ZINC PYITHIONE

It is a formulation of zinc, it is the most commonly used substance in the treatment of intense dandruff, it may be sufficient alone, but it is known that its effectiveness is increased with climbazol in cases where dandruff is too exaggerated such as excessive dandruff, oily eczema and psoriasis.

Zink pyrition solves the problem by dissolving the dead skin layer that develops due to rapid skin regeneration, which is the cause of dandruff, and this effect is called keratolytic effect. Since the main problem in seborrheic dermatitis and excessive dandruff is fungus, the use of climbazole in addition will increase the success in treatment.

The only use of Zink Pyrition is shampoos, it can be used in shampoos with different structures, it can be used in shampoos that cannot be used more than 2 times a week, as well as in high quality shampoos suitable for daily use.

There are many scientific studies done with Zink pyrition + climbazol, and better results have been obtained than zink pyrition alone. If you have oily eczema or excessive dandruff, your choice should be a shampoo with zink pyrition and climbazol.

It is a chemical among the pyrithione complex compounds of Zinc Bromide. It is a chemical with antifungal and antimicrobial properties.

How is it produced?
Zinc Pyrithione production A compound consisting of a 2-Bromopyridine N-oxide or a 2-chloropyridine group is selected. One of the bases of Sodium Hydrosulfite, sodium carbonate and sodium hydroxide is added to this selected aqueous solution. During the base addition process, the temperature ranges between 20 ° C and 65 ° C.

The sodium pyrithione obtained in the production process is increased from 75 ° C to 105 ° C and reacted with a zinc salt. The zinc salt used here is zinc chloride (ZnCl2) or zinc sulphate (ZnSO4).

What Are Its Physical And Chemical Properties?
It is in cloudy white powder form.

Melting Point is approximately 240 ° C.

Its density at 25 ° C is 1.782 g / cm³.

It emits toxic fumes when heated with heat. These emit nitrogen oxides, zinc oxide and sulfur oxide fumes.

It has low resolution. Polyethylene Glycol (PEG400) has a resolution of 2g / kg.

The pH range is between 4.5 and 9.5.

What Are The Uses Of Zinc Pyrithione?
It is an antifungal and antimicrobial agent that blocks the transport of membranes.
It is the chemical zinc pyrithione that prevents the formation of mold caused by gram positive and gram negative bacteria on the hair.
In the cosmetics industry, it is used in the production of hair strengthening and rejuvenating shampoos that prevent hair whitening.
It is used to prevent bacterial growth in the paint.
It is used to destroy such fungi in order to prevent the formation of dandruff fungi on hair. It also has low irritating properties.
It prevents the growth of fungi by interfering with the primary proton pump.
Blackmail is an important ingredient for regulating the structure of keratin. It is processed using a range of 1% - 2%.
It prevents the formation of bacteria and algae in outdoor paints.

[Molecular Formula]

C10H8N2O2S2Zn
[MDL Number]

MFCD00067336
[Molecular Weight]

317.7
[MOL File]

13463-41-7.mol
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[Chemical Properties]

Beige granules
[General Description]

Fine beige granules.
[Reactivity Profile]

Organometallics, such as ZINC PYRITHIONE(13463-41-7), are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases.
[Air & Water Reactions]

Insoluble in water.
[Fire Hazard]

Flash point data for this chemical are not available, but ZINC PYRITHIONE is probably combustible.
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[Water Solubility ]

Insoluble (<0.1 g/100 mL at 21 ºC)

[Contact allergens]

Zinc pyrithione is widely used in antidandruff shampoos and is a classic allergen. Concomitant reactions are expected to both zinc and sodium pyrithione.

[Uses]

zinc pyrithione is a preservative against bacteria, fungi, and yeast. It is unstable in light and in the presence of oxidizing agents. Zinc pyrithione is useful in gels, creams, heavy lotions, and talcum powder.

[Product description ]

Zinc pyrithione is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent. At room temperature it is white to yellow crystalline powder. Slight characteristic odor. Insoluble in water. Solubility: water 15mg/kg; pH = 8 Water 35mg/kg; Ethanol 100mg/kg; polyethylene glycol (PEG400) 2000mg/kg. A pH optimum range of 4.5 to 9.5; mass fraction of 10% suspension pH3.6. Zinc pyrithione react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures ,it is not stable to acids and bases . It is not compatible with EDTA, non-ionic surfactants make it partially deactivated. When with the presence of heavy metals, chelation or anti-sequestration will occur, and these chelates are insoluble in water.
EEC and GB7916-87 provide that maximum allowable concentration of mass fraction of zinc pyrithione on cosmetics is 0.5%, only for cleaning after using products.General concentration 250~1000mg/kg (active), zinc pyrithione can be used in gels, creams, lotions, talcum powder and anti-dandruff shampoo, deodorant and also for disinfecting articles.

[Uses]

Shampoo for dandruff,zinc pyrithione can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation. zinc pyrithion is also used as a cosmetic preservative, oil, paint biocide.
Zinc pyrithione has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .