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ZINC PYRITHIONE (ANTIDANDRUFF)

Zinc Pyrithione (Antidandruff) is a coordination complex of zinc. 
Zinc Pyrithione (Antidandruff) has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.

CAS no.: 13463-41-7
EC Number: 236-671-3
IUPAC name: bis(2-pyridylthio)zinc 1,1'-dioxide
Chemical formula: C10H8N2O2S2Zn

Other names: Zinc pyridinethione, ZnPT, Pyrithione zinc derivative, 1-Hydroxypyridine-2-thione zinc salt, 2-Mercaptopyridine N-Oxide Zinc Salt, zinc;1-oxidopyridine-2-thione, NSC-290409, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4)-, zinc 1-oxidopyridine-2-thione, Zinc - pyrion, Zn - pyrion, SCHEMBL136623, zinc 1-oxido-2-pyridinethione, GTPL2597, CHEMBL1200471, CHEMBL3392049, OTPSWLRZXRHDNX-UHFFFAOYSA-L, zinc 1-oxidanidylpyridine-2-thione, zinc 1-oxidopyridin-1-ium-2-thiol, AKOS015891514, AKOS015951268, Bis(2-pyridylthio) Zinc 1,1'-Dioxide, NCGC00091933-02, AC-13775, FT-0636895, M0633, {Bis[1-hydroxy-2(1H)-pyridinethionato]zinc}, D01938, A806815, ZINC(2+) BIS(2-SULFANYLIDENEPYRIDIN-1-OLATE), zinc(2+) bis(6-sulfanylidene-3H-pyridin-1-ium-3-id-1-olate)

Structure of the compound
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. 
In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.

This compound was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.

Uses:
Medicine
Zinc Pyrithione (Antidandruff) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (Antidandruff) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.

Paint
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (Antidandruff) is suitable for use in outdoor paints and other products that protect against mildew and algae. 
Zinc Pyrithione (Antidandruff) is an algaecide. 
Zinc Pyrithione (Antidandruff) is chemically incompatible with paints relying on metal carboxylate curing agents. 
When Zinc Pyrithione (Antidandruff)is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed. 
Zinc Pyrithione (Antidandruff)is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges
Zinc Pyrithione (Antidandruff) is an antibacterial treatment for household sponges, as by the 3M Corporation.

Clothing
A process to apply Zinc Pyrithione (Antidandruff) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (Antidandruff) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (Antidandruff) protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015.

Mechanism of action
Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism

What is pyrithione zinc?
Pyrithione zinc, also commonly known as Zinc Pyrithione (Antidandruff), has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.

Zinc Pyrithione (Antidandruff) can inhibit the growth of yeast, which is a main factor in dandruff. 
As the name suggests, pyrithione zinc is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.

Zinc Pyrithione (Antidandruff) shampoo
Zinc Pyrithione (Antidandruff) shampoo is found in many common anti-dandruff shampoos. 
Zinc Pyrithione (Antidandruff) is antifungal, antibacterial, and antimicrobial, meaning Zinc Pyrithione (Antidandruff) can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.

To use, follow the instructions on the bottle, but generally you should:
Apply to wet scalp.
Work into a lather.
Let Zinc Pyrithione (Antidandruff) sZinc Pyrithione (Antidandruff) on your scalp for a minute.
Rinse thoroughly.

Zinc Pyrithione (Antidandruff) cream
Seborrheic dermatitis often affects the scalp, but Zinc Pyrithione (Antidandruff) can also cause rough, scaly patches on the skin. 
Zinc Pyrithione (Antidandruff) cream is used to treat seborrheic dermatitis or psoriasis on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione (Antidandruff) followed by a moisturizer. 
You can also use the cream daily by applying Zinc Pyrithione (Antidandruff) in a thin layer to the affected area.

Zinc Pyrithione (Antidandruff) face wash
Zinc Pyrithione (Antidandruff) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face. 
Zinc Pyrithione (Antidandruff) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione (Antidandruff) may help clear acne.

Pyrithione zinc vs. selenium sulfide
Selenium sulfide is a topical antifungal treatment that slows the growth of yeast on the scalp or body.
It’s available in both prescription and OTC forms.

Like pyrithione zinc, it’s also commonly found in anti-dandruff shampoos, and the two ingredients can complement each other. 
Selenium sulfide is known to be a bZinc Pyrithione (Antidandruff) stronger and can be irritating if left on the scalp for too long. 
It’s naturally a light orange color, so shampoos or skin care products containing selenium sulfide are usually a peachy hue.

Takeaway
Pyrithione zinc, which is also known as Zinc Pyrithione (Antidandruff), is a common ingredient in anti-dandruff shampoos, but it can also be effective at treating psoriasis, eczema, and acne.
This is because of its antimicrobial, antibacterial, and antifungal properties.

It’s meant for topical use only, and may cause burning or stinging if it comes into contact with your eyes, nose, or mouth.
Zinc Pyrithione (Antidandruff) should never be ingested. 
If you’re pregnant, nursing, or thinking of using a product that contains pyrithione zinc on a child, speak with a doctor before doing so.

Product description    
Zinc Pyrithione (Antidandruff) is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent. 
At room temperature it is white to yellow crystalline powder. Slight characteristic odor. 
Insoluble in water. 

A pH optimum range of 4.5 to 9.5; mass fraction of 10% suspension pH3.6. 
Zinc Pyrithione (Antidandruff) react with cationic and non-ionic surfactants forming insoluble precipitate, unstable in the light and oxidizer, when at higher temperatures ,it is not stable to acids and bases. 
Zinc Pyrithione (Antidandruff) is not compatible with EDTA, non-ionic surfactants make it partially deactivated.
When with the presence of heavy metals, chelation or anti-sequestration will occur, and these chelates are insoluble in water.

EEC and GB7916-87 provide that maximum allowable concentration of mass fraction of Zinc Pyrithione (Antidandruff) on cosmetics is 0.5%, only for cleaning after using products.General concentration 250~1000mg/kg (active), Zinc Pyrithione (Antidandruff) can be used in gels, creams, lotions, talcum powder and anti-dandruff shampoo, deodorant and also for disinfecting articles.

Uses:    
Shampoo for dandruff,Zinc Pyrithione (Antidandruff) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation. 
zinc pyrithion is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (Antidandruff) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff.

Zinc Pyrithione (Antidandruff) is directly cytotoxic and has antimicrobial effects. 
Zinc Pyrithione (Antidandruff) is found in many shampoos (DHS-Zinc, Head and Shoulders) and should be applied for 5 minutes daily for 2 weeks.
Zinc Pyrithione (Antidandruff) is the active ingredient in several shampoos used to control dandruff and seborrheic dermatitis and is also effective in the therapy of tinea versicolor.

Zinc Pyrithione (Antidandruff) remains unclear whether the beneficial effects are caused by an antiproliferative or antimicrobial effect or both. 
Zinc Pyrithione (Antidandruff) is substantive to the hair, allowing continued therapeutic effect after washing.
Zinc Pyrithione (Antidandruff) is a preservative against bacteria, fungi, and yeast. 
Zinc Pyrithione (Antidandruff) is unstable in light and in the presence of oxidizing agents. 

Zinc Pyrithione (Antidandruff) is useful in gels, creams, heavy lotions, and talcum powder.
Reactions may lead to photosensitive eczema and actinic reticuloid syndrome. 
Zinc Pyrithione (Antidandruff) is used as antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.

Indications    
Zinc Pyrithione (Antidandruff) is the active ingredient in several shampoos used to control dandruff and seborrheic dermatitis and is also effective in the therapy of tinea versicolor. 
Zinc Pyrithione (Antidandruff) remains unclear whether the beneficial effects are caused by an antiproliferative or antimicrobial effect or both. 
Zinc Pyrithione (Antidandruff) is substantive to the hair, allowing continued therapeutic effect after washing.

Pharmaceutical Applications    
Zinc Pyrithione (Antidandruff) is a regulator of keratinization, selenium sulfide has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).

Efficacy    
Zinc Pyrithione (Antidandruff) shampoos (in concentrations between 1 to 2%) and shampoos with selenium sulide have been reported to be effective in the treatment of scalp psoriasis.
However,their efficacy has not been substantiated by controlled studies.
There is also some evidence that shampoos with antifungal agents (e.g.ketoconazole)can have a beneficial effect on scalp conditions. 
Zinc Pyrithione (Antidandruff) should be noted, however, that the effectiveness of these shampoos is much smaller than these containing tars, corticosteroids or keratolytics.

Photolysis    
Zinc Pyrithione (Antidandruff) is very rapidly transformed by photolysis. 
Experiments conducted under sterile conditions with a light:dark cycle of 12:12 hours have shown that, under exposure to light, the concentration of [pyridine-2,6-14C]Zinc Pyrithione (Antidandruff) in pH 9 buffer was reduced to 33% of the radioactivity added in 15 min.

Data from this study also demonstrated that less than 5% of the 14C added occurred as Zinc Pyrithione (Antidandruff) after 1 hour of exposure to light. 
Similar results have been achieved when photolysis of Zinc Pyrithione (Antidandruff) was investigated by use of artificial seawater.

In this study, the parent compound constituted 45% of the radioactivity added after 15 min while, after 24 hours, 1.3% of the added dose occurred as Zinc Pyrithione (Antidandruff). 
The estimated half-lives of the photolytic transformation of Zinc Pyrithione (Antidandruff) was 13 min in pH 9 buffer and 17.5 min in artificial seawater (Reynolds 1995a).

Use and Manufacturing
Household & Commercial/Institutional Products
Home Maintenance
Personal Care

Uses of Pyrithione Zinc Shampoo:
Zinc Pyrithione (Antidandruff) is used to control seborrheic dermatitis.
Zinc Pyrithione (Antidandruff) is used to treat skin irritation and dandruff.
Zinc Pyrithione (Antidandruff) may be given to you for other reasons. Talk with the doctor.

Appearance: colourless solid
Melting point: 240 °C
Boiling point: decomposes
Solubility in water: 8 ppm

Molecular Weight: 317.7 g/mol
Hydrogen Bond Acceptor Count: 4
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 117Ų

Heavy Atom Count: 17
Complexity: 162
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Zinc Pyrithione (Antidandruff) is the most used active in anti-dandruff shampoos.
Zinc Pyrithione (Antidandruff) works by killing both local fungi and bacteria on the scalp. 
It’s cheap, efficient and has a variety of uses outside of haircare: you find it in kitchen sponges so that they don’t grow mouldy for example.

Pyrithione zinc, or Zinc Pyrithione (Antidandruff) or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. 
In the crystalline state, it exists as a centrosymmetric dimer. 
Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat dandruff and seborrheic dermatitis. 
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta.

Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. 
Zinc Pyrithione (Antidandruff) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth. 
Due to low solubility, pyrithione zinc released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.

Other uses of pyrithione zinc include additive in antifouling outdoor paints and algaecide. 
While its use has been approved in the early 1960's by the FDA, safety and effectiveness of pyrithione zinc has been reported for decades. 
Zinc Pyrithione (Antidandruff) is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays.

What is Zinc Pyrithione (Antidandruff)?
Zinc Pyrithione (Antidandruff) is a coordination complex of zinc and pyrithione that is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.

Zinc Pyrithione (Antidandruff) is the zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione. Pyrithione was first synthesized by E. Shaw and co-workers in 1950. 
The preparation of the zinc derivative was disclosed by Olin Mathieson in a 1956 British patent, but the compound has been used since the 1930s.

Zinc Pyrithione (Antidandruff) was originally used as an antibacterial and antifungal agent. 
Zinc Pyrithione (Antidandruff) is still used as an antifungal, primarily as a treatment for dandruff and seborrheic dermatitis. 
Its current antibacterial uses are treating Streptococcus and Staphylococcus infections and psoriasis, eczema, ringworm, and athlete’s foot. 
Its primary nonmedical use is as a component in exterior paints to protect against mildew and algae.

General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. 
Zinc Pyrithione (Antidandruff) is used for controlling a variety of fungal infections. 
Zinc Pyrithione (Antidandruff) is used commercially in personal care products, including antidandruff shampoos and skin creams.

Uses:
These Secondary Standards are qualified as Certified Reference Materials. 
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Zinc Pyrithione (Antidandruff) is considered as a coordination complex of zinc. 
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers. 
In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers. 
In solution, however, the dimers dissociate via scission of one Zn-O bond.

Zinc Pyrithione (Antidandruff), which is a dimer but is probably biologically active as a monomer, induces plasma membrane depolarization with half-maximal effect (K1/2) of about 0.3 mM.
Zinc Pyrithione (Antidandruff) is an unusual synthetic potentiator that potently activates both heterologous and native M channels by inducing channel opening at the resting potential. 

Zinc Pyrithione (Antidandruff) rapidly accumulated in the tissues of the exposed mussels, proportionately to both exposure concentration and time. 
Even though the 7-d median lethal concentration (LC50) = 8.27 μM established here appears high with respect to reported ZnPT environmental concentrations, the results indicate that this biocide could represent a threat for marine organisms in coastal environments and that further investigations on its biological effects at sublethal doses are needed.

Zinc Pyrithione (Antidandruff) is an antibacterial and antifungal that is found mainly in anti-dandruff shampoos. 
Zinc Pyrithione (Antidandruff) is particularly adapted to fight against Malessezia, a fungus naturally present on the skin, but responsible for dandruff of the scalp.

What Is Zinc Pyrithione (Antidandruff)?
Zinc Pyrithione (Antidandruff) is one of several zinc preparations formulated for human use and consumption. 
Zinc Pyrithione (Antidandruff) in particular is a topical agent — and when used on the skin, can treat skin conditions such as acne, warts, dandruff and rosacea. 
Zinc Pyrithione (Antidandruff) can even be used in the treatment of diseases like leprosy, basal cell carcinoma and genital herpes.

Zinc Pyrithione (Antidandruff) can also treat psoriasis, eczema, ulcers, certain forms of alopecia and vitiligo, and can generally help as an anti-aging skincare ingredient.
Because of its antifungal properties, this form of zinc is often used as a treatment for dandruff. It’s a common ingredient in anti-dandruff shampoos. 

How Does This Relate to Acne?
Your skin’s normal process of shedding dead skin cells from the inside of your hair follicles is important, and when it breaks down, you can get acne. 

Problems with the shedding process can result in a particular bacterial infection if those excess dead cells and the oils produced clog the pore. 
A mixture of sebum or oil and your dead cells is the perfect breeding ground and food source for bacteria — which is the bacteria that causes acne.

Plenty of things can trigger a skin process imbalance, whether it’s poor diet and dehydration, a dry climate’s toll on your skin or hormone imbalances. 
The hormones usually in this group are called androgens. 

Androgens can significantly increase your oil production through the sebaceous glands, making them instrumental to the development of acne. 
Sebum is generally good and can help protect your skin. Yet when it starts to block pores, it can help provide more of a breeding ground for bacteria. 

Zinc Pyrithione (Antidandruff) and Acne
So where does Zinc Pyrithione (Antidandruff) come in?

How Zinc Pyrithione (Antidandruff) actually works for acne isn’t fully understood, according to recent studies. 
The current thinking is that it has some impact on both inflammatory issues due to microbes, as well as on antibiotic absorption.
Zinc Pyrithione (Antidandruff) has also demonstrated the ability to inhibit the growth and productivity of the P. acnes bacteria.

Zinc Pyrithione (Antidandruff) has also been shown to have antifungal activity, so in those rare fungal acne cases, it has demonstrated benefits.
Furthermore, Zinc Pyrithione (Antidandruff) has been shown to work in combination with antibiotic treatments. 

Research has shown how promising zinc treatments are — not just because of their effectiveness and ability to work in combination with other treatments, but also because they are low cost and lack systemic side effects.

Is any of this a cure for acne? Not exactly, but it’s another tool with a steadily growing body of knowledge. 
Zinc Pyrithione (Antidandruff) and Ketoconazole
The efficacy of Zinc Pyrithione (Antidandruff) when used in combination with other medications is actually well demonstrated through another of zinc’s uses: dandruff treatments. 

Ketoconazole shampoo can be an effective treatment for seborrheic dermatitis, and in multiple studies has been shown to be a superior treatment when compared to similar options.
Like other topical medications (especially the ones that go on your head) it’s best to try just a small amount first (in one location) when you begin using it. 

Once you’ve confirmed that no serious or immediate reactions are taking place, you can apply the shampoo like normal. Just be sure to follow the directions on the label for best results.
Ketoconazole shampoo may cause some side effects, according to the U.S. National Library of Medicine. 
These may include blisters on the scalp, changes in hair texture, dry skin, itching, oily or dry hair or scalp, irritation or stinging.

If these symptoms persist or worsen, call your healthcare provider. Call them immediately if you see signs of rash or hives, or if you have difficulty breathing or pain.
Used in combination with Zinc Pyrithione (Antidandruff), ketoconazole is effective at disrupting fungal membranes — which can eventually help you fight them off for good.

Zinc works well with ketoconazole, which (as mentioned above) is an antifungal medication commonly used in shampoo to treat seborrheic dermatitis — a condition that causes skin irritation and flaking, and which can lead to dandruff when it affects the scalp. 

Zinc Pyrithione (Antidandruff) and Your Skin
Zinc Pyrithione (Antidandruff) may be another effective tool to fight acne and dandruff yet if you experience either of these conditions, know you have options. 

The best place to start is by connecting with a healthcare professional, to help determine what might be causing your issue, and to help find the best treatment for you. 
Either way, Zinc Pyrithione (Antidandruff) is a proven ingredient that can help clear up your skin and scalp.

Zinc Pyrithione (Antidandruff) is an antibacterial and antifungal compound C10H8N2O2S2Zn that is nearly insoluble in water, possesses cytostatic activity against epidermal cells, and is the active ingredient in various shampoos used to control dandruff and seborrheic dermatitis

Zinc Pyrithione (Antidandruff) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump. Target: Proton Pump Zinc Pyrithione (Antidandruff) is considered as a coordination complex of zinc. 
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers. 
In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via scission of one Zn-O bond. 
Zinc Pyrithione (Antidandruff), which is a dimer but is probably biologically active as a monomer, induces plasma membrane depolarization with half-maximal effect (K1/2) of about 0.3 mM. 
Zinc Pyrithione (Antidandruff) is an unusual synthetic potentiator that potently activates both heterologous and native M channels by inducing channel opening at the resting potential.

Zinc Pyrithione (Antidandruff) rapidly accumulated in the tissues of the exposed mussels, proportionately to both exposure concentration and time. 
Even though the 7-d median lethal concentration (LC50) = 8.27 μM established here appears high with respect to reported ZnPT environmental concentrations, the results indicate that this biocide could represent a threat for marine organisms in coastal environments and that further investigations on its biological effects at sublethal doses are needed 

Benefits
Outstanding durability and effectiveness
Broad spectrum of efficacy against bacteria, fungi and dust mites
Long-lasting material protection, e.g., against rotting
High wash resistance

Ease of application in the usual application processes
Readily combined with many textile effects, e.g., fluorocarbons
Can be added to a dye bath

Where is Zinc Pyrithione (Antidandruff) found?
Zinc Pyrithione (Antidandruff) is an antibacterial and antifungal agent. 
It is found in dandruff shampoo and cosmetic products for the treatment of skin problems.


About Zinc Pyrithione (Antidandruff)
Helpful information
Zinc Pyrithione (Antidandruff) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

Zinc Pyrithione (Antidandruff) is used by consumers, by professional workers (widespread uses), in formulation or re-packing and in manufacturing.

Consumer Uses
Zinc Pyrithione (Antidandruff) is used in the following products: cosmetics and personal care products.
Other release to the environment of Zinc Pyrithione (Antidandruff) is likely to occur from: indoor use as processing aid.

Widespread uses by professional workers
Zinc Pyrithione (Antidandruff) is used in the following products: cosmetics and personal care products and laboratory chemicals.
Zinc Pyrithione (Antidandruff) is used in the following areas: scientific research and development and health services.

Zinc Pyrithione (Antidandruff) is used for the manufacture of: chemicals.
Release to the environment of Zinc Pyrithione (Antidandruff) can occur from industrial use: manufacturing of the substance and formulation of mixtures.
Other release to the environment of Zinc Pyrithione (Antidandruff) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Formulation or re-packing
Zinc Pyrithione (Antidandruff) is used in the following products: cosmetics and personal care products and biocides (e.g. disinfectants, pest control products).
Release to the environment of Zinc Pyrithione (Antidandruff) can occur from industrial use: formulation of mixtures.

Manufacture
Release to the environment of Zinc Pyrithione (Antidandruff) can occur from industrial use: manufacturing of the substance.

 
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