capsules, syrups, and injections for therapeutic use.
Vitamin B6 is incorporated into multivitamin complexes and B-complex formulations.

Vitamin B6 is utilized as an adjunct therapy in isoniazid (tuberculosis drug) treatment to prevent neuropathy.
Vitamin B6 is applied in certain metabolic or genetic disorders where B6-dependent enzymes are impaired.

Food & Beverage Industry:
Vitamin B6 is widely used in fortified foods and beverages such as cereals, nutrition bars, dairy products, and energy drinks.
Vitamin B6 is added to dietary supplements for athletes and health-conscious consumers.
Vitamin B6 plays a role in functional foods, promoting energy metabolism and immune support.

Animal Nutrition:
Vitamin B6 is incorporated into livestock and poultry feed to support growth, reproduction, and nervous system function.
Vitamin B6 prevents deficiency symptoms in animals, such as growth retardation, convulsions, or anemia.

Cosmetic & Personal Care:
Vitamin B6 is occasionally included in skin and hair care formulations for its role in protein metabolism and potential to support healthy skin.

Benefits of Vitamin B6:
Vitamin B6 Improves Mood and Reduce Symptoms of Depression.
Vitamin B6 Promotes Brain Health and Reduce Alzheimer’s Risk.

Vitamin B6 Prevents and Treat Anemia by Aiding Hemoglobin Production.
Vitamin B6 is Useful in Treating Symptoms of PMS.

Vitamin B6 Helps Treat Nausea During Pregnancy.
Vitamin B6 Prevents Clogged Arteries and Reduce Heart Disease Risk.

Vitamin B6 Helps Prevent Cancer.
Vitamin B6 Promotes Eye Health and Prevent Eye Diseases.
Vitamin B6 Treats Inflammation Associated With Rheumatoid Arthritis.

Production of Vitamin B6:

Chemical Synthesis:
Manufacturers typically produce Vitamin B6 hydrochloride (the most common commercial form) through multi-step chemical synthesis.
Manufacturers generally start with petrochemical intermediates such as 2-methyl-3-hydroxypyridine or similar pyridine derivatives.

Manufacturers employ catalytic reactions, oxidation, and substitution steps to form the Vitamin B6 structure.
Manufacturers finally neutralize the compound with hydrochloric acid to obtain Vitamin B6 hydrochloride, which is stable and suitable for pharmaceutical and food applications.

Biotechnological Methods:
Researchers have developed microbial fermentation processes to produce Vitamin B6 using genetically engineered microorganisms such as Escherichia coli or Bacillus subtilis.
Researchers optimize metabolic pathways in microbes to increase yield of Vitamin B6 from simple substrates like glucose or glycerol.
Researchers consider these methods more sustainable and eco-friendly compared to purely chemical synthesis, although large-scale industrial adoption remains limited.

Industrial Production & Capacity:
Global manufacturers such as DSM, BASF, Lonza, and several Chinese producers dominate the Vitamin B6 supply.
China accounts for the largest share of global production, supplying pharmaceutical, food, and feed industries worldwide.

Global production volumes have shown modest growth, with estimates indicating an increase from about 7,000 metric tons in 2012 to nearly 8,000 metric tons in 2018.
Market analysts expect production to expand steadily in response to growing demand in supplements, fortified foods, and animal nutrition.

Quality Control & Purification:
Manufacturers ensure purity through crystallization, filtration, and drying processes.
Manufacturers analyze the final product for compliance with pharmacopeial standards such as USP, EP, or JP.
Manufacturers package Vitamin B6 hydrochloride in moisture-resistant containers to preserve stability and potency.

Synthesis of Vitamin B6:

Classical Chemical Synthesis:
Chemists typically synthesize Vitamin B6 through multi-step reactions starting from 2-methyl-3-hydroxypyridine or other substituted pyridines.
Chemists introduce hydroxymethyl groups at the 4- and 5-positions of the pyridine ring using controlled formylation and reduction reactions.

Chemists often use oxidation, substitution, and rearrangement steps to complete the assembly of the Vitamin B6 framework.
Chemists finally convert the free base into Vitamin B6 hydrochloride by neutralization with hydrochloric acid, which produces the stable, crystalline form used commercially.

Alternative Routes:
Researchers have explored condensation of acetaldehyde derivatives with hydroxypyridine precursors as alternative synthetic routes.
Researchers sometimes employ Grignard reactions or catalytic hydrogenation to achieve specific substitutions on the pyridine ring.
Researchers adapt these routes depending on raw material availability, cost, and environmental considerations.

Biotechnological Synthesis:
Scientists have engineered microorganisms such as Escherichia coli and Bacillus subtilis to produce Vitamin B6 through fermentation-based processes.
Scientists modify microbial metabolic pathways (e.g., deoxyxylulose phosphate pathway) to increase flux toward Vitamin B6 biosynthesis.
Scientists consider fermentation methods more sustainable, offering lower environmental impact compared to traditional petrochemical synthesis.

Industrial Considerations:
Manufacturers choose chemical synthesis for high-volume, cost-effective production, especially in China where large-scale facilities dominate supply.
Manufacturers increasingly investigate green chemistry methods and microbial fermentation to align with sustainability goals and regulatory pressure.
Manufacturers prioritize yield optimization, purification efficiency, and product stability during process scale-up.

History of Vitamin B6:

Discovery:
Scientist Paul György first identified Vitamin B6 in 1934 while studying a nutritional factor that prevented dermatitis in rats.
Scientist Paul György named the compound Vitamin B6 to distinguish it from other members of the B-complex family.
Scientist Paul György recognized that Vitamin B6 was essential for amino acid metabolism and normal growth.

Isolation and Characterization:
Chemists successfully isolated pure Vitamin B6 in 1938, providing the first crystalline samples of the vitamin.
Chemists determined the chemical structure as 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, confirming its pyridine-based backbone.
Chemists demonstrated that Vitamin B6 could be converted in the body into its active coenzyme form, pyridoxal-5′-phosphate (PLP).

Early Synthetic Pathways:
Organic chemists developed the first laboratory synthesis of Vitamin B6 in the late 1930s, enabling broader availability for research.
Organic chemists refined synthetic routes during the 1940s, leading to the production of Vitamin B6 hydrochloride as a stable and easily distributed form.
Organic chemists laid the foundation for industrial-scale production by establishing efficient multi-step chemical pathways.

Industrial and Medical Adoption:
Pharmaceutical companies began producing Vitamin B6 commercially during the 1940s to support nutrition programs and deficiency prevention.
Governments incorporated Vitamin B6 into fortified foods and B-complex supplements to address widespread deficiencies during and after World War II.
Physicians recognized Vitamin B6’s therapeutic importance in preventing neuropathy, anemia, and metabolic disorders.

Modern Developments:
Researchers expanded the role of Vitamin B6 in the late 20th century by linking it to neurotransmitter synthesis, immune regulation, and cardiovascular health.
Manufacturers scaled up production globally, with China emerging as the dominant supplier in the late 20th and early 21st centuries.
Scientists continue to explore new biotechnological methods for Vitamin B6 synthesis, emphasizing sustainability and reduced environmental impact.

Handling and Storage of Vitamin B6:

Handling:
Handle Vitamin B6 with care and avoid contact with skin, eyes, and clothing.
Do not breathe dust, vapors, or mists.

Handle Vitamin B6 only in well-ventilated areas or under local exhaust ventilation.
Wear appropriate protective equipment such as gloves, goggles, and a lab coat.
Wash hands thoroughly with soap and water after handling Vitamin B6.

Storage:
Store Vitamin B6 in tightly closed containers in a cool, dry, and well-ventilated place.
Protect Vitamin B6 from heat, direct sunlight, and sources of ignition.
Keep Vitamin B6 away from strong oxidizers and strong acids.

Stability and Reactivity of Vitamin B6:

Stability:
Vitamin B6 is stable under normal temperature and pressure conditions.

Reactivity:
Vitamin B6 may react with strong oxidizing agents, strong acids, and alkali metals.
Thermal decomposition or combustion of Vitamin B6 can produce carbon monoxide, carbon dioxide, and phenolic vapors.

First Aid Measures of Vitamin B6:

Inhalation:
Move the affected person to fresh air if Vitamin B6 dust is inhaled.
Provide oxygen if breathing is difficult.
Seek medical attention if symptoms persist.

Skin Contact:
Wash affected skin immediately with soap and plenty of water.
Remove contaminated clothing.
Obtain medical advice if irritation develops.

Eye Contact:
Rinse eyes cautiously with plenty of water for at least 15 minutes, lifting eyelids occasionally.
Remove contact lenses if present.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth thoroughly with water if Vitamin B6 is ingested.
Do not induce vomiting.
Give plenty of water to drink and seek immediate medical attention.

Firefighting Measures of Vitamin B6:

Extinguishing Media:
Use carbon dioxide, foam, dry chemical powder, or water spray to extinguish fires involving Vitamin B6.

Hazards:
Burning Vitamin B6 may release toxic fumes such as carbon monoxide and carbon dioxide.

Protective Equipment:
Firefighters should wear self-contained breathing apparatus (SCBA) and full protective clothing when fighting fires involving Vitamin B6.

Accidental Release Measures of Vitamin B6:

Personal Precautions:
Wear protective gloves, goggles, and suitable protective clothing during spill response.
Ensure adequate ventilation and avoid inhalation of vapors or dust.

Spill Cleanup:
Absorb spilled Vitamin B6 with inert material such as sand, diatomaceous earth, or vermiculite.
Place the absorbed material into a suitable container for disposal.

Wash the affected spill area thoroughly with water after cleanup.
Prevent Vitamin B6 from entering drains, surface water, or soil.

Exposure Controls / Personal Protection of Vitamin B6:

Engineering Controls:
Provide adequate local exhaust ventilation or general ventilation to maintain airborne levels of Vitamin B6 as low as possible.

Personal Protection:

Respiratory:
Use an approved respirator if exposure limits are exceeded.

Skin:
Wear chemical-resistant gloves such as nitrile or neoprene.

Eyes:
Use safety goggles or a face shield for eye protection.

Body:
Wear protective laboratory clothing such as a lab coat or chemical-resistant apron.

Hygiene Measures:
Do not eat, drink, or smoke while handling Vitamin B6.
Wash hands, face, and any exposed skin thoroughly after handling.

Identifiers of Vitamin B6:
CAS Number: 65-23-6
EC Number: 200-603-0
UNII: KV2JZ1BI6Z
PubChem CID: 1051
ChemSpider ID: 1020
IUPAC Name: 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
Molecular Formula: C₈H₁₁NO₃
Molecular Weight: 169.18 g/mol
InChI Key: LXNHXLLTXMVWPM-UHFFFAOYSA-N
SMILES: CC1=NC=C(C(=C1CO)CO)O
KEGG ID: C00314
ChEBI ID: 16709
DrugBank ID: DB00165
HSDB ID: 3496
ECHA InfoCard: 100.000.198

Properties of Vitamin B6:
Exact Mass: 169.07389321
Monoisotopic Mass: 169.07389321
Topological Polar Surface Area: 73.6 Å²
Physical Description: Solid
Melting Point: 159-162 °C
Solubility: 220000 mg/L
LogP: -0.77
Collision Cross Section: 134.6 Å²

Appearance: White or almost white crystalline powder
Odor: Practically odorless
Taste: Slightly bitter
Molar Mass: 169.18 g/mol
Molecular Formula: C₈H₁₁NO₃
Density: ~1.4 g/cm³
Melting Point: 159–162 °C
Boiling Point: 265 °C (decomposes)
Solubility in Water: 20 g/L at 25 °C
Solubility in Ethanol: Freely soluble
Partition Coefficient (logP): –0.71
pKa: 5.6 (hydroxyl group)
Vapor Pressure: Negligible at room temperature
Flash Point: 149.6 °C (closed cup)
Stability: Stable under normal conditions, light sensitive

Molecular Weight: 169.18
XLogP3: -0.8
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Heavy Atom Count: 12
Complexity: 142
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance: White crystalline powder
Odor: Practically odorless
Taste: Slightly bitter
Molecular Formula: C₈H₁₁NO₃
Molar Mass: 169.18 g/mol
Density: 1.4 g/cm³
Melting Point: 159–162 °C
Boiling Point: 265 °C (decomposition)
Refractive Index: 1.618
Water Solubility: 20 g/L at 25 °C
Ethanol Solubility: Freely soluble
Methanol Solubility: Freely soluble
Acetone Solubility: Slightly soluble
Partition Coefficient (logP): –0.71
pKa Values: 5.6; 8.9; 10.4
Vapor Pressure: <0.01 mmHg at 25 °C
Flash Point: 149.6 °C (closed cup)
Auto-Ignition Temperature: 510 °C
Heat of Combustion: –3,920 kJ/mol
Stability: Stable under normal storage; light sensitive
Crystal Structure: Monoclinic
Molar Volume: 121.2 cm³/mol
Surface Tension: 45.7 dyn/cm (aqueous solution, 20 °C)
Viscosity: 0.89 mPa·s (aqueous solution, 25 °C)