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ZINC OMADINE

Zinc Omadine is a coordination complex of zinc. 
Zinc Omadine has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties
Zinc Omadine is used in the treatment of seborrhoeic dermatitis and dandruff.

CAS  NUMBER: 13463-41-7

EC NUMBER: 236-671-3

MOLECULAR FORMULA: C10H8N2O2S2Zn

MOLECULAR WEIGHT: 317.7

IUPAC NAME: zinc;1-oxidopyridine-2-thione


Zinc Omadine is the most popular anti-dandruff ingredient in the world
Zinc Omadine is offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products. 

Zinc Omadine helps remove dandruff
Zinc Omadine offers enhanced scalp health

Zinc Omadine acts as an anti-dandruff and odor-controlling agent. 
Zinc Omadine offers bactericide-fungicide efficacy

Zinc Omadine relieves flaking symptoms of dandruff, enhances substantivity to the skin and hair and offers weightless styling. 
Zinc Omadine is used in shampoo, conditioner, hair treatment formulation and skincare products.

Zinc Omadine is the most popular anti-dandruff ingredient in the world.
Zinc Omadine offers bactericidal-fungicide activity in shampoos, conditioners and non-rinsing products.

Zinc Omadine helps remove dandruff
Zinc Omadine offers enhanced scalp health

Zinc Omadine is a coordination complex of the zinc ion and pyrithione
Zinc Omadine is a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects. 

Zinc Omadine is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products. 
Zinc Omadine Powder antimicrobial is an effective broad spectrum bio-cide for the preservation of products against spoilage from fungi, yeasts, algae and bacteria. 
The product is the technical grade active substance more commonly named zinc pyrithione.

Zinc Omadine is particularly effective as a single active dry-film preservative for:
– Architectural and industrial paint and coatings.
– Construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds.
– Building materials including ceilings, ceiling tiles, walls and internal partitions.
– Textiles including apparel and home textiles.
– Thermoplastic polymers such as PVC, silicone, polyolefin, polyurethane and acrylics.
– Plastics applications for the control of mildew and bacteria in carpeting, carpet underlay, cushion and mattress foam, athletic flooring and mats, components of footwear and sponges.


USES
Medicine:
Zinc Omadine can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Omadine also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Omadine's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.

Paint:
Because of its low solubility in water (8 ppm at neutral pH), Zinc Omadine is suitable for use in outdoor paints and other products that protect against mildew and algae. 
Zinc Omadine is an algaecide. 
Zinc Omadine is chemically incompatible with paints relying on metal carboxylate curing agents. 
When Zinc Omadine is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed. 
Zinc Omadine is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges:
Zinc Omadine is an antibacterial treatment for household sponges 

Clothing:
Zinc Omadine is used to prevent microbe growth in polyester.
Textiles with applied Zinc Omadine protect against odor-causing microorganisms.

Structure of the Compound:
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. 
In the crystalline state, Zinc Omadine exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.
Zinc Omadine is the conjugate base derived from 2-mercaptopyridine-N-oxide, a derivative of pyridine-N-oxide

Zinc Omadine is also known as Zinc pyrithione
Zinc Omadine is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes, and in a wide range of finished articles made from these starting materials. 

Zinc Omadine acts to prevent the growth of bacteria, fungi, mildew, and algae that can cause various types of deterioration such as discoloration, staining, odors, etc.
Zinc Omadine is used to preserve a wide variety of food/drinking water contact, and non-food contact articles such as: adhesives; carpet fibers; carpet backings; rubber or rubber-backed bath mats; foam underlay for carpets; synthetic, non-leather materials; foam stuffing for cushions and mattresses; wire and cable insulation; vinyl, linoleum, tile and other synthetic floor coverings; wall coverings; plastic furniture; athletic flooring and mats; mattress liners, covers or ticking; molding; mats; gaskets; weather stripping; coated fabrics for furniture cushions, boat covers, tents; tarpaulins and awnings; rubber gloves (non-surgical); garbage bags, cans, and other refuse containers; bathtub appliques; garden hose; pipe (non-potable water); ductwork; air filters; air filtration components and media for industrial, hospital, residential, and commercial heating and cooling; conveyor belts; shower curtains; sponge or fiber mops; household use sponges; toilet brush receptacles; toothbrus receptacles (non-bristle contact); scrub brushes (non-medical); sink mats and drain boards; storage containers; soap dish holders; towel bars; components of uppers in footwear.

Zinc Omadine is used in various products in the cosmetic industry.
Zinc Omadine is one of the zinc salts that is often used in conditioners, shampoos, face powders, cleaning products, eyeliners, cleaning and skin care products.

The functions of Zinc Pyrithione are:
-Zinc Omadine fights dandruff
-Zinc Omadine controls sebum production
-Zinc Omadine helps the hair to be easily combed, soft, shiny and voluminous.
-Zinc Omadine prevents the growth of microorganisms in cosmetic products

Zinc Omadine is used by consumers, by professional workers (widespread uses), in formulation or re-packing and in manufacturing.
Zinc Omadine is used for the manufacture of chemicals

Biocidal Uses
Zinc Omadine is used for: disinfection, product preservation, preservation films, preservation of fibres, leather, rubber, or polymers, preservation for construction materials, preventing fouling.

Consumer Uses
Zinc Omadine is used in the following products: cosmetics and personal care products.

Widespread uses
Zinc Omadine is used in the following products: cosmetics and personal care products and laboratory chemicals.

Zinc Omadine is used in the following areas: 
-scientific research
-development
-health services

Formulation or re-packing:
Zinc Omadine is used in the following products: cosmetics, personal care products and biocides (e.g. disinfectants, pest control products).

Zinc Omadine, also commonly known as zinc pyrithione, has antibacterial, antimicrobial, and antifungal properties
Zinc Omadine can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


PHYSICAL PROPERTIES: 

-Molecular Weight: 317.7        

-Exact Mass: 315.931862    

-Monoisotopic Mass: 315.931862    

-Topological Polar Surface Area: 117 Ų    

-Melting Point: approximate 240℃

-Density: 1.782 g/cm3

-Vapor Pressure: 0Pa

-Storage Temperature: Sealed in dry,Room Temperature

-Solubility: almost transparency in Pyridine

-Form: Powder

-Color: White to Orange to Green

-Water Solubility: Insoluble

-LogP: 0.9

-Surface Tension: 73mN/m


Zinc Omadine is the pyrithione complexes of zinc bromide
Zinc Omadine used as a topical antifungal or antibacterial agent. 

At room temperature Zinc Omadine is white to yellow crystalline powder. 
Zinc Omadine has slight characteristic odor


CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 0    

-Hydrogen Bond Acceptor Count: 4    

-Rotatable Bond Count: 0

-Heavy Atom Count: 17

-Formal Charge: 0    

-Complexity: 162    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 3    

-Compound Is Canonicalized: Yes


Zinc Omadine is insoluble in water. 
Zinc Omadine's solubility in water is 15mg/kg

Zinc Omadine react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures
Zinc Omadine is not stable to acids and bases. 

Zinc Omadine is not compatible with EDTA
Non-ionic surfactants make Zinc Omadine partially deactivated. 

Uses
Zinc Omadine is used in shampoo for dandruff
Zinc Omadine can inhibit Gram positive and negative bacteria and mold growth

Zinc Omadine delays hair aging
Zinc Omadine controls white hair and hair loss generation. 

Zinc Omadine is also used as a cosmetic preservative, oil, paint and biocide.
Zinc Omadine has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .

Pharmaceutical Applications
Zinc Omadine is a regulator of keratinization

Zinc Omadine has antimicrobial properties and ketoconazole is an antifungal agent
Zinc Omadine is directly cytotoxic and has antimicrobial effects. 

Zinc Omadine is found in many shampoos
Zinc Omadine is the active ingredient in several shampoos used to control dandruff and seborrheic dermatitis and is also effective in the therapy of tinea versicolor. 

Zinc Omadine is the most popular anti-dandruff ingredient in the world
Zinc Omadine acts as an anti-dandruff and odor-controlling agent. 

Zinc Omadine is used in shampoo, conditioner, hair treatment formulation and skincare products.
Zinc Omadine helps remove dandruff

Zinc Omadine can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Omadine also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.

Zinc Omadine is an antibacterial treatment for household sponges
Zinc Omadine is also known as Zinc pyrithione

Zinc Omadine is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes, and in a wide range of finished articles made from these starting materials. 
Zinc Omadine helps the hair to be easily combed, soft, shiny and voluminous.
Zinc Omadine is used for the manufacture of chemicals


SYNONYMS: 

Zinc pyridinethione
Zinc Omadine
ZnPT
Pyrithione zinc derivative
2-Mercaptopyridine N-Oxide Zinc Salt
zinc;1-oxidopyridine-2-thione
2-Pyridinethiol 1-Oxide Zinc Salt
NSC-290409
Zinc pyrithione (JAN)
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4)-
ZINC PYRITHIONE
Zinc pyrethion
Zinc pyrithone
Sebulon Shampoo
zinc 1-oxidopyridine-2-thione
zinc-2-pyridinethione-1-oxide
Omadine Zinc
Vancide P
Vancide ZP
Zinc - pyrion
Head and Shoulders
Zn - pyrion
HEAD & SHOULDERS CONDITIONER
ZINCPYRITHIONE
Zinc pyrithione(USAN
Pyrithione zinc
PYRITHIONE ZINC
SCHEMBL136623
Zinc 2-pyridinethiol 1-oxide
zinc 1-oxido-2-pyridinethione
PYRITHIONE ZINC 
ZINC PYRITHIONE 
ZINC PYRITHIONE
ZINC PYRITHONE
GTPL2597
R953O2RHZ5
Zinc pyridine-2-thiol-1-oxide
PYRITHIONE ZINC 
ZINC PYRITHIONE 
CHEMBL1200471
CHEMBL3392049
PYRITHIONE ZINC
Zinc 2-mercaptopyridine N-oxide
CHEBI:32076
PYRITHIONE ZINC
zinc 1-oxidanidylpyridine-2-thione
zinc 1-oxidopyridin-1-ium-2-thiol
NSC290409
PYRITHIONE ZINC
AKOS015891514
AKOS015951268
PYRITHIONE ZINC DERIVATIVE
Bis(2-pyridylthio) Zinc 1,1'-Dioxide
NCGC00091933-02
AC-13775
Bis[1-hydroxy-2(1H)-pyridinethionato]zinc
Zinc, bis(2-pyridylthio)-, 1,1'-dioxide
Zinc, bis(2-pyridylthio)-, N,N'-dioxide
FT-0636895
M0633
Zinc, bis(2-pyridinylthio)-, N,N'-dioxide
{Bis[1-hydroxy-2(1H)-pyridinethionato]zinc}
D01938
Bio Boost 2300EX
Blo Boost 2300EX
Pyrithione zinc
Pyrithione zinc
pyrithione zinc
Pyrithione zinc (Zinc pyrithione)
Pyrithion-Zink (Zink-Pyrithion) (de)
Pyrithione zinc (Zinc pyrithione) (no)
Pyrithione zincique (pyrithione de zinc) (fr)
1-oxidopyridine-6-thiolate, zinc (II) cation
2-Mercaptopyridine N-Oxide Zinc Salt
Bis [1-hydroxy-2(1H)-pyridinethionato-O,S](T-4)-zinc
bis(1-hydroxy-2(1h)-pyridinethionato)zinc
bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4) zinc
Bis(1-hydroxy-2(1H)-pyridinthionato-O,S) zinc
bis(2-pyridylthio)zinc 1,1'-dioxide
bis[1-hydroxy-2-(1H)-pyridine-thionato]zinc
Kopthione Zn
Mercaptopyridine N-oxide zinc salt, Pyrithione
Mercaptopyridine N-oxidezinc salt
Pyrithione zinc
pyrithione zinc
Zinc pyrithione
1-Hydroxypyridine-2-thione zinc salt
2-Pyridinethiol, 1-oxide, zinc salt (2:1) 
Bis(1-oxyde de -2-pyridinethiolate) et de zinc
Mercaptopyridine N-oxide zinc salt
MFCD00067336 
Pyrithione
Pyrithione zinc
ZH0950000
Zinc bis(2-pyridinethiolate 1-oxide)
Zinc bis(pyridine-2-thiolate 1-oxide)
Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-
Zinkbis(2-pyridinthiolat-1-oxid)
(T-4)-bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
[13463-41-7] [RN]
1698050-37-1 [RN]
1-Hydroxypyridine-2-thione zinc
2(1H)-Pyridinethione, 1-hydroxy-, zinc complex
2-Mercaptopyridine 1-oxide zinc salt
2-Mercaptopyridine-1-oxide, zinc salt
2-Pyridinethiol-1-oxide, zinc salt
Biocut ZP
Bis((1-oxidopyridin-2-yl)thio)zinc
bis(1-hydroxy-2(1H)-pyridinethionato)zinc
Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc
bis(2-pyridinethiol-1-oxide)zinc
bis(2-pyridylthio)zinc 1,1'-dioxide
BIS[(1-OXIDOPYRIDIN-1-IUM-2-YL)SULFANYL]ZINC
Breck One Dandruff Shampoo
Danex
Evafine P 50
Finecide ZPT
Head and Shoulders
Hokucide ZPT
Niccanon SKT
Omadine Zinc
Pyrithion-Zink
QA-7225
Sebulon Shampoo
Tomicide Z 50
Top Brass
Vancide P
Vancide ZP
Wella Crisan
Zinc - pyrion
Zinc 1-hydroxy-2-pyridinethione
Zinc 1-hydroxypyridine-2-thione
Zinc 2-mercaptopyridine N-oxide
Zinc 2-pyridinethiol 1-oxide
Zinc 2-pyridinethiol-1-oxide
Zinc bis(2-pyridylthio)-N-oxide
Zinc bis(2-thioxopyridin-1(2H)-olate)
Zinc omadine
Zinc pt
Zinc pyrethion
Zinc pyridine-2-thiol 1-oxide
Zinc pyridine-2-thiol-1-oxide
zinc pyridinethione
Zincon Dandruff Shampoo
Zincpyrithione
ZnPT
ZPT


 

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