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WILFARIN PA-1695

CAS:    57-10-3
MF:    C16H32O2
MW:    256.42
EINECS:    200-312-9

Definition
WILFARIN PA-1695 is a saturated long-chain fatty acid with a 16-carbon backbone. 
WILFARIN PA-1695 is a metabolite found in the aging mouse brain. 
WILFARIN PA-1695 is found naturally in palm oil and palm kernel oil, as well as in butter, cheese, milk and meat.    
WILFARIN PA-1695 is used in oral and topical pharmaceutical formulations and is generally regarded as nontoxic and nonirritant at the levels employed as an excipient. 
However, WILFARIN PA-1695 is reported to be an eye and skin irritant at high levels and is poisonous by intravenous administration.
WILFARIN PA-1695 is used in oral and topical pharmaceutical formulations. 
WILFARIN PA-1695 has been used in implants for sustained release of insulin in rats.
WILFARIN PA-1695 is incompatible with strong oxidizing agents and bases.
WILFARIN PA-1695) is a fatty acid with a 16-carbon chain. 
WILFARIN PA-1695 is the most common saturated fatty acid found in animals, plants and microorganisms.
WILFARIN PA-1695's chemical formula is CH3(CH2)14COOH, and its C:D (the total number of carbon atoms to the number of carbon-carbon double-bonds) is 16:0. 
WILFARIN PA-1695 is a major component of the oil from the fruit of oil palms (palm oil), making up to 44% of total fats. 
Meats, cheeses, butter, and other dairy products also contain palmitic acid, amounting to 50–60% of total fats. 
Palmitates are the salts and esters of WILFARIN PA-1695. 
The palmitate anion is the observed form of WILFARIN PA-1695 at physiologic pH (7.4).

WILFARIN PA-1695 Chemical Properties
Melting point: 61-62.5 °C(lit.)
Boiling point: 351.5 °C
Density: 0.852 g/mL at 25 °C(lit.)
Vapor pressure: 10 mm Hg ( 210 °C)
Refractive index: 1.4273
FEMA: 2832 | PALMITIC ACID
Fp: >230 °F
Storage temp.: room temp
Solubility: chloroform: 0.5 M, clear, colorless
Form: Flakes
pka: 4.78±0.10(Predicted)
Color: White or almost white
Water Solubility: insoluble
Merck: 14,6996
JECFA Number: 115
BRN: 607489
Stability: Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.
InChIKey: IPCSVZSSVZVIGE-UHFFFAOYSA-N
CAS DataBase Reference :57-10-3(CAS DataBase Reference)
NIST Chemistry Reference: WILFARIN PA-1695 (57-10-3)
EPA Substance Registry System: WILFARIN PA-1695 (57-10-3)

Uses
WILFARIN PA-1695 is used in the following products: washing & cleaning products, coating products, finger paints, fillers, putties, plasters, modelling clay, polishes and waxes, air care products, plant protection products and cosmetics and personal care products.
Other release to the environment of WILFARIN PA-1695 is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
WILFARIN PA-1695 is used in the following products: washing & cleaning products, polishes and waxes, cosmetics and personal care products, laboratory chemicals, adhesives and sealants and pH regulators and water treatment products.
WILFARIN PA-1695 is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and formulation of mixtures and/or re-packaging.
WILFARIN PA-1695 is used for the manufacture of: textile, leather or fur.

Release to the environment of WILFARIN PA-1695 can occur from industrial use: formulation of mixtures and in processing aids at industrial sites.
Other release to the environment of WILFARIN PA-1695 is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
WILFARIN PA-1695 is used in the following products: washing & cleaning products, leather treatment products, polymers, textile treatment products and dyes, pH regulators and water treatment products and lubricants and greases.
WILFARIN PA-1695 is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
WILFARIN PA-1695 is used for the manufacture of: textile, leather or fur.
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and as processing aid.

WILFARIN PA-1695 is mainly used to produce soaps, cosmetics, and release agents. 
These applications utilize sodium palmitate, which is commonly obtained by saponification of palm oil. 
To this end, palm oil, rendered from the coconut palm nut, is treated with sodium hydroxide (in the form of caustic soda or lye), which causes hydrolysis of the ester groups. 
This procedure affords glycerol and sodium palmitate.
Because WILFARIN PA-1695 is inexpensive and adds texture to processed foods (convenience food), palmitic acid and its sodium salt find wide use including foodstuffs. 
Sodium palmitate is permitted as a natural additive in organic products.
Hydrogenation of WILFARIN PA-1695 yields cetyl alcohol, which is used to produce detergents and cosmetics.
Recently, a long-acting antipsychotic medication, paliperidone palmitate (marketed as INVEGA Sustenna), used in the treatment of schizophrenia, has been synthesized using the oily palmitate ester as a long-acting release carrier medium when injected intramuscularly. 
The underlying method of drug delivery is similar to that used with decanoic acid to deliver long-acting depot medication, in particular, neuroleptics such as haloperidol decanoate.

Occurrence and production
WILFARIN PA-1695 was discovered by Edmond Frémy in 1840, in saponified palm oil.
This remains the primary industrial route for WILFARIN PA-1695's production, with the triglycerides (fats) in palm oil being hydrolysed by high temperature water and the resulting mixture fractionally distilled.
WILFARIN PA-1695 is produced by a wide range of other plants and organisms, typically at low levels. 
WILFARIN PA-1695 is present in butter, cheese, milk, and meat, as well as cocoa butter, olive oil, soybean oil, and sunflower oil.
WILFARIN PA-1695 contain 95% palmitic acid. 
The cetyl ester of palmitic acid (cetyl palmitate) occurs in spermaceti.

Synonyms
palmitic acid
Hexadecanoic acid
57-10-3
Cetylic acid
palmitate
n-Hexadecanoic acid
Hexadecylic acid
Hydrofol
n-Hexadecoic acid
1-Pentadecanecarboxylic acid
Palmitinic acid
Pentadecanecarboxylic acid
C16 fatty acid
hexadecanoate
hexaectylic acid
1-Hexyldecanoic Acid
hexadecoic acid
Industrene 4516
Emersol 140
Emersol 143
Hystrene 8016
Hystrene 9016
Palmitinsaeure
Palmitic acid, pure
FEMA No. 2832
Palmitic acid 95%
Kortacid 1698
Loxiol EP 278
Palmitic acid (natural)
Hydrofol Acid 1690
Prifac 2960
Fatty acids, C14-18
Pristerene 4934
Edenor C16
Lunac P 95KC
C16:0
Lunac P 95
Lunac P 98
Cetyl acid
HSDB 5001
AI3-01594
NSC 5030
Pristerene-4934
Palmitic acid (NF)
Glycon P-45
CHEBI:15756
NSC5030
Prifac-2960
NSC-5030
Hexadecanoic acid (9CI)
MFCD00002747
Palmitic acid (7CI,8CI)
CHEMBL82293
CH3-[CH2]14-COOH
IMEX C 1498
2V16EO95H1
n-hexadecoate
LMFA01010001
PA 900
67701-02-4
FA 16:0
FA 1695
1-hexyldecanoate
NCGC00164358-01
DSSTox_CID_1602
pentadecanecarboxylate
Hexadecanoic acid 10 microg/mL in Acetonitrile
DSSTox_RID_76229
DSSTox_GSID_21602
C16H32O2
PLM
palmic acid
Hexadecanoate (n-C16:0)
CAS-57-10-3
CCRIS 5443
SR-01000944716
EINECS 200-312-9
Palmitic acid [USAN:NF]
BRN 0607489
palmitoate
Hexadecoate
Palmitinate
palmitic-acid
palmitoic acid
Hexadecanoicacid
Aethalic acid
UNII-2V16EO95H1
Hexadecanoic acid Palmitic acid
2hmb
2hnx
Fatty acid pathway
Palmitic acid_jeyam
Palmitic Acid, FCC
Kortacid 1695
Palmitic acid_RaGuSa
Univol U332
Prifrac 2960
Hexadecanoic acid anion
3v2q
Palmitic acid, >=99%
bmse000590
Epitope ID:141181
EC 200-312-9
CETYL ACID [VANDF]
PALMITIC ACID [II]
PALMITIC ACID [MI]
SCHEMBL6177
PALMITIC ACID [DSC]
PALMITIC ACID [FCC]
PALMITIC ACID [FHFI]
PALMITIC ACID [HSDB]
PALMITIC ACID [INCI]
PALMITIC ACID [USAN]
4-02-00-01157 (Beilstein Handbook Reference)
FAT
WLN: QV15
P5585_SIGMA
PALMITIC ACID [VANDF]
PALMITIC ACID [MART.]
GTPL1055
QSPL 166
PALMITIC ACID [USP-RS]
PALMITIC ACID [WHO-DD]
(1(1)(3)C)hexadecanoic acid
DTXSID2021602
1b56
HMS3649N08
Palmitic acid, analytical standard
Palmitic acid, BioXtra, >=99%
Palmitic acid, Grade II, ~95%
HY-N0830
Palmitic acid, natural, 98%, FG
ZINC6072466
Tox21_112105
Tox21_201671
Tox21_302966
AC9381
BBL011563
BDBM50152850
PALMITIC ACID [EP MONOGRAPH]
s3794
STL146733
EDENOR C 16-98-100
Palmitic acid, >=95%, FCC, FG
AKOS005720983
Tox21_112105_1
CCG-267027
CR-0047
DB03796
Palmitic acid, for synthesis, 98.0%
SURFAXIN COMPONENT PALMITIC ACID
NCGC00164358-02
NCGC00164358-03
NCGC00256424-01
NCGC00259220-01
BP-27917
LUCINACTANT COMPONENT PALMITIC ACID
Palmitic acid, purum, >=98.0% (GC)
SY006518
CS-0009861
FT-0626965
FT-0772579
P0002
P1145
Palmitic acid, SAJ first grade, >=95.0%
EN300-19603
A14813
C00249
D05341
Palmitic acid, Vetec(TM) reagent grade, 98%
Palmitic acid, >=98% palmitic acid basis (GC)
A831313
HEXADECANOIC ACID-13C16 (ALGAL SOURCE) (
Q209727
SR-01000944716-1
SR-01000944716-2
BA71C79B-C9B1-451A-A5BE-B480B5CC7D0C
PALMITIC ACID (CONSTITUENT OF SPIRULINA) [DSC]
F0001-1488
Z104474418
PALMITIC ACID (CONSTITUENT OF FLAX SEED OIL) [DSC]
PALMITIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]
Palmitic acid, certified reference material, TraceCERT(R)
PALMITIC ACID (CONSTITUENT OF BORAGE SEED OIL) [DSC]
Palmitic acid, European Pharmacopoeia (EP) Reference Standard
PALMITIC ACID (CONSTITUENT OF EVENING PRIMROSE OIL) [DSC]
Palmitic acid, United States Pharmacopeia (USP) Reference Standard
Palmitic acid, Pharmaceutical Secondary Standard; Certified Reference Material
Sodium Palmitate, Palmitic acid sodium salt, Sodium hexadecanoate, Sodium pentadecanecarboxylate, HSDB 759

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