ZINC PYRITHIONE 48 %

Zinc Pyrithione 48% is a concentrated Zinc Pyrithione dispersion or slurry designed to deliver antifungal and antimicrobial performance in formulated products at controlled dosing levels.
Zinc Pyrithione 48% is widely used as an active ingredient for anti-dandruff and scalp care products and as an industrial biocide in compatible coatings, plastics, and specialty applications where regulations allow.
Zinc Pyrithione 48% performance depends strongly on dispersion quality, particle size distribution, pH, and compatibility with surfactants, polymers, and chelating agents, so Zinc Pyrithione 48% must be incorporated with appropriate mixing and stability control.

CAS Number: 13463-41-7 (Zinc Pyrithione active)
EC Number: 236-671-3
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 317.70 g/mol

Synonyms: Zinc Pyrithione 48%, ZnPT 48%, ZPT 48%, Zinc Omadine 48% (common naming), Zinc Pyrithione Dispersion 48%, Zinc Pyrithione Slurry 48%, Zinc Pyrithione Concentrate 48%, Zinc Pyrithione Active Dispersion, Antidandruff Active 48% ZPT, Zinc Pyrithione 48% Suspension, Zinc Pyrithione 48% Aqueous Dispersion, Zinc Pyrithione Biocide 48%, Zinc Pyrithione 48%, ZINC PYRITHIONE 48%, Zinc pyrithione 48%, ZPT 48%, ZPT (Zinc Pyrithione) 48%, Zinc Pyrithione 48% dispersion, Zinc Pyrithione 48% slurry, Zinc Pyrithione 48% aqueous dispersion, Zinc Pyrithione 48% suspension, Zinc Pyrithione 48% concentrate, Zinc Pyrithione 48% active, Zinc Pyrithione 48% active content, Zinc Pyrithione 48% w/w, Zinc Pyrithione 48% (w/w) dispersion, Zinc Pyrithione 48% (w/w) slurry, Zinc Pyrithione 48% (INCI), Zinc Pyrithione 48% (anti-dandruff), Zinc Pyrithione 48% anti-dandruff active, Anti-dandruff active ZPT 48%, Zinc Pyrithione 48% shampoo grade, Zinc Pyrithione 48% personal care grade, Zinc Pyrithione 48% cosmetic grade, Zinc Pyrithione 48% wettable dispersion, Zinc Pyrithione 48% water-based dispersion, Zinc Pyrithione 48% stabilized dispersion, Zinc Pyrithione 48% preservative (use context), Zinc Pyrithione 48% biocide, Zinc Pyrithione 48% microbicide, Zinc Pyrithione 48% antifungal, Zinc Pyrithione 48% antimicrobial, Zinc Pyrithione 48% anti-yeast, Zinc Pyrithione 48% anti-Malassezia, Zinc Pyrithione 48% scalp treatment active, Zinc Pyrithione 48% shampoo active, Zinc Pyrithione 48% suspension concentrate (common wording), Zinc Pyrithione 48% ready-to-use dispersion

APPLICATIONS

Zinc Pyrithione 48% is used in anti-dandruff shampoos to control dandruff-associated fungi and reduce visible flaking.
Zinc Pyrithione 48% is incorporated into rinse-off shampoos to provide uniform dosing and consistent dispersion compared with handling dry powder.
Zinc Pyrithione 48% is used in 2-in-1 shampoo and conditioner systems where deposition and conditioning are engineered for efficacy.

Zinc Pyrithione 48% is used in scalp scrubs and scalp masks to support dandruff control routines in rinse-off formats.
Zinc Pyrithione 48% is incorporated into scalp tonics and leave-on products only where regulations and safety assessments permit.
Zinc Pyrithione 48% is used in dandruff-targeted cleansing bars to deliver antifungal activity with controlled processing.

Zinc Pyrithione 48% is used in body washes and soaps in some markets to support antimicrobial cleansing in rinse-off applications where permitted.
Zinc Pyrithione 48% is incorporated into foot care washes to support reduction of odor-causing microbes and fungal pressure in compatible systems.
Zinc Pyrithione 48% is used in intimate hygiene cleansing products only when compliant with local cosmetic and biocide regulations.

Zinc Pyrithione 48% is used in paints and coatings as a biocide to control microbial growth and film mildew in compatible industrial systems.
Zinc Pyrithione 48% is incorporated into exterior coatings to reduce fungal growth and protect film integrity in humid environments.
Zinc Pyrithione 48% is used in marine and protective coatings as part of biocide packages designed for long-term performance.

Zinc Pyrithione 48% is used in plastics and polymer materials to provide antimicrobial protection in selected applications where additive incorporation is validated.
Zinc Pyrithione 48% is incorporated into PVC and elastomers to reduce odor and microbial growth on product surfaces in compatible designs.
Zinc Pyrithione 48% is used in polymer masterbatches where controlled dispersion improves distribution in the final part.

Zinc Pyrithione 48% is used in textiles to provide antimicrobial and anti-odor finishing in compatible treatments.
Zinc Pyrithione 48% is incorporated into textile coatings and finishes to reduce microbial growth and odor formation.
Zinc Pyrithione 48% is used in textile applications only when regulatory requirements and wash durability performance are validated.

Zinc Pyrithione 48% is used in formulated biocide products where dosing, exposure, and disposal are managed under regulations.
Zinc Pyrithione 48% is incorporated into process protection strategies to reduce microbial contamination in susceptible systems where permitted.
Zinc Pyrithione 48% is used in industrial maintenance coatings and construction products as a microbial control additive in compatible formulations.

Zinc Pyrithione 48% is valued because Zinc Pyrithione 48% provides a high-active, easy-to-dose dispersion format that simplifies manufacturing and supports consistent antimicrobial performance when compatibility, particle size, and regulatory limits are respected.

Zinc Pyrithione 48% is used as a pre-dispersed anti-dandruff active for shampoo manufacturing.
Zinc Pyrithione 48% supports easier dosing and uniform distribution compared with adding dry powder.
Zinc Pyrithione 48% helps improve batch consistency by delivering controlled active concentration.

Zinc Pyrithione 48% is used in anti-dandruff shampoos to control Malassezia-associated dandruff.
Zinc Pyrithione 48% helps reduce visible flaking and scalp scaling with regular use.
Zinc Pyrithione 48% supports improved scalp comfort by reducing itch associated with dandruff.

Zinc Pyrithione 48% is used in 2-in-1 anti-dandruff shampoo and conditioner products.
Zinc Pyrithione 48% supports deposition of the active while maintaining conditioning performance.
Zinc Pyrithione 48% helps deliver dandruff control without overly harsh cleansing.

Zinc Pyrithione 48% is used in professional anti-dandruff cleansers for consistent performance.
Zinc Pyrithione 48% supports stable active delivery across different shampoo bases.
Zinc Pyrithione 48% helps maintain consistent efficacy when viscosity and surfactant systems vary.

Zinc Pyrithione 48% is used in anti-seborrheic dermatitis rinse-off scalp treatments in regulated product categories.
Zinc Pyrithione 48% supports control of yeast overgrowth linked to scalp scaling in compliant systems.
Zinc Pyrithione 48% helps improve scalp hygiene performance when used according to label and regulations.

Zinc Pyrithione 48% is used in medicated body washes for yeast-prone skin areas in regulated formats where permitted.
Zinc Pyrithione 48% supports microbial control on skin surface in rinse-off cleansing.
Zinc Pyrithione 48% helps reduce odor and discomfort linked to microbial overgrowth in compliant products.

Zinc Pyrithione 48% is used in bar soaps and syndet bars in some markets where antimicrobial additives are permitted.
Zinc Pyrithione 48% supports microbial control in rinse-off cleansing formats.
Zinc Pyrithione 48% helps reduce odor-causing microbial growth when used within allowed limits.

Zinc Pyrithione 48% is used in deodorant concepts only where local regulations allow zinc pyrithione use.
Zinc Pyrithione 48% supports odor control by reducing microbial activity that produces malodor.
Zinc Pyrithione 48% helps extend freshness perception in compliant deodorant systems.

Zinc Pyrithione 48% is used as a ready-to-handle dispersion for faster manufacturing and reduced dust exposure.
Zinc Pyrithione 48% supports safer handling by avoiding powder dusting during charging.
Zinc Pyrithione 48% helps reduce inhalation risk in manufacturing environments with appropriate controls.

Zinc Pyrithione 48% is used to improve particle dispersion quality in shampoo bases.
Zinc Pyrithione 48% supports stable suspension and reduced settling when combined with suitable thickeners.
Zinc Pyrithione 48% helps maintain uniform active distribution in finished products on shelf.

Zinc Pyrithione 48% is used in pearlescent anti-dandruff shampoos to maintain stable appearance with suspended solids.
Zinc Pyrithione 48% supports stable visual quality by providing uniform particle distribution.
Zinc Pyrithione 48% helps reduce sedimentation defects in clear or pearly systems through controlled rheology.

Zinc Pyrithione 48% is used in shampoo formulations where controlled particle size supports better deposition onto scalp.
Zinc Pyrithione 48% supports consistent deposition and improved performance in rinse-off applications.
Zinc Pyrithione 48% helps improve repeatability of efficacy by controlling dispersion parameters.

Zinc Pyrithione 48% is used in product development to optimize active delivery without reformulating around raw powder.
Zinc Pyrithione 48% supports rapid prototyping of multiple shampoo bases.
Zinc Pyrithione 48% helps shorten development time by simplifying active incorporation.

Zinc Pyrithione 48% is used in stability studies to evaluate active suspension behavior under temperature cycling.
Zinc Pyrithione 48% supports accelerated testing of settling, caking, and redispersibility.
Zinc Pyrithione 48% helps define appropriate thickener and suspending agent systems.

Zinc Pyrithione 48% is used in paints and coatings as a mildewcide and dry-film preservative where permitted by regulation.
Zinc Pyrithione 48% supports longer coating life in humid environments by preventing mold and mildew growth.
Zinc Pyrithione 48% helps reduce discoloration and coating degradation caused by fungal growth.

Zinc Pyrithione 48% is used in interior architectural coatings to protect the dried film from microbial growth.
Zinc Pyrithione 48% supports improved appearance retention in damp rooms such as bathrooms.
Zinc Pyrithione 48% helps reduce mildew spotting and staining on paint films.

Zinc Pyrithione 48% is used in exterior coatings to reduce algae and fungal growth in some systems where permitted.
Zinc Pyrithione 48% supports reduced green growth and mildew on facades.
Zinc Pyrithione 48% helps improve maintenance intervals by limiting biological fouling.

Zinc Pyrithione 48% is used in R&D to compare different dispersion carriers and particle sizes for deposition efficiency.
Zinc Pyrithione 48% supports optimization of deposition and rinse-off performance.
Zinc Pyrithione 48% helps improve efficacy while managing sensory feel and appearance.

Zinc Pyrithione 48% is used in preservative system design for coatings to achieve stable in-can and dry-film protection.
Zinc Pyrithione 48% supports improved microbial robustness of paint systems during storage.
Zinc Pyrithione 48% helps protect dried films from mildew growth in humid exposure.

Zinc Pyrithione 48% is used in training and education for cosmetic and coatings formulation as an example of an insoluble biocidal active delivered by dispersion.
Zinc Pyrithione 48% supports teaching about particle suspension, deposition, and regulatory limits.
Zinc Pyrithione 48% helps illustrate the importance of dispersion quality for performance.

Zinc Pyrithione 48% is used in pilot-scale manufacturing to reduce dusting and improve batch turnaround versus powder handling.
Zinc Pyrithione 48% supports easier charging and faster dispersion under agitation.
Zinc Pyrithione 48% helps improve manufacturing safety and reproducibility.

DESCRIPTION

Zinc Pyrithione 48% is a dispersion containing approximately 48% active Zinc Pyrithione, and the remaining fraction is typically water and/or compatible carriers plus dispersants and stabilizers depending on supplier design.
Zinc Pyrithione 48% is used instead of dry powder to reduce dust exposure, improve manufacturing safety, and enable easier incorporation into surfactant and coating systems.
Zinc Pyrithione 48% is poorly soluble in water, so Zinc Pyrithione 48% functions as suspended particles, and stable suspension requires controlled particle size and appropriate rheology.

Zinc Pyrithione 48% can be deactivated by strong chelating agents and can be sensitive to some formulation conditions, so compatibility with EDTA-like chelants, sulfide sources, and extreme pH should be evaluated.
Zinc Pyrithione 48% stability depends on maintaining proper dispersion, and settling can occur if viscosity and particle size are not controlled, so mixing and storage procedures matter.
Zinc Pyrithione 48% is subject to regulatory restrictions in some regions and product categories, and permitted concentration limits and product types can vary by market and time.

Zinc Pyrithione 48% should be stored in tightly closed containers and protected from freezing and excessive heat to maintain dispersion quality.
Zinc Pyrithione 48% should be protected from contamination and from strong acids or strong bases that could destabilize the dispersion.
Zinc Pyrithione 48% should be handled only by trained personnel and used according to supplier specifications, safety documentation, and applicable regulations.

Zinc Pyrithione 48% is a concentrated dispersion or slurry containing approximately 48% active zinc pyrithione in a carrier system.
Zinc Pyrithione 48% is used to simplify handling and dosing of zinc pyrithione into formulations.
Zinc Pyrithione 48% is typically supplied as an off-white to pale slurry with controlled particle size distribution.

Zinc Pyrithione 48% contains insoluble zinc pyrithione particles that must remain well suspended for consistent dosing.
Zinc Pyrithione 48% performance depends on dispersion stability, viscosity, and redispersibility after storage.
Zinc Pyrithione 48% is usually incorporated under controlled mixing to avoid foam and ensure uniform distribution.

PROPERTIES

Active Ingredient: Zinc Pyrithione
Active Content: ~48% (w/w) (supplier specification dependent)
Chemical Formula (active): C10H8N2O2S2Zn
Molecular Weight (active): 317.70 g/mol
Common Name: Zinc Pyrithione 48% (ZPT 48%, ZnPT 48%)
Chemical Type: Antifungal and antimicrobial active (particulate dispersion)
Appearance: White to off-white slurry or dispersion (grade dependent)
Odor: Slight characteristic odor (grade dependent)
Solubility: Very low solubility in water; delivered as a suspension
Particle Size: Grade dependent; strongly influences stability and efficacy
pH Range: Typically near neutral to slightly acidic depending on carrier system (grade dependent)
Stability: Sensitive to chelants and some formulation conditions; protect from freezing and contamination
Storage Temperature: 5–25°C, tightly closed; protect from freezing and excessive heat
Shelf Life: Typically 12–24 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if mists or aerosols are inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing aerosols during mixing and transfer.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water and seek medical attention promptly.
Do not induce vomiting unless directed by medical personnel.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses, and avoid splashing into eyes.
Avoid generating aerosols and avoid inhalation of mists during transfer and mixing.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use general ventilation for normal handling.
Use local exhaust if mists may be generated during high-shear mixing.
Avoid aerosol formation in enclosed spaces without proper ventilation.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from freezing and excessive heat to maintain dispersion stability and prevent settling or phase separation.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Contain spills and absorb with inert material.
Clean surfaces thoroughly because wet dispersions can create slip hazards.
Dispose of waste according to local regulations and facility procedures.

Handling Precautions:
Use Zinc Pyrithione 48% in accordance with local cosmetic and biocide regulations and confirm permitted product types and maximum concentration.
Maintain dispersion quality by mixing gently before use and avoiding extreme shear that can introduce air or destabilize rheology.
Avoid strong chelants and incompatible formulation conditions that can reduce activity, and verify stability and efficacy with testing.