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WANOL F3156 is a proprietary polyether polyol used mainly as a raw material in polyurethane production, especially for making flexible and rigid foam systems.
WANOL F3156 is not a single simple molecule but a designed polymer blend with controlled molecular weight and reactivity.
WANOL F3156 makes it an industrial intermediate rather than a consumer chemical.
CAS Number: 9003-11-6
Molecular Formula: (C3H6O.C2H4O)x
Molecular Weight: 102.13
EINECS Number: 618-355-0
Synonyms: Nitrous oxide, Laughing gas, Dinitrogen oxide, Dinitrogen monoxide, Nitrogen oxide (N₂O), Nitrogen oxide (n₂o), Nitrogen protoxide, Protoxide of nitrogen, Nitrogen hypoxide, Hyponitrous acid anhydride, Factitious air, Gas, Laughing, Nitrous oxide compressed, Nitrous oxide refrigerated liquid, Nitrous Oxide USP, Nitrous oxide [JAN], Nitrous oxide [USP:JAN], Nitrous oxide (JP15/USP), Nitrous oxide (JP18/USP), Nitrous oxide (TN), Nitrous oxide [Anaesthetics, volatile], Nitrogenum oxygenatum, Dinitrogenii oxidum, Dinitrogenii oxidum [WHO-IP Latin], Lachgas, Distickstoffmonoxid, Stickstoff(I)-oxid, Stickdioxyd, Oxyde nitreux, Protoxyde d'azote, Gaz hilarant, Oxido nitroso, Nitroux Oxide, Nitrious oxide, Diazyne 1-oxide, Oxo-1λ⁵-diazyne, Oxidodinitrogen(N–N), N₂O, NNO, R-744A, CAS 10024-97-2, CAS 100240-04-8, EINECS 233-032-0, EC 233-032-0, UNII K50XQU1029, UN1070, UN2201, INS No. 942, INS-942, E-942, E942, FEMA No. 2779, FEMA 2779, CHEBI:17045, DTXSID8021066, DTXCID301066, RefChem:6663, HSDB 504, CHEMBL1234579, DB06690, Q905750, Nitrous oxide [UN1070] [Nonflammable gas], Nitrous oxide refrigerated liquid [UN2201] [Nonflammable gas], Polymerofmethyloxiraneandoxirane;polyoxyethylene-oxy-propylene;proxanoltsl-3;rc102;ucon75-h-1400;pluronic F-127 cell culture tested;PLURONIC F-127, PROTEIN GRADEDetergent, 10% Solution;pluronic F-68 plant cell culture tested
WANOL F3156 is a nonionic detergent widely used to solubilize hydrophobic molecules such as cell-permeable AM esters of Fluo-4, Fluorica-8 calcium indicators, and Di-4-ANEPS, Di-8-ANEPS potentiometric probes and facilitate their loading into cells. W
WANOL F3156 is a BHT-free polyether polyol.
WANOL F3156 has low functionality, low activity and high molecular weight.
WANOL F3156 is produced by reacting a starter molecule such as glycerol with ethylene oxide and propylene oxide to form long polyether chains with reactive hydroxyl end groups.
These hydroxyl groups allow it to react with isocyanates during polyurethane formation.
WANOL F3156 makes it essential in foam and elastomer chemistry.
WANOL F3156 is usually a viscous liquid that is clear to slightly yellow and easy to process in industrial mixing systems.
It is designed for stable storage and consistent behavior during manufacturing.
WANOL F3156 makes it suitable for large-scale industrial use.
WANOL F3156 is best understood as a polyol building block used to produce polyurethane materials with tailored mechanical properties such as softness, flexibility, or insulation performance.
Its main role is to determine the final structure and performance of foam products.
WANOL F3156 makes it a key material in polymer engineering.
WANOL F3156 behaves as a reactive polymer intermediate whose main function is to build structure during polyurethane formation rather than act as a finished material itself.
It becomes part of the final polymer network after reacting with isocyanates.
WANOL F3156 makes it fundamentally a structure-forming raw material.
Its performance depends strongly on molecular weight, functionality, and hydroxyl content, which determine how densely it can crosslink in polyurethane systems.
Higher or lower values of these parameters change the flexibility or rigidity of the final foam.
WANOL F3156 makes it a key formulation control parameter.
During processing, it is typically used in carefully controlled ratios with catalysts, surfactants, and blowing agents to regulate reaction speed and foam expansion behavior.
Small deviations in formulation can significantly affect foam quality and stability.
WANOL F3156 makes precision important in industrial production.
In foam morphology development, it influences cell size distribution and internal structure of polyurethane foams, which directly affects properties such as cushioning, insulation efficiency, and mechanical strength.
More uniform structures generally lead to better performance and durability.
WANOL F3156 makes it important in material microstructure control.
WANOL F3156 is selected for its consistent batch-to-batch performance, which ensures predictable processing behavior and reproducible material properties in large-scale manufacturing.
This reliability is critical for commercial foam production systems.
WANOL F3156 makes it valuable in quality-controlled polymer production.
In application engineering, it can be adjusted within formulations to produce a wide range of material properties, from soft flexible foams to semi-rigid structural foams depending on the overall system design.
This versatility allows it to be used across multiple industries with different performance requirements.
WANOL F3156 makes it a flexible base material in polyurethane technology.
WANOL F3156 is a controlled-performance polyether polyol designed to behave predictably in polyurethane reaction systems, where its main role is to determine how the final polymer network forms during foam production rather than function as a finished material itself.
It participates directly in the chemical network formation once combined with isocyanates under catalytic conditions.
This makes it a foundational structure-building component in polymer chemistry.
Its behavior in formulations is strongly influenced by its hydroxyl functionality and molecular architecture, which control how many reactive sites are available for crosslinking and therefore determine the rigidity or flexibility of the final polyurethane product.
Small changes in these parameters can significantly shift foam characteristics.
This makes it a key tuning variable in material design.
During foam production, it contributes to reaction kinetics balance between gelling (polymer formation) and blowing (gas formation), which directly affects foam expansion, density, and internal structure stability.
Proper balance is required to avoid collapse or uneven foam formation.
This makes it critical in foam process control.
In industrial manufacturing environments, WANOL F3156 is valued for its consistent viscosity and predictable processing behavior, which allows stable mixing with catalysts, surfactants, and isocyanates in automated production systems.
This consistency ensures uniform product quality across large batches.
This makes it important for scalable industrial production.
In material engineering, it helps define final mechanical performance such as compression strength, elasticity, and thermal resistance depending on formulation design and curing conditions.
These properties determine how the final foam performs in real-world applications.
WANOL F3156 makes it essential in performance material development.
In broader application design, it is used as a base building block that can be adapted into a wide range of polyurethane systems, from ultra-soft cushioning foams to more rigid structural materials.
Its versatility comes from how it interacts with other formulation components.
WANOL F3156 makes it a flexible platform material in polyurethane technology.
Melting point: 57–61 °C
Boiling point: >200 °C (lit.)
Density: 1.095 g/mL at 25 °C
bulk density: 1050 kg/m3
vapor density: >1 (vs air)
vapor pressure: <0.3 mm Hg (20 °C)
refractive index: n20/D 1.466
Flash point: >230 °F
storage temp.: 2–8°C
solubility: H2O: soluble below 70 °C
form: solution
color: APHA ≤120 (50/50 in CH3OH)
pH: 5.0–7.5 (100 g/L in H2O)
pH Range: 5.0–7.5
biological source: synthetic
Viscosity: 850 cP (25 °C, Brookfield)
Water Solubility: miscible with water
λmax: λ 260 nm, Amax ≤0.3
λmax: λ 280 nm, Amax ≤0.2
Merck: 13,7644
Hydrophilic-Lipophilic Balance (HLB): 18–23
Cosmetics Ingredients Functions: SURFACTANT - CLEANSING; SURFACTANT - HYDROTROPE; CLEANSING; SOLVENT; HUMECTANT; EMULSION STABILISING; BINDING; SURFACTANT - EMULSIFYING; VISCOSITY CONTROLLING
InChI: 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChIKey: RVGRUAULSDPKGF-UHFFFAOYSA-N
SMILES: O2C(C2)C.O1CC1
LogP: -1.293 (est)
WANOL F3156 generally occur as white, waxy, free-flowing prilled granules, or as cast solids.
They are practically odorless and tasteless.
At room temperature, poloxamer 124 occurs as a colorless liquid.
WANOL F3156 is nonionic polyoxyethylene–polyoxypropylene copolymers used primarily in pharmaceutical formulations as emulsifying or solubilizing agents.
The polyoxyethylene segment is hydrophilic while the polyoxypropylene segment is hydrophobic.
All of the WANOL F3156 is chemically similar in composition, differing only in the relative amounts of propylene and ethylene oxides added during manufacture.
Their physical and surface-active properties vary over a wide range and a number of different types are commercially available.
WANOL F3156 is used as emulsifying agents in intravenous fat emulsions, and as solubilizing and stabilizing agents to maintain the clarity of elixirs and syrups.
WANOL F3156 may also be used as wetting agents; in ointments, suppository bases, and gels; and as tablet binders and coatings.
WANOL F3156 has also been used as an emulsifying agent for fluorocarbons used as artificial blood substitutes, and in the preparation of solid-dispersion systems.
More recently,Polyethylene-polypropylene glycol has found use in drug-delivery systems.
WANOL F3156 is administered orally as a wetting agent and stool lubricant in the treatment of constipation; it is usually used in combination with a laxative such as danthron.
WANOL F3156 may also be used therapeutically as wetting agents in eye-drop formulations, in the treatment of kidney stones, and as skin-wound cleansers.
WANOL F3156 and 407 are used in solutions for contact lens care.
WANOL F3156 is considered a moderate-hazard industrial chemical because it is a reactive polymer precursor used in controlled chemical synthesis, although it is not highly toxic under normal handling conditions.
Most hazards arise from exposure during processing rather than inherent acute toxicity.
WANOL F3156 makes industrial safety procedures necessary.
Direct contact with the material may cause mild irritation to skin or eyes, especially after prolonged or repeated exposure.
WANOL F3156 effect is related to its chemical reactivity and formulation nature rather than corrosive behavior.
This makes protective gloves and goggles important during handling.
Inhalation of vapors, aerosols, or mist generated during heating or spraying operations may lead to temporary respiratory irritation, particularly in poorly ventilated industrial environments.
While not highly volatile, processing conditions can increase exposure risk.
WANOL F3156 makes ventilation and fume control important.
WANOL F3156 must also be handled carefully to prevent environmental release, since large-scale discharge of polyol materials can affect wastewater systems and require proper treatment before disposal.
WANOL F3156 is not intended for direct environmental exposure without processing controls.
This makes waste management and containment procedures necessary.
WANOL F3156 is stable materials. Aqueous solutions are stable in the presence of acids, alkalis, and metal ions. However, aqueous solutions support mold growth.
WANOL F3156 works as part of a chemical reaction system where it reacts with isocyanates to form polyurethane networks that define the structure of foam materials.
The balance between components controls density, hardness, and elasticity.
WANOL F3156 makes it critical for foam formulation design.
In flexible foam systems, it contributes to softness, cushioning ability, and elastic recovery after compression, which are important in seating and bedding materials.
WANOL F3156 helps create materials that feel comfortable while maintaining durability.
WANOL F3156 makes it important for comfort-based products.
In rigid foam systems, it helps form closed-cell structures that trap gas and provide thermal insulation, making the material lightweight and energy efficient.
These structures are widely used in construction and appliance insulation.
WANOL F3156 makes it valuable for energy-saving applications.
It also provides consistent processing behavior during manufacturing, allowing predictable reaction times and stable foam formation when combined with catalysts and additives.
This ensures uniform product quality in large-scale production.
This makes it important in industrial process control.
WANOL F3156 is a key tuning component in polyurethane chemistry that controls physical performance rather than acting as a final product itself.
Small formulation changes can significantly affect final material properties.
WANOL F3156 makes it a central design material in foam engineering.
Uses Of WANOL F3156:
Hard and soft surface cleaners, defoamers in coatings and water treatment.
Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.
WANOL F3156 is used as a polyol raw material in polyurethane production systems where it reacts with isocyanates to form foam and elastomer structures.
It provides the chemical foundation for building polymer networks.
WANOL F3156 makes it a core industrial feedstock.
In furniture and bedding applications, it is used to produce flexible foam for mattresses, cushions, and upholstery materials.
These foams require a balance of softness and long-term resilience.
WANOL F3156 makes it important in comfort products.
In automotive manufacturing, it is used in seat cushions, interior padding, and vibration-absorbing foam components.
These materials improve comfort and reduce noise and vibration inside vehicles.
WANOL F3156 makes it useful in transportation engineering.
In construction, it is used to produce rigid insulating foam panels and building insulation materials.
These foams help reduce heat loss and improve energy efficiency in buildings.
This makes it important in thermal insulation systems.
WANOL F3156 is also used in specialty molded polyurethane parts such as packaging foam, shoe soles, and technical components.
These applications require customized mechanical properties like flexibility or hardness.
WANOL F3156 makes it valuable in engineered material production.
WANOL F3156 is used as a polyether polyol raw material in polyurethane systems, where it reacts with isocyanates to form polymer networks that define the final physical properties of foam or elastomer products.
It provides the structural foundation of polyurethane materials.
This makes it a core feedstock in polymer manufacturing.
In furniture and bedding production, it is used to create flexible polyurethane foams for mattresses, cushions, and upholstery, where softness, comfort, and resilience are required.
These materials must maintain shape and elasticity over long-term use.
WANOL F3156 makes it important in comfort product engineering.
In automotive applications, it is used in seat cushioning, interior padding, and vibration-damping components, where both comfort and mechanical durability are required.
WANOL F3156 helps improve driving comfort and reduces noise and vibration inside vehicles.
WANOL F3156 makes it valuable in automotive interior design.
In construction and insulation materials, it is used to produce rigid foam systems for thermal insulation panels and energy-efficient building components.
These foams reduce heat transfer and improve energy conservation in buildings.
WANOL F3156 makes it important in energy efficiency applications.
WANOL F3156 is also used in industrial molded parts, packaging foams, and specialty elastomer systems, where customized hardness, flexibility, or durability is required.
It allows manufacturers to engineer materials for specific mechanical performance needs.
WANOL F3156 makes it useful in advanced material design.
WANOL F3156 is used as a polyether polyol raw material in polyurethane production systems, where it reacts with isocyanates to form the polymer backbone of foam and elastomer materials.
It provides the structural framework that defines final material properties.
WANOL F3156 makes it a core industrial feedstock.
In furniture and bedding applications, it is used to produce flexible polyurethane foams for mattresses, cushions, and upholstered furniture, where comfort, softness, and long-term resilience are required.
These foams must maintain shape while providing cushioning support.
This makes it essential in comfort material manufacturing.
In automotive applications, it is used in seat cushions, headrests, interior padding, and vibration-damping components, where mechanical stability and energy absorption are important.
It improves passenger comfort and reduces noise and vibration.
WANOL F3156 makes it valuable in vehicle interior engineering.
In construction and insulation, it is used to produce rigid foam insulation panels and energy-efficient building materials, where low thermal conductivity and structural stability are required.
These foams help reduce energy loss in buildings and equipment.
WANOL F3156 makes it important in thermal insulation systems.
WANOL F3156 is also used in industrial molded polyurethane products such as packaging foams, protective materials, and engineered elastomer parts, where customized hardness and flexibility are required.
It allows precise control over mechanical behavior in final products.
WANOL F3156 makes it useful in advanced polymer manufacturing.
Safety Profile Of WANOL F3156:
When heated to decomposition it emits acrid smoke and irritating fumes.
Polyethylene-polypropylene glycol is used in a variety of oral, parenteral, and topical pharmaceutical formulations, and are generally regarded as nontoxic and nonirritant materials.Polyethylene-polypropylene glycol is not metabolized in the body.
Animal toxicity studies, with dogs and rabbits, have shown Polyethylene-polypropylene glycol to be nonirritating and nonsensitizing when applied in 5% w/v and 10% w/v concentration to the eyes, gums, and skin.
WANOL F3156 is considered a low-to-moderate hazard industrial chemical, but it still requires careful handling because it is a reactive polymer precursor.
Its main risks are related to exposure and industrial processing conditions rather than high toxicity.
This makes standard chemical safety practices necessary.
Direct contact with the liquid can cause mild skin or eye irritation, especially with prolonged or repeated exposure.
Eye contact may cause discomfort and requires immediate rinsing.
WANOL F3156 makes protective gloves and goggles important during handling.
Inhalation of vapors or aerosols during heated processing may cause temporary respiratory irritation, particularly in poorly ventilated environments.
Although it is not highly volatile, mist formation can increase exposure risk.
This makes ventilation important in industrial settings.
It should also be handled carefully to avoid environmental release, since large quantities may contribute to pollution if not properly contained or treated.
WANOL F3156 is not intended for direct release into water or soil systems.
This makes proper disposal and waste management necessary.
WANOL F3156s hazards are mainly practical and exposure-related rather than severe toxic effects, and it is safe when handled according to industrial guidelines.
Basic protective equipment and controlled processing conditions are sufficient for safe use.
WANOL F3156 makes it manageable in regulated industrial environments.
