ZPT ZINC PYRITHIONE

ZPT Zinc Pyrithione is a zinc coordination compound used as an antimicrobial active, and ZPT Zinc Pyrithione is best known for antifungal performance in anti-dandruff shampoo and scalp care formulations.
ZPT Zinc Pyrithione is valued because ZPT Zinc Pyrithione provides broad activity against Malassezia species associated with dandruff, and ZPT Zinc Pyrithione also shows antimicrobial activity against a range of bacteria and fungi in compatible applications.
ZPT Zinc Pyrithione is typically supplied as a fine powder or as an aqueous dispersion, and ZPT Zinc Pyrithione performance depends on particle size, dispersion quality, pH, and compatibility with surfactants and chelating agents.

CAS Number: 13463-41-7
EC Number: 236-671-3
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 317.70 g/mol

Synonyms: ZPT, Zinc Pyrithione, ZnPT, Zinc Omadine (common name), Zinc 2-Pyridinethiol-1-oxide, Zinc Pyridinethione, Pyrithione Zinc, Zinc Pyrithione Antidandruff, Zinc Pyrithione Antifungal, Zinc Pyrithione Biocide, Zinc Pyrithione Preservative Active, Zinc Pyrithione Powder, ZPT, ZPT (Zinc Pyrithione), Zinc Pyrithione, ZINC PYRITHIONE, Zinc pyrithione, Zinc Pyrithione (ZPT), Pyrithione Zinc, Pyrithione zinc, Zinc Omadine, Zinc omadine, Omadine Zinc, OMADINE ZINC, ZINC OMADINE, Zinc 1-hydroxy-2-pyridinethione, Zinc 1-hydroxy-2-pyridinethione (complex), Zinc 2-pyridinethiol-1-oxide, Zinc 2-pyridinethiol-1-oxide (complex), Zinc 2-pyridinethiol-N-oxide, Zinc 2-pyridinethiol N-oxide, Zinc Pyridine-2-thiol-1-oxide, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc(II), Bis(2-pyridinethiol-1-oxide) zinc, Bis(2-pyridinethiol-1-oxide) zinc(II), Zinc bis(pyrithione), Zinc bis(pyrithione) (ZPT), Zinc Pyrithione (anti-dandruff), Anti-dandruff active (ZPT), Zinc Pyrithione anti-dandruff agent, Zinc Pyrithione antifungal, Zinc Pyrithione antimicrobial, Zinc Pyrithione anti-yeast agent, Zinc Pyrithione anti-Malassezia active, Zinc Pyrithione scalp treatment active, Zinc Pyrithione shampoo active, Zinc Pyrithione preservative (use context), Zinc Pyrithione biocide, Zinc Pyrithione microbicide, Zinc Pyrithione fungicide, Zinc Pyrithione bactericide, Zinc Pyrithione antiseborrheic agent (use context), Zinc Pyrithione (INCI), Zinc Pyrithione cosmetic active, Zinc Pyrithione personal care active, Zinc Pyrithione technical grade, Zinc Pyrithione industrial grade, Zinc Pyrithione cosmetic grade, Zinc Pyrithione high purity, Zinc Pyrithione powder, Zinc Pyrithione fine powder, Zinc Pyrithione dispersion (common supply form), Zinc Pyrithione slurry (common supply form), Zinc Pyrithione 48% (dispersion), Zinc Pyrithione 50% (dispersion),

APPLICATIONS

ZPT Zinc Pyrithione is used in anti-dandruff shampoos to reduce dandruff flaking and relieve scalp itch associated with fungal overgrowth.
ZPT Zinc Pyrithione is incorporated into rinse-off shampoos to provide antifungal activity on the scalp while maintaining cleansing performance.
ZPT Zinc Pyrithione is used in 2-in-1 shampoo and conditioner products where deposition and conditioning are engineered for efficacy.

ZPT Zinc Pyrithione is used in scalp treatments such as rinse-off masks and scalp scrubs to support dandruff control routines.
ZPT Zinc Pyrithione is incorporated into scalp tonics and leave-on products only where regulations and safety assessments permit.
ZPT Zinc Pyrithione is used in scalp care systems with optimized particle size to improve uniform coverage and efficacy.

ZPT Zinc Pyrithione is used in soaps and body washes in some markets to support antimicrobial cleansing in rinse-off applications.
ZPT Zinc Pyrithione is incorporated into shower gels and bar soaps where fungal or odor-control benefits are targeted and permitted.
ZPT Zinc Pyrithione is used in foot care washes to support reduction of odor-causing microbes in compatible systems.

ZPT Zinc Pyrithione is used in deodorant and odor-control products in limited contexts where antimicrobial action is desired and permitted.
ZPT Zinc Pyrithione is incorporated into underarm cleansers to reduce microbial load that contributes to malodor.
ZPT Zinc Pyrithione is used in antimicrobial personal care products only when compliant with local cosmetic and biocide regulations.

ZPT Zinc Pyrithione is used in paints and coatings as a biocide to control microbial growth on film surfaces in compatible industrial systems.
ZPT Zinc Pyrithione is incorporated into marine and exterior coatings to help prevent algae and fungal growth and to protect film integrity.
ZPT Zinc Pyrithione is used in architectural coatings to reduce mildew and biofilm formation in humid environments.

ZPT Zinc Pyrithione is used in plastics to provide antimicrobial protection in selected applications where additive incorporation is validated.
ZPT Zinc Pyrithione is incorporated into polymer materials to reduce odor and microbial growth on product surfaces in compatible designs.
ZPT Zinc Pyrithione is used in PVC and elastomers in niche applications where biocide performance is required.

ZPT Zinc Pyrithione is used in textiles to provide antimicrobial and anti-odor finishing in compatible treatments.
ZPT Zinc Pyrithione is incorporated into textile coatings and finishes to reduce microbial growth and odor formation.
ZPT Zinc Pyrithione is used in textile applications only when regulatory requirements and wash durability performance are validated.

ZPT Zinc Pyrithione is used in industrial water systems and process protection in some cases as a biocide where permitted and properly controlled.
ZPT Zinc Pyrithione is incorporated into process protection strategies to reduce microbial contamination in susceptible systems.
ZPT Zinc Pyrithione is used in formulated biocide products where dosing, exposure, and disposal are managed under regulations.

ZPT Zinc Pyrithione is valued because ZPT Zinc Pyrithione provides effective antifungal and antimicrobial action, but ZPT Zinc Pyrithione use requires careful regulatory compliance, safe handling, and performance testing based on particle size and formulation compatibility.

ZPT Zinc Pyrithione is used in anti-dandruff shampoos to control Malassezia-associated dandruff.
ZPT Zinc Pyrithione helps reduce scalp flaking and visible dandruff with regular use.
ZPT Zinc Pyrithione supports improved scalp comfort by reducing itch and irritation associated with dandruff.

ZPT Zinc Pyrithione is used in anti-seborrheic dermatitis scalp treatments in regulated OTC or cosmetic formats.
ZPT Zinc Pyrithione supports management of scalp scaling when used according to local regulations.
ZPT Zinc Pyrithione helps improve scalp hygiene by limiting fungal overgrowth on the scalp surface.

ZPT Zinc Pyrithione is used in 2-in-1 shampoo and conditioner products to provide dandruff control plus conditioning.
ZPT Zinc Pyrithione supports deposition on hair and scalp when formulated with suitable conditioning systems.
ZPT Zinc Pyrithione helps maintain anti-dandruff efficacy while improving hair feel.

ZPT Zinc Pyrithione is used in scalp tonics and rinse-off scalp lotions in some markets where permitted.
ZPT Zinc Pyrithione supports targeted application to problem scalp zones in rinse-off routines.
ZPT Zinc Pyrithione helps reduce recurrence of flakes between washes in some user routines.

ZPT Zinc Pyrithione is used in medicated body washes for fungal-prone skin areas in regulated product categories.
ZPT Zinc Pyrithione supports reduction of yeast-related odor and discomfort in rinse-off skin cleansing.
ZPT Zinc Pyrithione helps improve skin cleanliness when used as directed and where permitted.

ZPT Zinc Pyrithione is used in bar soaps and syndet bars as an antimicrobial additive in some markets where allowed.
ZPT Zinc Pyrithione supports microbial control on the skin surface in rinse-off cleansing formats.
ZPT Zinc Pyrithione helps reduce odor-causing microbial growth in targeted cleansing products.

ZPT Zinc Pyrithione is used in deodorant and antiperspirant concepts in limited, regulated applications where permitted.
ZPT Zinc Pyrithione supports odor control by reducing microbial activity responsible for malodor formation.
ZPT Zinc Pyrithione helps extend freshness perception in compatible deodorant systems.

ZPT Zinc Pyrithione is used in leave-on scalp products only where local regulations explicitly allow such use.
ZPT Zinc Pyrithione supports extended-contact antifungal performance in compliant leave-on formats.
ZPT Zinc Pyrithione helps reduce persistent flaking risk when deposition and safety limits are respected.

ZPT Zinc Pyrithione is used in paints and coatings as a dry-film preservative to prevent mold and mildew growth.
ZPT Zinc Pyrithione supports longer service life of coatings exposed to humidity and condensation.
ZPT Zinc Pyrithione helps reduce staining and coating degradation caused by fungal growth.

ZPT Zinc Pyrithione is used in water-based architectural coatings to protect the cured film from microbial attack.
ZPT Zinc Pyrithione supports improved appearance retention on interior walls in damp rooms.
ZPT Zinc Pyrithione helps reduce biofilm-like discoloration on coated surfaces.

ZPT Zinc Pyrithione is used in exterior coatings to reduce algae and fungal growth on painted facades in some systems.
ZPT Zinc Pyrithione supports reduced green growth and mildew spotting on exterior paint films.
ZPT Zinc Pyrithione helps improve maintenance intervals by limiting biological fouling where permitted.

ZPT Zinc Pyrithione is used in adhesives and sealants as an in-can preservative and film preservative in some formulations.
ZPT Zinc Pyrithione supports protection against mold growth on sealant surfaces in humid environments.
ZPT Zinc Pyrithione helps reduce spoilage of water-based adhesives during storage when properly dosed.

ZPT Zinc Pyrithione is used in polymer and plastic compounding as an antimicrobial additive in selected applications.
ZPT Zinc Pyrithione supports odor control and microbial resistance in plastic parts exposed to moisture.
ZPT Zinc Pyrithione helps protect polymer surfaces from mildew staining in compatible systems.

ZPT Zinc Pyrithione is used in PVC, polyurethane, and elastomer articles to reduce fungal growth in humid service conditions.
ZPT Zinc Pyrithione supports cleaner-looking surfaces in footwear components and flexible parts.
ZPT Zinc Pyrithione helps reduce material deterioration driven by microbial colonization in some environments.

ZPT Zinc Pyrithione is used in textiles and technical fabrics as an antimicrobial finish in some markets where permitted.
ZPT Zinc Pyrithione supports odor reduction in socks, sportswear, and workwear by limiting microbial growth.
ZPT Zinc Pyrithione helps improve hygiene performance of treated fabrics when durability and compliance are validated.

ZPT Zinc Pyrithione is used in leather and synthetic leather to reduce mildew growth during storage and transport.
ZPT Zinc Pyrithione supports protection of leather goods in high-humidity logistics conditions.
ZPT Zinc Pyrithione helps reduce surface spotting and odor formation on stored leather.

ZPT Zinc Pyrithione is used in marine coatings historically as an antifouling biocide in some systems where permitted.
ZPT Zinc Pyrithione supports reduction of biofouling on submerged surfaces in compliant antifouling programs.
ZPT Zinc Pyrithione helps maintain hydrodynamic performance by limiting organism attachment where regulations allow.

ZPT Zinc Pyrithione is used in industrial water systems and cooling circuits as a biocide concept only under regulated programs.
ZPT Zinc Pyrithione supports control of microbial growth that contributes to slime and fouling in controlled dosing.
ZPT Zinc Pyrithione helps protect heat-transfer efficiency by limiting biological buildup in compliant systems.

ZPT Zinc Pyrithione is used in metalworking fluids as a biocide component in some formulations where permitted.
ZPT Zinc Pyrithione supports microbial stability of emulsions and reduces rancid odor development.
ZPT Zinc Pyrithione helps extend fluid life by limiting bacterial and fungal growth in controlled programs.

ZPT Zinc Pyrithione is used in paper and packaging coatings to reduce mold growth on coated surfaces in niche applications.
ZPT Zinc Pyrithione supports improved storage stability of coated papers in humid warehouses.
ZPT Zinc Pyrithione helps reduce surface discoloration caused by fungal growth on coated substrates.

ZPT Zinc Pyrithione is used in laboratory microbiology to study antifungal mechanisms and susceptibility.
ZPT Zinc Pyrithione supports screening of fungal growth inhibition in controlled assays.
ZPT Zinc Pyrithione helps evaluate activity against yeasts and molds in research.

ZPT Zinc Pyrithione is used in formulation development to improve deposition of insoluble particles onto hair and scalp.
ZPT Zinc Pyrithione supports use of suspending agents and rheology control for stable products.
ZPT Zinc Pyrithione helps maintain uniform dosing of the active throughout shelf life.

ZPT Zinc Pyrithione is used in pearlescent anti-dandruff shampoos to maintain stable appearance with suspended solids.
ZPT Zinc Pyrithione supports stable visual quality by keeping particles evenly distributed.
ZPT Zinc Pyrithione helps reduce sedimentation and caking in finished shampoos.

ZPT Zinc Pyrithione is used in quality control to verify assay and particle size distribution for consistent performance.
ZPT Zinc Pyrithione supports specification compliance for heavy metals and impurities.
ZPT Zinc Pyrithione helps ensure repeatable efficacy and stability in finished formulations.

ZPT Zinc Pyrithione is used in regulatory compliance workflows to meet labeling and permitted-use requirements.
ZPT Zinc Pyrithione supports standardized documentation of active concentration and product category.
ZPT Zinc Pyrithione helps manufacturers maintain compliance with local cosmetic, OTC, or biocidal rules.

ZPT Zinc Pyrithione is used in R&D to compare biocidal actives for mold control in coatings and sealants.
ZPT Zinc Pyrithione supports benchmarking of dry-film protection versus alternative preservatives.
ZPT Zinc Pyrithione helps guide preservative choice based on humidity exposure and regulatory constraints.

ZPT Zinc Pyrithione is used in durability testing of coatings to evaluate mildew resistance under accelerated exposure.
ZPT Zinc Pyrithione supports fungal challenge tests and humidity chamber evaluations.
ZPT Zinc Pyrithione helps quantify performance by reducing fungal growth ratings on coated panels.

ZPT Zinc Pyrithione is used in polymer product development to reduce odor and microbial staining on plastic surfaces.
ZPT Zinc Pyrithione supports improved hygiene performance in moisture-exposed plastic goods.
ZPT Zinc Pyrithione helps reduce visible mildew growth in storage and use environments.

ZPT Zinc Pyrithione is used in supply chain specification setting for antimicrobial additives in personal care and coatings.
ZPT Zinc Pyrithione supports consistent purchasing specifications for assay and particle properties.
ZPT Zinc Pyrithione helps maintain predictable performance across manufacturing sites.

ZPT Zinc Pyrithione is used in manufacturing to improve handling by using pre-dispersed forms that reduce dust exposure.
ZPT Zinc Pyrithione supports safer processing versus powder charging in some plants.
ZPT Zinc Pyrithione helps improve batch turnaround by simplifying dispersion steps.

ZPT Zinc Pyrithione is used in training programs for formulators as a case study in insoluble active delivery and suspension stability.
ZPT Zinc Pyrithione supports education on particle suspension, deposition, and regulatory limits.
ZPT Zinc Pyrithione helps illustrate why dispersion quality controls efficacy in rinse-off products.

ZPT Zinc Pyrithione is used in laboratory screening of synergists that improve antifungal performance in coatings.
ZPT Zinc Pyrithione supports evaluation of co-biocides and binders under humidity stress.
ZPT Zinc Pyrithione helps optimize mildew resistance while managing leaching and stability.

ZPT Zinc Pyrithione is used in formulation troubleshooting when settling, caking, or inconsistent anti-dandruff performance occurs.
ZPT Zinc Pyrithione supports corrective adjustments to rheology and dispersing systems.
ZPT Zinc Pyrithione helps maintain uniform active delivery and consistent product performance.

ZPT Zinc Pyrithione is used in product development to reduce fogging and odor in automotive interiors by choosing low-volatility preservative systems.
ZPT Zinc Pyrithione supports lower emissions compared with some volatile preservative options in certain systems.
ZPT Zinc Pyrithione helps improve long-term appearance of coated interior parts in humid exposure.

DESCRIPTION

ZPT Zinc Pyrithione is a zinc salt of pyrithione that works by disrupting microbial membrane transport and energy metabolism, leading to growth inhibition and cell death in susceptible organisms.
ZPT Zinc Pyrithione is poorly soluble in water, so ZPT Zinc Pyrithione is typically delivered as a suspended particulate, and dispersion quality strongly affects performance and stability.
ZPT Zinc Pyrithione efficacy in shampoos depends on deposition onto the scalp and contact time, so ZPT Zinc Pyrithione is formulated with surfactants and polymers that support uniform suspension and deposition.

ZPT Zinc Pyrithione can be deactivated by strong chelating agents and can be sensitive to certain formulation conditions, so compatibility with EDTA-like chelants and high ionic environments should be evaluated.
ZPT Zinc Pyrithione particle size distribution influences visual appearance, suspension stability, and bioavailability at the skin surface, so controlled milling and dispersion are important.
ZPT Zinc Pyrithione is subject to regulatory restrictions in some regions and product categories, and permitted concentration limits and product types can vary by market and time.

ZPT Zinc Pyrithione should be stored in tightly closed containers and protected from moisture and excessive heat.
ZPT Zinc Pyrithione powders can generate dust, and inhalation should be avoided through dust control and PPE.
ZPT Zinc Pyrithione should be handled only by trained personnel and used according to supplier specifications, safety documentation, and applicable regulations.

PROPERTIES

Chemical Formula: C10H8N2O2S2Zn
Molecular Weight: 317.70 g/mol
Common Name: ZPT Zinc Pyrithione
Chemical Type: Zinc pyrithione coordination compound; antimicrobial active
Appearance: White to off-white powder or dispersion (grade dependent)
Odor: Slight characteristic odor (grade dependent)
Solubility: Very low solubility in water; used as a suspension or dispersion
Particle Size: Grade dependent; influences suspension stability and efficacy
Stability: Sensitive to chelants and some formulation conditions; protect from contamination and extreme pH
Mode of Action: Antifungal and antimicrobial via disruption of microbial processes (functional description)
Use Level: Market- and regulation-dependent; formulation dependent
Storage Temperature: 5–25°C, tightly closed, protect from moisture and excessive heat
Shelf Life: Typically 24 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during weighing and powder transfer.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water and seek medical attention promptly.
Do not induce vomiting unless directed by medical personnel.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves, safety glasses, and dust protection as needed.
Avoid generating dust and avoid inhalation of fine particles.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use local exhaust or general ventilation where dust may be generated.
Maintain good airflow during weighing, charging, and blending operations.
Minimize airborne particulate accumulation in enclosed areas.

Storage:
Store in tightly closed containers in a cool, dry place protected from moisture.
Protect from excessive heat and direct sunlight to maintain stability.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Avoid dust generation and sweep or vacuum using suitable equipment.
Collect spilled material into suitable containers for reuse or disposal according to local regulations.
Clean residues with wet wiping if needed to reduce airborne dust.

Handling Precautions:
Use ZPT Zinc Pyrithione in accordance with local cosmetic and biocide regulations and confirm permitted product types and maximum concentration.
Optimize dispersion and particle size management to maintain suspension stability and consistent antidandruff efficacy.
Avoid strong chelants and incompatible formulation conditions that can reduce activity, and verify stability with testing.